Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

01 February 2006

Pyothorax asscociated lymphoma – a case report and review of literature

Muhammad Ashraf Sharif, Nadira Mamoon, Shahid Jamal, Sajid Mushtaq

Case Rep Clin Pract Rev 2006; 7:228-231 :: ID: 458593

Abstract

Background: Pyothorax-associated lymphoma (PAL) is a rare lymphoid malignancy often associated with
artificial pneumothorax for the treatment of pulmonary tuberculosis. Most cases of PAL have
been described by Japanese investigators and only a few cases have been reported in western
literature. Although tuberculosis is a common disease in Pakistani population but to the best of
our knowledge this case is the first to be documented in Pakistan.
Case Report: A 76 years old male patient presented with a history of pain in the left lower chest and dry
persistent cough. Computed tomography (CT) scan showed a pleural based mass in the left para-vertebral gutter. Histopathological examination of the pleural peel revealed extensive fibrosis, necrosis and monotonous sheets of atypical, medium to large sized lymphoid cells. Immunohistochemical examination showed uniform positivity of the lymphoid cells for Leukocyte common antigen (LCA) and CD-20. Epstein Barr virus (EBV) expression by latent membrane
protein 1 (LMP-1) was also confirmed immuno-histochemically. A final diagnosis of pyothorax
associated lymphoma was made.
Conclusions: Pyothorax associated lymphoma is associated with a poor prognosis and a median survival of less than one year. The purpose of reporting this case is that one may come across such cases but with a high index of suspicion immunohistochemistry is the answer to final diagnosis.

Keywords: Tuberculosis, pyothorax

Add Comment 0 Comments

In Press

08 Jun 2023 : Case report  Latvia

Chylothorax: A Tangled Road to Definitive Diagnosis of Non-Hodgkin Lymphoma

Am J Case Rep In Press; DOI: 10.12659/AJCR.939098  

06 Jun 2023 : Case report  Saudi Arabia

A Classical Case of Cesarean Scar Endometriosis in a 35-Year-Old Woman Presenting with Cyclical Abdominal P...

Am J Case Rep In Press; DOI: 10.12659/AJCR.940200  

05 Jun 2023 : Case report  USA

Peri-Hilar Cystic Lymphangioma Mimicking a Biliary Cystic Lesion Causing Biliary Obstruction: A Case Report...

Am J Case Rep In Press; DOI: 10.12659/AJCR.939421  

05 Jun 2023 : Case report  Palestinian Territory, Occupied

Recurrent Bioprosthetic Valve Serratia marcescens Endocarditis in Intravenous Drug Users

Am J Case Rep In Press; DOI: 10.12659/AJCR.939292  

Most Viewed Current Articles

06 Dec 2021 : Case report  Brazil

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

13 Jul 2022 : Case report  USA

Whistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound

DOI :10.12659/AJCR.936441

Am J Case Rep 2022; 23:e936441

07 Dec 2021 : Case report  USA

Edwardsiella tarda: A Classic Presentation of a Rare Fatal Infection, with Possible New Background Risk Fac...

DOI :10.12659/AJCR.934347

Am J Case Rep 2021; 22:e934347

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923