Rare disease

21 Aug 2026 : Case report
Histiocytic Sarcoma With Striking Clinical Improvement
Nur Farhanah
, Jessica Novia Hadiyanto
, Erlieza Roosdhania
, Dhesi Ariembi
, Enny Puji Astuti, Subiyakto Bustomi
, Eny Dyah Kurniawati
, Hermawan Istiadi
, Budi Setiawan
DOI: 10.12659/AJCR.952214
Am J Case Rep 2026; 27:e952214
730 1,074 0

21 Aug 2026 : Case report
Histiocytic Sarcoma With Striking Clinical Improvement
Nur Farhanah
, Jessica Novia Hadiyanto
, Erlieza Roosdhania
, Dhesi Ariembi
, Enny Puji Astuti, Subiyakto Bustomi
, Eny Dyah Kurniawati
, Hermawan Istiadi
, Budi Setiawan
DOI: 10.12659/AJCR.952214
Am J Case Rep 2026; 27:e952214
730 1074 0

21 Aug 2026 : Case report
Left Ventricular Summit Ventricular Tachycardia Identified by Electrocardiographic Pattern Recognition and Managed With Radiofrequency Ablation
Mariana Goes Moreira, Carina Abigail Hardy, Leandro Menezes Alves da Costa, Ana Carolina Menezes Borsoi, Rodrigo Goldenstein Schainberg, Anna Beatriz Gori Montes, Rafael Amorim Belo Nunes, Thiago Midlej Brito, Daniel Castanho Genta Pereira, Roger Pereira de Oliveira
, Thiago Luis Scudeler
DOI: 10.12659/AJCR.953321
Am J Case Rep 2026; 27:e953321
681 885 0

21 Aug 2026 : Case report
Left Ventricular Summit Ventricular Tachycardia Identified by Electrocardiographic Pattern Recognition and Managed With Radiofrequency Ablation
Mariana Goes Moreira, Carina Abigail Hardy, Leandro Menezes Alves da Costa, Ana Carolina Menezes Borsoi, Rodrigo Goldenstein Schainberg, Anna Beatriz Gori Montes, Rafael Amorim Belo Nunes, Thiago Midlej Brito, Daniel Castanho Genta Pereira, Roger Pereira de Oliveira
, Thiago Luis Scudeler
DOI: 10.12659/AJCR.953321
Am J Case Rep 2026; 27:e953321
681 885 0

19 Aug 2026 : Case report
Malignant Soft Tissue Tumor Mimicking Chronic Expanding Hematoma After a Long Clinical Course: A Case Report
Itaru Ogawa
, Yoichi Kaneuchi
, Takeo Suzuki
, Fumiya Ara
, Shoki Yamada
, Osamu Hasegawa, Michiyuki Hakozaki
, Yoshihiro Matsumoto
DOI: 10.12659/AJCR.953515
Am J Case Rep 2026; 27:e953515
685 1,010 0

19 Aug 2026 : Case report
Malignant Soft Tissue Tumor Mimicking Chronic Expanding Hematoma After a Long Clinical Course: A Case Report
Itaru Ogawa
, Yoichi Kaneuchi
, Takeo Suzuki
, Fumiya Ara
, Shoki Yamada
, Osamu Hasegawa, Michiyuki Hakozaki
, Yoshihiro Matsumoto
DOI: 10.12659/AJCR.953515
Am J Case Rep 2026; 27:e953515
685 1010 0

19 Aug 2026 : Case report
Incidental Discovery of a Fallopian Tube Mesenteric Borderline Serous Tumor During Cesarean Section: A Case Report and Literature Review
Yingmei Tuo, Dongyan Chen, Ying Geng, Lianming Liao
DOI: 10.12659/AJCR.952204
Am J Case Rep 2026; 27:e952204
696 995 0

19 Aug 2026 : Case report
Incidental Discovery of a Fallopian Tube Mesenteric Borderline Serous Tumor During Cesarean Section: A Case Report and Literature Review
Yingmei Tuo, Dongyan Chen, Ying Geng, Lianming Liao
DOI: 10.12659/AJCR.952204
Am J Case Rep 2026; 27:e952204
696 995 0

18 Aug 2026 : Case report
Long-Term Cardiac Remodeling During Migalastat Therapy in a Heterozygote Woman With Fabry Disease (N224S): A 9 Year Case Report
Clement Tan, Vaikunthan Thanabalasingam, Chaminda Sella Kapu, Matthew Hiskens, Zhihua Zhang
DOI: 10.12659/AJCR.952758
Am J Case Rep 2026; 27:e952758
733 1,017 0

18 Aug 2026 : Case report
Long-Term Cardiac Remodeling During Migalastat Therapy in a Heterozygote Woman With Fabry Disease (N224S): A 9 Year Case Report
Clement Tan, Vaikunthan Thanabalasingam, Chaminda Sella Kapu, Matthew Hiskens, Zhihua Zhang
DOI: 10.12659/AJCR.952758
Am J Case Rep 2026; 27:e952758
733 1017 0

17 Aug 2026 : Case report
A Case Report of a 64-Year-Old Man With Urothelial Carcinoma With Brain and Leptomeningeal Metastases Treated With Intrathecal Methotrexate as Part of Multimodal Management
Leland F. Damron, Leigh Kinney, Nikhita Kathuria-Prakash, Marilena Iliopoulos, Dimitrios Stefanoudakis, Lidia P. Lopez, Marah Sakkal
, Negar Khanlou, Steven D. Hart, Neda A. Moatamed, Nicolaos J. Palaskas, Alexandra Drakaki
DOI: 10.12659/AJCR.951572
Am J Case Rep 2026; 27:e951572
870 1,239 0

17 Aug 2026 : Case report
A Case Report of a 64-Year-Old Man With Urothelial Carcinoma With Brain and Leptomeningeal Metastases Treated With Intrathecal Methotrexate as Part of Multimodal Management
Leland F. Damron, Leigh Kinney, Nikhita Kathuria-Prakash, Marilena Iliopoulos, Dimitrios Stefanoudakis, Lidia P. Lopez, Marah Sakkal
, Negar Khanlou, Steven D. Hart, Neda A. Moatamed, Nicolaos J. Palaskas, Alexandra Drakaki
DOI: 10.12659/AJCR.951572
Am J Case Rep 2026; 27:e951572
870 1239 0

17 Aug 2026 : Case report
From Sight to Stridor: Recurrent Angioedema in Systemic Lupus Erythematosus Associated With Complement Activation
Seyed Khalafi, Lanna Felde
DOI: 10.12659/AJCR.953593
Am J Case Rep 2026; 27:e953593
984 1,835 0

17 Aug 2026 : Case report
From Sight to Stridor: Recurrent Angioedema in Systemic Lupus Erythematosus Associated With Complement Activation
Seyed Khalafi, Lanna Felde
DOI: 10.12659/AJCR.953593
Am J Case Rep 2026; 27:e953593
984 1835 0

16 Aug 2026 : Case report
Severe Tricuspid Regurgitation: Traumatic Papillary Muscle Rupture Mimicking Infective Endocarditis—A Case Report
Soichiro Kobayashi, Taku Omori
, Daisuke Izumi, Toshiya Tokui, Atsunobu Kasai, Kaoru Dohi
DOI: 10.12659/AJCR.952267
Am J Case Rep 2026; 27:e952267
779 1,007 0

16 Aug 2026 : Case report
Severe Tricuspid Regurgitation: Traumatic Papillary Muscle Rupture Mimicking Infective Endocarditis—A Case Report
Soichiro Kobayashi, Taku Omori
, Daisuke Izumi, Toshiya Tokui, Atsunobu Kasai, Kaoru Dohi
DOI: 10.12659/AJCR.952267
Am J Case Rep 2026; 27:e952267
779 1007 0

15 Aug 2026 : Case report
Single-Site ALK-Positive Histiocytosis With TFG-ALK Fusion: Expanding the Clinical Spectrum of This Rare Entity
Mona Dasgupta, David Horvath, Benjamin Bevill, Ashley Scheiderer, Sean Jordan
DOI: 10.12659/AJCR.952807
Am J Case Rep 2026; 27:e952807
836 1,228 0

15 Aug 2026 : Case report
Single-Site ALK-Positive Histiocytosis With TFG-ALK Fusion: Expanding the Clinical Spectrum of This Rare Entity
Mona Dasgupta, David Horvath, Benjamin Bevill, Ashley Scheiderer, Sean Jordan
DOI: 10.12659/AJCR.952807
Am J Case Rep 2026; 27:e952807
836 1228 0

14 Aug 2026 : Case report
A Rare Case of Takotsubo Cardiomyopathy Recurrence With Alternate Reverse Phenotypes
Joud Fahed
, Sara Samadani, Abdul Mohammad
, Wongelawit F. Zerihun, Mohamed H. Abdalaziz, Danhue Moodie
DOI: 10.12659/AJCR.952861
Am J Case Rep 2026; 27:e952861
885 1,187 0

14 Aug 2026 : Case report
A Rare Case of Takotsubo Cardiomyopathy Recurrence With Alternate Reverse Phenotypes
Joud Fahed
, Sara Samadani, Abdul Mohammad
, Wongelawit F. Zerihun, Mohamed H. Abdalaziz, Danhue Moodie
DOI: 10.12659/AJCR.952861
Am J Case Rep 2026; 27:e952861
885 1187 0

13 Aug 2026 : Case report
Neonatal Endogenous Endophthalmitis Complicated by Spontaneous Globe Rupture: A Case Report
Mary Robinson, Apurwa Naik
, Cigdem Ozturk, Kenneth Alexander
DOI: 10.12659/AJCR.952748
Am J Case Rep 2026; 27:e952748
812 1,098 0

13 Aug 2026 : Case report
Neonatal Endogenous Endophthalmitis Complicated by Spontaneous Globe Rupture: A Case Report
Mary Robinson, Apurwa Naik
, Cigdem Ozturk, Kenneth Alexander
DOI: 10.12659/AJCR.952748
Am J Case Rep 2026; 27:e952748
812 1098 0

10 Aug 2026 : Case report
A 42-Year-Old Woman Presenting With Pheochromocytoma Multisystem Crisis Associated With Bilateral Pheochromocytomas Due to Multiple Endocrine Neoplasia Type 2A
Akira Umemura, Ai Chida, Shigenori Kan, Saki Kuroda, Eriko Yoshida, Toshie Segawa, Yutaka Hasegawa, Yoshihiko Takahashi, Yasushi Ishigaki
, Ayaka Sato, Naoki Yanagawa
, Akira Sasaki
DOI: 10.12659/AJCR.953137
Am J Case Rep 2026; 27:e953137
824 1,081 0

10 Aug 2026 : Case report
A 42-Year-Old Woman Presenting With Pheochromocytoma Multisystem Crisis Associated With Bilateral Pheochromocytomas Due to Multiple Endocrine Neoplasia Type 2A
Akira Umemura, Ai Chida, Shigenori Kan, Saki Kuroda, Eriko Yoshida, Toshie Segawa, Yutaka Hasegawa, Yoshihiko Takahashi, Yasushi Ishigaki
, Ayaka Sato, Naoki Yanagawa
, Akira Sasaki
DOI: 10.12659/AJCR.953137
Am J Case Rep 2026; 27:e953137
824 1081 0

07 Aug 2026 : Case report
Clear Cell Carcinoma of the Left Colon: A Case Report
Mohamed Ahmed
, Abubaker K.S. Khalid
, Olive Cummins
, Kate Richards
DOI: 10.12659/AJCR.952922
Am J Case Rep 2026; 27:e952922
679 1,059 0

07 Aug 2026 : Case report
Clear Cell Carcinoma of the Left Colon: A Case Report
Mohamed Ahmed
, Abubaker K.S. Khalid
, Olive Cummins
, Kate Richards
DOI: 10.12659/AJCR.952922
Am J Case Rep 2026; 27:e952922
679 1059 0

06 Aug 2026 : Case report
Ophthalmic Manifestations of KIF11-Associated Microcephaly With or Without Chorioretinopathy, Lymphedema, or Intellectual Disability: A Case Report of a Novel Variant
Khalid A. Alanazi, Saad Mutlaq Alosaimi, Asma Alzuabi
DOI: 10.12659/AJCR.952957
Am J Case Rep 2026; 27:e952957
719 1,207 0

06 Aug 2026 : Case report
Ophthalmic Manifestations of KIF11-Associated Microcephaly With or Without Chorioretinopathy, Lymphedema, or Intellectual Disability: A Case Report of a Novel Variant
Khalid A. Alanazi, Saad Mutlaq Alosaimi, Asma Alzuabi
DOI: 10.12659/AJCR.952957
Am J Case Rep 2026; 27:e952957
719 1207 0

05 Aug 2026 : Case report
Chest Pain Due to Anomalous Origin of the Left Circumflex Artery From the Opposite Sinus of Valsalva in a 70-Year-Old Woman
Tian Luo, Kang Luo, JunBing Lin, Qiang Huang
DOI: 10.12659/AJCR.952577
Am J Case Rep 2026; 27:e952577
681 991 0

05 Aug 2026 : Case report
Chest Pain Due to Anomalous Origin of the Left Circumflex Artery From the Opposite Sinus of Valsalva in a 70-Year-Old Woman
Tian Luo, Kang Luo, JunBing Lin, Qiang Huang
DOI: 10.12659/AJCR.952577
Am J Case Rep 2026; 27:e952577
681 991 0

03 Aug 2026 : Case report
Pustules in Stevens-Johnson Syndrome
Shunya Nagata, Takaie Kuki, Miyuki Kato
DOI: 10.12659/AJCR.953161
Am J Case Rep 2026; 27:e953161
776 1,090 0

03 Aug 2026 : Case report
Pustules in Stevens-Johnson Syndrome
Shunya Nagata, Takaie Kuki, Miyuki Kato
DOI: 10.12659/AJCR.953161
Am J Case Rep 2026; 27:e953161
776 1090 0

02 Aug 2026 : Case report
Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis Presenting as Pyrexia of Unknown Origin With Splenic Masses
Nidhi Gupta, Kriti Yadav, Mythri Chittilla, Charly Almonte, Rahul Sampath
DOI: 10.12659/AJCR.952791
Am J Case Rep 2026; 27:e952791
1,017 1,403 0

02 Aug 2026 : Case report
Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis Presenting as Pyrexia of Unknown Origin With Splenic Masses
Nidhi Gupta, Kriti Yadav, Mythri Chittilla, Charly Almonte, Rahul Sampath
DOI: 10.12659/AJCR.952791
Am J Case Rep 2026; 27:e952791
1017 1403 0

01 Aug 2026 : Case report
Continuous Epidural Infusion of Hydroxyethyl Starch for Spontaneous Intracranial Hypotension: A Retrospective Case Series
Xiao-Yan Zhang
, Qiu-Li Zhang, Ying Liu, Li-Jie Zhu, Ying-Zhi Li, Xi-Ying Ye, Zhong-Jun Zhang, Yao-Xian Zhang
DOI: 10.12659/AJCR.953129
Am J Case Rep 2026; 27:e953129
642 955 0

01 Aug 2026 : Case report
Continuous Epidural Infusion of Hydroxyethyl Starch for Spontaneous Intracranial Hypotension: A Retrospective Case Series
Xiao-Yan Zhang
, Qiu-Li Zhang, Ying Liu, Li-Jie Zhu, Ying-Zhi Li, Xi-Ying Ye, Zhong-Jun Zhang, Yao-Xian Zhang
DOI: 10.12659/AJCR.953129
Am J Case Rep 2026; 27:e953129
642 955 0

31 Jul 2026 : Case report
Fournier Gangrene in an Immunocompetent Woman Following Minor Perineal Manipulation: A Case Report
DOI: 10.12659/AJCR.953136
Am J Case Rep 2026; 27:e953136
697 1,568 0

31 Jul 2026 : Case report
Fournier Gangrene in an Immunocompetent Woman Following Minor Perineal Manipulation: A Case Report
DOI: 10.12659/AJCR.953136
Am J Case Rep 2026; 27:e953136
697 1568 0

31 Jul 2026 : Case report
Unilateral Biportal Endoscopic Resection of the Posterior Arch of the Atlas for Crowned Dens Syndrome
Xuanhui Wang
, Zhenyu Wang, Xinye Li, Peilin Liu, Yanli Du, Ziqiang Zhou, Haixiong Miao
DOI: 10.12659/AJCR.953125
Am J Case Rep 2026; 27:e953125
626 1,072 0

31 Jul 2026 : Case report
Unilateral Biportal Endoscopic Resection of the Posterior Arch of the Atlas for Crowned Dens Syndrome
Xuanhui Wang
, Zhenyu Wang, Xinye Li, Peilin Liu, Yanli Du, Ziqiang Zhou, Haixiong Miao
DOI: 10.12659/AJCR.953125
Am J Case Rep 2026; 27:e953125
626 1072 0

30 Jul 2026 : Case report
Management of Shamblin Type III Carotid Body Tumor With Preoperative Embolization, Surgical Resection, and Rescue Endovascular Stroke Treatment: A Case Report
Michal S. Proczka
, Piotr Kaszczewski
, Michał M. Sajdek, Amelia Maciąg, Rafał Maciąg, Ireneusz Nawrot
, Zbigniew Gałązka
DOI: 10.12659/AJCR.951348
Am J Case Rep 2026; 27:e951348
627 967 0

30 Jul 2026 : Case report
Management of Shamblin Type III Carotid Body Tumor With Preoperative Embolization, Surgical Resection, and Rescue Endovascular Stroke Treatment: A Case Report
Michal S. Proczka
, Piotr Kaszczewski
, Michał M. Sajdek, Amelia Maciąg, Rafał Maciąg, Ireneusz Nawrot
, Zbigniew Gałązka
DOI: 10.12659/AJCR.951348
Am J Case Rep 2026; 27:e951348
627 967 0

30 Jul 2026 : Case report
Thoracic SMARCA4-Deficient Undifferentiated Tumor Presenting as a Giant Mediastinal Mass: A Case Report
Nanami Ichihashi, Motona Kumagai
, Miyako Shimasaki, Akihiro Shioya
, Sohsuke Yamada
DOI: 10.12659/AJCR.952937
Am J Case Rep 2026; 27:e952937
855 1,251 0

30 Jul 2026 : Case report
Thoracic SMARCA4-Deficient Undifferentiated Tumor Presenting as a Giant Mediastinal Mass: A Case Report
Nanami Ichihashi, Motona Kumagai
, Miyako Shimasaki, Akihiro Shioya
, Sohsuke Yamada
DOI: 10.12659/AJCR.952937
Am J Case Rep 2026; 27:e952937
855 1251 0

27 Jul 2026 : Case report
Recurrent Ischemic Strokes Caused by HSV-2–Associated Cerebral Vasculitis in Antisynthetase Syndrome
Christian M. Räz
, Benjamin Wagner
, Özgür Yaldizli, David T. Winkler, Alessandra Angelini, David Dashti, Sebastian Wirz, Mihaela Stegert, Eliška Potluková
DOI: 10.12659/AJCR.952736
Am J Case Rep 2026; 27:e952736
855 1,422 0

27 Jul 2026 : Case report
Recurrent Ischemic Strokes Caused by HSV-2–Associated Cerebral Vasculitis in Antisynthetase Syndrome
Christian M. Räz
, Benjamin Wagner
, Özgür Yaldizli, David T. Winkler, Alessandra Angelini, David Dashti, Sebastian Wirz, Mihaela Stegert, Eliška Potluková
DOI: 10.12659/AJCR.952736
Am J Case Rep 2026; 27:e952736
855 1422 0

27 Jul 2026 : Case report
Transient Cardiac Dysfunction Due to New-Onset Mitral Chordal Rupture With Concomitant Congenital Absence of the Right Coronary Artery: A Case Report
Songyan Zhang, Ying Cui, Shucheng Li
DOI: 10.12659/AJCR.952798
Am J Case Rep 2026; 27:e952798
651 1,004 0

27 Jul 2026 : Case report
Transient Cardiac Dysfunction Due to New-Onset Mitral Chordal Rupture With Concomitant Congenital Absence of the Right Coronary Artery: A Case Report
Songyan Zhang, Ying Cui, Shucheng Li
DOI: 10.12659/AJCR.952798
Am J Case Rep 2026; 27:e952798
651 1004 0

25 Jul 2026 : Case report
A 46-Year-Old Man Presenting With Chest Pain Due to Apical Hypertrophic Cardiomyopathy (Yamaguchi Syndrome) Diagnosed by Multimodal Cardiac Imaging
Mauro de Deus Passos, Daniel Lopes Marques de Araújo, Lucas de Ávila Mariano, Dilson Palhares Ferreira, Luciano Moreira Alves, Simone Nascimento dos Santos
DOI: 10.12659/AJCR.953259
Am J Case Rep 2026; 27:e953259
814 1,361 0

25 Jul 2026 : Case report
A 46-Year-Old Man Presenting With Chest Pain Due to Apical Hypertrophic Cardiomyopathy (Yamaguchi Syndrome) Diagnosed by Multimodal Cardiac Imaging
Mauro de Deus Passos, Daniel Lopes Marques de Araújo, Lucas de Ávila Mariano, Dilson Palhares Ferreira, Luciano Moreira Alves, Simone Nascimento dos Santos
DOI: 10.12659/AJCR.953259
Am J Case Rep 2026; 27:e953259
814 1361 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.954889
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.954405
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953611
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.954016
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