18 May 2026
: Case report
[In Press] Vacuum Scaling Drainage in the Treatment of Infected Elbow Charcot Neuroarthropathy: A Case Report and Literature Review
Challenging differential diagnosis, Unusual setting of medical care, Rare disease
Hongyuan Yang1AEFDOI: 10.12659/AJCR.952838
Am J Case Rep In Press; DOI: 10.12659/AJCR.952838
Available online: 2026-05-18, In Press, Corrected Proof
Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule
Abstract
BACKGROUND
Charcot neuroarthropathy (CN) is a rare and easily misdiagnosed neuropathic arthropathy, often secondary to conditions such as syringomyelia and diabetes mellitus. Its clinical course is insidious, making early diagnosis challenging, and the presence of infection further complicates management.
CASE REPORT
This article reports a case of a 48-year-old male patient with elbow CN and secondary infection due to syringomyelia. The patient presented with swelling, erythema, and elevated skin temperature of the left elbow, but without significant pain. Imaging studies revealed elbow dislocation accompanied by extensive bony destruction. Laboratory test results showed a markedly elevated high-sensitivity C-reactive protein level (62.10 mg/L), and bacterial culture identified Staphylococcus aureus infection. After thorough debridement, the patient was treated with vacuum sealing drainage (VSD) combined with intravenous vancomycin for infection control. Following 2 sessions of VSD therapy, the infection was effectively controlled, with good granulation tissue formation, significant reduction in joint swelling, and negative bacterial culture results. At the 6-month follow-up, the elbow remained stable without signs of recurrent infection; the patient reported mild pain and limited range of motion, and definitive reconstructive surgery was deferred due to ongoing risk of infection and patient preference.
CONCLUSIONS
This case suggests that early and thorough debridement combined with VSD is an effective local treatment strategy for CN patients with infection. This approach aids in infection control and promotes wound healing, thereby creating favorable conditions for subsequent functional recovery. VSD, through continuous negative pressure drainage and irrigation, effectively removes necrotic tissue and exudate, improves local microcirculation, and demonstrates good application value in managing CN-related infections.
Keywords: Case Reports; Orthopedics; Staphylococcal Infections; Syringomyelia; Vacuum; Charcot Joint
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