Rare disease

16 Aug 2026 : Case report
Severe Tricuspid Regurgitation: Traumatic Papillary Muscle Rupture Mimicking Infective Endocarditis—A Case Report
Soichiro Kobayashi, Taku Omori
, Daisuke Izumi, Toshiya Tokui, Atsunobu Kasai, Kaoru Dohi
DOI: 10.12659/AJCR.952267
Am J Case Rep 2026; 27:e952267
712 850 0

16 Aug 2026 : Case report
Severe Tricuspid Regurgitation: Traumatic Papillary Muscle Rupture Mimicking Infective Endocarditis—A Case Report
Soichiro Kobayashi, Taku Omori
, Daisuke Izumi, Toshiya Tokui, Atsunobu Kasai, Kaoru Dohi
DOI: 10.12659/AJCR.952267
Am J Case Rep 2026; 27:e952267
712 850 0

15 Aug 2026 : Case report
Single-Site ALK-Positive Histiocytosis With TFG-ALK Fusion: Expanding the Clinical Spectrum of This Rare Entity
Mona Dasgupta, David Horvath, Benjamin Bevill, Ashley Scheiderer, Sean Jordan
DOI: 10.12659/AJCR.952807
Am J Case Rep 2026; 27:e952807
760 1,030 0

15 Aug 2026 : Case report
Single-Site ALK-Positive Histiocytosis With TFG-ALK Fusion: Expanding the Clinical Spectrum of This Rare Entity
Mona Dasgupta, David Horvath, Benjamin Bevill, Ashley Scheiderer, Sean Jordan
DOI: 10.12659/AJCR.952807
Am J Case Rep 2026; 27:e952807
760 1030 0

14 Aug 2026 : Case report
A Rare Case of Takotsubo Cardiomyopathy Recurrence With Alternate Reverse Phenotypes
Joud Fahed
, Sara Samadani, Abdul Mohammad
, Wongelawit F. Zerihun, Mohamed H. Abdalaziz, Danhue Moodie
DOI: 10.12659/AJCR.952861
Am J Case Rep 2026; 27:e952861
787 1,003 0

14 Aug 2026 : Case report
A Rare Case of Takotsubo Cardiomyopathy Recurrence With Alternate Reverse Phenotypes
Joud Fahed
, Sara Samadani, Abdul Mohammad
, Wongelawit F. Zerihun, Mohamed H. Abdalaziz, Danhue Moodie
DOI: 10.12659/AJCR.952861
Am J Case Rep 2026; 27:e952861
787 1003 0

13 Aug 2026 : Case report
Neonatal Endogenous Endophthalmitis Complicated by Spontaneous Globe Rupture: A Case Report
Mary Robinson, Apurwa Naik
, Cigdem Ozturk, Kenneth Alexander
DOI: 10.12659/AJCR.952748
Am J Case Rep 2026; 27:e952748
727 923 0

13 Aug 2026 : Case report
Neonatal Endogenous Endophthalmitis Complicated by Spontaneous Globe Rupture: A Case Report
Mary Robinson, Apurwa Naik
, Cigdem Ozturk, Kenneth Alexander
DOI: 10.12659/AJCR.952748
Am J Case Rep 2026; 27:e952748
727 923 0

10 Aug 2026 : Case report
A 42-Year-Old Woman Presenting With Pheochromocytoma Multisystem Crisis Associated With Bilateral Pheochromocytomas Due to Multiple Endocrine Neoplasia Type 2A
Akira Umemura, Ai Chida, Shigenori Kan, Saki Kuroda, Eriko Yoshida, Toshie Segawa, Yutaka Hasegawa, Yoshihiko Takahashi, Yasushi Ishigaki
, Ayaka Sato, Naoki Yanagawa
, Akira Sasaki
DOI: 10.12659/AJCR.953137
Am J Case Rep 2026; 27:e953137
723 878 0

10 Aug 2026 : Case report
A 42-Year-Old Woman Presenting With Pheochromocytoma Multisystem Crisis Associated With Bilateral Pheochromocytomas Due to Multiple Endocrine Neoplasia Type 2A
Akira Umemura, Ai Chida, Shigenori Kan, Saki Kuroda, Eriko Yoshida, Toshie Segawa, Yutaka Hasegawa, Yoshihiko Takahashi, Yasushi Ishigaki
, Ayaka Sato, Naoki Yanagawa
, Akira Sasaki
DOI: 10.12659/AJCR.953137
Am J Case Rep 2026; 27:e953137
723 878 0

07 Aug 2026 : Case report
Clear Cell Carcinoma of the Left Colon: A Case Report
Mohamed Ahmed
, Abubaker K.S. Khalid
, Olive Cummins
, Kate Richards
DOI: 10.12659/AJCR.952922
Am J Case Rep 2026; 27:e952922
602 889 0

07 Aug 2026 : Case report
Clear Cell Carcinoma of the Left Colon: A Case Report
Mohamed Ahmed
, Abubaker K.S. Khalid
, Olive Cummins
, Kate Richards
DOI: 10.12659/AJCR.952922
Am J Case Rep 2026; 27:e952922
602 889 0

06 Aug 2026 : Case report
Ophthalmic Manifestations of KIF11-Associated Microcephaly With or Without Chorioretinopathy, Lymphedema, or Intellectual Disability: A Case Report of a Novel Variant
Khalid A. Alanazi, Saad Mutlaq Alosaimi, Asma Alzuabi
DOI: 10.12659/AJCR.952957
Am J Case Rep 2026; 27:e952957
643 1,025 0

06 Aug 2026 : Case report
Ophthalmic Manifestations of KIF11-Associated Microcephaly With or Without Chorioretinopathy, Lymphedema, or Intellectual Disability: A Case Report of a Novel Variant
Khalid A. Alanazi, Saad Mutlaq Alosaimi, Asma Alzuabi
DOI: 10.12659/AJCR.952957
Am J Case Rep 2026; 27:e952957
643 1025 0

05 Aug 2026 : Case report
Chest Pain Due to Anomalous Origin of the Left Circumflex Artery From the Opposite Sinus of Valsalva in a 70-Year-Old Woman
Tian Luo, Kang Luo, JunBing Lin, Qiang Huang
DOI: 10.12659/AJCR.952577
Am J Case Rep 2026; 27:e952577
615 840 0

05 Aug 2026 : Case report
Chest Pain Due to Anomalous Origin of the Left Circumflex Artery From the Opposite Sinus of Valsalva in a 70-Year-Old Woman
Tian Luo, Kang Luo, JunBing Lin, Qiang Huang
DOI: 10.12659/AJCR.952577
Am J Case Rep 2026; 27:e952577
615 840 0

03 Aug 2026 : Case report
Pustules in Stevens-Johnson Syndrome
Shunya Nagata, Takaie Kuki, Miyuki Kato
DOI: 10.12659/AJCR.953161
Am J Case Rep 2026; 27:e953161
685 923 0

03 Aug 2026 : Case report
Pustules in Stevens-Johnson Syndrome
Shunya Nagata, Takaie Kuki, Miyuki Kato
DOI: 10.12659/AJCR.953161
Am J Case Rep 2026; 27:e953161
685 923 0

02 Aug 2026 : Case report
Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis Presenting as Pyrexia of Unknown Origin With Splenic Masses
Nidhi Gupta, Kriti Yadav, Mythri Chittilla, Charly Almonte, Rahul Sampath
DOI: 10.12659/AJCR.952791
Am J Case Rep 2026; 27:e952791
897 1,181 0

02 Aug 2026 : Case report
Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis Presenting as Pyrexia of Unknown Origin With Splenic Masses
Nidhi Gupta, Kriti Yadav, Mythri Chittilla, Charly Almonte, Rahul Sampath
DOI: 10.12659/AJCR.952791
Am J Case Rep 2026; 27:e952791
897 1181 0

01 Aug 2026 : Case report
Continuous Epidural Infusion of Hydroxyethyl Starch for Spontaneous Intracranial Hypotension: A Retrospective Case Series
Xiao-Yan Zhang
, Qiu-Li Zhang, Ying Liu, Li-Jie Zhu, Ying-Zhi Li, Xi-Ying Ye, Zhong-Jun Zhang, Yao-Xian Zhang
DOI: 10.12659/AJCR.953129
Am J Case Rep 2026; 27:e953129
570 802 0

01 Aug 2026 : Case report
Continuous Epidural Infusion of Hydroxyethyl Starch for Spontaneous Intracranial Hypotension: A Retrospective Case Series
Xiao-Yan Zhang
, Qiu-Li Zhang, Ying Liu, Li-Jie Zhu, Ying-Zhi Li, Xi-Ying Ye, Zhong-Jun Zhang, Yao-Xian Zhang
DOI: 10.12659/AJCR.953129
Am J Case Rep 2026; 27:e953129
570 802 0

31 Jul 2026 : Case report
Fournier Gangrene in an Immunocompetent Woman Following Minor Perineal Manipulation: A Case Report
DOI: 10.12659/AJCR.953136
Am J Case Rep 2026; 27:e953136
624 1,317 0

31 Jul 2026 : Case report
Fournier Gangrene in an Immunocompetent Woman Following Minor Perineal Manipulation: A Case Report
DOI: 10.12659/AJCR.953136
Am J Case Rep 2026; 27:e953136
624 1317 0

31 Jul 2026 : Case report
Unilateral Biportal Endoscopic Resection of the Posterior Arch of the Atlas for Crowned Dens Syndrome
Xuanhui Wang
, Zhenyu Wang, Xinye Li, Peilin Liu, Yanli Du, Ziqiang Zhou, Haixiong Miao
DOI: 10.12659/AJCR.953125
Am J Case Rep 2026; 27:e953125
545 921 0

31 Jul 2026 : Case report
Unilateral Biportal Endoscopic Resection of the Posterior Arch of the Atlas for Crowned Dens Syndrome
Xuanhui Wang
, Zhenyu Wang, Xinye Li, Peilin Liu, Yanli Du, Ziqiang Zhou, Haixiong Miao
DOI: 10.12659/AJCR.953125
Am J Case Rep 2026; 27:e953125
545 921 0

30 Jul 2026 : Case report
Management of Shamblin Type III Carotid Body Tumor With Preoperative Embolization, Surgical Resection, and Rescue Endovascular Stroke Treatment: A Case Report
Michal S. Proczka
, Piotr Kaszczewski
, Michał M. Sajdek, Amelia Maciąg, Rafał Maciąg, Ireneusz Nawrot
, Zbigniew Gałązka
DOI: 10.12659/AJCR.951348
Am J Case Rep 2026; 27:e951348
568 780 0

30 Jul 2026 : Case report
Management of Shamblin Type III Carotid Body Tumor With Preoperative Embolization, Surgical Resection, and Rescue Endovascular Stroke Treatment: A Case Report
Michal S. Proczka
, Piotr Kaszczewski
, Michał M. Sajdek, Amelia Maciąg, Rafał Maciąg, Ireneusz Nawrot
, Zbigniew Gałązka
DOI: 10.12659/AJCR.951348
Am J Case Rep 2026; 27:e951348
568 780 0

30 Jul 2026 : Case report
Thoracic SMARCA4-Deficient Undifferentiated Tumor Presenting as a Giant Mediastinal Mass: A Case Report
Nanami Ichihashi, Motona Kumagai
, Miyako Shimasaki, Akihiro Shioya
, Sohsuke Yamada
DOI: 10.12659/AJCR.952937
Am J Case Rep 2026; 27:e952937
721 1,054 0

30 Jul 2026 : Case report
Thoracic SMARCA4-Deficient Undifferentiated Tumor Presenting as a Giant Mediastinal Mass: A Case Report
Nanami Ichihashi, Motona Kumagai
, Miyako Shimasaki, Akihiro Shioya
, Sohsuke Yamada
DOI: 10.12659/AJCR.952937
Am J Case Rep 2026; 27:e952937
721 1054 0

27 Jul 2026 : Case report
Recurrent Ischemic Strokes Caused by HSV-2–Associated Cerebral Vasculitis in Antisynthetase Syndrome
Christian M. Räz
, Benjamin Wagner
, Özgür Yaldizli, David T. Winkler, Alessandra Angelini, David Dashti, Sebastian Wirz, Mihaela Stegert, Eliška Potluková
DOI: 10.12659/AJCR.952736
Am J Case Rep 2026; 27:e952736
770 1,220 0

27 Jul 2026 : Case report
Recurrent Ischemic Strokes Caused by HSV-2–Associated Cerebral Vasculitis in Antisynthetase Syndrome
Christian M. Räz
, Benjamin Wagner
, Özgür Yaldizli, David T. Winkler, Alessandra Angelini, David Dashti, Sebastian Wirz, Mihaela Stegert, Eliška Potluková
DOI: 10.12659/AJCR.952736
Am J Case Rep 2026; 27:e952736
770 1220 0

27 Jul 2026 : Case report
Transient Cardiac Dysfunction Due to New-Onset Mitral Chordal Rupture With Concomitant Congenital Absence of the Right Coronary Artery: A Case Report
Songyan Zhang, Ying Cui, Shucheng Li
DOI: 10.12659/AJCR.952798
Am J Case Rep 2026; 27:e952798
576 863 0

27 Jul 2026 : Case report
Transient Cardiac Dysfunction Due to New-Onset Mitral Chordal Rupture With Concomitant Congenital Absence of the Right Coronary Artery: A Case Report
Songyan Zhang, Ying Cui, Shucheng Li
DOI: 10.12659/AJCR.952798
Am J Case Rep 2026; 27:e952798
576 863 0

25 Jul 2026 : Case report
A 46-Year-Old Man Presenting With Chest Pain Due to Apical Hypertrophic Cardiomyopathy (Yamaguchi Syndrome) Diagnosed by Multimodal Cardiac Imaging
Mauro de Deus Passos, Daniel Lopes Marques de Araújo, Lucas de Ávila Mariano, Dilson Palhares Ferreira, Luciano Moreira Alves, Simone Nascimento dos Santos
DOI: 10.12659/AJCR.953259
Am J Case Rep 2026; 27:e953259
725 1,146 0

25 Jul 2026 : Case report
A 46-Year-Old Man Presenting With Chest Pain Due to Apical Hypertrophic Cardiomyopathy (Yamaguchi Syndrome) Diagnosed by Multimodal Cardiac Imaging
Mauro de Deus Passos, Daniel Lopes Marques de Araújo, Lucas de Ávila Mariano, Dilson Palhares Ferreira, Luciano Moreira Alves, Simone Nascimento dos Santos
DOI: 10.12659/AJCR.953259
Am J Case Rep 2026; 27:e953259
725 1146 0

24 Jul 2026 : Case report
Adult-Onset Central Nervous System Embryonal Tumor With Neuronal Differentiation: A Diagnostic Challenge
Anh Quynh Pham, Tuyen Van Pham, Thong Minh Pham
DOI: 10.12659/AJCR.953049
Am J Case Rep 2026; 27:e953049
548 980 0

24 Jul 2026 : Case report
Adult-Onset Central Nervous System Embryonal Tumor With Neuronal Differentiation: A Diagnostic Challenge
Anh Quynh Pham, Tuyen Van Pham, Thong Minh Pham
DOI: 10.12659/AJCR.953049
Am J Case Rep 2026; 27:e953049
548 980 0

22 Jul 2026 : Case report
Diagnostic Challenges and Scientific Management of Suspected Recurrent Kikuchi-Fujimoto Disease: A Case Report
DOI: 10.12659/AJCR.952658
Am J Case Rep 2026; 27:e952658
605 984 0

22 Jul 2026 : Case report
Diagnostic Challenges and Scientific Management of Suspected Recurrent Kikuchi-Fujimoto Disease: A Case Report
DOI: 10.12659/AJCR.952658
Am J Case Rep 2026; 27:e952658
605 984 0

21 Jul 2026 : Case report
Tuberculosis in the Context of Idiopathic CD4 Lymphocytopenia: A Case Report and Literature Review
Sara M. Alwarthan
, Abir Hamad Alsaid, Ashraf Ezzat Abdelsamad Attia
, Ahmed Alsahlawi
, Shahad Ali AlZahrani
, Khalid Ghazai Alotaibi
, Hassan Naasr Al Dhneem
, Marwan Jabr Alwazzeh
DOI: 10.12659/AJCR.953101
Am J Case Rep 2026; 27:e953101
640 1,067 0

21 Jul 2026 : Case report
Tuberculosis in the Context of Idiopathic CD4 Lymphocytopenia: A Case Report and Literature Review
Sara M. Alwarthan
, Abir Hamad Alsaid, Ashraf Ezzat Abdelsamad Attia
, Ahmed Alsahlawi
, Shahad Ali AlZahrani
, Khalid Ghazai Alotaibi
, Hassan Naasr Al Dhneem
, Marwan Jabr Alwazzeh
DOI: 10.12659/AJCR.953101
Am J Case Rep 2026; 27:e953101
640 1067 0

17 Jul 2026 : Case report
Acquired Hemophilia A Revealing Occult Splenic Marginal Zone Lymphoma
Haripriya Susmitha Brahmanapalle, Alka Arora
DOI: 10.12659/AJCR.953683
Am J Case Rep 2026; 27:e953683
484 801 0

17 Jul 2026 : Case report
Acquired Hemophilia A Revealing Occult Splenic Marginal Zone Lymphoma
Haripriya Susmitha Brahmanapalle, Alka Arora
DOI: 10.12659/AJCR.953683
Am J Case Rep 2026; 27:e953683
484 801 0

16 Jul 2026 : Case report
Heyde Syndrome Complicated by Pulmonary Embolism Before Transcatheter Aortic Valve Replacement: A Clinical Dilemma Between Bleeding and Thrombosis
Mingying Cao, Lingli Zhang, Ying Ren, Gejun Zhang
DOI: 10.12659/AJCR.953608
Am J Case Rep 2026; 27:e953608
614 858 0

16 Jul 2026 : Case report
Heyde Syndrome Complicated by Pulmonary Embolism Before Transcatheter Aortic Valve Replacement: A Clinical Dilemma Between Bleeding and Thrombosis
Mingying Cao, Lingli Zhang, Ying Ren, Gejun Zhang
DOI: 10.12659/AJCR.953608
Am J Case Rep 2026; 27:e953608
614 858 0

14 Jul 2026 : Case report
Single-Dose Nivolumab as a Trigger of Myocarditis, Myositis, and Myasthenia Gravis Overlap Syndrome With Late Cardiac Death Despite Initial Recovery: A Case Report
Deepika Beereddy, Durga Naga Malleswara Rao Jonnalagadda, Shobha Mandal, Jieyu Zhang
DOI: 10.12659/AJCR.953173
Am J Case Rep 2026; 27:e953173
670 1,184 0

14 Jul 2026 : Case report
Single-Dose Nivolumab as a Trigger of Myocarditis, Myositis, and Myasthenia Gravis Overlap Syndrome With Late Cardiac Death Despite Initial Recovery: A Case Report
Deepika Beereddy, Durga Naga Malleswara Rao Jonnalagadda, Shobha Mandal, Jieyu Zhang
DOI: 10.12659/AJCR.953173
Am J Case Rep 2026; 27:e953173
670 1184 0

13 Jul 2026 : Case report
Coexistence of Multiple Myeloma, Mast Cell Hyperplasia, and Low-Level Myeloid Blastocytosis: A Report of a Rare Case
Meng Yang, Qian Wang, Jian Zhang, Hong Jiang, Hongzhi Xu, Kang Lu, Yujie Jiang
DOI: 10.12659/AJCR.952005
Am J Case Rep 2026; 27:e952005
612 1,164 0

13 Jul 2026 : Case report
Coexistence of Multiple Myeloma, Mast Cell Hyperplasia, and Low-Level Myeloid Blastocytosis: A Report of a Rare Case
Meng Yang, Qian Wang, Jian Zhang, Hong Jiang, Hongzhi Xu, Kang Lu, Yujie Jiang
DOI: 10.12659/AJCR.952005
Am J Case Rep 2026; 27:e952005
612 1164 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953543
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.954216
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.954932
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.954146
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