01 February 2006
Case Rep Clin Pract Rev 2006; 7:100-102 :: ID: 451680
Background: Desmoid tumor is a rapidly growing tumor. It may be located in a variety of anatomic locations
such as abdominal, intra-abdominal and extra abdominal. However we have found only five cases in anterior mediastinum in the literature.
Case Report: A 55-year-old woman presented with history of dyspenea. Chest X-ray and computed tomography(CT) on admission showed a 30cm mass in the anterior mediastinal space, compressing the lungs
and adhering to chest wall, aorta and pericardium without any invasion. A diagnosis of benign
peripheral nerve sheath tumor was established by a CT-guided percutaneous needle biopsy. The mass was resected. The tumor was composed of bland spindled to stellate cells in a myxoid to highly collagenous stromal background. Tumor cells were positive for vimentin and negative for actin, EMA, CD34, cytokeratin, and S-100 protein. Pathological and immunohistochemical analyses confirmed a diagnosis of Fibromatosis. The patient has no recurrence 19 months after his operation.
Conclusions: Mediastinal fibromatosis is a rare tumor especially in the anterior mediastinum, which can mimic many benign and malignant tumors. Pathologist should consider it in differential diagnosis of
any bland spindle cell tumor especially in core needle biopsy.
Keywords: Fibromatosis, Anterior, Mediastinum, desmoid tumor
27 Jan 2023 : Case reportA 37-Year-Old Man with Familial Hereditary Hemorrhagic Telangiectasia and Pulmonary Arteriovenous Malformat...
Am J Case Rep In Press; DOI: 10.12659/AJCR.938548
26 Jan 2023 : Case reportA 39-Year-Old Woman with Endometriosis Who Developed a Subcapsular Liver Hematoma Following Laparotomic Sur...
Am J Case Rep In Press; DOI: 10.12659/AJCR.938169
26 Jan 2023 : Case reportOptic Neuritis as a Consequence of Long-Term Medical Treatment Using Anastrozole: A Case Report
Am J Case Rep In Press; DOI: 10.12659/AJCR.939026
Most Viewed Current Articles
13 Jul 2022 : Case reportWhistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound
Am J Case Rep 2022; 23:e936441
06 Dec 2021 : Case reportLipedema Can Be Treated Non-Surgically: A Report of 5 Cases
Am J Case Rep 2021; 22:e934406
23 Feb 2022 : Case reportPenile Necrosis Associated with Local Intravenous Injection of Cocaine
Am J Case Rep 2022; 23:e935250