21 January 2010
Am J Case Rep 2010; 11:35-38 :: ID: 878335
Background: Alveolar soft part sarcoma (ASPS) forms a rare group of sarcomas. ASPS is characterized by a relatively indolent clinical course, but the prognosis is eventually poor. In ophthalmic literature there is only a single case report on ASPS metastasis to the choroid. The aim of this report was to describe another patient with choroidal metastasis of ASPS.
Case Report: A 39-year-old woman was referred to the Clinic of Ophthalmology in Krakow, Poland. On examination in February 2009, a gray-yellow tumor located inferiorly in the left eye 6 mm from the edge of the optic disc was diagnosed. On B-scan ultrasound, the tumor base measured 14.7×15.6 mm and its apical thickness was 6.9–7.3 mm. MRI showed a tumor measuring 7×14×13 mm with elevated intensity on T1- and T2-weighted scans. In 1998 this patient had had surgical resection of a tumor in the left thigh. Histopathological examination revealed ASPS. In 2005, distant metastases to the lung were diagnosed and the patient underwent VAI chemotherapy. Because of poor response to chemotherapy, enucleation was recommended. The patient did not agree and I-125 brachytherapy was performed. Insufficient regression of the tumor associated with secondary exudative retinal detachment prompted the patient to decide to have the blind eye removed. The uneventful surgery took place in July 2009. Histopathology, PAS staining, and the immunohistochemical profile allowed us to diagnose ASPS metastasis to the choroid.
Conclusions: In very rare instances, the choroid may be the location of atypical metastases. ASPS metastasizes to the eye extremely rarely.
Keywords: alveolar soft-part sarcoma, intraocular tumor, Uvea, Choroid, metastasis
30 November 2022 : Case reportSevere COVID-19 in 2 Kidney Transplant Patients in Gabon
Am J Case Rep In Press; DOI: 10.12659/AJCR.938003
23 November 2022 : Case reportMepolizumab as a Potential Protective Factor of COVID-19 Mortality: A Case Report of Chronic Bronchitis and...
Am J Case Rep In Press; DOI: 10.12659/AJCR.938450
01 November 2022 : Case reportCentral Retinal Vein Occlusion After Discontinuation of Rivaroxaban Therapy in a Young Patient with COVID-1...
Am J Case Rep 2022; 23:e937739
02 Dec 2022 : Case reportA 54-Year-Old Woman with Papillary Thyroid Carcinoma Associated with Secondary Amyloid Goiter and Thyroid L...
Am J Case Rep In Press; DOI: 10.12659/AJCR.938156
02 Dec 2022 : Case reportA 14-Year-Old Saudi Boy with Gynecomastia, Cushing Syndrome, Large-Cell Calcifying Sertoli Cell Tumor of th...
Am J Case Rep In Press; DOI: 10.12659/AJCR.937404
01 Dec 2022 : Case reportUreterolithiasis in Human Immunodeficiency Virus (HIV) Patients Treated with Single-Use Ureteroscope: A Cas...
Am J Case Rep In Press; DOI: 10.12659/AJCR.938608
Most Viewed Current Articles
13 Jul 2022 : Case reportWhistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound
Am J Case Rep 2022; 23:e936441
23 Feb 2022 : Case reportPenile Necrosis Associated with Local Intravenous Injection of Cocaine
Am J Case Rep 2022; 23:e935250
06 Dec 2021 : Case reportLipedema Can Be Treated Non-Surgically: A Report of 5 Cases
Am J Case Rep 2021; 22:e934406