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Challenging differential diagnosis

#947774

12 Dec 2025 : Case report  Romania

Unpredictable Evolution of Pilocytic Astrocytoma in Adults: A Case Series and Diagnostic Challenges

Anamaria Sincu, Cristian-Ionut Orasanu ORCID logo, Raluca Ioana Voda ORCID logo, Madalina Bosoteanu ORCID logo, Manuela Enciu ORCID logo, Sorin Vamesu ORCID logo, Sinziana Andra Ghitoi, Mariana Deacu ORCID logo

DOI: 10.12659/AJCR.947774

Am J Case Rep 2025; 26:e947774

1,023 4,785 0

#947774

12 Dec 2025 : Case report  Romania

Unpredictable Evolution of Pilocytic Astrocytoma in Adults: A Case Series and Diagnostic Challenges

Anamaria Sincu, Cristian-Ionut Orasanu ORCID logo, Raluca Ioana Voda ORCID logo, Madalina Bosoteanu ORCID logo, Manuela Enciu ORCID logo, Sorin Vamesu ORCID logo, Sinziana Andra Ghitoi, Mariana Deacu ORCID logo

DOI: 10.12659/AJCR.947774

Am J Case Rep 2025; 26:e947774

1023 4785 0

#949936

14 Dec 2025 : Case report  Saudi Arabia

Bruton’s Agammaglobulinemia: Case Series and Literature Review From King Fahad Central Hospital, Jizan, Saudi Arabia

Ahmed Shamakhi, Nabil Dhayhi, Shatha Matabi, Manal Maashi, Abdullah Dhaifallah Hamdi, Bander Ali, Fadhel Hazazi, Abdullah H. Alhamoud

DOI: 10.12659/AJCR.949936

Am J Case Rep 2025; 26:e949936

1,122 3,279 0

#949936

14 Dec 2025 : Case report  Saudi Arabia

Bruton’s Agammaglobulinemia: Case Series and Literature Review From King Fahad Central Hospital, Jizan, Saudi Arabia

Ahmed Shamakhi, Nabil Dhayhi, Shatha Matabi, Manal Maashi, Abdullah Dhaifallah Hamdi, Bander Ali, Fadhel Hazazi, Abdullah H. Alhamoud

DOI: 10.12659/AJCR.949936

Am J Case Rep 2025; 26:e949936

1122 3279 0

#948020

11 Dec 2025 : Case report  Poland

A 60-Year-Old Man with an Incidental Finding of an Asymptomatic Aneurysm of the Right Gastroepiploic Artery Managed by Laparoscopic Resection

Maksymilian Baryła ORCID logo, Paweł Kazimierz Ziemiański ORCID logo

DOI: 10.12659/AJCR.948020

Am J Case Rep 2025; 26:e948020

766 1,163 0

#948020

11 Dec 2025 : Case report  Poland

A 60-Year-Old Man with an Incidental Finding of an Asymptomatic Aneurysm of the Right Gastroepiploic Artery Managed by Laparoscopic Resection

Maksymilian Baryła ORCID logo, Paweł Kazimierz Ziemiański ORCID logo

DOI: 10.12659/AJCR.948020

Am J Case Rep 2025; 26:e948020

766 1163 0

#950444

30 Nov 2025 : Case report  USA

Afebrile HSV-2 Encephalitis with Radiographic Atypia and Minimal Systemic Inflammation: A Case Report

Shunsuke Kondo ORCID logo, Wejdan Abo Qayas, Osama Hasan, Rachel Haide N. Tacata, Matthew W. Kobylinski, Lorrance Majewski

DOI: 10.12659/AJCR.950444

Am J Case Rep 2025; 26:e950444

882 2,479 0

#950444

30 Nov 2025 : Case report  USA

Afebrile HSV-2 Encephalitis with Radiographic Atypia and Minimal Systemic Inflammation: A Case Report

Shunsuke Kondo ORCID logo, Wejdan Abo Qayas, Osama Hasan, Rachel Haide N. Tacata, Matthew W. Kobylinski, Lorrance Majewski

DOI: 10.12659/AJCR.950444

Am J Case Rep 2025; 26:e950444

882 2479 0

#949363

07 Dec 2025 : Case report  Canada

Campfire Smoke as a Plausible Trigger for Vasospastic Angina: Insights From a Case Report

Gabrielle Denault, Anne-Sophie Lê, Emad Tahir, Stéphane Perron

DOI: 10.12659/AJCR.949363

Am J Case Rep 2025; 26:e949363

953 3,346 0

#949363

07 Dec 2025 : Case report  Canada

Campfire Smoke as a Plausible Trigger for Vasospastic Angina: Insights From a Case Report

Gabrielle Denault, Anne-Sophie Lê, Emad Tahir, Stéphane Perron

DOI: 10.12659/AJCR.949363

Am J Case Rep 2025; 26:e949363

953 3346 0

#949587

10 Dec 2025 : Case report  Palestinian Territory, Occupied

Isolated Transient Neonatal Ascites in a Preterm Infant Born to a Mother with Mirror Syndrome: A Case Report

Mo’ath Abu Hamdeh, Rasmea Mohammad Asad, Zeidan Abdalsalam, Mohammad Maraqah, Lema Saleh Khaled Jaber, Mai M.R. Rostom, Majed Methqal Abu Jaish

DOI: 10.12659/AJCR.949587

Am J Case Rep 2025; 26:e949587

972 2,244 0

#949587

10 Dec 2025 : Case report  Palestinian Territory, Occupied

Isolated Transient Neonatal Ascites in a Preterm Infant Born to a Mother with Mirror Syndrome: A Case Report

Mo’ath Abu Hamdeh, Rasmea Mohammad Asad, Zeidan Abdalsalam, Mohammad Maraqah, Lema Saleh Khaled Jaber, Mai M.R. Rostom, Majed Methqal Abu Jaish

DOI: 10.12659/AJCR.949587

Am J Case Rep 2025; 26:e949587

972 2244 0

#949004

03 Dec 2025 : Case report  Japan

Endoscopic Retrieval of Ingested Button Battery From a Colonic Diverticulum in an Alzheimer’s Patient: A Case Report

Kazuko Hizukuri, Yasuhiko Fujita, Teruyoshi Amagai

DOI: 10.12659/AJCR.949004

Am J Case Rep 2025; 26:e949004

661 1,181 0

#949004

03 Dec 2025 : Case report  Japan

Endoscopic Retrieval of Ingested Button Battery From a Colonic Diverticulum in an Alzheimer’s Patient: A Case Report

Kazuko Hizukuri, Yasuhiko Fujita, Teruyoshi Amagai

DOI: 10.12659/AJCR.949004

Am J Case Rep 2025; 26:e949004

661 1181 0

#949541

04 Dec 2025 : Case report  Ireland

A 27-Year-Old Man with Chronic Traumatic Pancreatic Fistula Managed with Percutaneous Microwave Ablation

Raphael AlSarma, Abdel-Rahman Salameh, Talal Sultan M. Althobity, Farooq Bacha, Mohamed Karji Almarzooqi, Iyad Hassan

DOI: 10.12659/AJCR.949541

Am J Case Rep 2025; 26:e949541

736 1,273 0

#949541

04 Dec 2025 : Case report  Ireland

A 27-Year-Old Man with Chronic Traumatic Pancreatic Fistula Managed with Percutaneous Microwave Ablation

Raphael AlSarma, Abdel-Rahman Salameh, Talal Sultan M. Althobity, Farooq Bacha, Mohamed Karji Almarzooqi, Iyad Hassan

DOI: 10.12659/AJCR.949541

Am J Case Rep 2025; 26:e949541

736 1273 0

#949941

01 Dec 2025 : Case report  Japan

Late-Onset Mesh Infection 10 Years After Right Inguinal Hernia Repair: A Case Report

Ryoichi Shimizu ORCID logo, Masahito Uji, Hideo Matsubara, Yasutomo Miura, Yudai Aoki, Takahiro Maehata, Kazumasa Matsuoka, Yasuji Mokuno

DOI: 10.12659/AJCR.949941

Am J Case Rep 2025; 26:e949941

894 3,970 0

#949941

01 Dec 2025 : Case report  Japan

Late-Onset Mesh Infection 10 Years After Right Inguinal Hernia Repair: A Case Report

Ryoichi Shimizu ORCID logo, Masahito Uji, Hideo Matsubara, Yasutomo Miura, Yudai Aoki, Takahiro Maehata, Kazumasa Matsuoka, Yasuji Mokuno

DOI: 10.12659/AJCR.949941

Am J Case Rep 2025; 26:e949941

894 3970 0

#949018

09 Dec 2025 : Case report  China

A Rare Case of Emphysematous Pyelonephritis Following Retrograde Intrarenal Surgery in an Elderly Man

Weiyong Zhong ORCID logo, Feihong Xu ORCID logo, Shujiang Ye, Yu Liu, Wei Zhao, Zhenquan Lu, Lin Xiong, Xiang Xu

DOI: 10.12659/AJCR.949018

Am J Case Rep 2025; 26:e949018

779 1,359 0

#949018

09 Dec 2025 : Case report  China

A Rare Case of Emphysematous Pyelonephritis Following Retrograde Intrarenal Surgery in an Elderly Man

Weiyong Zhong ORCID logo, Feihong Xu ORCID logo, Shujiang Ye, Yu Liu, Wei Zhao, Zhenquan Lu, Lin Xiong, Xiang Xu

DOI: 10.12659/AJCR.949018

Am J Case Rep 2025; 26:e949018

779 1359 0

#949597

29 Nov 2025 : Case report  Greece

Mixed Cryoglobulinemia in the Setting of Monoclonal B-Cell Lymphocytosis and Monoclonal Gammopathy of Unknown Significance: A Case Report

Eleni Bouziani ORCID logo, Luisa Ladel, Aaron James Stonestrom ORCID logo

DOI: 10.12659/AJCR.949597

Am J Case Rep 2025; 26:e949597

877 2,178 0

#949597

29 Nov 2025 : Case report  Greece

Mixed Cryoglobulinemia in the Setting of Monoclonal B-Cell Lymphocytosis and Monoclonal Gammopathy of Unknown Significance: A Case Report

Eleni Bouziani ORCID logo, Luisa Ladel, Aaron James Stonestrom ORCID logo

DOI: 10.12659/AJCR.949597

Am J Case Rep 2025; 26:e949597

877 2178 0

#949913

07 Dec 2025 : Case report  Thailand

Acute Kidney Injury from Mononuclear Cell-Predominated Interstitial Nephritis After Introduction of a Glucagon-Like Peptide-1 Receptor Agonist: A Case Report

Raweekarn Itsathitpaisarn, Nattavong Suksawad, Watsapol Wongwikrom, Jerasit Surintrspanont ORCID logo, Thana Thongsricome ORCID logo

DOI: 10.12659/AJCR.949913

Am J Case Rep 2025; 26:e949913

1,102 2,494 0

#949913

07 Dec 2025 : Case report  Thailand

Acute Kidney Injury from Mononuclear Cell-Predominated Interstitial Nephritis After Introduction of a Glucagon-Like Peptide-1 Receptor Agonist: A Case Report

Raweekarn Itsathitpaisarn, Nattavong Suksawad, Watsapol Wongwikrom, Jerasit Surintrspanont ORCID logo, Thana Thongsricome ORCID logo

DOI: 10.12659/AJCR.949913

Am J Case Rep 2025; 26:e949913

1102 2494 0

#949699

09 Dec 2025 : Case report  Indonesia

Behçet Disease and Cognitive Impairment: A Case Study of an Overlooked Symptom

Caroline Evanthe Nathania ORCID logo, Astuti Prodjohardjono ORCID logo, Noor Alia Susianti ORCID logo, Abdul Gofir ORCID logo, Cempaka Thursina Srie Setyaningrum ORCID logo, Kamala Kan Nur Azza ORCID logo, Ahmad Asmedi ORCID logo, Sri Sutarni ORCID logo

DOI: 10.12659/AJCR.949699

Am J Case Rep 2025; 26:e949699

1,062 2,605 0

#949699

09 Dec 2025 : Case report  Indonesia

Behçet Disease and Cognitive Impairment: A Case Study of an Overlooked Symptom

Caroline Evanthe Nathania ORCID logo, Astuti Prodjohardjono ORCID logo, Noor Alia Susianti ORCID logo, Abdul Gofir ORCID logo, Cempaka Thursina Srie Setyaningrum ORCID logo, Kamala Kan Nur Azza ORCID logo, Ahmad Asmedi ORCID logo, Sri Sutarni ORCID logo

DOI: 10.12659/AJCR.949699

Am J Case Rep 2025; 26:e949699

1062 2605 0

#949421

30 Nov 2025 : Case report  China

Improvement of Renal Function in Atrial Fibrillation Patients via Catheter Ablation and Left Atrial Appendage Closure: A Case Report

Jiaying Chen, Caiyun Li, Yuegang Wang, Hongzeng Xu

DOI: 10.12659/AJCR.949421

Am J Case Rep 2025; 26:e949421

1,003 2,348 0

#949421

30 Nov 2025 : Case report  China

Improvement of Renal Function in Atrial Fibrillation Patients via Catheter Ablation and Left Atrial Appendage Closure: A Case Report

Jiaying Chen, Caiyun Li, Yuegang Wang, Hongzeng Xu

DOI: 10.12659/AJCR.949421

Am J Case Rep 2025; 26:e949421

1003 2348 0

#949379

06 Dec 2025 : Case report  Puerto Rico

Severe Hemoperitoneum From a Ruptured Ovarian Cyst in a Patient with Antiphospholipid Syndrome and Antithrombin III Deficiency: A Case Report

Adrian A. Naoun ORCID logo, Max Ramírez Vázquez, Yandy García Martin, Raysa D. López Torres, Ernesto Garcia Santiago

DOI: 10.12659/AJCR.949379

Am J Case Rep 2025; 26:e949379

1,352 4,211 0

#949379

06 Dec 2025 : Case report  Puerto Rico

Severe Hemoperitoneum From a Ruptured Ovarian Cyst in a Patient with Antiphospholipid Syndrome and Antithrombin III Deficiency: A Case Report

Adrian A. Naoun ORCID logo, Max Ramírez Vázquez, Yandy García Martin, Raysa D. López Torres, Ernesto Garcia Santiago

DOI: 10.12659/AJCR.949379

Am J Case Rep 2025; 26:e949379

1352 4211 0

#948797

03 Nov 2025 : Case report  Saudi Arabia

Novel PGM1 Mutation in Congenital Disorder of Glycosylation Type 1T: A Case Report of Liver Failure and Myopathy

Abdulaziz A. Al-Ahmari

DOI: 10.12659/AJCR.948797

Am J Case Rep 2025; 26:e948797

813 2,007 0

#948797

03 Nov 2025 : Case report  Saudi Arabia

Novel PGM1 Mutation in Congenital Disorder of Glycosylation Type 1T: A Case Report of Liver Failure and Myopathy

Abdulaziz A. Al-Ahmari

DOI: 10.12659/AJCR.948797

Am J Case Rep 2025; 26:e948797

813 2007 0

#950906

28 Nov 2025 : Case report  Switzerland

Unexpected Schistosomiasis Diagnosed After Appendectomy in a Migrant Child

Isshak Mrabet-Deraoui ORCID logo, Lorenzo Monforte ORCID logo, Slobodan Prica ORCID logo, Yvonne Schmiedel ORCID logo

DOI: 10.12659/AJCR.950906

Am J Case Rep 2025; 26:e950906

815 1,523 0

#950906

28 Nov 2025 : Case report  Switzerland

Unexpected Schistosomiasis Diagnosed After Appendectomy in a Migrant Child

Isshak Mrabet-Deraoui ORCID logo, Lorenzo Monforte ORCID logo, Slobodan Prica ORCID logo, Yvonne Schmiedel ORCID logo

DOI: 10.12659/AJCR.950906

Am J Case Rep 2025; 26:e950906

815 1523 0

#950268

31 Oct 2025 : Case report  Ecuador

Apical Hypertrophic Cardiomyopathy: Diagnostic Challenges in a Patient with Hypertension and Obstructive Sleep Apnea

Jordan Llerena-Velastegui ORCID logo, Daniela Benitez-Gutierrez, Diego Benitez-Zapata, Camila Escobar-Andrade, Daniela Corral-Hidalgo

DOI: 10.12659/AJCR.950268

Am J Case Rep 2025; 26:e950268

871 2,931 0

#950268

31 Oct 2025 : Case report  Ecuador

Apical Hypertrophic Cardiomyopathy: Diagnostic Challenges in a Patient with Hypertension and Obstructive Sleep Apnea

Jordan Llerena-Velastegui ORCID logo, Daniela Benitez-Gutierrez, Diego Benitez-Zapata, Camila Escobar-Andrade, Daniela Corral-Hidalgo

DOI: 10.12659/AJCR.950268

Am J Case Rep 2025; 26:e950268

871 2931 0

#950781

06 Dec 2025 : Case report  Saudi Arabia

Acute Kidney Injury After Accelerated Dosing of Tirzepatide in a Patient with Multiple Comorbidities: A Case Report

Abdulelah H. Almansour ORCID logo

DOI: 10.12659/AJCR.950781

Am J Case Rep 2025; 26:e950781

1,521 12,674 0

#950781

06 Dec 2025 : Case report  Saudi Arabia

Acute Kidney Injury After Accelerated Dosing of Tirzepatide in a Patient with Multiple Comorbidities: A Case Report

Abdulelah H. Almansour ORCID logo

DOI: 10.12659/AJCR.950781

Am J Case Rep 2025; 26:e950781

1521 12674 0

#950405

02 Dec 2025 : Case report  Lebanon

Neuropsychiatric Symptoms After HHV-6 Encephalitis in an Immunocompetent Child: A Case Report

Dima Habanjar, Samah Trad, Daniel Charouf, Siham Kreidly, Rose-Mary Boustany ORCID logo

DOI: 10.12659/AJCR.950405

Am J Case Rep 2025; 26:e950405

1,041 3,233 0

#950405

02 Dec 2025 : Case report  Lebanon

Neuropsychiatric Symptoms After HHV-6 Encephalitis in an Immunocompetent Child: A Case Report

Dima Habanjar, Samah Trad, Daniel Charouf, Siham Kreidly, Rose-Mary Boustany ORCID logo

DOI: 10.12659/AJCR.950405

Am J Case Rep 2025; 26:e950405

1041 3233 0

#948800

27 Nov 2025 : Case report  Yemen

Combining Minimally Invasive Mitral Valve Replacement with Kidney Transplantation: A Pioneering Case

Abudar Al Ganadi, Ismail Al-Shameri, Nabeel Mughallis, Naseem Al-Wsabi

DOI: 10.12659/AJCR.948800

Am J Case Rep 2025; 26:e948800

1,497 1,566 0

#948800

27 Nov 2025 : Case report  Yemen

Combining Minimally Invasive Mitral Valve Replacement with Kidney Transplantation: A Pioneering Case

Abudar Al Ganadi, Ismail Al-Shameri, Nabeel Mughallis, Naseem Al-Wsabi

DOI: 10.12659/AJCR.948800

Am J Case Rep 2025; 26:e948800

1497 1566 0

#950045

01 Nov 2025 : Case report  USA

Post-COVID-19-Associated Asymptomatic Sarcoidosis with Hypercalcemia and Renal Dysfunction: A Case Report and Literature Review

Mrudula Thiriveedi ORCID logo, Hersh Patel, Caitlin Curran, Siddharth Patel ORCID logo, Sujatha Baddam ORCID logo, Rafik ElBeblawy, Punuru J. Reddy

DOI: 10.12659/AJCR.950045

Am J Case Rep 2025; 26:e950045

951 2,762 0

#950045

01 Nov 2025 : Case report  USA

Post-COVID-19-Associated Asymptomatic Sarcoidosis with Hypercalcemia and Renal Dysfunction: A Case Report and Literature Review

Mrudula Thiriveedi ORCID logo, Hersh Patel, Caitlin Curran, Siddharth Patel ORCID logo, Sujatha Baddam ORCID logo, Rafik ElBeblawy, Punuru J. Reddy

DOI: 10.12659/AJCR.950045

Am J Case Rep 2025; 26:e950045

951 2762 0

#949805

05 Dec 2025 : Case report  China

Surgical Decompression in a 32-Year-Old Man with Chronic Onset of Thoracic Spontaneous Spinal Epidural Hematoma: A Case Report

Xi Xiang, Jie Wang, Han Wang, Qi Yang, Xun Sun, Shiyu Li, Lili Zou

DOI: 10.12659/AJCR.949805

Am J Case Rep 2025; 26:e949805

791 1,551 0

#949805

05 Dec 2025 : Case report  China

Surgical Decompression in a 32-Year-Old Man with Chronic Onset of Thoracic Spontaneous Spinal Epidural Hematoma: A Case Report

Xi Xiang, Jie Wang, Han Wang, Qi Yang, Xun Sun, Shiyu Li, Lili Zou

DOI: 10.12659/AJCR.949805

Am J Case Rep 2025; 26:e949805

791 1551 0

#949019

18 Nov 2025 : Case report  Switzerland

Exploring Maralixibat for Treatment-Resistant Pruritus in Intrahepatic Cholestasis of Pregnancy and Primary Biliary Cholangitis: A Case Report

Lara Alexandra Bersuch ORCID logo, Andrea De Gottardi ORCID logo

DOI: 10.12659/AJCR.949019

Am J Case Rep 2025; 26:e949019

1,130 2,741 0

#949019

18 Nov 2025 : Case report  Switzerland

Exploring Maralixibat for Treatment-Resistant Pruritus in Intrahepatic Cholestasis of Pregnancy and Primary Biliary Cholangitis: A Case Report

Lara Alexandra Bersuch ORCID logo, Andrea De Gottardi ORCID logo

DOI: 10.12659/AJCR.949019

Am J Case Rep 2025; 26:e949019

1130 2741 0

#948856

17 Nov 2025 : Case report  Israel

Sclerosing Cholangitis and Multiple Liver Abscesses in a Patient with Thymoma, Myasthenia Gravis, and Immune Deficiency (Good’s Syndrome)

Shaul Yaari, Joshua Stokar ORCID logo, Yehonatan Bar Moshe, Nurith Hiller, Elena Zuckerman, Samuel N. Heyman

DOI: 10.12659/AJCR.948856

Am J Case Rep 2025; 26:e948856

802 1,294 0

#948856

17 Nov 2025 : Case report  Israel

Sclerosing Cholangitis and Multiple Liver Abscesses in a Patient with Thymoma, Myasthenia Gravis, and Immune Deficiency (Good’s Syndrome)

Shaul Yaari, Joshua Stokar ORCID logo, Yehonatan Bar Moshe, Nurith Hiller, Elena Zuckerman, Samuel N. Heyman

DOI: 10.12659/AJCR.948856

Am J Case Rep 2025; 26:e948856

802 1294 0

In Press

Case report  USA

Refractory Hyperammonemic Encephalopathy as a Paraneoplastic Presentation of Fibrolamellar Hepatocellular C...

Am J Case Rep In Press; DOI: 10.12659/AJCR.952819  

Case report  Indonesia

Ovarian Lymphoma and Bone Metastasis Presenting With Paraparesis in an Adolescent: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.952834  

Case report  France

Pilomatricoma in an Octogenarian: A Case Report of an Exceptional Late-Life Presentation

Am J Case Rep In Press; DOI: 10.12659/AJCR.953320  

Case report  USA

Canine-Associated Capnocytophaga canimorsus Bacteremia in an Older Adult Without Classical Immunosuppressiv...

Am J Case Rep In Press; DOI: 10.12659/AJCR.952980  

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923