29 October 2009
Phentermine associated ischemic colitis in a young woman
Atif S Siddiqui, Jawairia ShakilAm J Case Rep 2009; 10:183-185 :: ID: 878247
Abstract
Background: Drug reactions have been associated with ischemic colitis. Phentermine, an appetite suppressant has been associated with pulmonary hypertension and cardiac valvular diseases. However, association of phentermine with ischemic colitis is rarely reported.
Case Report: A 37 year old young female with no past medical problems presented with abdominal pain and bloody diarrhea. Computed tomography (CT) abdomen and pelvis showed pan colitis. Her clinical condition was rapidly deteriorated and she underwent exploratory laparotomy and required total colectomy with ileoproctostomy because of the ischemic bowel. She did not have any risk factors associated with ischemic colitis. Further evaluation revealed that she was taking phentermine for six months for weight reduction. She was gradually improved and discharged from the hospital and did not resume her weight loss medication.
Conclusions: Phentermine may be causative of ischemic colitis and further research is needed to establish an epidemiologic link and the underlying mechanism.
Keywords: Sympathomimetic, ischemic colitis, Phentermine
In Press
12 Feb 2024 : Case report
Erdheim-Chester Disease Occult on Radiographs and CT but Visible on MRI and PETAm J Case Rep In Press; DOI: 10.12659/AJCR.941169
12 Feb 2024 : Case report
Surgical Treatment of Spontaneous Superficial Temporal Artery Arteriovenous Malformation: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.942839
13 Feb 2024 : Case report
Warfarin Woes: A Rare Case of Hemoperitoneum with Intramural Small Bowel HematomaAm J Case Rep In Press; DOI: 10.12659/AJCR.943519
13 Feb 2024 : Case report
Hemorrhagic Presentation in Primary Central Nervous System Lymphoma: A Case StudyAm J Case Rep In Press; DOI: 10.12659/AJCR.942951
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250