Challenging differential diagnosis

04 Jan 2026 : Case report
Effective Management of a Rare Case of Pediatric ANCA-Associated Vasculitis With Rituximab and Mycophenolate Mofetil
Yi Fang, Ali Kurady, Faris Q. Hashim, Blaine Berger, Arundhati Rao
DOI: 10.12659/AJCR.949274
Am J Case Rep 2026; 27:e949274
909 2,213 0

04 Jan 2026 : Case report
Effective Management of a Rare Case of Pediatric ANCA-Associated Vasculitis With Rituximab and Mycophenolate Mofetil
Yi Fang, Ali Kurady, Faris Q. Hashim, Blaine Berger, Arundhati Rao
DOI: 10.12659/AJCR.949274
Am J Case Rep 2026; 27:e949274
909 2213 0

08 Jan 2026 : Case report
Diagnostic Challenges in Atypical Hemolytic Uremic Syndrome: A Case of Artificial Mitral Valve Dysfunction as a Possible Trigger for Severe Thrombotic Microangiopathy
Gabriela Kot
, Agata Wróbel
, Błażej Kieszek
, Zbigniew Sablik
, Michał Nowicki
DOI: 10.12659/AJCR.948516
Am J Case Rep 2026; 27:e948516
860 1,181 0

08 Jan 2026 : Case report
Diagnostic Challenges in Atypical Hemolytic Uremic Syndrome: A Case of Artificial Mitral Valve Dysfunction as a Possible Trigger for Severe Thrombotic Microangiopathy
Gabriela Kot
, Agata Wróbel
, Błażej Kieszek
, Zbigniew Sablik
, Michał Nowicki
DOI: 10.12659/AJCR.948516
Am J Case Rep 2026; 27:e948516
860 1181 0

07 Jan 2026 : Case report
Fampridine in Hereditary Spastic Paraplegia Type 4 With SPAST Variant c.683-2A>C: A Case Report
DOI: 10.12659/AJCR.951160
Am J Case Rep 2026; 27:e951160
646 1,423 0

07 Jan 2026 : Case report
Fampridine in Hereditary Spastic Paraplegia Type 4 With SPAST Variant c.683-2A>C: A Case Report
DOI: 10.12659/AJCR.951160
Am J Case Rep 2026; 27:e951160
646 1423 0

05 Jan 2026 : Case report
Healing Beyond the Operating Room: Bedside Strategies for Necrotizing Fasciitis
Gabriela Kot
, Łukasz Świątek
, Tomasz Banasiewicz
DOI: 10.12659/AJCR.949754
Am J Case Rep 2026; 27:e949754
695 1,769 0

05 Jan 2026 : Case report
Healing Beyond the Operating Room: Bedside Strategies for Necrotizing Fasciitis
Gabriela Kot
, Łukasz Świątek
, Tomasz Banasiewicz
DOI: 10.12659/AJCR.949754
Am J Case Rep 2026; 27:e949754
695 1769 0

06 Jan 2026 : Case report
Rehabilitation of Lower Limb Motor Dysfunction and Neurogenic Bladder After Low-Dose Chlorfenapyr Poisoning With Delayed Rhabdomyolysis: A Case Report
Beibei Hou, Mingru Huang
, Xinwei Tang, Shan Tian, Gang Liu, Junfa Wu, Yi Wu, Hongyu Xie
DOI: 10.12659/AJCR.949455
Am J Case Rep 2026; 27:e949455
952 1,269 0

06 Jan 2026 : Case report
Rehabilitation of Lower Limb Motor Dysfunction and Neurogenic Bladder After Low-Dose Chlorfenapyr Poisoning With Delayed Rhabdomyolysis: A Case Report
Beibei Hou, Mingru Huang
, Xinwei Tang, Shan Tian, Gang Liu, Junfa Wu, Yi Wu, Hongyu Xie
DOI: 10.12659/AJCR.949455
Am J Case Rep 2026; 27:e949455
952 1269 0

30 Dec 2025 : Case report
Beyond CKD-Associated Pruritus: Paraneoplastic Itch Revealing CLL/SLL in ESRD: A Case Report
Julia Kacperczyk
, Monika Dąbek, Agnieszka Makówka
, Michał Nowicki
DOI: 10.12659/AJCR.949787
Am J Case Rep 2025; 26:e949787
866 1,471 0

30 Dec 2025 : Case report
Beyond CKD-Associated Pruritus: Paraneoplastic Itch Revealing CLL/SLL in ESRD: A Case Report
Julia Kacperczyk
, Monika Dąbek, Agnieszka Makówka
, Michał Nowicki
DOI: 10.12659/AJCR.949787
Am J Case Rep 2025; 26:e949787
866 1471 0

05 Jan 2026 : Case report
A 67-Year-Old Man With Hypertension Presenting With Spontaneous Rupture of a Large Splenic Artery Aneurysm Associated With Thrombus
Rakia Siala, Mohamed Ali Mseddi
, Chaima Yakoubi
, Alia Zehani, Hajer Hassine, Meriem Hsairi
, Rami Guizani
, Hela Kchir
, Karim Sassi, Mohamed Ben Slima
DOI: 10.12659/AJCR.950099
Am J Case Rep 2026; 27:e950099
833 1,381 0

05 Jan 2026 : Case report
A 67-Year-Old Man With Hypertension Presenting With Spontaneous Rupture of a Large Splenic Artery Aneurysm Associated With Thrombus
Rakia Siala, Mohamed Ali Mseddi
, Chaima Yakoubi
, Alia Zehani, Hajer Hassine, Meriem Hsairi
, Rami Guizani
, Hela Kchir
, Karim Sassi, Mohamed Ben Slima
DOI: 10.12659/AJCR.950099
Am J Case Rep 2026; 27:e950099
833 1381 0

01 Jan 2026 : Case report
Twisted Mystery: Identifying Gallbladder Volvulus: Challenges in Preoperative Diagnosis
Yahya Al-Habbal, Ayman M. Al-Qaaneh
, Adnan A. Al Aloul, Sami Lazkani, Afnan Alghnaimat
DOI: 10.12659/AJCR.949283
Am J Case Rep 2026; 27:e949283
1,044 169 0

01 Jan 2026 : Case report
Twisted Mystery: Identifying Gallbladder Volvulus: Challenges in Preoperative Diagnosis
Yahya Al-Habbal, Ayman M. Al-Qaaneh
, Adnan A. Al Aloul, Sami Lazkani, Afnan Alghnaimat
DOI: 10.12659/AJCR.949283
Am J Case Rep 2026; 27:e949283
1044 169 0

04 Jan 2026 : Case report
Peritoneal Post-Radiation Angiosarcoma in a Patient With a History of Radiation for Cervical Cancer
Xuan-Fang Qian, Xia-Wan Wang, He-Qing Yi, Lin-Fa Li
DOI: 10.12659/AJCR.949701
Am J Case Rep 2026; 27:e949701
740 1,082 0

04 Jan 2026 : Case report
Peritoneal Post-Radiation Angiosarcoma in a Patient With a History of Radiation for Cervical Cancer
Xuan-Fang Qian, Xia-Wan Wang, He-Qing Yi, Lin-Fa Li
DOI: 10.12659/AJCR.949701
Am J Case Rep 2026; 27:e949701
740 1082 0

02 Jan 2026 : Case report
Multidisciplinary Management and Anesthesia Considerations for Diabetic Ketoacidosis With Hypertriglyceridemic Acute Pancreatitis in Pregnancy: A Case Report
Peiting Liu, Tao Li, Suquan Yu, Fan Liu, Lanji Huang
DOI: 10.12659/AJCR.949837
Am J Case Rep 2026; 27:e949837
1,107 103 0

02 Jan 2026 : Case report
Multidisciplinary Management and Anesthesia Considerations for Diabetic Ketoacidosis With Hypertriglyceridemic Acute Pancreatitis in Pregnancy: A Case Report
Peiting Liu, Tao Li, Suquan Yu, Fan Liu, Lanji Huang
DOI: 10.12659/AJCR.949837
Am J Case Rep 2026; 27:e949837
1107 103 0

27 Nov 2025 : Case report
Gastric Bipartition with Functional Duodenum Exclusion (GBp-FDE) as a Possible Surgical Conversion of Sleeve Gastrectomy in Patients with De Novo GERD and Obesity Recidivism: Preliminary Results of a Case Series
Victor Ramos Mussa Dib
, Carlos Augusto Scussel Madalosso
, Paulo Reis Rizzo Esselin De Melo
, Almino Cardoso Ramos
, Luiz Alfredo Vieira D'Almeida
, Luciano Antozzi
, José María Balibrea del Castillo
, Patrick Noel
, Manoel Passos Galvão Neto
, Sonja Chiappetta
, Fernando de Barros
, André Teixeira
, Elinton Adami Chaim
, Ricardo Zorron
, Eudes Paiva de Godoy
, Caio Gustavo Gaspar de Aquino
, Giorgio Alfredo Pedroso Baretta
, Diogo Swain Kfouri
, Hiroji Okano Júnior
, Nilton Tokio Kawahara
, Augusto Cláudio de Almeida Tinoco
, Nicholas Tavares Kruel
, Joe Joaquim Waltrick Junior, Carlos Frota Dillenburg
, Félix Antônio Insaurriaga Dos Santos
, Rafael Antoniazzi Abaid
, Carlos Eduardo Alves Da Costa
, Gabriela Trentin Scortegagna
, Geovana F. Silva
, Halit Eren Taskin
, Ricardo M. Nassar
, Laurent Abram Layani
, Daniel Oscar Caiña
, Manuel Aceves Avalos
, Jorge Bravo Lópes
, José Sergio Verboonen Sotelo
, Ramon Vilallonga Puy
, Christine Karolina Stier
, Carlos Eduardo Domene
, Paula Volpe
, Amador García Ruiz de Gordejuela
, Luis Poggi
, Antônio Torres
, Miguel Ángel Carbajo
, Italo Braghetto
, Rui Ribeiro
, Chetan Parmar
DOI: 10.12659/AJCR.950798
Am J Case Rep 2025; 26:e950798
1,041 1,937 0

27 Nov 2025 : Case report
Gastric Bipartition with Functional Duodenum Exclusion (GBp-FDE) as a Possible Surgical Conversion of Sleeve Gastrectomy in Patients with De Novo GERD and Obesity Recidivism: Preliminary Results of a Case Series
Victor Ramos Mussa Dib
, Carlos Augusto Scussel Madalosso
, Paulo Reis Rizzo Esselin De Melo
, Almino Cardoso Ramos
, Luiz Alfredo Vieira D'Almeida
, Luciano Antozzi
, José María Balibrea del Castillo
, Patrick Noel
, Manoel Passos Galvão Neto
, Sonja Chiappetta
, Fernando de Barros
, André Teixeira
, Elinton Adami Chaim
, Ricardo Zorron
, Eudes Paiva de Godoy
, Caio Gustavo Gaspar de Aquino
, Giorgio Alfredo Pedroso Baretta
, Diogo Swain Kfouri
, Hiroji Okano Júnior
, Nilton Tokio Kawahara
, Augusto Cláudio de Almeida Tinoco
, Nicholas Tavares Kruel
, Joe Joaquim Waltrick Junior, Carlos Frota Dillenburg
, Félix Antônio Insaurriaga Dos Santos
, Rafael Antoniazzi Abaid
, Carlos Eduardo Alves Da Costa
, Gabriela Trentin Scortegagna
, Geovana F. Silva
, Halit Eren Taskin
, Ricardo M. Nassar
, Laurent Abram Layani
, Daniel Oscar Caiña
, Manuel Aceves Avalos
, Jorge Bravo Lópes
, José Sergio Verboonen Sotelo
, Ramon Vilallonga Puy
, Christine Karolina Stier
, Carlos Eduardo Domene
, Paula Volpe
, Amador García Ruiz de Gordejuela
, Luis Poggi
, Antônio Torres
, Miguel Ángel Carbajo
, Italo Braghetto
, Rui Ribeiro
, Chetan Parmar
DOI: 10.12659/AJCR.950798
Am J Case Rep 2025; 26:e950798
1041 1937 0

29 Dec 2025 : Case report
Rapidly Progressive Disseminated Bacillus Calmette-Guérin Infection (BCGitis) in a 3-Month-Old Infant Without Immunodeficiency: A Case Report
Nathalya Queiroz Perillo, Taynara Heliodoro
, Leandro Azevedo De Camargo, Melissa Ameloti Gomes Avelino, Fayez Bahmad Jr.
DOI: 10.12659/AJCR.949742
Am J Case Rep 2025; 26:e949742
687 1,633 0

29 Dec 2025 : Case report
Rapidly Progressive Disseminated Bacillus Calmette-Guérin Infection (BCGitis) in a 3-Month-Old Infant Without Immunodeficiency: A Case Report
Nathalya Queiroz Perillo, Taynara Heliodoro
, Leandro Azevedo De Camargo, Melissa Ameloti Gomes Avelino, Fayez Bahmad Jr.
DOI: 10.12659/AJCR.949742
Am J Case Rep 2025; 26:e949742
687 1633 0

23 Dec 2025 : Case report
Low-Grade Appendiceal Mucinous Neoplasm as an Incidental Finding During Cesarean Section: A Case Report
Vesna Paunovic
, Tomislav Paunovic, Aleksa Jokic
, Bojana S. Ivic
, Aleksandra Petrovic, Nina Pejic
, Milos Stulic
, Jelena Martinov Nestorov, Jovan Jevtic
, Zeljko Vlaisavljevic
DOI: 10.12659/AJCR.949554
Am J Case Rep 2025; 26:e949554
947 2,071 0

23 Dec 2025 : Case report
Low-Grade Appendiceal Mucinous Neoplasm as an Incidental Finding During Cesarean Section: A Case Report
Vesna Paunovic
, Tomislav Paunovic, Aleksa Jokic
, Bojana S. Ivic
, Aleksandra Petrovic, Nina Pejic
, Milos Stulic
, Jelena Martinov Nestorov, Jovan Jevtic
, Zeljko Vlaisavljevic
DOI: 10.12659/AJCR.949554
Am J Case Rep 2025; 26:e949554
947 2071 0

26 Dec 2025 : Case report
Primary Well-Differentiated Neuroendocrine Tumor of the Breast: A Case Report and Literature Review
Sanjna Sai Gudena, Nilesh Digvijay Kashikar, Matthew Charles Wakefield
DOI: 10.12659/AJCR.950684
Am J Case Rep 2025; 26:e950684
692 1,948 0

26 Dec 2025 : Case report
Primary Well-Differentiated Neuroendocrine Tumor of the Breast: A Case Report and Literature Review
Sanjna Sai Gudena, Nilesh Digvijay Kashikar, Matthew Charles Wakefield
DOI: 10.12659/AJCR.950684
Am J Case Rep 2025; 26:e950684
692 1948 0

27 Dec 2025 : Case report
In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Features of Corneal Pseudodendritic Lesions in Hereditary Tyrosinemia Type 1
Rocco Bruno
, Sarah Donatelli, Leonardo Mastropasqua
, Mario Nubile
DOI: 10.12659/AJCR.949591
Am J Case Rep 2025; 26:e949591
668 1,011 0

27 Dec 2025 : Case report
In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Features of Corneal Pseudodendritic Lesions in Hereditary Tyrosinemia Type 1
Rocco Bruno
, Sarah Donatelli, Leonardo Mastropasqua
, Mario Nubile
DOI: 10.12659/AJCR.949591
Am J Case Rep 2025; 26:e949591
668 1011 0

24 Dec 2025 : Case report
Bronchial Arteriovenous Malformation Detection Prior to Catheter Ablation for Paroxysmal Atrial Flutter and Fibrillation: A Case Report
Alexandra Arvanitaki
, Marios Georgios Bantidos
, Theodora Zaglavara
, Lydia Kalogeropoulou
, Athanasios Samaras
, Athina Nasoufidou
, Efstratios Karagiannidis
, Georgios Stavropoulos
, Apostolos Tzikas
, Nikolaos Fragakis
DOI: 10.12659/AJCR.949879
Am J Case Rep 2025; 26:e949879
748 1,288 0

24 Dec 2025 : Case report
Bronchial Arteriovenous Malformation Detection Prior to Catheter Ablation for Paroxysmal Atrial Flutter and Fibrillation: A Case Report
Alexandra Arvanitaki
, Marios Georgios Bantidos
, Theodora Zaglavara
, Lydia Kalogeropoulou
, Athanasios Samaras
, Athina Nasoufidou
, Efstratios Karagiannidis
, Georgios Stavropoulos
, Apostolos Tzikas
, Nikolaos Fragakis
DOI: 10.12659/AJCR.949879
Am J Case Rep 2025; 26:e949879
748 1288 0

25 Dec 2025 : Case report
The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia
Moath Fateh
, Tariq Albweitel, Ahmad Odeh, Sarah Ghaith
DOI: 10.12659/AJCR.950626
Am J Case Rep 2025; 26:e950626
831 2,986 0

25 Dec 2025 : Case report
The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia
Moath Fateh
, Tariq Albweitel, Ahmad Odeh, Sarah Ghaith
DOI: 10.12659/AJCR.950626
Am J Case Rep 2025; 26:e950626
831 2986 0

20 Dec 2025 : Case report
Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment
Ugo Françoise
, Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle
, Paul Le Turnier
DOI: 10.12659/AJCR.945090
Am J Case Rep 2025; 26:e945090
1,080 2,146 0

20 Dec 2025 : Case report
Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment
Ugo Françoise
, Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle
, Paul Le Turnier
DOI: 10.12659/AJCR.945090
Am J Case Rep 2025; 26:e945090
1080 2146 0

19 Dec 2025 : Case report
Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis
Meghan Stevenson, Naveed Younis
DOI: 10.12659/AJCR.950208
Am J Case Rep 2025; 26:e950208
841 1,426 0

19 Dec 2025 : Case report
Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis
Meghan Stevenson, Naveed Younis
DOI: 10.12659/AJCR.950208
Am J Case Rep 2025; 26:e950208
841 1426 0

17 Dec 2025 : Case report
COVID-19-Associated MDA5-Mediated Necrotizing Myositis
Sarah Steadman, Amit Sikder, Harsh R. Desai
, Bradley Collins
, Tiffany Baker, Julie Worthington
DOI: 10.12659/AJCR.949788
Am J Case Rep 2025; 26:e949788
1,295 2,620 0

17 Dec 2025 : Case report
COVID-19-Associated MDA5-Mediated Necrotizing Myositis
Sarah Steadman, Amit Sikder, Harsh R. Desai
, Bradley Collins
, Tiffany Baker, Julie Worthington
DOI: 10.12659/AJCR.949788
Am J Case Rep 2025; 26:e949788
1295 2620 0

23 Dec 2025 : Case report
Platypnea-Orthodeoxia Syndrome Associated With a Right-to-Left Cardiac Shunt Detected by Lung Perfusion Scintigraphy
Yusuke Nakano
, Hirohiko Ando, Akinori Satake, Reiji Goto, Kentaro Mukai, Tetsuya Amano
DOI: 10.12659/AJCR.949642
Am J Case Rep 2025; 26:e949642
739 1,497 0

23 Dec 2025 : Case report
Platypnea-Orthodeoxia Syndrome Associated With a Right-to-Left Cardiac Shunt Detected by Lung Perfusion Scintigraphy
Yusuke Nakano
, Hirohiko Ando, Akinori Satake, Reiji Goto, Kentaro Mukai, Tetsuya Amano
DOI: 10.12659/AJCR.949642
Am J Case Rep 2025; 26:e949642
739 1497 0

22 Dec 2025 : Case report
Asymptomatic Lung Adenocarcinoma With Cardiac Metastasis at Initial Diagnosis: A Case Report
Tianyu Jin, Yongzhong Jiang, Yong Song
DOI: 10.12659/AJCR.951223
Am J Case Rep 2025; 26:e951223
793 2,078 0

22 Dec 2025 : Case report
Asymptomatic Lung Adenocarcinoma With Cardiac Metastasis at Initial Diagnosis: A Case Report
Tianyu Jin, Yongzhong Jiang, Yong Song
DOI: 10.12659/AJCR.951223
Am J Case Rep 2025; 26:e951223
793 2078 0

21 Dec 2025 : Case report
Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer
Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye
DOI: 10.12659/AJCR.947770
Am J Case Rep 2025; 26:e947770
968 1,948 0

21 Dec 2025 : Case report
Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer
Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye
DOI: 10.12659/AJCR.947770
Am J Case Rep 2025; 26:e947770
968 1948 0

20 Dec 2025 : Case report
Diagnostic Challenges of Abdominal Tumors Without Typical Imaging Features: From Misdiagnosis of Pancreatic Cystadenoma to Adrenal Pheochromocytoma and the Intraoperative Response
Haoyang Huang
, Dingwei Xu
, Zhangbin Chen, Jie Huang
DOI: 10.12659/AJCR.950574
Am J Case Rep 2025; 26:e950574
796 1,060 0

20 Dec 2025 : Case report
Diagnostic Challenges of Abdominal Tumors Without Typical Imaging Features: From Misdiagnosis of Pancreatic Cystadenoma to Adrenal Pheochromocytoma and the Intraoperative Response
Haoyang Huang
, Dingwei Xu
, Zhangbin Chen, Jie Huang
DOI: 10.12659/AJCR.950574
Am J Case Rep 2025; 26:e950574
796 1060 0

16 Dec 2025 : Case report
Subdural Empyema and Pneumocephalus From Chronic Polypoid Sinusitis in an Elderly Woman With Rapid Neurological Recovery: A Report of a Rare Case
John Martinez, Elizabeth Nagidi, Mark Rigby
, Lina Ataya, Aftab Macksood, Ghiath Bayasi, Kelsee Rotondo
DOI: 10.12659/AJCR.949999
Am J Case Rep 2025; 26:e949999
762 1,521 0

16 Dec 2025 : Case report
Subdural Empyema and Pneumocephalus From Chronic Polypoid Sinusitis in an Elderly Woman With Rapid Neurological Recovery: A Report of a Rare Case
John Martinez, Elizabeth Nagidi, Mark Rigby
, Lina Ataya, Aftab Macksood, Ghiath Bayasi, Kelsee Rotondo
DOI: 10.12659/AJCR.949999
Am J Case Rep 2025; 26:e949999
762 1521 0
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Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.952909
Case report
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Am J Case Rep In Press; DOI: 10.12659/AJCR.952577
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