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06 October 2026 : Case report  Poland

[In Press] Carotid Web-Associated Ischemic Stroke in a Young Woman: Diagnostic Pitfalls and Endovascular Management

Unknown etiology, Challenging differential diagnosis, Management of emergency care

Barbara Rosiak1AEF, Adam Dobek ORCID logo1ABDE, Dagmara Wilmańska ORCID logo23BCD, Beata Śliwińska ORCID logo4ABCE, Jacek J. Rożniecki ORCID logo4ADG, Mariusz Stasiołek ORCID logo5ADG, Jarosław Arkadiusz Chrząstek ORCID logo1BCF, Ludomir Stefańczyk1ADG

DOI: 10.12659/AJCR.953876

Am J Case Rep In Press; DOI: 10.12659/AJCR.953876  

Available online: 2026-10-06, In Press, Corrected Proof

Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule

Abstract

BACKGROUND
Carotid web (CaW) is an uncommon intimal variant of fibromuscular dysplasia affecting the internal carotid artery (ICA) and is increasingly recognized as a cause of ischemic stroke in young and middle-aged patients without traditional vascular risk factors. The lesion is a thin, shelf-like fibrointimal projection arising from the carotid bulb that disrupts local hemodynamics and promotes thrombus formation and cerebral embolization. CaW is frequently underdiagnosed because of its subtle imaging appearance and limited clinical awareness.
CASE REPORT
A 40-year-old woman presented with sudden speech disturbances and right-sided weakness. Neurological examination revealed mixed aphasia and mild right hemiparesis (National Institutes of Health Stroke Scale score of 8). Computed tomography angiography (CTA) demonstrated distal branch occlusion of the left middle cerebral artery and an abnormal lesion at the left carotid bulb, suspected to represent CaW. As the intravenous thrombolysis window had elapsed, mechanical thrombectomy was performed, achieving complete reperfusion (modified Thrombolysis in Cerebral Infarction grade 3). Follow-up imaging confirmed left frontoparietal ischemic changes. Extensive diagnostic evaluation excluded other causes of stroke. Persistent carotid stenosis was identified during follow-up, and the patient subsequently underwent carotid angioplasty with stent implantation, restoring normal arterial lumen and cerebral blood flow. The postoperative course was uneventful, and she was discharged in good clinical condition.
CONCLUSIONS
This case highlights the importance of considering CaW in the differential diagnosis of cryptogenic stroke in young patients. Advanced vascular imaging may facilitate timely diagnosis, while appropriate treatment may reduce recurrent cerebrovascular risk. Further studies are needed to define optimal diagnostic and therapeutic strategies for CaW.

Keywords: Carotid Artery Diseases; Stroke; Thrombectomy; Angioplasty

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923