Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

27 March 2008

Ancient schwannoma of the thyroid: report of a case and comprehensive review of the literature

Gaetano Magro, Antonietta Torrisi, Paolo Amico, Claudio Lo Presti, Giuseppe Ippolito, Orazio Ippolito

Am J Case Rep 2008; 9:182-187 :: ID: 849822


Background: Ancient schwannoma is an unusual histological variant of schwannoma, which usually arises in the head and neck, thorax, retroperitoneum, pelvis, and extremities. Although 15 cases of primary thyroid schwannomas have been reported in the literature so far, no case of ancient schwannoma has been described in this gland.
Case Report: A 52-year-old woman presented with an asymptomatic right lower neck swelling, which ultrasound scan revealed to be a 3-cm solid nodule in the right thyroid lobe. Preoperative FNAB, revealing only infl ammatory cells, was not conclusive for diagnosis. The patient underwent surgery. The nodule corresponded to a spindle cell tumour with morphological and immunohostochemical features consistent with the diagnosis of “ancient schwannoma”. A review of the literature revealed only 15 cases of intrathyroidal typical schwannomas reported so far. We herein report the first case of a primary thyroid ancient schwannoma, emphasizing its clinico-pathologic features and the differential diagnosis with other primary spindle cell tumour-like and tumour lesions.
Conclusions: We herein report the clinical, radiological, morphological and immunohistochemical features of the fi rst case of an ancient schwannoma occurring within the thyroid gland. As this tumour shows some worrisome morphological features, i.e. atypical cells, awareness and recognition of this rare variant of schwannoma in the thyroid gland is important to avoid a misdiagnosis of malignancy.

Keywords: differential diagnosis, ancient schwannoma, thyroid, review

Add Comment 0 Comments

826 1

In Press

09 Jun 2023 : Case report  Japan

Venous Thoracic Outlet Syndrome with an Upper Extremity Deep Vein Thrombosis Caused by a Dislocated Clavicl...

Am J Case Rep In Press; DOI: 10.12659/AJCR.939250  

08 Jun 2023 : Case report  Latvia

Chylothorax: A Tangled Road to Definitive Diagnosis of Non-Hodgkin Lymphoma

Am J Case Rep In Press; DOI: 10.12659/AJCR.939098  

06 Jun 2023 : Case report  Saudi Arabia

A Classical Case of Cesarean Scar Endometriosis in a 35-Year-Old Woman Presenting with Cyclical Abdominal P...

Am J Case Rep In Press; DOI: 10.12659/AJCR.940200  

05 Jun 2023 : Case report  USA

Peri-Hilar Cystic Lymphangioma Mimicking a Biliary Cystic Lesion Causing Biliary Obstruction: A Case Report...

Am J Case Rep In Press; DOI: 10.12659/AJCR.939421  

Most Viewed Current Articles

06 Dec 2021 : Case report  Brazil

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

13 Jul 2022 : Case report  USA

Whistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound

DOI :10.12659/AJCR.936441

Am J Case Rep 2022; 23:e936441

07 Dec 2021 : Case report  USA

Edwardsiella tarda: A Classic Presentation of a Rare Fatal Infection, with Possible New Background Risk Fac...

DOI :10.12659/AJCR.934347

Am J Case Rep 2021; 22:e934347

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923