Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

01 February 2006

Venlafaxine HCl in the treatment of painful peripheral uremic neuropathy: a case report

Ali Kemal Kadiroglu , Dede Sit , Hasan Kayabasi , Emin Yilmaz , Bunyamin Isikoglu

Case Rep Clin Pract Rev 2006; 7:159-161 :: ID: 452156

Abstract

Background: It is well known that uremia may lead symmetric sensorimotor polyneuropathy that tends to
affect the lower limbs compared to upper limbs. It typically involves the legs than the arms. Clinical manifestations include paresthesia, painful dysesthesia, weakness in the legs and arms.
The traditional tricyclic antidepressants (TCA) are commonly used in the treatment of painful peripheral polyneuropathy. Venlafaxine is a serotonin noradrenaline reuptake inhibitor that may have analgesic effect on painful peripheral polyneuropathy.
Case Report: Venlafaxine extended release capsule (Effexor 75mg XR, Wyeth) was administered to a 49 years old female patient who has been under hemodialysis therapy for 7 years. She complained of
bilateral numbness, pain, pin-pricking and burning in her feet that increasing in the evening. She was also suffered from insomnia for two months. The patient’s symptoms were resolved in two weeks after beginning to the therapy but the intensity of pain continued minimaly and the patients demonstrated effective improvements at her insomnia in this period. Venlafaxine was well tolerated and there were no side effects such as nasuea, elevated blood pressure and
dizziness.
Conclusions: Venlafaxine relieved the symptoms of the uremic polyneuropathy and it was effective in
insomnia.

Keywords: Venlafaxine HCl, painful peripheral polyneuropathy, Uremia

Add Comment 0 Comments

366

In Press

Case report  Greece

Endovascular Embolization in Acquired Hemophilia A: A Case Study Highlighting Diagnostic and Therapeutic St...

Am J Case Rep In Press; DOI: 10.12659/AJCR.948268  

Case report  USA

Recognizing Exocrine Pancreatic Insufficiency in Patients with Diabetes: A Case Study

Am J Case Rep In Press; DOI: 10.12659/AJCR.948283  

Case report  Japan

An 88-Year-Old Woman with a 33-Year History of Idiopathic Portal Hypertension Presenting with Hepatocellula...

Am J Case Rep In Press; DOI: 10.12659/AJCR.947725  

Case report  Poland

Adult Hemophagocytic Lymphohistiocytosis (HLH) with Neurological Involvement: Diagnostic Complexities – A C...

Am J Case Rep In Press; DOI: 10.12659/AJCR.947694  

Most Viewed Current Articles

21 Jun 2024 : Case report  China (mainland) 102,058

Intracranial Parasitic Fetus in a Living Infant: A Case Study with Surgical Intervention and Prognosis Anal...

DOI :10.12659/AJCR.944371

Am J Case Rep 2024; 25:e944371

0:00

07 Mar 2024 : Case report  USA 54,550

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

20 Nov 2023 : Case report  Saudi Arabia 38,308

Azithromycin Treatment for Acne Vulgaris: A Case Report on the Risk of Clostridioides difficile Infection

DOI :10.12659/AJCR.941424

Am J Case Rep 2023; 24:e941424

0:00

07 Jul 2023 : Case report  Saudi Arabia 26,047

A Classical Case of Cesarean Scar Endometriosis in a 35-Year-Old Woman Presenting with Cyclical Abdominal P...

DOI :10.12659/AJCR.940200

Am J Case Rep 2023; 24:e940200

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923