06 October 2026
: Case report
[In Press] Carotid Web-Associated Ischemic Stroke in a Young Woman: Diagnostic Pitfalls and Endovascular Management
Unknown etiology, Challenging differential diagnosis, Management of emergency care
Barbara Rosiak1AEF, Adam DobekDOI: 10.12659/AJCR.953876
Am J Case Rep In Press; DOI: 10.12659/AJCR.953876
Available online: 2026-10-06, In Press, Corrected Proof
Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule
Abstract
BACKGROUND
Carotid web (CaW) is an uncommon intimal variant of fibromuscular dysplasia affecting the internal carotid artery (ICA) and is increasingly recognized as a cause of ischemic stroke in young and middle-aged patients without traditional vascular risk factors. The lesion is a thin, shelf-like fibrointimal projection arising from the carotid bulb that disrupts local hemodynamics and promotes thrombus formation and cerebral embolization. CaW is frequently underdiagnosed because of its subtle imaging appearance and limited clinical awareness.
CASE REPORT
A 40-year-old woman presented with sudden speech disturbances and right-sided weakness. Neurological examination revealed mixed aphasia and mild right hemiparesis (National Institutes of Health Stroke Scale score of 8). Computed tomography angiography (CTA) demonstrated distal branch occlusion of the left middle cerebral artery and an abnormal lesion at the left carotid bulb, suspected to represent CaW. As the intravenous thrombolysis window had elapsed, mechanical thrombectomy was performed, achieving complete reperfusion (modified Thrombolysis in Cerebral Infarction grade 3). Follow-up imaging confirmed left frontoparietal ischemic changes. Extensive diagnostic evaluation excluded other causes of stroke. Persistent carotid stenosis was identified during follow-up, and the patient subsequently underwent carotid angioplasty with stent implantation, restoring normal arterial lumen and cerebral blood flow. The postoperative course was uneventful, and she was discharged in good clinical condition.
CONCLUSIONS
This case highlights the importance of considering CaW in the differential diagnosis of cryptogenic stroke in young patients. Advanced vascular imaging may facilitate timely diagnosis, while appropriate treatment may reduce recurrent cerebrovascular risk. Further studies are needed to define optimal diagnostic and therapeutic strategies for CaW.
Keywords: Carotid Artery Diseases; Stroke; Thrombectomy; Angioplasty
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953701
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953543
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.954216
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.954932
Most Viewed Current Articles
07 Dec 2021 : Case report
28,712,695
DOI :10.12659/AJCR.934347
Am J Case Rep 2021; 22:e934347
06 Dec 2021 : Case report
180,721
DOI :10.12659/AJCR.934406
Am J Case Rep 2021; 22:e934406
21 Jun 2024 : Case report
124,419
DOI :10.12659/AJCR.944371
Am J Case Rep 2024; 25:e944371
08 May 2026 : Case report
95,462
DOI :10.12659/AJCR.952158
Am J Case Rep 2026; 27:e952158






