Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

22 October 2010

Autoimmune pancreatitis masquerading as distal cholangiocarcinoma: A case series of two cases

Rebecca S. Lewis, Haris A. Khwaja, Andrew Wotherspoon, Jeremy N. Thompson, Aamir Z. Khan

Am J Case Rep 2010; 11:182-185 :: ID: 881209

Abstract

Background: Autoimmune pancreatitis (AIP) is a rare but distinct form of the disease with manifestations both within the pancreas and outside. Autoimmune pancreatitis can present with extrahepatic strictures which can be difficult to distinguish from malignant strictures, including cholangiocarcinoma. Elevated serum IgG4 levels are a feature of autoimmune pancreatitis and histologically the disease is characterised by a significant periductal lymphoplasmacytic infiltration rich in IgG4 positive cells.
Case Report: The following two cases represent the different treatment options available to patients presenting with malignant bile duct strictures thought to be cholangiocarcinoma which eventually proved to be due to autoimmune pancreatitis. Patient 1 is a 62 year old gentleman of South American descent, and patient 2 is a 72 year old Caucasian gentleman.
Conclusions: Pre-operative diagnosis in autoimmune-related bile duct strictures is important as it may negate the need for major complex surgery.

Keywords: autoimmune pancreatitis, Cholangiocarcinoma, pancreatic cancer

Add Comment 0 Comments

In Press

Case report  China

A 73-Year-Old Man Presenting with Shoulder Muscle Pain and a Diagnosis of Guillain-Barré Syndrome

Am J Case Rep In Press; DOI: 10.12659/AJCR.945539  

Case report  China

Diagnostic Challenges in Sporadic Creutzfeldt-Jakob Disease: A Case Study of Typical Clinical Presentation ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.945795  

Case report  China

Minimally Invasive Management of Infantile Dacryocystitis with Lacrimal Abscess: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.946588  

Case report  Poland

Varicella Zoster Virus-Induced Retinitis and Retinal Detachment in an Immunocompetent Patient: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.946011  

Most Viewed Current Articles

21 Jun 2024 : Case report  China (mainland) 88,761

Intracranial Parasitic Fetus in a Living Infant: A Case Study with Surgical Intervention and Prognosis Anal...

DOI :10.12659/AJCR.944371

Am J Case Rep 2024; 25:e944371

0:00

07 Mar 2024 : Case report  USA 50,081

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

20 Nov 2023 : Case report  Saudi Arabia 25,336

Azithromycin Treatment for Acne Vulgaris: A Case Report on the Risk of Clostridioides difficile Infection

DOI :10.12659/AJCR.941424

Am J Case Rep 2023; 24:e941424

0:00

18 Feb 2024 : Case report  Japan 22,657

A Case of Thoracic Empyema Caused by Actinomyces naeslundii

DOI :10.12659/AJCR.943030

Am J Case Rep 2024; 25:e943030

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923