Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

01 March 2002

Garré type periostitis ossificans: effective antibiotic therapy case report and literature review

Jan Styczyński, Piotr Biliński, Władysław Lasek, Anna Gajewska-Guryn, Mariusz Wysocki, Anna Balcar-Boroń

Case Rep Clin Pract Rev 2002; 3(1):46-50 :: ID: 475119


Background: Garré type periostitis ossificans is a rare disease observed in children and young adults. It is a chronic, infective pathologic change of bone tissue, with a mild course, affecting portions of long bone shafts and causing their sclerotization and thickening. Small granulation or cicatrization foci are present in the marrow cavity, without purulence and bone defects. The predominant clinical symptom is dull pain, usually nocturnal.
Generalized symptoms or signs of local inflammation are rare.
Case report: A course of Garré type periostitis ossificans located in the tibia of an 11-year-old boy is described. Laboratory tests and USG of the lesion site did not reveal any abnormalities. X-ray and CT images showed
a spindle-shaped thickening of the tibial shaft, especially in the cortical layer, and narrowing of the marrow cavity, without periosteal reaction or soft tissue lesions. Scintigraphy of the skeletal system revealed enhanced radioligand
uptake by the affected site. Differential diagnostics excluded osteogenic sarcoma, Ewing sarcoma, benign osteoma, cartilaginous tissue tumors, Langerhans cell histiocytosis and fibrous dysplasia. After antibiotic
treatment, the clinical symptoms subsided. However, no evolution of radiological changes was observed. The boy has remained asymptomatic during 3-year follow-up.
Conclusions: Garré type periostitis ossificans should be taken into consideration in the differential diagnosis of bone diseases in children. The diagnosis is established on the basis of clinical and radiological presentation.
Long-term antibiotic therapy may bring beneficial clinical effects. However, radiological changes of the affected bone may persist for a long time.

Keywords: Garré type periostitis ossificans, bone tumor

Add Comment 0 Comments


In Press

05 Mar 2024 : Case report  Saudi Arabia

Simultaneous Transcatheter Closure of a Ventricular Septal Defect and Pulmonary Valvuloplasty: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.942032  

06 Mar 2024 : Case report  Saudi Arabia

Successful Healing of Periapical Pathology with Partial Pulpotomy in a Mature Permanent Molar: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.942937  

12 Mar 2024 : Case report  Japan

Successful Treatment of Lithium-Induced Nephrogenic Diabetes Insipidus with Celecoxib: A Promising Therapeu...

Am J Case Rep In Press; DOI: 10.12659/AJCR.943244  

13 Mar 2024 : Case report  Taiwan

Recurrent Marginal Zone Lymphoma with Bone Marrow Involvement Detected by ¹⁸F-FDG PET/CT and Biopsy: A Diag...

Am J Case Rep In Press; DOI: 10.12659/AJCR.943275  

Most Viewed Current Articles

07 Mar 2024 : Case report  USA

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133


10 Jan 2022 : Case report  Germany

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

19 Jul 2022 : Case report  Saudi Arabia

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923