Background: Postpartum period may aggravate the symptoms of psychosis and this effect may be attributed to the triggering effect of the sudden drop of plasma pregnancy hormone levels immediately after delivery. Mesial temporal lobe resection may be another factor for the exacerbation of schizophrenia like psychosis.
Case Report: We presented a 32-year-old Caucasian female patient who had temporal lobectomy, before her pregnancy and developed a psychotic disorder during the post partum period.
Conclusions: In this case report, the possible relationship among temporal lobe resection, postnatal period, and psychotic disorder is discussed.

Keywords: Postpartum Period, temporal lobe resection, psychosis