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Unusual clinical course

#949019

18 Nov 2025 : Case report  Switzerland

Exploring Maralixibat for Treatment-Resistant Pruritus in Intrahepatic Cholestasis of Pregnancy and Primary Biliary Cholangitis: A Case Report

Lara Alexandra Bersuch ORCID logo, Andrea De Gottardi ORCID logo

DOI: 10.12659/AJCR.949019

Am J Case Rep 2025; 26:e949019

995 2,341 0

#949019

18 Nov 2025 : Case report  Switzerland

Exploring Maralixibat for Treatment-Resistant Pruritus in Intrahepatic Cholestasis of Pregnancy and Primary Biliary Cholangitis: A Case Report

Lara Alexandra Bersuch ORCID logo, Andrea De Gottardi ORCID logo

DOI: 10.12659/AJCR.949019

Am J Case Rep 2025; 26:e949019

995 2341 0

#948856

17 Nov 2025 : Case report  Israel

Sclerosing Cholangitis and Multiple Liver Abscesses in a Patient with Thymoma, Myasthenia Gravis, and Immune Deficiency (Good’s Syndrome)

Shaul Yaari, Joshua Stokar ORCID logo, Yehonatan Bar Moshe, Nurith Hiller, Elena Zuckerman, Samuel N. Heyman

DOI: 10.12659/AJCR.948856

Am J Case Rep 2025; 26:e948856

711 1,130 0

#948856

17 Nov 2025 : Case report  Israel

Sclerosing Cholangitis and Multiple Liver Abscesses in a Patient with Thymoma, Myasthenia Gravis, and Immune Deficiency (Good’s Syndrome)

Shaul Yaari, Joshua Stokar ORCID logo, Yehonatan Bar Moshe, Nurith Hiller, Elena Zuckerman, Samuel N. Heyman

DOI: 10.12659/AJCR.948856

Am J Case Rep 2025; 26:e948856

711 1130 0

#949210

26 Nov 2025 : Case report  China

Pharmacological Intervention for Refractory Biofilm Infection After Hemipelvic Replacement Surgery: Multidisciplinary Management of a Case of Giant Cell Tumor of Bone

Liling Huang, Linyu Wang ORCID logo, Hao Nong, Bin Liu, Yan Li

DOI: 10.12659/AJCR.949210

Am J Case Rep 2025; 26:e949210

803 1,345 0

#949210

26 Nov 2025 : Case report  China

Pharmacological Intervention for Refractory Biofilm Infection After Hemipelvic Replacement Surgery: Multidisciplinary Management of a Case of Giant Cell Tumor of Bone

Liling Huang, Linyu Wang ORCID logo, Hao Nong, Bin Liu, Yan Li

DOI: 10.12659/AJCR.949210

Am J Case Rep 2025; 26:e949210

803 1345 0

#950362

11 Dec 2025 : Case report  China

Novel Sequential Therapy with Obinutuzumab and Telitacicept in Severe Lupus Nephritis with Glucocorticoid-Induced Avascular Necrosis (AVN) of the Femoral Head: A Case Report

Yu Zhang ORCID logo, Liqi Huang, Na Li, Xuelin Zeng ORCID logo, Zhihua Zheng, Xiaohua Wang, Yiqing Zhang, Chun Tang

DOI: 10.12659/AJCR.950362

Am J Case Rep 2025; 26:e950362

1,038 1,496 0

#950362

11 Dec 2025 : Case report  China

Novel Sequential Therapy with Obinutuzumab and Telitacicept in Severe Lupus Nephritis with Glucocorticoid-Induced Avascular Necrosis (AVN) of the Femoral Head: A Case Report

Yu Zhang ORCID logo, Liqi Huang, Na Li, Xuelin Zeng ORCID logo, Zhihua Zheng, Xiaohua Wang, Yiqing Zhang, Chun Tang

DOI: 10.12659/AJCR.950362

Am J Case Rep 2025; 26:e950362

1038 1496 0

#948143

24 Nov 2025 : Case report  China

Hypophysitis Induced by Tislelizumab: A Case Report of Somnolence and Delirium with Elevated Eosinophils

Fenglin Hu, Ni Lou, Guolin Wu

DOI: 10.12659/AJCR.948143

Am J Case Rep 2025; 26:e948143

889 1,237 0

#948143

24 Nov 2025 : Case report  China

Hypophysitis Induced by Tislelizumab: A Case Report of Somnolence and Delirium with Elevated Eosinophils

Fenglin Hu, Ni Lou, Guolin Wu

DOI: 10.12659/AJCR.948143

Am J Case Rep 2025; 26:e948143

889 1237 0

#949884

20 Nov 2025 : Case report  China

Ocular Involvement in Post-Transplantation Lymphoproliferative Disorder: A Rare Case with Rituximab Hypersensitivity

Jing-yi Liu ORCID logo, Wan-Ting Zhang, Kang Wang, Ying Liu, Lin Wei, Wei Qu, Zhi-Gui Zeng, Zhi-Jun Zhu, Li-Ying Sun

DOI: 10.12659/AJCR.949884

Am J Case Rep 2025; 26:e949884

808 1,241 0

#949884

20 Nov 2025 : Case report  China

Ocular Involvement in Post-Transplantation Lymphoproliferative Disorder: A Rare Case with Rituximab Hypersensitivity

Jing-yi Liu ORCID logo, Wan-Ting Zhang, Kang Wang, Ying Liu, Lin Wei, Wei Qu, Zhi-Gui Zeng, Zhi-Jun Zhu, Li-Ying Sun

DOI: 10.12659/AJCR.949884

Am J Case Rep 2025; 26:e949884

808 1241 0

#950134

19 Nov 2025 : Case report  China

Multifocal Mesenteric Desmoid-Type Fibromatosis After Liver Transplantation: A Case Report

Ning Zhang, Yuqing Du, Meng Wang, Ruifang Xu, Li Li, Ying Feng, Zhanxiong Yi, Enhui He

DOI: 10.12659/AJCR.950134

Am J Case Rep 2025; 26:e950134

613 1,153 0

#950134

19 Nov 2025 : Case report  China

Multifocal Mesenteric Desmoid-Type Fibromatosis After Liver Transplantation: A Case Report

Ning Zhang, Yuqing Du, Meng Wang, Ruifang Xu, Li Li, Ying Feng, Zhanxiong Yi, Enhui He

DOI: 10.12659/AJCR.950134

Am J Case Rep 2025; 26:e950134

613 1153 0

#950013

10 Nov 2025 : Case report  USA

Atrio-Ventricular Nodal Block Associated with Methamphetamine Use

Nicholas L. Vitagliano, Tyler Ky, John M. Kennedy

DOI: 10.12659/AJCR.950013

Am J Case Rep 2025; 26:e950013

772 1,000 0

#950013

10 Nov 2025 : Case report  USA

Atrio-Ventricular Nodal Block Associated with Methamphetamine Use

Nicholas L. Vitagliano, Tyler Ky, John M. Kennedy

DOI: 10.12659/AJCR.950013

Am J Case Rep 2025; 26:e950013

772 1000 0

#949777

09 Nov 2025 : Case report  Canada

Use of Neoadjuvant Immunotherapy in Malignant Peritoneal Mesothelioma as a Bridge to Surgical Intervention: A Case Report

Sohayb Faleh, Tanya Odisho, Florence Lebel-Guay, Mikaël L. Soucisse ORCID logo, Jose Ferreira, Sara V. Soldera ORCID logo, Lucas Sideris

DOI: 10.12659/AJCR.949777

Am J Case Rep 2025; 26:e949777

834 1,697 0

#949777

09 Nov 2025 : Case report  Canada

Use of Neoadjuvant Immunotherapy in Malignant Peritoneal Mesothelioma as a Bridge to Surgical Intervention: A Case Report

Sohayb Faleh, Tanya Odisho, Florence Lebel-Guay, Mikaël L. Soucisse ORCID logo, Jose Ferreira, Sara V. Soldera ORCID logo, Lucas Sideris

DOI: 10.12659/AJCR.949777

Am J Case Rep 2025; 26:e949777

834 1697 0

#950091

11 Nov 2025 : Case report  Saudi Arabia

Myocardial Ischemia Secondary to Anomalous Origin of Left Anterior Descending Coronary Artery: A Case Report and Literature Review

Osama A. Abdulrahman, Marah M. Alsulami, Shumukh B. Altuwairgi, Mohammad F. Babgi, Nabil A. Alrashidi, Ehab Kasem, Mohammed H. Miny, Elnazeer O. Ahmed

DOI: 10.12659/AJCR.950091

Am J Case Rep 2025; 26:e950091

832 1,350 0

#950091

11 Nov 2025 : Case report  Saudi Arabia

Myocardial Ischemia Secondary to Anomalous Origin of Left Anterior Descending Coronary Artery: A Case Report and Literature Review

Osama A. Abdulrahman, Marah M. Alsulami, Shumukh B. Altuwairgi, Mohammad F. Babgi, Nabil A. Alrashidi, Ehab Kasem, Mohammed H. Miny, Elnazeer O. Ahmed

DOI: 10.12659/AJCR.950091

Am J Case Rep 2025; 26:e950091

832 1350 0

#949362

08 Nov 2025 : Case report  Switzerland

Hypnosis as a Non-Pharmacologic Adjunct in Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for Essential Tremor: A Case Report

Alessandro Pascucci ORCID logo, Alexandre Jeleff ORCID logo, Marie-José Lahoud ORCID logo, Luigi Francesco Saccaro ORCID logo, Shahan Momjian, Rosa Tesoro

DOI: 10.12659/AJCR.949362

Am J Case Rep 2025; 26:e949362

860 1,716 0

#949362

08 Nov 2025 : Case report  Switzerland

Hypnosis as a Non-Pharmacologic Adjunct in Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for Essential Tremor: A Case Report

Alessandro Pascucci ORCID logo, Alexandre Jeleff ORCID logo, Marie-José Lahoud ORCID logo, Luigi Francesco Saccaro ORCID logo, Shahan Momjian, Rosa Tesoro

DOI: 10.12659/AJCR.949362

Am J Case Rep 2025; 26:e949362

860 1716 0

#950114

04 Nov 2025 : Case report  Brazil

Laparoscopic Gastrojejunopexy in Giant and Recurrent Hiatal Hernia Management: A Case Report

Victor Ramos Mussa Dib ORCID logo, Luis Poggi ORCID logo, Carlos Augusto Scussel Madalosso ORCID logo, Paulo Reis Rizzo Esselin De Melo ORCID logo, Almino Cardoso Ramos ORCID logo, Luciano Antozzi ORCID logo, Antelmo Sasso Fin ORCID logo, Rui Ribeiro ORCID logo, Hiroji Okano Júnior ORCID logo, Paula Volpe ORCID logo, Carlos Eduardo Domene ORCID logo, Italo Braghetto ORCID logo

DOI: 10.12659/AJCR.950114

Am J Case Rep 2025; 26:e950114

967 65 0

#950114

04 Nov 2025 : Case report  Brazil

Laparoscopic Gastrojejunopexy in Giant and Recurrent Hiatal Hernia Management: A Case Report

Victor Ramos Mussa Dib ORCID logo, Luis Poggi ORCID logo, Carlos Augusto Scussel Madalosso ORCID logo, Paulo Reis Rizzo Esselin De Melo ORCID logo, Almino Cardoso Ramos ORCID logo, Luciano Antozzi ORCID logo, Antelmo Sasso Fin ORCID logo, Rui Ribeiro ORCID logo, Hiroji Okano Júnior ORCID logo, Paula Volpe ORCID logo, Carlos Eduardo Domene ORCID logo, Italo Braghetto ORCID logo

DOI: 10.12659/AJCR.950114

Am J Case Rep 2025; 26:e950114

967 65 0

#949098

02 Nov 2025 : Case report  Switzerland

Comprehensive Management of Obstetric Rectal Buttonhole Tears: Insights From a Case Report and Literature Analysis

Georgia Ilia ORCID logo, Barbara Blöchlinger-Wegmann, Theodoros Theodoridis, Sophia Kudelka, Dimitrios Chronas

DOI: 10.12659/AJCR.949098

Am J Case Rep 2025; 26:e949098

715 2,225 0

#949098

02 Nov 2025 : Case report  Switzerland

Comprehensive Management of Obstetric Rectal Buttonhole Tears: Insights From a Case Report and Literature Analysis

Georgia Ilia ORCID logo, Barbara Blöchlinger-Wegmann, Theodoros Theodoridis, Sophia Kudelka, Dimitrios Chronas

DOI: 10.12659/AJCR.949098

Am J Case Rep 2025; 26:e949098

715 2225 0

#948966

07 Nov 2025 : Case report  Vietnam

Navigating Diagnostic Challenges in Pseudoachalasia: A Case Study of Esophagogastric Junction Adenocarcinoma

Thanh Huu Nguyen ORCID logo, Thang Quoc Le ORCID logo, Muoi Xuan Nguyen, Ha Van Quoc, Thinh Van Quoc Tran ORCID logo, Pham Thi Thu Huong, Ta Que Phuong, Bui Chi Nam, Pham Duc Huan

DOI: 10.12659/AJCR.948966

Am J Case Rep 2025; 26:e948966

685 1,672 0

#948966

07 Nov 2025 : Case report  Vietnam

Navigating Diagnostic Challenges in Pseudoachalasia: A Case Study of Esophagogastric Junction Adenocarcinoma

Thanh Huu Nguyen ORCID logo, Thang Quoc Le ORCID logo, Muoi Xuan Nguyen, Ha Van Quoc, Thinh Van Quoc Tran ORCID logo, Pham Thi Thu Huong, Ta Que Phuong, Bui Chi Nam, Pham Duc Huan

DOI: 10.12659/AJCR.948966

Am J Case Rep 2025; 26:e948966

685 1672 0

#950345

28 Oct 2025 : Case report  USA

Anorexia Nervosa Complicated by Acute Pericarditis, Spontaneous Pneumomediastinum, and Liver Injury: A Case Report

Obaid Imtiyazul Haque ORCID logo, Obaid Ur Rehman ORCID logo, Urwah Ahmad, Mahyar Toofantabrizi

DOI: 10.12659/AJCR.950345

Am J Case Rep 2025; 26:e950345

664 1,922 0

#950345

28 Oct 2025 : Case report  USA

Anorexia Nervosa Complicated by Acute Pericarditis, Spontaneous Pneumomediastinum, and Liver Injury: A Case Report

Obaid Imtiyazul Haque ORCID logo, Obaid Ur Rehman ORCID logo, Urwah Ahmad, Mahyar Toofantabrizi

DOI: 10.12659/AJCR.950345

Am J Case Rep 2025; 26:e950345

664 1922 0

#947857

01 Nov 2025 : Case report  Oman

Unexpected Pneumomediastinum in Crohn’s Disease: Implications and Case Analysis

Jawahar Al Noumani ORCID logo, Wijdan Abdullah Al Balushi, Zaiyana Abdulaziz Ambusaidi, Jawahir Lal

DOI: 10.12659/AJCR.947857

Am J Case Rep 2025; 26:e947857

524 990 0

#947857

01 Nov 2025 : Case report  Oman

Unexpected Pneumomediastinum in Crohn’s Disease: Implications and Case Analysis

Jawahar Al Noumani ORCID logo, Wijdan Abdullah Al Balushi, Zaiyana Abdulaziz Ambusaidi, Jawahir Lal

DOI: 10.12659/AJCR.947857

Am J Case Rep 2025; 26:e947857

524 990 0

#950003

03 Nov 2025 : Case report  China

Right Ventricular Volume Overload Mimicking Pulmonary Embolism: A Case of Intraoperative Fluid Absorption-Induced Ventricular Interdependence

Chunliang Wang ORCID logo, Yuzhu Fan, Juan Wang, Yu Chen, Ying Cui, Hongzhao Zhang

DOI: 10.12659/AJCR.950003

Am J Case Rep 2025; 26:e950003

528 2,444 0

#950003

03 Nov 2025 : Case report  China

Right Ventricular Volume Overload Mimicking Pulmonary Embolism: A Case of Intraoperative Fluid Absorption-Induced Ventricular Interdependence

Chunliang Wang ORCID logo, Yuzhu Fan, Juan Wang, Yu Chen, Ying Cui, Hongzhao Zhang

DOI: 10.12659/AJCR.950003

Am J Case Rep 2025; 26:e950003

528 2444 0

#949108

31 Oct 2025 : Case report  China

Dual Radial and Femoral Arterial Access for Mechanical Thrombectomy in Acute Middle Cerebral Artery Occlusion: A Case Report

Huansong Wang ORCID logo, Lingling Zhang ORCID logo, Kai Wang, Yong Guan, Guiying Zhang

DOI: 10.12659/AJCR.949108

Am J Case Rep 2025; 26:e949108

464 1,369 0

#949108

31 Oct 2025 : Case report  China

Dual Radial and Femoral Arterial Access for Mechanical Thrombectomy in Acute Middle Cerebral Artery Occlusion: A Case Report

Huansong Wang ORCID logo, Lingling Zhang ORCID logo, Kai Wang, Yong Guan, Guiying Zhang

DOI: 10.12659/AJCR.949108

Am J Case Rep 2025; 26:e949108

464 1369 0

#949779

27 Oct 2025 : Case report  Japan

Simultaneous Bilateral Methicillin-Resistant Staphylococcus aureus Infection After Total Knee Arthroplasty Successfully Treated with Continuous Local Antibiotic Perfusion: A Case Report

Kohei Motono, Tomoyuki Matsumoto, Keisuke Oe, Masanori Tsubosaka, Naoki Nakano, Tomoaki Fukui, Yohei Kumabe, Ryosuke Kuroda

DOI: 10.12659/AJCR.949779

Am J Case Rep 2025; 26:e949779

881 1,575 0

#949779

27 Oct 2025 : Case report  Japan

Simultaneous Bilateral Methicillin-Resistant Staphylococcus aureus Infection After Total Knee Arthroplasty Successfully Treated with Continuous Local Antibiotic Perfusion: A Case Report

Kohei Motono, Tomoyuki Matsumoto, Keisuke Oe, Masanori Tsubosaka, Naoki Nakano, Tomoaki Fukui, Yohei Kumabe, Ryosuke Kuroda

DOI: 10.12659/AJCR.949779

Am J Case Rep 2025; 26:e949779

881 1575 0

#947024

25 Oct 2025 : Case report  Brazil

Intraosseous Cellular Schwannoma in the Infraorbital Region: A Rare Case

Edmundo Luis Rodrigues Pereira ORCID logo, Rebeca Viera Costa, Jeovanna Brito de Moraes ORCID logo, Alessandra Arnaud Moreira, Thayna Silva do Carmo Tavares ORCID logo, Fabricio Passador-Santos ORCID logo, Lucas Rodrigues Pinheiro ORCID logo, Sérgio de Melo Alves Júnior ORCID logo, João de Jesus Viana Pinheiro ORCID logo

DOI: 10.12659/AJCR.947024

Am J Case Rep 2025; 26:e947024

521 1,182 0

#947024

25 Oct 2025 : Case report  Brazil

Intraosseous Cellular Schwannoma in the Infraorbital Region: A Rare Case

Edmundo Luis Rodrigues Pereira ORCID logo, Rebeca Viera Costa, Jeovanna Brito de Moraes ORCID logo, Alessandra Arnaud Moreira, Thayna Silva do Carmo Tavares ORCID logo, Fabricio Passador-Santos ORCID logo, Lucas Rodrigues Pinheiro ORCID logo, Sérgio de Melo Alves Júnior ORCID logo, João de Jesus Viana Pinheiro ORCID logo

DOI: 10.12659/AJCR.947024

Am J Case Rep 2025; 26:e947024

521 1182 0

#949828

24 Oct 2025 : Case report  USA

Medical Management of an Infusion Site Extravasation Injury After Peripheral Intravenous Infusion of Ado-Trastuzumab Emtansine in a 38-Year-Old Woman With Breast Cancer: A Case Report

Eleni M. Gamvroulas, Patricia Jeppson, Mei Wei ORCID logo

DOI: 10.12659/AJCR.949828

Am J Case Rep 2025; 26:e949828

679 1,785 0

#949828

24 Oct 2025 : Case report  USA

Medical Management of an Infusion Site Extravasation Injury After Peripheral Intravenous Infusion of Ado-Trastuzumab Emtansine in a 38-Year-Old Woman With Breast Cancer: A Case Report

Eleni M. Gamvroulas, Patricia Jeppson, Mei Wei ORCID logo

DOI: 10.12659/AJCR.949828

Am J Case Rep 2025; 26:e949828

679 1785 0

#948728

08 Oct 2025 : Case report  Ireland

Tricuspid Valve Infective Endocarditis with Severe Tricuspid Regurgitation

Robert Doyle, Mark Wilkinson

DOI: 10.12659/AJCR.948728

Am J Case Rep 2025; 26:e948728

468 2,275 0

#948728

08 Oct 2025 : Case report  Ireland

Tricuspid Valve Infective Endocarditis with Severe Tricuspid Regurgitation

Robert Doyle, Mark Wilkinson

DOI: 10.12659/AJCR.948728

Am J Case Rep 2025; 26:e948728

468 2275 0

#949785

29 Oct 2025 : Case report  China

Gastric Adenocarcinoma Resembling Submucosal Tumor: A Case Report

Hongli Liu, Chao Deng, Rui Song, Juan Li, Song He, Zhihang Zhou, Suhua Wu, Hongdan Cao, Lin Lv ORCID logo

DOI: 10.12659/AJCR.949785

Am J Case Rep 2025; 26:e949785

595 2,252 0

#949785

29 Oct 2025 : Case report  China

Gastric Adenocarcinoma Resembling Submucosal Tumor: A Case Report

Hongli Liu, Chao Deng, Rui Song, Juan Li, Song He, Zhihang Zhou, Suhua Wu, Hongdan Cao, Lin Lv ORCID logo

DOI: 10.12659/AJCR.949785

Am J Case Rep 2025; 26:e949785

595 2252 0

#948301

28 Oct 2025 : Case report  China

Successful Treatment with a 6.3-Fr Disposable Digital Flexible Ureteroscope and Holmium Laser Lithotripsy in a 50-Year-Old Man with Large Bilateral Ureteral Stones and Hydronephrosis

Xiang Xu, Kaifeng Mao, Feihong Xu, Weiyong Zhong, Wei Zhao, Mi Zhang, Zhenquan Lu, Genggeng Wei

DOI: 10.12659/AJCR.948301

Am J Case Rep 2025; 26:e948301

505 1,969 0

#948301

28 Oct 2025 : Case report  China

Successful Treatment with a 6.3-Fr Disposable Digital Flexible Ureteroscope and Holmium Laser Lithotripsy in a 50-Year-Old Man with Large Bilateral Ureteral Stones and Hydronephrosis

Xiang Xu, Kaifeng Mao, Feihong Xu, Weiyong Zhong, Wei Zhao, Mi Zhang, Zhenquan Lu, Genggeng Wei

DOI: 10.12659/AJCR.948301

Am J Case Rep 2025; 26:e948301

505 1969 0

#949826

23 Oct 2025 : Case report  China

Left Ventricle Libman-Sacks Endocarditis Secondary to Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report

Zi-hao Yang, Wen-qing Gong, Ying Liu, Min-juan Zheng

DOI: 10.12659/AJCR.949826

Am J Case Rep 2025; 26:e949826

597 1,461 0

#949826

23 Oct 2025 : Case report  China

Left Ventricle Libman-Sacks Endocarditis Secondary to Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report

Zi-hao Yang, Wen-qing Gong, Ying Liu, Min-juan Zheng

DOI: 10.12659/AJCR.949826

Am J Case Rep 2025; 26:e949826

597 1461 0

In Press

Case report  USA

Single-Dose Nivolumab as a Trigger of Myocarditis, Myositis, and Myasthenia Gravis Overlap Syndrome With La...

Am J Case Rep In Press; DOI: 10.12659/AJCR.953173  

Case report  Japan

A 73-Year-Old Man With a Late Isolated Brain Metastasis of Clear Cell Renal Cell Carcinoma Following a Dura...

Am J Case Rep In Press; DOI: 10.12659/AJCR.953192  

Case report  China

Ultrasound Identification of Right Internal Jugular Vein Occlusion After Catheterization in a Premature Infant

Am J Case Rep In Press; DOI: 10.12659/AJCR.952818  

Case report  China

Heyde Syndrome Complicated by Pulmonary Embolism Before Transcatheter Aortic Valve Replacement: A Clinical ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.953608  

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923