Challenging differential diagnosis
20 Aug 2025 : Case report 
Diagnosis and Management of Large Extraosseous Myxoid Chondrosarcoma of the Buttocks: A Case Report
Qing Hong Lai, Chun Mei Zhong, Xue Qi Sun, Hua Ye, Yan Zhang, Jia Jing Tu, Jun Feng Sun
DOI: 10.12659/AJCR.947135
Am J Case Rep 2025; 26:e947135
414 1,220 0
20 Aug 2025 : Case report
Diagnosis and Management of Large Extraosseous Myxoid Chondrosarcoma of the Buttocks: A Case Report
Qing Hong Lai, Chun Mei Zhong, Xue Qi Sun, Hua Ye, Yan Zhang, Jia Jing Tu, Jun Feng Sun
DOI: 10.12659/AJCR.947135
Am J Case Rep 2025; 26:e947135
414 1220 0
18 Aug 2025 : Case report
Balancing Empirical Treatment and Comprehensive Evaluation in a Case of Suspected Rickettsial Infection: A Diagnostic Dilemma in Recurrent Fever
Jing Ding, Ju Tian, Xingqi Chen
DOI: 10.12659/AJCR.948614
Am J Case Rep 2025; 26:e948614
524 904 0
18 Aug 2025 : Case report
Balancing Empirical Treatment and Comprehensive Evaluation in a Case of Suspected Rickettsial Infection: A Diagnostic Dilemma in Recurrent Fever
Jing Ding, Ju Tian, Xingqi Chen
DOI: 10.12659/AJCR.948614
Am J Case Rep 2025; 26:e948614
524 904 0
15 Aug 2025 : Case report
HELLP Syndrome with Hepatic and Thoracic Complications: Insights From a Case of Spontaneous Liver Rupture
Sanqiang Niu, Kangjun Yu, Yayun Cheng, Ning Liu
DOI: 10.12659/AJCR.949380
Am J Case Rep 2025; 26:e949380
521 1,560 0
15 Aug 2025 : Case report
HELLP Syndrome with Hepatic and Thoracic Complications: Insights From a Case of Spontaneous Liver Rupture
Sanqiang Niu, Kangjun Yu, Yayun Cheng, Ning Liu
DOI: 10.12659/AJCR.949380
Am J Case Rep 2025; 26:e949380
521 1560 0
10 Aug 2025 : Case report 
Disseminated Blastomycosis: A Case of Multisite Infection in an Immunocompetent Patient
Vishnu Teja Kommineni 
, Joshua J. Jagodzinski, Emilia Elena Petcu, Celestine Odenigbo, Rathnamitreyee Vegunta , Igor Dumic
DOI: 10.12659/AJCR.949647
Am J Case Rep 2025; 26:e949647
933 1,073 0
10 Aug 2025 : Case report
Disseminated Blastomycosis: A Case of Multisite Infection in an Immunocompetent Patient
Vishnu Teja Kommineni , Joshua J. Jagodzinski, Emilia Elena Petcu, Celestine Odenigbo, Rathnamitreyee Vegunta , Igor Dumic
DOI: 10.12659/AJCR.949647
Am J Case Rep 2025; 26:e949647
933 1073 0
11 Aug 2025 : Case report 
Complex Interplay Between Sweet Syndrome and Therapy-Related Myelodysplastic Syndrome After B-Cell Lymphoma Treatment: A Case Report
Hiroto Yamashita, Shuhei Kurosawa, Yukari Hamamura, Yoko Tateishi, Hiroyuki Hayashi, Takeshi Kambara, Tomonori Nakazato
DOI: 10.12659/AJCR.949165
Am J Case Rep 2025; 26:e949165
1,298 1,237 0
11 Aug 2025 : Case report
Complex Interplay Between Sweet Syndrome and Therapy-Related Myelodysplastic Syndrome After B-Cell Lymphoma Treatment: A Case Report
Hiroto Yamashita, Shuhei Kurosawa, Yukari Hamamura, Yoko Tateishi, Hiroyuki Hayashi, Takeshi Kambara, Tomonori Nakazato
DOI: 10.12659/AJCR.949165
Am J Case Rep 2025; 26:e949165
1298 1237 0
09 Aug 2025 : Case report
Primary Adrenal Lymphoma Diagnosed by Endoscopic Ultrasound Fine-Needle Aspiration Biopsy: A Case Report
Yuzheng Zhao, Ning Chen
DOI: 10.12659/AJCR.948833
Am J Case Rep 2025; 26:e948833
775 943 0
09 Aug 2025 : Case report
Primary Adrenal Lymphoma Diagnosed by Endoscopic Ultrasound Fine-Needle Aspiration Biopsy: A Case Report
Yuzheng Zhao, Ning Chen
DOI: 10.12659/AJCR.948833
Am J Case Rep 2025; 26:e948833
775 943 0
06 Aug 2025 : Case report
Unveiling Maternal Germline Mosaicism in X-Linked Alport Syndrome by Advanced Genetic Testing
Yuting Shen, Caihong Liu, Wei Wei, Yongxiu Huang , Qian Zhu, Yuliang Zhao
DOI: 10.12659/AJCR.947287
Am J Case Rep 2025; 26:e947287
859 935 0
06 Aug 2025 : Case report
Unveiling Maternal Germline Mosaicism in X-Linked Alport Syndrome by Advanced Genetic Testing
Yuting Shen, Caihong Liu, Wei Wei, Yongxiu Huang , Qian Zhu, Yuliang Zhao
DOI: 10.12659/AJCR.947287
Am J Case Rep 2025; 26:e947287
859 935 0
05 Aug 2025 : Case report
Recurrent Severe Hyponatremia Following Polyethylene Glycol Electrolyte Lavage Solution with Ascorbic Acid in a Patient with Undiagnosed Syndrome of Inappropriate Antidiuretic Hormone Secretion
Koichi Soga , Yuto Suzuki, Fuki Hayakawa, Takeshi Fujiwara, Takahiro Ota, Ikuhiro Kobori , Masaya Tamano
DOI: 10.12659/AJCR.948355
Am J Case Rep 2025; 26:e948355
1,029 1,457 0
05 Aug 2025 : Case report
Recurrent Severe Hyponatremia Following Polyethylene Glycol Electrolyte Lavage Solution with Ascorbic Acid in a Patient with Undiagnosed Syndrome of Inappropriate Antidiuretic Hormone Secretion
Koichi Soga , Yuto Suzuki, Fuki Hayakawa, Takeshi Fujiwara, Takahiro Ota, Ikuhiro Kobori , Masaya Tamano
DOI: 10.12659/AJCR.948355
Am J Case Rep 2025; 26:e948355
1029 1457 0
04 Aug 2025 : Case report 
Visceral Arterial Thrombosis Linked to Long-Term Oral Contraceptives and Smoking: A Case Report
Laura Leci Tahiri, Valdete Haxhibeqiri
DOI: 10.12659/AJCR.948398
Am J Case Rep 2025; 26:e948398
774 1,316 0
04 Aug 2025 : Case report
Visceral Arterial Thrombosis Linked to Long-Term Oral Contraceptives and Smoking: A Case Report
Laura Leci Tahiri, Valdete Haxhibeqiri
DOI: 10.12659/AJCR.948398
Am J Case Rep 2025; 26:e948398
774 1316 0
03 Aug 2025 : Case report 
Personalized In Vitro Fertilization Protocols in Premature Ovarian Insufficiency and Male-Factor Infertility: A Case Series
Agus Heriyanto, Dian Tjahyadi, Anita Rachmawati, Ayu Insafi Mulyantari
DOI: 10.12659/AJCR.947396
Am J Case Rep 2025; 26:e947396
1,159 1,611 0
03 Aug 2025 : Case report
Personalized In Vitro Fertilization Protocols in Premature Ovarian Insufficiency and Male-Factor Infertility: A Case Series
Agus Heriyanto, Dian Tjahyadi, Anita Rachmawati, Ayu Insafi Mulyantari
DOI: 10.12659/AJCR.947396
Am J Case Rep 2025; 26:e947396
1159 1611 0
02 Aug 2025 : Case report 
Advanced Strategies for Managing Pleuroperitoneal Communication in Peritoneal Dialysis Patients: Report of Two Cases
Paolo Ria , Luca Luongo, Vilma Martella, Anna Zito , Silvia Matino, Silvia Barbarini, Paolo Protopapa, Davide Gianfreda , Antonio De Pascalis, Luigi Gaetano Andriolo
DOI: 10.12659/AJCR.947860
Am J Case Rep 2025; 26:e947860
1,044 1,378 0
02 Aug 2025 : Case report
Advanced Strategies for Managing Pleuroperitoneal Communication in Peritoneal Dialysis Patients: Report of Two Cases
Paolo Ria , Luca Luongo, Vilma Martella, Anna Zito , Silvia Matino, Silvia Barbarini, Paolo Protopapa, Davide Gianfreda , Antonio De Pascalis, Luigi Gaetano Andriolo
DOI: 10.12659/AJCR.947860
Am J Case Rep 2025; 26:e947860
1044 1378 0
01 Aug 2025 : Case report 
Immunoadsorption as a Rescue Therapy for Very High Anti-B Titer in ABO-Incompatible Kidney Transplantation
Chanyanuch Rakpithayanon, Nattapakorn Mai-on, Sirihatai Konwai , Thunyatorn Wuttiputhanun, Natavudh Townamchai , Methee Sutherasan, Julin Opanuraks, Yingyos Avihingsanon , Suwasin Udomkarnjananun
DOI: 10.12659/AJCR.948529
Am J Case Rep 2025; 26:e948529
733 988 0
01 Aug 2025 : Case report
Immunoadsorption as a Rescue Therapy for Very High Anti-B Titer in ABO-Incompatible Kidney Transplantation
Chanyanuch Rakpithayanon, Nattapakorn Mai-on, Sirihatai Konwai , Thunyatorn Wuttiputhanun, Natavudh Townamchai , Methee Sutherasan, Julin Opanuraks, Yingyos Avihingsanon , Suwasin Udomkarnjananun
DOI: 10.12659/AJCR.948529
Am J Case Rep 2025; 26:e948529
733 988 0
27 Jul 2025 : Case report
One Patient with 3 Antibody-Confirmed Neurological Autoimmune Syndromes: A Case Report and Review of the Literature
Lauren A. Nguyen, Frishan Rocel O. Paulo, Jordan J. Petersen, J. Douglas Miles
DOI: 10.12659/AJCR.948329
Am J Case Rep 2025; 26:e948329
1,090 1,631 0
27 Jul 2025 : Case report
One Patient with 3 Antibody-Confirmed Neurological Autoimmune Syndromes: A Case Report and Review of the Literature
Lauren A. Nguyen, Frishan Rocel O. Paulo, Jordan J. Petersen, J. Douglas Miles
DOI: 10.12659/AJCR.948329
Am J Case Rep 2025; 26:e948329
1090 1631 0
30 Jul 2025 : Case report
Successful Management of Severe Refractory ARDS in Hemophagocytic Lymphohistiocytosis with VV-ECMO: A Case Report and Analysis
Mengqi Guan, Yan Qian, Zihua Tang, Yingya Cao, Xiaogan Jiang, Weihua Lu, Qiancheng Xu
DOI: 10.12659/AJCR.949154
Am J Case Rep 2025; 26:e949154
1,006 1,605 0
30 Jul 2025 : Case report
Successful Management of Severe Refractory ARDS in Hemophagocytic Lymphohistiocytosis with VV-ECMO: A Case Report and Analysis
Mengqi Guan, Yan Qian, Zihua Tang, Yingya Cao, Xiaogan Jiang, Weihua Lu, Qiancheng Xu
DOI: 10.12659/AJCR.949154
Am J Case Rep 2025; 26:e949154
1006 1605 0
25 Jul 2025 : Case report
Distinguishing Wernicke Encephalopathy from Artery of Percheron Infarction in a 43-Year-Old Man: A Case Report
Syed Raza, Salma Mohamed, Nazia Naz S. Khan
DOI: 10.12659/AJCR.948636
Am J Case Rep 2025; 26:e948636
827 1,043 0
25 Jul 2025 : Case report
Distinguishing Wernicke Encephalopathy from Artery of Percheron Infarction in a 43-Year-Old Man: A Case Report
Syed Raza, Salma Mohamed, Nazia Naz S. Khan
DOI: 10.12659/AJCR.948636
Am J Case Rep 2025; 26:e948636
827 1043 0
24 Jul 2025 : Case report
Ectopic Adrenocortical Adenoma Causing Malignant Hypertension and Hypokalemia
Xiaoyong Hu , Djandan Tadum Arthur Vithran , Zhaoying Yang, Hongjian Li
DOI: 10.12659/AJCR.948022
Am J Case Rep 2025; 26:e948022
963 1,850 0
24 Jul 2025 : Case report
Ectopic Adrenocortical Adenoma Causing Malignant Hypertension and Hypokalemia
Xiaoyong Hu , Djandan Tadum Arthur Vithran , Zhaoying Yang, Hongjian Li
DOI: 10.12659/AJCR.948022
Am J Case Rep 2025; 26:e948022
963 1850 0
22 Jul 2025 : Case report
Leukemoid Reactions in Pancreatic Cancer: A Case Series
Teng Huang, Tangchun Liu, Siqi Liu, Zhengfei Yang
DOI: 10.12659/AJCR.948491
Am J Case Rep 2025; 26:e948491
1,107 2,637 0
22 Jul 2025 : Case report
Leukemoid Reactions in Pancreatic Cancer: A Case Series
Teng Huang, Tangchun Liu, Siqi Liu, Zhengfei Yang
DOI: 10.12659/AJCR.948491
Am J Case Rep 2025; 26:e948491
1107 2637 0
21 Jul 2025 : Case report
Diagnosing Disseminated Peritoneal Leiomyomatosis: Malignancy-Like Presentation in a 59-Year-Old Woman
Changchao Xiao, Haixing Ju, Jun Cao
DOI: 10.12659/AJCR.947246
Am J Case Rep 2025; 26:e947246
800 1,375 0
21 Jul 2025 : Case report
Diagnosing Disseminated Peritoneal Leiomyomatosis: Malignancy-Like Presentation in a 59-Year-Old Woman
Changchao Xiao, Haixing Ju, Jun Cao
DOI: 10.12659/AJCR.947246
Am J Case Rep 2025; 26:e947246
800 1375 0
19 Jul 2025 : Case report 
Adult Hemophagocytic Lymphohistiocytosis (HLH) with Neurological Involvement: Diagnostic Complexities – A Case Report and Literature Review
Michał J. Sekuła , Anna Jamroz-Wiśniewska , Urszula Chyrchel-Paszkiewicz , Aleksandra Pietruczuk , Aleksandra Dembowska , Maciej Dubaj , Karol Bigosiński , Konrad Rejdak
DOI: 10.12659/AJCR.947694
Am J Case Rep 2025; 26:e947694
1,437 1,897 0
19 Jul 2025 : Case report
Adult Hemophagocytic Lymphohistiocytosis (HLH) with Neurological Involvement: Diagnostic Complexities – A Case Report and Literature Review
Michał J. Sekuła , Anna Jamroz-Wiśniewska , Urszula Chyrchel-Paszkiewicz , Aleksandra Pietruczuk , Aleksandra Dembowska , Maciej Dubaj , Karol Bigosiński , Konrad Rejdak
DOI: 10.12659/AJCR.947694
Am J Case Rep 2025; 26:e947694
1437 1897 0
17 Jul 2025 : Case report
Recognizing Exocrine Pancreatic Insufficiency in Patients with Diabetes: A Case Study
Victoria Kusztos , Mariya Pogorelova
DOI: 10.12659/AJCR.948283
Am J Case Rep 2025; 26:e948283
851 1,379 0
17 Jul 2025 : Case report
Recognizing Exocrine Pancreatic Insufficiency in Patients with Diabetes: A Case Study
Victoria Kusztos , Mariya Pogorelova
DOI: 10.12659/AJCR.948283
Am J Case Rep 2025; 26:e948283
851 1379 0
16 Jul 2025 : Case report 
Endovascular Embolization in Acquired Hemophilia A: A Case Study Highlighting Diagnostic and Therapeutic Strategies
Michail Makris, Stavroula Bountola, Vasileios Patriarcheas, Anastasia Adamou , Panagiota Tsiatsiou , Vasileios Perifanis , Christos Savopoulos, Georgia Kaiafa
DOI: 10.12659/AJCR.948268
Am J Case Rep 2025; 26:e948268
933 1,569 0
16 Jul 2025 : Case report
Endovascular Embolization in Acquired Hemophilia A: A Case Study Highlighting Diagnostic and Therapeutic Strategies
Michail Makris, Stavroula Bountola, Vasileios Patriarcheas, Anastasia Adamou , Panagiota Tsiatsiou , Vasileios Perifanis , Christos Savopoulos, Georgia Kaiafa
DOI: 10.12659/AJCR.948268
Am J Case Rep 2025; 26:e948268
933 1569 0
13 Jul 2025 : Case report 
Adult Acute Appendicitis Complicated by Intestinal Malrotation: A Case Analysis
Daniel Krstic , Dimitrios Chatziisaak , Strahinja Konstantinović , Luca Benigno, Christopher Soll, Magdalena Biraima
DOI: 10.12659/AJCR.949194
Am J Case Rep 2025; 26:e949194
781 1,668 0
13 Jul 2025 : Case report
Adult Acute Appendicitis Complicated by Intestinal Malrotation: A Case Analysis
Daniel Krstic , Dimitrios Chatziisaak , Strahinja Konstantinović , Luca Benigno, Christopher Soll, Magdalena Biraima
DOI: 10.12659/AJCR.949194
Am J Case Rep 2025; 26:e949194
781 1668 0
12 Jul 2025 : Case report 
HIV-Negative African American Man with Gastrointestinal Kaposi Sarcoma Associated with Adalimumab Treatment for Cardiac Sarcoidosis: A Case Report
Vaishnavi Ghantasala, Aadi Palvia, Abhiram Rao Damera, Marcela Salomao, Lucinda A. Harris, Jana G. Hashash, Karthik Gnanapandithan
DOI: 10.12659/AJCR.947163
Am J Case Rep 2025; 26:e947163
870 1,677 0
12 Jul 2025 : Case report
HIV-Negative African American Man with Gastrointestinal Kaposi Sarcoma Associated with Adalimumab Treatment for Cardiac Sarcoidosis: A Case Report
Vaishnavi Ghantasala, Aadi Palvia, Abhiram Rao Damera, Marcela Salomao, Lucinda A. Harris, Jana G. Hashash, Karthik Gnanapandithan
DOI: 10.12659/AJCR.947163
Am J Case Rep 2025; 26:e947163
870 1677 0
17 Aug 2025 : Case report
Atypical Presentation of Hereditary ATTR Amyloidosis with Gastrointestinal and Hepatic Manifestations in an 88-Year-Old Woman: A Case Report
Anaiya Singh, Viraj Panchal , Shiva Jashwanth Gaddam, Yousif Barzani, Xiaoming Fan, Kshitij Arora, Rusella Mirza, Terry Lairmore, Poornima Ramadas
DOI: 10.12659/AJCR.947690
Am J Case Rep 2025; 26:e947690
928 946 0
17 Aug 2025 : Case report
Atypical Presentation of Hereditary ATTR Amyloidosis with Gastrointestinal and Hepatic Manifestations in an 88-Year-Old Woman: A Case Report
Anaiya Singh, Viraj Panchal , Shiva Jashwanth Gaddam, Yousif Barzani, Xiaoming Fan, Kshitij Arora, Rusella Mirza, Terry Lairmore, Poornima Ramadas
DOI: 10.12659/AJCR.947690
Am J Case Rep 2025; 26:e947690
928 946 0
08 Jul 2025 : Case report
Distinguishing Jarisch-Herxheimer Reaction From Septic Shock in Leptospirosis Patients: A Case Study
Koma Hotta , Takahiro Maruyama, Takamasa Ito, Takahiro Yonemoto, Shunsuke Kasai, Haruki Imura
DOI: 10.12659/AJCR.947704
Am J Case Rep 2025; 26:e947704
1,163 1,525 0
08 Jul 2025 : Case report
Distinguishing Jarisch-Herxheimer Reaction From Septic Shock in Leptospirosis Patients: A Case Study
Koma Hotta , Takahiro Maruyama, Takamasa Ito, Takahiro Yonemoto, Shunsuke Kasai, Haruki Imura
DOI: 10.12659/AJCR.947704
Am J Case Rep 2025; 26:e947704
1163 1525 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953173
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953192
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.952818
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953608
Most Viewed Current Articles
07 Dec 2021 : Case report
22,364,578
DOI :10.12659/AJCR.934347
Am J Case Rep 2021; 22:e934347
06 Dec 2021 : Case report 
174,245
DOI :10.12659/AJCR.934406
Am J Case Rep 2021; 22:e934406
21 Jun 2024 : Case report
119,744
DOI :10.12659/AJCR.944371
Am J Case Rep 2024; 25:e944371
07 Mar 2024 : Case report
64,648
DOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133