Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

27 March 2008

Ancient schwannoma of the thyroid: report of a case and comprehensive review of the literature

Gaetano Magro, Antonietta Torrisi, Paolo Amico, Claudio Lo Presti, Giuseppe Ippolito, Orazio Ippolito

Am J Case Rep 2008; 9:182-187 :: ID: 849822


Background: Ancient schwannoma is an unusual histological variant of schwannoma, which usually arises in the head and neck, thorax, retroperitoneum, pelvis, and extremities. Although 15 cases of primary thyroid schwannomas have been reported in the literature so far, no case of ancient schwannoma has been described in this gland.
Case Report: A 52-year-old woman presented with an asymptomatic right lower neck swelling, which ultrasound scan revealed to be a 3-cm solid nodule in the right thyroid lobe. Preoperative FNAB, revealing only infl ammatory cells, was not conclusive for diagnosis. The patient underwent surgery. The nodule corresponded to a spindle cell tumour with morphological and immunohostochemical features consistent with the diagnosis of “ancient schwannoma”. A review of the literature revealed only 15 cases of intrathyroidal typical schwannomas reported so far. We herein report the first case of a primary thyroid ancient schwannoma, emphasizing its clinico-pathologic features and the differential diagnosis with other primary spindle cell tumour-like and tumour lesions.
Conclusions: We herein report the clinical, radiological, morphological and immunohistochemical features of the fi rst case of an ancient schwannoma occurring within the thyroid gland. As this tumour shows some worrisome morphological features, i.e. atypical cells, awareness and recognition of this rare variant of schwannoma in the thyroid gland is important to avoid a misdiagnosis of malignancy.

Keywords: differential diagnosis, ancient schwannoma, thyroid, review

Add Comment 0 Comments

In Press

12 Mar 2024 : Case report  Japan

Successful Treatment of Lithium-Induced Nephrogenic Diabetes Insipidus with Celecoxib: A Promising Therapeu...

Am J Case Rep In Press; DOI: 10.12659/AJCR.943244  


13 Mar 2024 : Case report  Taiwan

Recurrent Marginal Zone Lymphoma with Bone Marrow Involvement Detected by ¹⁸F-FDG PET/CT and Biopsy: A Diag...

Am J Case Rep In Press; DOI: 10.12659/AJCR.943275  

13 Mar 2024 : Case report  Denmark

Unveiling the Temporal Aspect of MRI Tattoo Reactions: A Prospective Evaluation of a Newly-Acquired Tattoo ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.943411  

13 Mar 2024 : Case report  Singapore

Cardiac and Intramuscular Metastases Following Nephroureterectomy for Metachronous Urothelial Carcinoma

Am J Case Rep In Press; DOI: 10.12659/AJCR.942864  

Most Viewed Current Articles

07 Mar 2024 : Case report  USA

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133


10 Jan 2022 : Case report  Germany

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

19 Jul 2022 : Case report  Saudi Arabia

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923