Adverse events of drug therapy
18 Dec 2025 : Case report 
Drug-Induced Lupus Erythematosus After 14 Years of Carbamazepine Use in a Patient With Neuromyelitis Optica Spectrum Disorder: A Case Report
Naho Ayuzawa-Takeda, Keisuke Saito, Hidetoshi Yanagida, Tomoko Oeda
DOI: 10.12659/AJCR.949233
Am J Case Rep 2025; 26:e949233
1,171 4,133 0
18 Dec 2025 : Case report
Drug-Induced Lupus Erythematosus After 14 Years of Carbamazepine Use in a Patient With Neuromyelitis Optica Spectrum Disorder: A Case Report
Naho Ayuzawa-Takeda, Keisuke Saito, Hidetoshi Yanagida, Tomoko Oeda
DOI: 10.12659/AJCR.949233
Am J Case Rep 2025; 26:e949233
1171 4133 0
07 Dec 2025 : Case report 
Acute Kidney Injury from Mononuclear Cell-Predominated Interstitial Nephritis After Introduction of a Glucagon-Like Peptide-1 Receptor Agonist: A Case Report
Raweekarn Itsathitpaisarn, Nattavong Suksawad, Watsapol Wongwikrom, Jerasit Surintrspanont 
, Thana Thongsricome
DOI: 10.12659/AJCR.949913
Am J Case Rep 2025; 26:e949913
1,171 2,728 0
07 Dec 2025 : Case report
Acute Kidney Injury from Mononuclear Cell-Predominated Interstitial Nephritis After Introduction of a Glucagon-Like Peptide-1 Receptor Agonist: A Case Report
Raweekarn Itsathitpaisarn, Nattavong Suksawad, Watsapol Wongwikrom, Jerasit Surintrspanont , Thana Thongsricome
DOI: 10.12659/AJCR.949913
Am J Case Rep 2025; 26:e949913
1171 2728 0
06 Dec 2025 : Case report 
Acute Kidney Injury After Accelerated Dosing of Tirzepatide in a Patient with Multiple Comorbidities: A Case Report
Abdulelah H. Almansour
DOI: 10.12659/AJCR.950781
Am J Case Rep 2025; 26:e950781
1,681 13,980 0
06 Dec 2025 : Case report
Acute Kidney Injury After Accelerated Dosing of Tirzepatide in a Patient with Multiple Comorbidities: A Case Report
Abdulelah H. Almansour
DOI: 10.12659/AJCR.950781
Am J Case Rep 2025; 26:e950781
1681 13980 0
18 Nov 2025 : Case report 
Exploring Maralixibat for Treatment-Resistant Pruritus in Intrahepatic Cholestasis of Pregnancy and Primary Biliary Cholangitis: A Case Report
Lara Alexandra Bersuch , Andrea De Gottardi
DOI: 10.12659/AJCR.949019
Am J Case Rep 2025; 26:e949019
1,194 2,910 0
18 Nov 2025 : Case report
Exploring Maralixibat for Treatment-Resistant Pruritus in Intrahepatic Cholestasis of Pregnancy and Primary Biliary Cholangitis: A Case Report
Lara Alexandra Bersuch , Andrea De Gottardi
DOI: 10.12659/AJCR.949019
Am J Case Rep 2025; 26:e949019
1194 2910 0
23 Nov 2025 : Case report
Nocardia farcinica Brain Abscess in a Glucocorticoid-Treated Patient with Giant-Cell Arteritis: A Case Report
Simon Valenti , Masahiro Kogami , Mai Suzuki, Toshio Naito , Naoto Tamura
DOI: 10.12659/AJCR.949616
Am J Case Rep 2025; 26:e949616
1,118 1,709 0
23 Nov 2025 : Case report
Nocardia farcinica Brain Abscess in a Glucocorticoid-Treated Patient with Giant-Cell Arteritis: A Case Report
Simon Valenti , Masahiro Kogami , Mai Suzuki, Toshio Naito , Naoto Tamura
DOI: 10.12659/AJCR.949616
Am J Case Rep 2025; 26:e949616
1118 1709 0
24 Nov 2025 : Case report 
Hypophysitis Induced by Tislelizumab: A Case Report of Somnolence and Delirium with Elevated Eosinophils
Fenglin Hu, Ni Lou, Guolin Wu
DOI: 10.12659/AJCR.948143
Am J Case Rep 2025; 26:e948143
1,078 1,544 0
24 Nov 2025 : Case report
Hypophysitis Induced by Tislelizumab: A Case Report of Somnolence and Delirium with Elevated Eosinophils
Fenglin Hu, Ni Lou, Guolin Wu
DOI: 10.12659/AJCR.948143
Am J Case Rep 2025; 26:e948143
1078 1544 0
22 Nov 2025 : Case report
Sodium Valproate-Associated Thrombocytopenia in Antiepileptic Drug Polypharmacy: A Case Report and Review of the Literature
Xuehua Deng, Xinyi Tu, Shiwen Yang, Jianghong Xiong, Yuanjian Yang, Shuzhen Jiang
DOI: 10.12659/AJCR.949595
Am J Case Rep 2025; 26:e949595
1,247 5,889 0
22 Nov 2025 : Case report
Sodium Valproate-Associated Thrombocytopenia in Antiepileptic Drug Polypharmacy: A Case Report and Review of the Literature
Xuehua Deng, Xinyi Tu, Shiwen Yang, Jianghong Xiong, Yuanjian Yang, Shuzhen Jiang
DOI: 10.12659/AJCR.949595
Am J Case Rep 2025; 26:e949595
1247 5889 0
14 Nov 2025 : Case report 
Reverse Takotsubo Cardiomyopathy After Treatment of Asymptomatic Bradycardia Prior to Anesthesia Induction in a Young Woman Undergoing Elective Rhinoplasty: A Case Report
Samantha Henry, Kelly Rothbart, Amit Prasad
DOI: 10.12659/AJCR.950112
Am J Case Rep 2025; 26:e950112
1,158 1,745 0
14 Nov 2025 : Case report
Reverse Takotsubo Cardiomyopathy After Treatment of Asymptomatic Bradycardia Prior to Anesthesia Induction in a Young Woman Undergoing Elective Rhinoplasty: A Case Report
Samantha Henry, Kelly Rothbart, Amit Prasad
DOI: 10.12659/AJCR.950112
Am J Case Rep 2025; 26:e950112
1158 1745 0
11 Nov 2025 : Case report
Delayed-Onset Rhabdomyolysis of Bilateral Lower Extremities Following Statin Therapy in a 63-Year-Old Woman: A Case Report
Martin Nguyen , Olivia N. Nicoloudakis, Patrick M. Farry II, Esabelle D. Gervasio, Sevar Yaldo, Michael Iannetti
DOI: 10.12659/AJCR.948601
Am J Case Rep 2025; 26:e948601
1,537 7,598 0
11 Nov 2025 : Case report
Delayed-Onset Rhabdomyolysis of Bilateral Lower Extremities Following Statin Therapy in a 63-Year-Old Woman: A Case Report
Martin Nguyen , Olivia N. Nicoloudakis, Patrick M. Farry II, Esabelle D. Gervasio, Sevar Yaldo, Michael Iannetti
DOI: 10.12659/AJCR.948601
Am J Case Rep 2025; 26:e948601
1537 7598 0
24 Oct 2025 : Case report
Medical Management of an Infusion Site Extravasation Injury After Peripheral Intravenous Infusion of Ado-Trastuzumab Emtansine in a 38-Year-Old Woman With Breast Cancer: A Case Report
Eleni M. Gamvroulas, Patricia Jeppson, Mei Wei
DOI: 10.12659/AJCR.949828
Am J Case Rep 2025; 26:e949828
831 2,183 0
24 Oct 2025 : Case report
Medical Management of an Infusion Site Extravasation Injury After Peripheral Intravenous Infusion of Ado-Trastuzumab Emtansine in a 38-Year-Old Woman With Breast Cancer: A Case Report
Eleni M. Gamvroulas, Patricia Jeppson, Mei Wei
DOI: 10.12659/AJCR.949828
Am J Case Rep 2025; 26:e949828
831 2183 0
21 Oct 2025 : Case report
Methimazole-Induced Antithyroid Arthritis Syndrome in Graves' Disease Management: A Case Report
Kin-Weng Sun , Aixin Wu
DOI: 10.12659/AJCR.949509
Am J Case Rep 2025; 26:e949509
915 4,814 0
21 Oct 2025 : Case report
Methimazole-Induced Antithyroid Arthritis Syndrome in Graves' Disease Management: A Case Report
Kin-Weng Sun , Aixin Wu
DOI: 10.12659/AJCR.949509
Am J Case Rep 2025; 26:e949509
915 4814 0
12 Oct 2025 : Case report
Spontaneous Pleural, Pericardial, and Intracranial Hemorrhages in a Patient with End-Stage Kidney Disease Receiving Apixaban: A Case Report
Adebola Oluwabusayo Adetiloye , Moustafa Ismail, Farhana K. Alladin, Olurotimi J. Badero
DOI: 10.12659/AJCR.948821
Am J Case Rep 2025; 26:e948821
674 3,084 0
12 Oct 2025 : Case report
Spontaneous Pleural, Pericardial, and Intracranial Hemorrhages in a Patient with End-Stage Kidney Disease Receiving Apixaban: A Case Report
Adebola Oluwabusayo Adetiloye , Moustafa Ismail, Farhana K. Alladin, Olurotimi J. Badero
DOI: 10.12659/AJCR.948821
Am J Case Rep 2025; 26:e948821
674 3084 0
03 Sep 2025 : Case report 
Portomesenteric Vein Thrombosis Following Sleeve Gastrectomy: A Case Report and Literature Review
Jóse Sergio Verboonen Sotelo, Jaime Ponce de León Palomares, Jeffry Romero Manzano, Hector Joaquin Pérez Corzo, Jesus Antonio Villalobos López, Gustavo Adolfo Linden Pérez-Gavilán, Guillermo Vega Tostado, Gabriela Verboonen Partida
DOI: 10.12659/AJCR.947151
Am J Case Rep 2025; 26:e947151
582 2,316 0
03 Sep 2025 : Case report
Portomesenteric Vein Thrombosis Following Sleeve Gastrectomy: A Case Report and Literature Review
Jóse Sergio Verboonen Sotelo, Jaime Ponce de León Palomares, Jeffry Romero Manzano, Hector Joaquin Pérez Corzo, Jesus Antonio Villalobos López, Gustavo Adolfo Linden Pérez-Gavilán, Guillermo Vega Tostado, Gabriela Verboonen Partida
DOI: 10.12659/AJCR.947151
Am J Case Rep 2025; 26:e947151
582 2316 0
05 Oct 2025 : Case report
Cardiotoxicity Secondary to Accidental Tilmicosin (Micotil®300) Ingestion in a Young Shepherd: A Case Report
Zein B. Sheikh, Bayan S. Alalawi , Fadyah M. Alradaddi, Ahlam Y. Elbadri
DOI: 10.12659/AJCR.948094
Am J Case Rep 2025; 26:e948094
470 2,050 0
05 Oct 2025 : Case report
Cardiotoxicity Secondary to Accidental Tilmicosin (Micotil®300) Ingestion in a Young Shepherd: A Case Report
Zein B. Sheikh, Bayan S. Alalawi , Fadyah M. Alradaddi, Ahlam Y. Elbadri
DOI: 10.12659/AJCR.948094
Am J Case Rep 2025; 26:e948094
470 2050 0
09 Sep 2025 : Case report
Adverse Dermatological Reaction to Mycophenolate Mofetil in a Patient with Systemic Lupus Erythematosus: A Case Report
Yuxin Cao, Haijuan Chen, Zhimei Liao, Hui Xiang, Xia Zhang, Xiaorong Di, Wei Tang, Li Ding, Lianming Liao
DOI: 10.12659/AJCR.948698
Am J Case Rep 2025; 26:e948698
587 2,695 0
09 Sep 2025 : Case report
Adverse Dermatological Reaction to Mycophenolate Mofetil in a Patient with Systemic Lupus Erythematosus: A Case Report
Yuxin Cao, Haijuan Chen, Zhimei Liao, Hui Xiang, Xia Zhang, Xiaorong Di, Wei Tang, Li Ding, Lianming Liao
DOI: 10.12659/AJCR.948698
Am J Case Rep 2025; 26:e948698
587 2695 0
28 Aug 2025 : Case report 
Pancreatic Inflammation Induced by Immune Checkpoint Inhibitors in Melanoma Treatment: A Case Report
Abdo I. El Tawil, Beatriz A. Mendes, Leandro A.F. Machoski, Micheli F. Domingos, Noelle S. Wassano, Sérgio O. Ioshii, Eduardo J.B. Ramos
DOI: 10.12659/AJCR.948580
Am J Case Rep 2025; 26:e948580
590 1,493 0
28 Aug 2025 : Case report
Pancreatic Inflammation Induced by Immune Checkpoint Inhibitors in Melanoma Treatment: A Case Report
Abdo I. El Tawil, Beatriz A. Mendes, Leandro A.F. Machoski, Micheli F. Domingos, Noelle S. Wassano, Sérgio O. Ioshii, Eduardo J.B. Ramos
DOI: 10.12659/AJCR.948580
Am J Case Rep 2025; 26:e948580
590 1493 0
29 Aug 2025 : Case report
Radial Periosteal Distraction as a Novel Intervention for Raynaud Syndrome with Gangrene: A Case Report
Xiaoyu Zheng, Yang Yang, Hongliang Jin, Yiguo Chen, Wei Wang
DOI: 10.12659/AJCR.948422
Am J Case Rep 2025; 26:e948422
592 1,707 0
29 Aug 2025 : Case report
Radial Periosteal Distraction as a Novel Intervention for Raynaud Syndrome with Gangrene: A Case Report
Xiaoyu Zheng, Yang Yang, Hongliang Jin, Yiguo Chen, Wei Wang
DOI: 10.12659/AJCR.948422
Am J Case Rep 2025; 26:e948422
592 1707 0
26 Aug 2025 : Case report
Management of Rheumatoid Arthritis in a Patient with Aplastic Anemia and Ulcerative Colitis: A Case Report
Amira M. Elfergani , Aixa Toledo-Garcia
DOI: 10.12659/AJCR.949020
Am J Case Rep 2025; 26:e949020
700 1,704 0
26 Aug 2025 : Case report
Management of Rheumatoid Arthritis in a Patient with Aplastic Anemia and Ulcerative Colitis: A Case Report
Amira M. Elfergani , Aixa Toledo-Garcia
DOI: 10.12659/AJCR.949020
Am J Case Rep 2025; 26:e949020
700 1704 0
25 Aug 2025 : Case report
Rapid Progression of Primary Hepatic Neuroendocrine Carcinoma: A Case Report Demonstrating Drastic Oncological Behavior
Rina Kobayashi, Tomohide Hori , Makoto Yamawaki, Shigeki Nakayama, Satoru Umegae, Takao Iwanaga, Ryutaro Nishikawa, Takahiro Shimoyama, Sakurako Suzuki, Shinichiro Atsumi, Hiroshi Hasegawa, Shigehito Nakashima, Kunihiro Higuchi, Kentaro Onishi, Ryotaro Sakaguchi, Shoichi Morita, Haruka Miyao, Saki Aota, Hikaru Ohtani, Takayuki Yamamoto
DOI: 10.12659/AJCR.948500
Am J Case Rep 2025; 26:e948500
824 1,527 0
25 Aug 2025 : Case report
Rapid Progression of Primary Hepatic Neuroendocrine Carcinoma: A Case Report Demonstrating Drastic Oncological Behavior
Rina Kobayashi, Tomohide Hori , Makoto Yamawaki, Shigeki Nakayama, Satoru Umegae, Takao Iwanaga, Ryutaro Nishikawa, Takahiro Shimoyama, Sakurako Suzuki, Shinichiro Atsumi, Hiroshi Hasegawa, Shigehito Nakashima, Kunihiro Higuchi, Kentaro Onishi, Ryotaro Sakaguchi, Shoichi Morita, Haruka Miyao, Saki Aota, Hikaru Ohtani, Takayuki Yamamoto
DOI: 10.12659/AJCR.948500
Am J Case Rep 2025; 26:e948500
824 1527 0
11 Aug 2025 : Case report
Complex Interplay Between Sweet Syndrome and Therapy-Related Myelodysplastic Syndrome After B-Cell Lymphoma Treatment: A Case Report
Hiroto Yamashita, Shuhei Kurosawa, Yukari Hamamura, Yoko Tateishi, Hiroyuki Hayashi, Takeshi Kambara, Tomonori Nakazato
DOI: 10.12659/AJCR.949165
Am J Case Rep 2025; 26:e949165
1,401 1,461 0
11 Aug 2025 : Case report
Complex Interplay Between Sweet Syndrome and Therapy-Related Myelodysplastic Syndrome After B-Cell Lymphoma Treatment: A Case Report
Hiroto Yamashita, Shuhei Kurosawa, Yukari Hamamura, Yoko Tateishi, Hiroyuki Hayashi, Takeshi Kambara, Tomonori Nakazato
DOI: 10.12659/AJCR.949165
Am J Case Rep 2025; 26:e949165
1401 1461 0
05 Aug 2025 : Case report
Recurrent Severe Hyponatremia Following Polyethylene Glycol Electrolyte Lavage Solution with Ascorbic Acid in a Patient with Undiagnosed Syndrome of Inappropriate Antidiuretic Hormone Secretion
Koichi Soga , Yuto Suzuki, Fuki Hayakawa, Takeshi Fujiwara, Takahiro Ota, Ikuhiro Kobori , Masaya Tamano
DOI: 10.12659/AJCR.948355
Am J Case Rep 2025; 26:e948355
1,167 1,714 0
05 Aug 2025 : Case report
Recurrent Severe Hyponatremia Following Polyethylene Glycol Electrolyte Lavage Solution with Ascorbic Acid in a Patient with Undiagnosed Syndrome of Inappropriate Antidiuretic Hormone Secretion
Koichi Soga , Yuto Suzuki, Fuki Hayakawa, Takeshi Fujiwara, Takahiro Ota, Ikuhiro Kobori , Masaya Tamano
DOI: 10.12659/AJCR.948355
Am J Case Rep 2025; 26:e948355
1167 1714 0
12 Jul 2025 : Case report 
HIV-Negative African American Man with Gastrointestinal Kaposi Sarcoma Associated with Adalimumab Treatment for Cardiac Sarcoidosis: A Case Report
Vaishnavi Ghantasala, Aadi Palvia, Abhiram Rao Damera, Marcela Salomao, Lucinda A. Harris, Jana G. Hashash, Karthik Gnanapandithan
DOI: 10.12659/AJCR.947163
Am J Case Rep 2025; 26:e947163
985 1,882 0
12 Jul 2025 : Case report
HIV-Negative African American Man with Gastrointestinal Kaposi Sarcoma Associated with Adalimumab Treatment for Cardiac Sarcoidosis: A Case Report
Vaishnavi Ghantasala, Aadi Palvia, Abhiram Rao Damera, Marcela Salomao, Lucinda A. Harris, Jana G. Hashash, Karthik Gnanapandithan
DOI: 10.12659/AJCR.947163
Am J Case Rep 2025; 26:e947163
985 1882 0
03 Jun 2025 : Case report
Lung Transplant Success in Severe Diquat Poisoning: A Case Report
Fanjie Meng , Yan Zhang, Hongfei Cai, Fanyu Meng, Bohao Liu, Yang Li
DOI: 10.12659/AJCR.947421
Am J Case Rep 2025; 26:e947421
1,325 1,963 0
03 Jun 2025 : Case report
Lung Transplant Success in Severe Diquat Poisoning: A Case Report
Fanjie Meng , Yan Zhang, Hongfei Cai, Fanyu Meng, Bohao Liu, Yang Li
DOI: 10.12659/AJCR.947421
Am J Case Rep 2025; 26:e947421
1325 1963 0
17 Jun 2025 : Case report 
Twenty Years of Continuous Bisphosphonate Use Leading to Atypical Bilateral Femoral Fractures: A Case Report
Anna Maria Monachino, Massimo Berdini , Valerio Tiburzi , Roberto Procaccini, Antonio Pompilio Gigante
DOI: 10.12659/AJCR.946435
Am J Case Rep 2025; 26:e946435
1,011 3,547 0
17 Jun 2025 : Case report
Twenty Years of Continuous Bisphosphonate Use Leading to Atypical Bilateral Femoral Fractures: A Case Report
Anna Maria Monachino, Massimo Berdini , Valerio Tiburzi , Roberto Procaccini, Antonio Pompilio Gigante
DOI: 10.12659/AJCR.946435
Am J Case Rep 2025; 26:e946435
1011 3547 0
13 Jun 2025 : Case report
Accelerated Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome in Response to TMP-SMX: A Case Report
Emily J. Sanchez, Elizabeth A. Cheiky
DOI: 10.12659/AJCR.948217
Am J Case Rep 2025; 26:e948217
1,016 4,290 0
13 Jun 2025 : Case report
Accelerated Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome in Response to TMP-SMX: A Case Report
Emily J. Sanchez, Elizabeth A. Cheiky
DOI: 10.12659/AJCR.948217
Am J Case Rep 2025; 26:e948217
1016 4290 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953266
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953149
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.954079
Case report 
Am J Case Rep In Press; DOI: 10.12659/AJCR.953801
Most Viewed Current Articles
07 Dec 2021 : Case report
24,045,606
DOI :10.12659/AJCR.934347
Am J Case Rep 2021; 22:e934347
06 Dec 2021 : Case report
179,470
DOI :10.12659/AJCR.934406
Am J Case Rep 2021; 22:e934406
21 Jun 2024 : Case report
123,287
DOI :10.12659/AJCR.944371
Am J Case Rep 2024; 25:e944371
07 Mar 2024 : Case report
67,705
DOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133