Background: To reveal the characteristic features of a rare clinical disease of primary schwannoma of the adrenal gland.
Case Report: The clinical and pathologic features are reported of the case of a 39-year-old man detected incidentally during abdominal examinations during his medical health checkup. A non-functioning neurogenic tumor was suspected as a differential diagnosis by computed tomography (CT), ultrasonography, and magnetic resonance imaging (MRI). CT scans showed well-circumscribed lowdensity adrenal masses, while MRI revealed the tumors to be heterogeneous, with low intensity on T1-weighted images and high intensity on T2-weighted images. The patient underwent retroperitoneal laparoscopic resection of the tumor. Histopathologically, the tumor was characterized by a proliferation of cytologically bland spindle cells and diagnosed as benign schwannoma. The diagnosis
was supported by positive immunoreactivity for S-100 protein. This patient was discharged from the hospital on the seventh postoperative day without any complications.
Conclusions: Because of its rarity, schwannoma occurring at this particular site can pose problems in diagnosis and should be distinguished from other spindle cell lesions of the adrenal gland. A retroperitoneal laparoscopic surgical technique is safe and feasible for diagnosis and treatment.

Keywords: adrenal gland, benign schwannoma, S-100 protein