Abstract
Background: Due to its microscopic appearance, characteristic clinical behavior, high level of recurrence and systemic spread, adenocystic carcinoma is considered as separate from other forms of glandular neoplasm. In terms of clinical behavior, it is the most deceptive tumor in the head-neck region. It most commonly involves the parotid, submandibular gland, tongue and accessory salivary glands in the palate. The clinical appearance is of a mass with hardness at palpitation and sometimes pain or sensitivity. Postoperative prosthetic defect rehabilitation is functionally and phonetically essential.
Case Report: The first patient was a 50-year-old woman with a painful swelling in the right maxillary molar and palatal region, which had persisted for the previous year and grown rapidly during the previous 2 months, and with congestion in the right side of the nose. The second patient was a 36-year-old woman complaining of swelling in the left cheek 1.5 years previously and an inability to open her mouth 5–6 months before application to our clinic, a solid mass, painful on palpitation, causing facial asymmetry along the left cheek and limiting mouth opening.
Conclusions: Our aim is to present and discuss surgical approaches adopted in cases reported as adenocystic carcinoma, which occupies a special place among malign salivary gland tumors, the first case involving the maxillary dentoalveolar structure and maxillary sinus, and the second case involving the buccal, retromaxillary, infratemporal and pterygomandibular fossa.

Keywords: Maxillofacial region, adenocystic carcinoma, The importance of CT and MR