Background: The aim of this report is to present the case of a patient with Wiskott-Aldrich syndrome (WAS) and anterior scleritis.
Case Report: An 18-year-old Caucasian male with Wiskott-Aldrich syndrome presented with redness and pain in his left eye. Scleritis was diagnosed. Treatment included topical steroids and NSAIDS, oral naproxen and acyclovir and extra subcutaneous IgG injections, in addition to those medications regularly received for his immunodeficiency. Scleritis resolved without further consequences for the eye and the patient continued receiving IgG for the immunodeficiency.
Conclusions: Scleritis should be added to the ophthalmic manifestations of Wiskott-Aldrich syndrome.

Keywords: immune deficiency, Sex Linked Recessive Inheritance, ophthalmic manifestations, Wiscott-Aldrich syndrome, X-linked thrombocytopenia, Scleritis