Unusual clinical course
27 Jan 2026 : Case report 
Discrepant CD3+ TILs in PD-L1–Negative NSCLC: Favorable Outcome in an Elderly Patient Treated With Nivolumab, Ipilimumab, and Chemotherapy
Mataichi Sekiya, Munehide Nakatsugawa, Nobuyuki Koyama 
, Naohiro Kajiwara, Takuya Aoki
DOI: 10.12659/AJCR.951075
Am J Case Rep 2026; 27:e951075
772 1,443 0
27 Jan 2026 : Case report
Discrepant CD3+ TILs in PD-L1–Negative NSCLC: Favorable Outcome in an Elderly Patient Treated With Nivolumab, Ipilimumab, and Chemotherapy
Mataichi Sekiya, Munehide Nakatsugawa, Nobuyuki Koyama , Naohiro Kajiwara, Takuya Aoki
DOI: 10.12659/AJCR.951075
Am J Case Rep 2026; 27:e951075
772 1443 0
26 Jan 2026 : Case report 
A 34-Year-Old Man With a Traumatic Penetrating Injury of the Buttock and Occult Retained Foreign Body Resulting in a High Anal Fistula Managed by Trans-Sphincteric Surgery
Xianbao Liu, Weigan Lin, Minhui Ke, Xianmin Gao, Ruoxuan Shi
DOI: 10.12659/AJCR.950448
Am J Case Rep 2026; 27:e950448
996 2,416 0
26 Jan 2026 : Case report
A 34-Year-Old Man With a Traumatic Penetrating Injury of the Buttock and Occult Retained Foreign Body Resulting in a High Anal Fistula Managed by Trans-Sphincteric Surgery
Xianbao Liu, Weigan Lin, Minhui Ke, Xianmin Gao, Ruoxuan Shi
DOI: 10.12659/AJCR.950448
Am J Case Rep 2026; 27:e950448
996 2416 0
25 Jan 2026 : Case report 
Gastroduodenal Intussusception With Gastric Outlet Obstruction and Periampullary Compression Due to a Gastrointestinal Stromal Tumor in the Stomach
Soumyadip Sain , Vidit A. Dholakia , Suvendu Sekhar Jena , Amitabh Yadav , Samiran Nundy
DOI: 10.12659/AJCR.950627
Am J Case Rep 2026; 27:e950627
1,120 1,886 0
25 Jan 2026 : Case report
Gastroduodenal Intussusception With Gastric Outlet Obstruction and Periampullary Compression Due to a Gastrointestinal Stromal Tumor in the Stomach
Soumyadip Sain , Vidit A. Dholakia , Suvendu Sekhar Jena , Amitabh Yadav , Samiran Nundy
DOI: 10.12659/AJCR.950627
Am J Case Rep 2026; 27:e950627
1120 1886 0
21 Jan 2026 : Case report
Successful Use of Sulbactam–Durlobactam in Treating Carbapenem-Resistant Acinetobacter baumannii Pneumonia and Sepsis After Liver Transplantation: A Case Report
Hao-Feng Xiong , Wan-Ting Zhang , Ying Liu, Fei Hou , Bang Liu , Ting-Ting Cui , Zhi-Ying He , Xin Zhang , Rui Zhao , Li-Ying Sun
DOI: 10.12659/AJCR.949738
Am J Case Rep 2026; 27:e949738
1,157 2,586 0
21 Jan 2026 : Case report
Successful Use of Sulbactam–Durlobactam in Treating Carbapenem-Resistant Acinetobacter baumannii Pneumonia and Sepsis After Liver Transplantation: A Case Report
Hao-Feng Xiong , Wan-Ting Zhang , Ying Liu, Fei Hou , Bang Liu , Ting-Ting Cui , Zhi-Ying He , Xin Zhang , Rui Zhao , Li-Ying Sun
DOI: 10.12659/AJCR.949738
Am J Case Rep 2026; 27:e949738
1157 2586 0
17 Jan 2026 : Case report 
Balancing Bleeding and Ischemic Risk: Dual Antiplatelet Therapy in a 90-Year-Old Man With Myocardial Infarction and Gastrointestinal Bleeding
Ashley Battenberg, Malcolm R. Bell, Mandeep Singh, Allan S. Jaffe, Marysia S. Tweet
DOI: 10.12659/AJCR.949920
Am J Case Rep 2026; 27:e949920
752 3,268 0
17 Jan 2026 : Case report
Balancing Bleeding and Ischemic Risk: Dual Antiplatelet Therapy in a 90-Year-Old Man With Myocardial Infarction and Gastrointestinal Bleeding
Ashley Battenberg, Malcolm R. Bell, Mandeep Singh, Allan S. Jaffe, Marysia S. Tweet
DOI: 10.12659/AJCR.949920
Am J Case Rep 2026; 27:e949920
752 3268 0
20 Jan 2026 : Case report
Clinical Course and Considerations of a Stage G4 Chronic Kidney Disease Patient Who Successfully Initiated Dialysis During Pregnancy and Discontinued It Postpartum
Maki Okamoto, Taisuke Shimizu, Mariko Sato, Sachi Kijima, Sumiko Era, Takatsugu Iwashita, Akihiko Kikuchi, Yasushi Takai , Akito Maeshima, Hajime Hasegawa, Tomonari Ogawa
DOI: 10.12659/AJCR.949709
Am J Case Rep 2026; 27:e949709
955 2,551 0
20 Jan 2026 : Case report
Clinical Course and Considerations of a Stage G4 Chronic Kidney Disease Patient Who Successfully Initiated Dialysis During Pregnancy and Discontinued It Postpartum
Maki Okamoto, Taisuke Shimizu, Mariko Sato, Sachi Kijima, Sumiko Era, Takatsugu Iwashita, Akihiko Kikuchi, Yasushi Takai , Akito Maeshima, Hajime Hasegawa, Tomonari Ogawa
DOI: 10.12659/AJCR.949709
Am J Case Rep 2026; 27:e949709
955 2551 0
16 Jan 2026 : Case report
Rare Case of Second Recurrence of Takotsubo Cardiomyopathy With Variable Ballooning Pattern
Benjamin W. Mancini, Sudhanshu Bhatnagar, Patricia Louis , Julio Andre Hernandez, Brandon R. Peterson
DOI: 10.12659/AJCR.948201
Am J Case Rep 2026; 27:e948201
668 1,447 0
16 Jan 2026 : Case report
Rare Case of Second Recurrence of Takotsubo Cardiomyopathy With Variable Ballooning Pattern
Benjamin W. Mancini, Sudhanshu Bhatnagar, Patricia Louis , Julio Andre Hernandez, Brandon R. Peterson
DOI: 10.12659/AJCR.948201
Am J Case Rep 2026; 27:e948201
668 1447 0
18 Jan 2026 : Case report 
Management of Panniculus Gangrene After Cesarean Hysterectomy for Placenta Accreta: A Case Report
Nadin Alghanaim
DOI: 10.12659/AJCR.949353
Am J Case Rep 2026; 27:e949353
700 1,319 0
18 Jan 2026 : Case report
Management of Panniculus Gangrene After Cesarean Hysterectomy for Placenta Accreta: A Case Report
Nadin Alghanaim
DOI: 10.12659/AJCR.949353
Am J Case Rep 2026; 27:e949353
700 1319 0
15 Jan 2026 : Case report 
Phenotypic Spectrum of Type 2-3 Gaucher Disease: A Case Study in the Balkan Genotype
Paskal Cullufi , Virtut Velmishi , Ermira Dervishi, Sonila Tomori , Gladiola Hoxha, Eda Jazexhiu-Postoli , Entela Basha , Aferdita Kumaraku Tako, Mirela Tabaku
DOI: 10.12659/AJCR.948999
Am J Case Rep 2026; 27:e948999
904 1,674 0
15 Jan 2026 : Case report
Phenotypic Spectrum of Type 2-3 Gaucher Disease: A Case Study in the Balkan Genotype
Paskal Cullufi , Virtut Velmishi , Ermira Dervishi, Sonila Tomori , Gladiola Hoxha, Eda Jazexhiu-Postoli , Entela Basha , Aferdita Kumaraku Tako, Mirela Tabaku
DOI: 10.12659/AJCR.948999
Am J Case Rep 2026; 27:e948999
904 1674 0
12 Jan 2026 : Case report
Atypical Appendicitis Mimicking Gynecological Pathology: A Diagnostic Challenge in a Middle-Aged Woman
Uma Hemant Chourasia
DOI: 10.12659/AJCR.949850
Am J Case Rep 2026; 27:e949850
787 6,416 0
12 Jan 2026 : Case report
Atypical Appendicitis Mimicking Gynecological Pathology: A Diagnostic Challenge in a Middle-Aged Woman
Uma Hemant Chourasia
DOI: 10.12659/AJCR.949850
Am J Case Rep 2026; 27:e949850
787 6416 0
11 Jan 2026 : Case report
Complex Aorto-Spinal Fistula With Multifocal Abscesses in an Immunosuppressed Elderly Man Following Endovascular Aortic Repair
Adam Henderson , Mohamed G. Ibrahim, Mario El Hayek, Margaret E. McKinney, Jesse W. St Clair IV
DOI: 10.12659/AJCR.949903
Am J Case Rep 2026; 27:e949903
1,030 1,436 0
11 Jan 2026 : Case report
Complex Aorto-Spinal Fistula With Multifocal Abscesses in an Immunosuppressed Elderly Man Following Endovascular Aortic Repair
Adam Henderson , Mohamed G. Ibrahim, Mario El Hayek, Margaret E. McKinney, Jesse W. St Clair IV
DOI: 10.12659/AJCR.949903
Am J Case Rep 2026; 27:e949903
1030 1436 0
10 Jan 2026 : Case report 
Prolonged Tardive Dyskinesia Induced by Long-Acting Paliperidone Palmitate in Schizophrenia: A Case Report
Yu-Ming Chen , Shangwen Chang
DOI: 10.12659/AJCR.949867
Am J Case Rep 2026; 27:e949867
1,298 3,621 0
10 Jan 2026 : Case report
Prolonged Tardive Dyskinesia Induced by Long-Acting Paliperidone Palmitate in Schizophrenia: A Case Report
Yu-Ming Chen , Shangwen Chang
DOI: 10.12659/AJCR.949867
Am J Case Rep 2026; 27:e949867
1298 3621 0
10 Jan 2026 : Case report
Persistent SARS-CoV-2 Infection in an Immunocompromised Host Treated Successfully With the Japanese Herbal Medicine, Mao-to: A Case Report
Takayuki Yamada, Shiro Sonoda, Mitsuki Otsuka, Tsuyoshi Shirai, Tomoya Tateishi , Haruhiko Furusawa , Yasunari Miyazaki
DOI: 10.12659/AJCR.950221
Am J Case Rep 2026; 27:e950221
2,217 2,649 0
10 Jan 2026 : Case report
Persistent SARS-CoV-2 Infection in an Immunocompromised Host Treated Successfully With the Japanese Herbal Medicine, Mao-to: A Case Report
Takayuki Yamada, Shiro Sonoda, Mitsuki Otsuka, Tsuyoshi Shirai, Tomoya Tateishi , Haruhiko Furusawa , Yasunari Miyazaki
DOI: 10.12659/AJCR.950221
Am J Case Rep 2026; 27:e950221
2217 2649 0
09 Jan 2026 : Case report 
Effects of Individualized Forearm Isometric Exercise on Blood Flow Volume After Arteriovenous Fistula Surgery: A Case Series
Yose Waluyo , Umar Usman, Muhammad Syairozi Hidayat
DOI: 10.12659/AJCR.949334
Am J Case Rep 2026; 27:e949334
858 1,471 0
09 Jan 2026 : Case report
Effects of Individualized Forearm Isometric Exercise on Blood Flow Volume After Arteriovenous Fistula Surgery: A Case Series
Yose Waluyo , Umar Usman, Muhammad Syairozi Hidayat
DOI: 10.12659/AJCR.949334
Am J Case Rep 2026; 27:e949334
858 1471 0
03 Dec 2025 : Case report
Atypical Presentation of Boerhaave Syndrome with Left Shoulder Pain as the Initial Manifestation: A Case Report
Wei-Hsi Chang, Wen-Fan Chen, Mao-Hsien Chang
DOI: 10.12659/AJCR.949952
Am J Case Rep 2025; 26:e949952
839 1,478 0
03 Dec 2025 : Case report
Atypical Presentation of Boerhaave Syndrome with Left Shoulder Pain as the Initial Manifestation: A Case Report
Wei-Hsi Chang, Wen-Fan Chen, Mao-Hsien Chang
DOI: 10.12659/AJCR.949952
Am J Case Rep 2025; 26:e949952
839 1478 0
03 Jan 2026 : Case report
Intraocular Lens Opacification in a Patient With Gyrate Atrophy With a Subluxated Intraocular Lens
Yazeed A. Alferayan, Sami T. Hameed, Azza M.Y. Maktabi, Faisal F. Alsaif
DOI: 10.12659/AJCR.950243
Am J Case Rep 2026; 27:e950243
616 1,849 0
03 Jan 2026 : Case report
Intraocular Lens Opacification in a Patient With Gyrate Atrophy With a Subluxated Intraocular Lens
Yazeed A. Alferayan, Sami T. Hameed, Azza M.Y. Maktabi, Faisal F. Alsaif
DOI: 10.12659/AJCR.950243
Am J Case Rep 2026; 27:e950243
616 1849 0
05 Jan 2026 : Case report 
A 67-Year-Old Man With Hypertension Presenting With Spontaneous Rupture of a Large Splenic Artery Aneurysm Associated With Thrombus
Rakia Siala, Mohamed Ali Mseddi , Chaima Yakoubi , Alia Zehani, Hajer Hassine, Meriem Hsairi , Rami Guizani , Hela Kchir , Karim Sassi, Mohamed Ben Slima
DOI: 10.12659/AJCR.950099
Am J Case Rep 2026; 27:e950099
945 1,589 0
05 Jan 2026 : Case report
A 67-Year-Old Man With Hypertension Presenting With Spontaneous Rupture of a Large Splenic Artery Aneurysm Associated With Thrombus
Rakia Siala, Mohamed Ali Mseddi , Chaima Yakoubi , Alia Zehani, Hajer Hassine, Meriem Hsairi , Rami Guizani , Hela Kchir , Karim Sassi, Mohamed Ben Slima
DOI: 10.12659/AJCR.950099
Am J Case Rep 2026; 27:e950099
945 1589 0
02 Jan 2026 : Case report
Multidisciplinary Management and Anesthesia Considerations for Diabetic Ketoacidosis With Hypertriglyceridemic Acute Pancreatitis in Pregnancy: A Case Report
Peiting Liu, Tao Li, Suquan Yu, Fan Liu, Lanji Huang
DOI: 10.12659/AJCR.949837
Am J Case Rep 2026; 27:e949837
1,351 108 0
02 Jan 2026 : Case report
Multidisciplinary Management and Anesthesia Considerations for Diabetic Ketoacidosis With Hypertriglyceridemic Acute Pancreatitis in Pregnancy: A Case Report
Peiting Liu, Tao Li, Suquan Yu, Fan Liu, Lanji Huang
DOI: 10.12659/AJCR.949837
Am J Case Rep 2026; 27:e949837
1351 108 0
27 Nov 2025 : Case report 
Gastric Bipartition with Functional Duodenum Exclusion (GBp-FDE) as a Possible Surgical Conversion of Sleeve Gastrectomy in Patients with De Novo GERD and Obesity Recidivism: Preliminary Results of a Case Series
Victor Ramos Mussa Dib , Carlos Augusto Scussel Madalosso , Paulo Reis Rizzo Esselin De Melo , Almino Cardoso Ramos , Luiz Alfredo Vieira D'Almeida , Luciano Antozzi , José María Balibrea del Castillo , Patrick Noel , Manoel Passos Galvão Neto , Sonja Chiappetta , Fernando de Barros , André Teixeira , Elinton Adami Chaim , Ricardo Zorron , Eudes Paiva de Godoy , Caio Gustavo Gaspar de Aquino , Giorgio Alfredo Pedroso Baretta , Diogo Swain Kfouri , Hiroji Okano Júnior , Nilton Tokio Kawahara , Augusto Cláudio de Almeida Tinoco , Nicholas Tavares Kruel , Joe Joaquim Waltrick Junior, Carlos Frota Dillenburg , Félix Antônio Insaurriaga Dos Santos , Rafael Antoniazzi Abaid , Carlos Eduardo Alves Da Costa , Gabriela Trentin Scortegagna , Geovana F. Silva , Halit Eren Taskin , Ricardo M. Nassar , Laurent Abram Layani , Daniel Oscar Caiña , Manuel Aceves Avalos , Jorge Bravo Lópes , José Sergio Verboonen Sotelo , Ramon Vilallonga Puy , Christine Karolina Stier , Carlos Eduardo Domene , Paula Volpe , Amador García Ruiz de Gordejuela , Luis Poggi , Antônio Torres , Miguel Ángel Carbajo , Italo Braghetto , Rui Ribeiro , Chetan Parmar
DOI: 10.12659/AJCR.950798
Am J Case Rep 2025; 26:e950798
1,178 2,263 0
27 Nov 2025 : Case report
Gastric Bipartition with Functional Duodenum Exclusion (GBp-FDE) as a Possible Surgical Conversion of Sleeve Gastrectomy in Patients with De Novo GERD and Obesity Recidivism: Preliminary Results of a Case Series
Victor Ramos Mussa Dib , Carlos Augusto Scussel Madalosso , Paulo Reis Rizzo Esselin De Melo , Almino Cardoso Ramos , Luiz Alfredo Vieira D'Almeida , Luciano Antozzi , José María Balibrea del Castillo , Patrick Noel , Manoel Passos Galvão Neto , Sonja Chiappetta , Fernando de Barros , André Teixeira , Elinton Adami Chaim , Ricardo Zorron , Eudes Paiva de Godoy , Caio Gustavo Gaspar de Aquino , Giorgio Alfredo Pedroso Baretta , Diogo Swain Kfouri , Hiroji Okano Júnior , Nilton Tokio Kawahara , Augusto Cláudio de Almeida Tinoco , Nicholas Tavares Kruel , Joe Joaquim Waltrick Junior, Carlos Frota Dillenburg , Félix Antônio Insaurriaga Dos Santos , Rafael Antoniazzi Abaid , Carlos Eduardo Alves Da Costa , Gabriela Trentin Scortegagna , Geovana F. Silva , Halit Eren Taskin , Ricardo M. Nassar , Laurent Abram Layani , Daniel Oscar Caiña , Manuel Aceves Avalos , Jorge Bravo Lópes , José Sergio Verboonen Sotelo , Ramon Vilallonga Puy , Christine Karolina Stier , Carlos Eduardo Domene , Paula Volpe , Amador García Ruiz de Gordejuela , Luis Poggi , Antônio Torres , Miguel Ángel Carbajo , Italo Braghetto , Rui Ribeiro , Chetan Parmar
DOI: 10.12659/AJCR.950798
Am J Case Rep 2025; 26:e950798
1178 2263 0
29 Dec 2025 : Case report
Rapidly Progressive Disseminated Bacillus Calmette-Guérin Infection (BCGitis) in a 3-Month-Old Infant Without Immunodeficiency: A Case Report
Nathalya Queiroz Perillo, Taynara Heliodoro , Leandro Azevedo De Camargo, Melissa Ameloti Gomes Avelino, Fayez Bahmad Jr.
DOI: 10.12659/AJCR.949742
Am J Case Rep 2025; 26:e949742
773 1,886 0
29 Dec 2025 : Case report
Rapidly Progressive Disseminated Bacillus Calmette-Guérin Infection (BCGitis) in a 3-Month-Old Infant Without Immunodeficiency: A Case Report
Nathalya Queiroz Perillo, Taynara Heliodoro , Leandro Azevedo De Camargo, Melissa Ameloti Gomes Avelino, Fayez Bahmad Jr.
DOI: 10.12659/AJCR.949742
Am J Case Rep 2025; 26:e949742
773 1886 0
26 Dec 2025 : Case report 
Isolated Neck Pain as an Atypical Manifestation of Type A Acute Aortic Dissection: A Case Report
Łukasz Turek , Jacek Kurzawski , Łukasz Zandecki , Małgorzata Zachura , Agata Kundera-Mądro , Marianna Janion
DOI: 10.12659/AJCR.949758
Am J Case Rep 2025; 26:e949758
902 2,189 0
26 Dec 2025 : Case report
Isolated Neck Pain as an Atypical Manifestation of Type A Acute Aortic Dissection: A Case Report
Łukasz Turek , Jacek Kurzawski , Łukasz Zandecki , Małgorzata Zachura , Agata Kundera-Mądro , Marianna Janion
DOI: 10.12659/AJCR.949758
Am J Case Rep 2025; 26:e949758
902 2189 0
25 Dec 2025 : Case report 
The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia
Moath Fateh , Tariq Albweitel, Ahmad Odeh, Sarah Ghaith
DOI: 10.12659/AJCR.950626
Am J Case Rep 2025; 26:e950626
954 3,536 0
25 Dec 2025 : Case report
The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia
Moath Fateh , Tariq Albweitel, Ahmad Odeh, Sarah Ghaith
DOI: 10.12659/AJCR.950626
Am J Case Rep 2025; 26:e950626
954 3536 0
20 Dec 2025 : Case report 
Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment
Ugo Françoise , Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle , Paul Le Turnier
DOI: 10.12659/AJCR.945090
Am J Case Rep 2025; 26:e945090
1,222 2,573 0
20 Dec 2025 : Case report
Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment
Ugo Françoise , Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle , Paul Le Turnier
DOI: 10.12659/AJCR.945090
Am J Case Rep 2025; 26:e945090
1222 2573 0
19 Dec 2025 : Case report
Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis
Meghan Stevenson, Naveed Younis
DOI: 10.12659/AJCR.950208
Am J Case Rep 2025; 26:e950208
919 1,690 0
19 Dec 2025 : Case report
Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis
Meghan Stevenson, Naveed Younis
DOI: 10.12659/AJCR.950208
Am J Case Rep 2025; 26:e950208
919 1690 0
21 Dec 2025 : Case report
Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer
Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye
DOI: 10.12659/AJCR.947770
Am J Case Rep 2025; 26:e947770
1,105 2,402 0
21 Dec 2025 : Case report
Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer
Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye
DOI: 10.12659/AJCR.947770
Am J Case Rep 2025; 26:e947770
1105 2402 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.954777
Case report 
Am J Case Rep In Press; DOI: 10.12659/AJCR.953433
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Am J Case Rep In Press; DOI: 10.12659/AJCR.953495
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953909
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