10 June 2026
: Case report
[In Press] Dialysis-Associated Acquired Cystic Kidney Disease as a Cause of Progressive Renal Hemorrhage in a Patient Receiving Hemodialysis: A Case Report
Management of emergency care
Xiao Huang1ABEF, Meihan Chen1BDFG, Dayong Hu1ACDGDOI: 10.12659/AJCR.953308
Am J Case Rep In Press; DOI: 10.12659/AJCR.953308
Available online: 2026-06-10, In Press, Corrected Proof
Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule
Abstract
BACKGROUND
Acquired cystic kidney disease is a known complication in patients receiving hemodialysis and one cause of spontaneous hemorrhage. Spontaneous hemorrhage of acquired cystic kidney disease in patients receiving hemodialysis was previously described as a rare condition with a poor prognosis. This report describes the case of a 68-year-old man with dialysis-associated acquired cystic kidney disease presenting with spontaneous intracystic hemorrhage.
CASE REPORT
A 68-year-old man on maintenance hemodialysis for 2 years presented with right lower abdominal and lumbar pain 5 hours after hemodialysis. Physical examination revealed percussion tenderness over the right renal region. The patient had normal coagulation functions and used low-molecular-weight heparin for anticoagulation during hemodialysis. Both the conservative management and artery embolization with digital subtraction angiography were unsuccessful. Dynamic monitoring of hemoglobin concentration indicated a downward trend. Computed tomography of the abdomen revealed progressive enlargement of the hematoma. Subsequently, the patient underwent a right nephrectomy. Postoperative gross pathological finding verified spontaneous hemorrhage caused by rupture of dialysis-associated acquired cystic kidney disease. Postoperatively, the level of hemoglobin remained stable.
CONCLUSIONS
This case with spontaneous hemorrhage of dialysis-associated acquired cystic kidney disease highlights the need for surveillance in patients receiving hemodialysis. Prompt surgical intervention is beneficial for patients with dialysis-associated acquired cystic kidney disease presenting with spontaneous hemorrhage and a persistent decline of hemoglobin.
Keywords: Hemodialysis Units, Hospital; Hemorrhage; Kidney; Nephrectomy; Case Reports
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