Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

28 December 2010

Acute myopia and angle closure glaucoma associated with topiramate use: A case series

AliReza Dehghani, Leila Rezaei, AliReza Peyman

DOI: 10.12659/AJCR.881366

Am J Case Rep 2010; 11:241-243

Abstract

Abstract
Background: To report 7 cases of topiramate-induced angle closure glaucoma.
Case Report: We present 7 cases of angle closure glaucoma after topiramate administration for neuropsychological disorders. All patients were female. The average age of patients was 33.28 years (ranging from 19 to 44 years). The mean interval between drug administration and symptoms onset was 12.2 days (ranging from 4 to 30 days).The mean best corrected visual acuity was 3 meters counting fingers in both eyes. The mean refractive errors was –6.50 diopters (ranging from –3.00 to –12.00 diopters). The mean intraocular pressure was 44.71 mmHg (ranging from 34 to 60 mmHg). The mean normalization time of intraocular pressure was 12.30 hours (ranging from 8 to 23 hours).
Conclusions: Acute myopia and acute angle closure glaucoma are serious adverse effects of topiramate use, both of which are reversible with immediate discontinuation of the drug. Thus, obtaining the drug history of the patients is critical in evaluation of angle closure glaucoma.

Keywords: Topiramat, angle closure, Glaucoma

0 Comments

SARS-CoV-2/COVID-19

02 December 2022 : Case report  Singapore

Encephalopathy as the Only Manifestation in Simultaneous Arterial Infarct and Cerebral Venous Sinus Thrombo...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938571  

30 November 2022 : Case report  Gabon

Severe COVID-19 in 2 Kidney Transplant Patients in Gabon

Am J Case Rep In Press; DOI: 10.12659/AJCR.938003  

23 November 2022 : Case report  Grenada

Mepolizumab as a Potential Protective Factor of COVID-19 Mortality: A Case Report of Chronic Bronchitis and...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938450  

In Press

07 Dec 2022 : Case report  China (mainland)

Ureterolithiasis in Human Immunodeficiency Virus (HIV) Patients Treated with Single-Use Ureteroscope: A Cas...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938608  

05 Dec 2022 : Case report  Japan

A 75-Year-Old Woman with a 5-Year History of Controlled Type 2 Diabetes Mellitus Presenting with Polydipsia...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938482  

05 Dec 2022 : Case report  Singapore

Encephalopathy as the Only Manifestation in Simultaneous Arterial Infarct and Cerebral Venous Sinus Thrombo...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938571  

05 Dec 2022 : Case report  USA

Levofloxacin-Associated Bullous Pemphigoid in a Hemodialysis Patient After Kidney Transplant Failure

Am J Case Rep In Press; DOI: 10.12659/AJCR.938476  

Most Viewed Current Articles

13 Jul 2022 : Case report  USA

Whistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound

DOI :10.12659/AJCR.936441

Am J Case Rep 2022; 23:e936441

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

06 Dec 2021 : Case report  Brazil

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

17 Feb 2022 : Case report  Oman

Myocarditis, Pulmonary Hemorrhage, and Extensive Myositis with Rhabdomyolysis 12 Days After First Dose of P...

DOI :10.12659/AJCR.934399

Am J Case Rep 2022; 23:e934399

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923