Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

01 February 2006

Insulinoma in an adolescent boy presenting as altered consciousness

Maala S. Daniel, A. Pinar Cemeroglu, Marc Schlatter

Case Rep Clin Pract Rev 2006; 7:75-77 :: ID: 449531

Abstract

Background: Insulinoma is a very rare insulin secreting tumor of the pancreas and most commonly seen
sporadically in adults. Only 10% of the cases are associated with multiple endocrine neoplasia type I (MEN-I). The diagnosis of insulinomas are usually challenging especially in pediatric age group.
Case Report: A 16 year-old boy presented with episodes of loss of consciousness with no other associated findings. He was worked-up for seizure disorder. His chemistry panel showed a blood sugar
of 34 mg/dL 3 hours after breakfast. Further work-up for hypoglycemia included a high insulin and C-peptide levels with a simultaneous blood sugar of 67 mg/dL. Proinsulin level was very high at > 1000 pmol/L (normal: 3-20). An insulin secreting pancreatic tumor was
suspected and a CT scan of the pancreas revealed a 12 mm hyperdense lesion in the anterior distal part of the pancreas. Complete resolution of the episodes were achieved after surgical removal of the insulinoma. Proinsulin and insulin concentrations dropped to normal levels following surgery.
Conclusions: Hypoglycemia should always be considered in children in the differential diagnosis of altered
consciousness. Insulinoma is a very rare but curable cause of hypoglycemia in children. Although
diagnosis of insulinoma is often quite challenging, insulin, C-peptide and especially proinsulin levels with simultaneous blood glucose measurement and imaging studies may be helpful tools for diagnosis of insulinoma.

Keywords: Insulinoma, altered consciousness, Proinsulin

Add Comment 0 Comments

128

In Press

Case report  China (mainland)

Intracranial Parasitic Fetus in a Living Infant: A Case Study with Surgical Intervention and Prognosis Anal...

Am J Case Rep In Press; DOI: 10.12659/AJCR.944371  

Case report  Jordan

Blue Toe Syndrome in Behçet’s Disease: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.943813  

Case report  South Korea

A Rare Case of Stroke in a 76-Year-Old Woman: Left Atrial Papillary Fibroelastoma as the Culprit

Am J Case Rep In Press; DOI: 10.12659/AJCR.943568  

Case report  Kosovo

A 74-Year-Old Man with Severe Comorbidities and Successful Abdominal Aortic Aneurysm Repair with Thoracic S...

Am J Case Rep In Press; DOI: 10.12659/AJCR.943702  

Most Viewed Current Articles

07 Mar 2024 : Case report  USA 38,296

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

10 Jan 2022 : Case report  Germany 31,112

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

19 Jul 2022 : Case report  Saudi Arabia 17,714

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

23 Feb 2022 : Case report  USA 17,684

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923