Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

05 July 2010

Melanin-containing cells of the endometrium (so-called endometrial melanosis)

Handan Aker, Hatice Ozer, Ruhnaz Yılmaz

Am J Case Rep 2010; 11:134-137 :: ID: 881002

Abstract

Background: The presence of melanin-containing cells is an occasional finding in the female genital tract. The origin and clinical significance of these cells are debatable and still unknown. These lesions are described under various designations from benign to malign, such as melanosis, stromal melanocytosis or blue nevus and malign melanoma either primary or metastatic. The occurrence of melanin-containing cells in the endometrial stroma, which is designated as a blue nevus of the endometrium, has been documented only twice previously. However, searching the literature for melanosis of the endometrium, namely melanin detection in both stromal and epithelial cells, not a single report was found.
Case Report: A 45-year-old woman, having oligomenorrhea for the past 2 years, and who eventually had profuse bleeding, underwent endometrial curettage. Our case was an incidental finding of small aggregates of short spindle cells with finely granular, dark brown pigment in the curettage specimen. The histochemical characteristic of the pigment was melanin, and was also noted both within the glandular epithelial and the stromal cells.
Conclusions: As a consequence, our lesion from the endometrium might be the first documented example of extracutaneous endometrial melanosis.

Keywords: Endometrium, Melanosis, melanin, stroma, glandular epithelium

Add Comment 0 Comments

In Press

18 Jan 2024 : Case report  USA

A Case of Left-Sided Acute Appendicitis in a 45-Year-Old Man with Situs Inversus Totalis Managed by Emergen...

Am J Case Rep In Press; DOI: 10.12659/AJCR.942323  

0:00

23 Jan 2024 : Case report  USA

Cloacal Dysgenesis Sequence in a Preterm Neonate

Am J Case Rep In Press; DOI: 10.12659/AJCR.942203  

0:00

09 Feb 2024 : Case report  USA

A Case of Trauma-Related Angioedema of the Airway in a Patient on an Angiotensin Receptor Blocker

Am J Case Rep In Press; DOI: 10.12659/AJCR.943407  

0:00

30 Jan 2024 : Case report  Colombia

Bedside Ultrasound to Guide the Diagnosis and Treatment of Fulminant Right Heart Failure: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.942694  

0:00

Most Viewed Current Articles

10 Jan 2022 : Case report  Germany

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

19 Jul 2022 : Case report  Saudi Arabia

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

05 Mar 2022 : Case report  Brazil

Acute Limb Ischemia After Self-Injection of Crushed Morphine Tablets into the Radial Artery: Role of Infrar...

DOI :10.12659/AJCR.935336

Am J Case Rep 2022; 23:e935336

02 Apr 2022 : Case report  Saudi Arabia

Infective Endocarditis Caused by Pseudomonas luteola in a Pediatric Patient. A Case Report and Review of Li...

DOI :10.12659/AJCR.935743

Am J Case Rep 2022; 23:e935743

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923