Challenging differential diagnosis

09 Dec 2025 : Case report
A Rare Case of Emphysematous Pyelonephritis Following Retrograde Intrarenal Surgery in an Elderly Man
Weiyong Zhong
, Feihong Xu
, Shujiang Ye, Yu Liu, Wei Zhao, Zhenquan Lu, Lin Xiong, Xiang Xu
DOI: 10.12659/AJCR.949018
Am J Case Rep 2025; 26:e949018
650 1,021 0

09 Dec 2025 : Case report
A Rare Case of Emphysematous Pyelonephritis Following Retrograde Intrarenal Surgery in an Elderly Man
Weiyong Zhong
, Feihong Xu
, Shujiang Ye, Yu Liu, Wei Zhao, Zhenquan Lu, Lin Xiong, Xiang Xu
DOI: 10.12659/AJCR.949018
Am J Case Rep 2025; 26:e949018
650 1021 0

29 Nov 2025 : Case report
Mixed Cryoglobulinemia in the Setting of Monoclonal B-Cell Lymphocytosis and Monoclonal Gammopathy of Unknown Significance: A Case Report
Eleni Bouziani
, Luisa Ladel, Aaron James Stonestrom
DOI: 10.12659/AJCR.949597
Am J Case Rep 2025; 26:e949597
716 1,546 0

29 Nov 2025 : Case report
Mixed Cryoglobulinemia in the Setting of Monoclonal B-Cell Lymphocytosis and Monoclonal Gammopathy of Unknown Significance: A Case Report
Eleni Bouziani
, Luisa Ladel, Aaron James Stonestrom
DOI: 10.12659/AJCR.949597
Am J Case Rep 2025; 26:e949597
716 1546 0

07 Dec 2025 : Case report
Acute Kidney Injury from Mononuclear Cell-Predominated Interstitial Nephritis After Introduction of a Glucagon-Like Peptide-1 Receptor Agonist: A Case Report
Raweekarn Itsathitpaisarn, Nattavong Suksawad, Watsapol Wongwikrom, Jerasit Surintrspanont
, Thana Thongsricome
DOI: 10.12659/AJCR.949913
Am J Case Rep 2025; 26:e949913
920 1,916 0

07 Dec 2025 : Case report
Acute Kidney Injury from Mononuclear Cell-Predominated Interstitial Nephritis After Introduction of a Glucagon-Like Peptide-1 Receptor Agonist: A Case Report
Raweekarn Itsathitpaisarn, Nattavong Suksawad, Watsapol Wongwikrom, Jerasit Surintrspanont
, Thana Thongsricome
DOI: 10.12659/AJCR.949913
Am J Case Rep 2025; 26:e949913
920 1916 0

09 Dec 2025 : Case report
Behçet Disease and Cognitive Impairment: A Case Study of an Overlooked Symptom
Caroline Evanthe Nathania
, Astuti Prodjohardjono
, Noor Alia Susianti
, Abdul Gofir
, Cempaka Thursina Srie Setyaningrum
, Kamala Kan Nur Azza
, Ahmad Asmedi
, Sri Sutarni
DOI: 10.12659/AJCR.949699
Am J Case Rep 2025; 26:e949699
882 1,930 0

09 Dec 2025 : Case report
Behçet Disease and Cognitive Impairment: A Case Study of an Overlooked Symptom
Caroline Evanthe Nathania
, Astuti Prodjohardjono
, Noor Alia Susianti
, Abdul Gofir
, Cempaka Thursina Srie Setyaningrum
, Kamala Kan Nur Azza
, Ahmad Asmedi
, Sri Sutarni
DOI: 10.12659/AJCR.949699
Am J Case Rep 2025; 26:e949699
882 1930 0

30 Nov 2025 : Case report
Improvement of Renal Function in Atrial Fibrillation Patients via Catheter Ablation and Left Atrial Appendage Closure: A Case Report
Jiaying Chen, Caiyun Li, Yuegang Wang, Hongzeng Xu
DOI: 10.12659/AJCR.949421
Am J Case Rep 2025; 26:e949421
927 1,762 0

30 Nov 2025 : Case report
Improvement of Renal Function in Atrial Fibrillation Patients via Catheter Ablation and Left Atrial Appendage Closure: A Case Report
Jiaying Chen, Caiyun Li, Yuegang Wang, Hongzeng Xu
DOI: 10.12659/AJCR.949421
Am J Case Rep 2025; 26:e949421
927 1762 0

06 Dec 2025 : Case report
Severe Hemoperitoneum From a Ruptured Ovarian Cyst in a Patient with Antiphospholipid Syndrome and Antithrombin III Deficiency: A Case Report
Adrian A. Naoun
, Max Ramírez Vázquez, Yandy García Martin, Raysa D. López Torres, Ernesto Garcia Santiago
DOI: 10.12659/AJCR.949379
Am J Case Rep 2025; 26:e949379
1,130 2,770 0

06 Dec 2025 : Case report
Severe Hemoperitoneum From a Ruptured Ovarian Cyst in a Patient with Antiphospholipid Syndrome and Antithrombin III Deficiency: A Case Report
Adrian A. Naoun
, Max Ramírez Vázquez, Yandy García Martin, Raysa D. López Torres, Ernesto Garcia Santiago
DOI: 10.12659/AJCR.949379
Am J Case Rep 2025; 26:e949379
1130 2770 0

03 Nov 2025 : Case report
Novel PGM1 Mutation in Congenital Disorder of Glycosylation Type 1T: A Case Report of Liver Failure and Myopathy
Abdulaziz A. Al-Ahmari
DOI: 10.12659/AJCR.948797
Am J Case Rep 2025; 26:e948797
593 1,196 0

03 Nov 2025 : Case report
Novel PGM1 Mutation in Congenital Disorder of Glycosylation Type 1T: A Case Report of Liver Failure and Myopathy
Abdulaziz A. Al-Ahmari
DOI: 10.12659/AJCR.948797
Am J Case Rep 2025; 26:e948797
593 1196 0

28 Nov 2025 : Case report
Unexpected Schistosomiasis Diagnosed After Appendectomy in a Migrant Child
Isshak Mrabet-Deraoui
, Lorenzo Monforte
, Slobodan Prica
, Yvonne Schmiedel
DOI: 10.12659/AJCR.950906
Am J Case Rep 2025; 26:e950906
634 1,011 0

28 Nov 2025 : Case report
Unexpected Schistosomiasis Diagnosed After Appendectomy in a Migrant Child
Isshak Mrabet-Deraoui
, Lorenzo Monforte
, Slobodan Prica
, Yvonne Schmiedel
DOI: 10.12659/AJCR.950906
Am J Case Rep 2025; 26:e950906
634 1011 0

31 Oct 2025 : Case report
Apical Hypertrophic Cardiomyopathy: Diagnostic Challenges in a Patient with Hypertension and Obstructive Sleep Apnea
Jordan Llerena-Velastegui
, Daniela Benitez-Gutierrez, Diego Benitez-Zapata, Camila Escobar-Andrade, Daniela Corral-Hidalgo
DOI: 10.12659/AJCR.950268
Am J Case Rep 2025; 26:e950268
719 1,935 0

31 Oct 2025 : Case report
Apical Hypertrophic Cardiomyopathy: Diagnostic Challenges in a Patient with Hypertension and Obstructive Sleep Apnea
Jordan Llerena-Velastegui
, Daniela Benitez-Gutierrez, Diego Benitez-Zapata, Camila Escobar-Andrade, Daniela Corral-Hidalgo
DOI: 10.12659/AJCR.950268
Am J Case Rep 2025; 26:e950268
719 1935 0

06 Dec 2025 : Case report
Acute Kidney Injury After Accelerated Dosing of Tirzepatide in a Patient with Multiple Comorbidities: A Case Report
DOI: 10.12659/AJCR.950781
Am J Case Rep 2025; 26:e950781
1,197 9,188 0

06 Dec 2025 : Case report
Acute Kidney Injury After Accelerated Dosing of Tirzepatide in a Patient with Multiple Comorbidities: A Case Report
DOI: 10.12659/AJCR.950781
Am J Case Rep 2025; 26:e950781
1197 9188 0

02 Dec 2025 : Case report
Neuropsychiatric Symptoms After HHV-6 Encephalitis in an Immunocompetent Child: A Case Report
Dima Habanjar, Samah Trad, Daniel Charouf, Siham Kreidly, Rose-Mary Boustany
DOI: 10.12659/AJCR.950405
Am J Case Rep 2025; 26:e950405
816 2,194 0

02 Dec 2025 : Case report
Neuropsychiatric Symptoms After HHV-6 Encephalitis in an Immunocompetent Child: A Case Report
Dima Habanjar, Samah Trad, Daniel Charouf, Siham Kreidly, Rose-Mary Boustany
DOI: 10.12659/AJCR.950405
Am J Case Rep 2025; 26:e950405
816 2194 0

27 Nov 2025 : Case report
Combining Minimally Invasive Mitral Valve Replacement with Kidney Transplantation: A Pioneering Case
Abudar Al Ganadi, Ismail Al-Shameri, Nabeel Mughallis, Naseem Al-Wsabi
DOI: 10.12659/AJCR.948800
Am J Case Rep 2025; 26:e948800
1,328 1,213 0

27 Nov 2025 : Case report
Combining Minimally Invasive Mitral Valve Replacement with Kidney Transplantation: A Pioneering Case
Abudar Al Ganadi, Ismail Al-Shameri, Nabeel Mughallis, Naseem Al-Wsabi
DOI: 10.12659/AJCR.948800
Am J Case Rep 2025; 26:e948800
1328 1213 0

01 Nov 2025 : Case report
Post-COVID-19-Associated Asymptomatic Sarcoidosis with Hypercalcemia and Renal Dysfunction: A Case Report and Literature Review
Mrudula Thiriveedi
, Hersh Patel, Caitlin Curran, Siddharth Patel
, Sujatha Baddam
, Rafik ElBeblawy, Punuru J. Reddy
DOI: 10.12659/AJCR.950045
Am J Case Rep 2025; 26:e950045
821 2,246 0

01 Nov 2025 : Case report
Post-COVID-19-Associated Asymptomatic Sarcoidosis with Hypercalcemia and Renal Dysfunction: A Case Report and Literature Review
Mrudula Thiriveedi
, Hersh Patel, Caitlin Curran, Siddharth Patel
, Sujatha Baddam
, Rafik ElBeblawy, Punuru J. Reddy
DOI: 10.12659/AJCR.950045
Am J Case Rep 2025; 26:e950045
821 2246 0

05 Dec 2025 : Case report
Surgical Decompression in a 32-Year-Old Man with Chronic Onset of Thoracic Spontaneous Spinal Epidural Hematoma: A Case Report
Xi Xiang, Jie Wang, Han Wang, Qi Yang, Xun Sun, Shiyu Li, Lili Zou
DOI: 10.12659/AJCR.949805
Am J Case Rep 2025; 26:e949805
673 1,237 0

05 Dec 2025 : Case report
Surgical Decompression in a 32-Year-Old Man with Chronic Onset of Thoracic Spontaneous Spinal Epidural Hematoma: A Case Report
Xi Xiang, Jie Wang, Han Wang, Qi Yang, Xun Sun, Shiyu Li, Lili Zou
DOI: 10.12659/AJCR.949805
Am J Case Rep 2025; 26:e949805
673 1237 0

18 Nov 2025 : Case report
Exploring Maralixibat for Treatment-Resistant Pruritus in Intrahepatic Cholestasis of Pregnancy and Primary Biliary Cholangitis: A Case Report
Lara Alexandra Bersuch
, Andrea De Gottardi
DOI: 10.12659/AJCR.949019
Am J Case Rep 2025; 26:e949019
916 2,113 0

18 Nov 2025 : Case report
Exploring Maralixibat for Treatment-Resistant Pruritus in Intrahepatic Cholestasis of Pregnancy and Primary Biliary Cholangitis: A Case Report
Lara Alexandra Bersuch
, Andrea De Gottardi
DOI: 10.12659/AJCR.949019
Am J Case Rep 2025; 26:e949019
916 2113 0

17 Nov 2025 : Case report
Sclerosing Cholangitis and Multiple Liver Abscesses in a Patient with Thymoma, Myasthenia Gravis, and Immune Deficiency (Good’s Syndrome)
Shaul Yaari, Joshua Stokar
, Yehonatan Bar Moshe, Nurith Hiller, Elena Zuckerman, Samuel N. Heyman
DOI: 10.12659/AJCR.948856
Am J Case Rep 2025; 26:e948856
606 932 0

17 Nov 2025 : Case report
Sclerosing Cholangitis and Multiple Liver Abscesses in a Patient with Thymoma, Myasthenia Gravis, and Immune Deficiency (Good’s Syndrome)
Shaul Yaari, Joshua Stokar
, Yehonatan Bar Moshe, Nurith Hiller, Elena Zuckerman, Samuel N. Heyman
DOI: 10.12659/AJCR.948856
Am J Case Rep 2025; 26:e948856
606 932 0

28 Nov 2025 : Case report
Persistent Primitive Hypoglossal Artery in a 55-Year-Old Woman with Recurrent Dizziness, Identified on Ultrasound and Computed Tomography Imaging
Weiwei Zhang, Zhenli Huang, Liya Wei, Yanrong Sun, Fei Sang
DOI: 10.12659/AJCR.950244
Am J Case Rep 2025; 26:e950244
518 819 0

28 Nov 2025 : Case report
Persistent Primitive Hypoglossal Artery in a 55-Year-Old Woman with Recurrent Dizziness, Identified on Ultrasound and Computed Tomography Imaging
Weiwei Zhang, Zhenli Huang, Liya Wei, Yanrong Sun, Fei Sang
DOI: 10.12659/AJCR.950244
Am J Case Rep 2025; 26:e950244
518 819 0

22 Oct 2025 : Case report
Rheumatoid Arthritis-Associated Shoulder Rice Body Bursitis: Arthroscopic Management and Mechanistic Implications
Bo Xie, Changsheng Liao, Zhangshun Zhou, Minxiao Wang
DOI: 10.12659/AJCR.949580
Am J Case Rep 2025; 26:e949580
526 1,925 0

22 Oct 2025 : Case report
Rheumatoid Arthritis-Associated Shoulder Rice Body Bursitis: Arthroscopic Management and Mechanistic Implications
Bo Xie, Changsheng Liao, Zhangshun Zhou, Minxiao Wang
DOI: 10.12659/AJCR.949580
Am J Case Rep 2025; 26:e949580
526 1925 0

26 Nov 2025 : Case report
Pharmacological Intervention for Refractory Biofilm Infection After Hemipelvic Replacement Surgery: Multidisciplinary Management of a Case of Giant Cell Tumor of Bone
Liling Huang, Linyu Wang
, Hao Nong, Bin Liu, Yan Li
DOI: 10.12659/AJCR.949210
Am J Case Rep 2025; 26:e949210
748 1,197 0

26 Nov 2025 : Case report
Pharmacological Intervention for Refractory Biofilm Infection After Hemipelvic Replacement Surgery: Multidisciplinary Management of a Case of Giant Cell Tumor of Bone
Liling Huang, Linyu Wang
, Hao Nong, Bin Liu, Yan Li
DOI: 10.12659/AJCR.949210
Am J Case Rep 2025; 26:e949210
748 1197 0

18 Nov 2025 : Case report
Primary Cutaneous Cribriform Tumor with Clinical and Histological Diagnostic Challenges: Case Report and Literature Review of a Rare Skin Neoplasm
Wassim Hamadeh
, Elie Berbery
, Mohammad H. Abbas, Racil Allaw, Bassam F. Matar
DOI: 10.12659/AJCR.950487
Am J Case Rep 2025; 26:e950487
564 903 0

18 Nov 2025 : Case report
Primary Cutaneous Cribriform Tumor with Clinical and Histological Diagnostic Challenges: Case Report and Literature Review of a Rare Skin Neoplasm
Wassim Hamadeh
, Elie Berbery
, Mohammad H. Abbas, Racil Allaw, Bassam F. Matar
DOI: 10.12659/AJCR.950487
Am J Case Rep 2025; 26:e950487
564 903 0

17 Nov 2025 : Case report
Concurrent Mature and Immature Teratomas in Contralateral Ovaries in a 30-Year-Old Woman: A Case Report
Izabela Targosińska
, Dorota Lewkowicz
, Barbara Marzec-Kotarska
DOI: 10.12659/AJCR.949404
Am J Case Rep 2025; 26:e949404
527 2,180 0

17 Nov 2025 : Case report
Concurrent Mature and Immature Teratomas in Contralateral Ovaries in a 30-Year-Old Woman: A Case Report
Izabela Targosińska
, Dorota Lewkowicz
, Barbara Marzec-Kotarska
DOI: 10.12659/AJCR.949404
Am J Case Rep 2025; 26:e949404
527 2180 0

24 Nov 2025 : Case report
Bowel Obstruction Caused by Migration of an Intra-Gastric Balloon: A Rare Case Treated Laparoscopically
ٍSaeed Abdulrahman Alghamdi
, Yara Adel Alhomaidi, Nora Nasser Alqaoud, Alya Faisal Alsharif, Ali Mohammed Alzahrani, Rami Abdulrahman Sairafi
DOI: 10.12659/AJCR.948244
Am J Case Rep 2025; 26:e948244
477 1,060 0

24 Nov 2025 : Case report
Bowel Obstruction Caused by Migration of an Intra-Gastric Balloon: A Rare Case Treated Laparoscopically
ٍSaeed Abdulrahman Alghamdi
, Yara Adel Alhomaidi, Nora Nasser Alqaoud, Alya Faisal Alsharif, Ali Mohammed Alzahrani, Rami Abdulrahman Sairafi
DOI: 10.12659/AJCR.948244
Am J Case Rep 2025; 26:e948244
477 1060 0

24 Nov 2025 : Case report
Hypophysitis Induced by Tislelizumab: A Case Report of Somnolence and Delirium with Elevated Eosinophils
Fenglin Hu, Ni Lou, Guolin Wu
DOI: 10.12659/AJCR.948143
Am J Case Rep 2025; 26:e948143
829 1,085 0

24 Nov 2025 : Case report
Hypophysitis Induced by Tislelizumab: A Case Report of Somnolence and Delirium with Elevated Eosinophils
Fenglin Hu, Ni Lou, Guolin Wu
DOI: 10.12659/AJCR.948143
Am J Case Rep 2025; 26:e948143
829 1085 0

23 Nov 2025 : Case report
Idiopathic Intracranial Hypertension as the Initial Manifestation of Systemic Lupus Erythematosus: A Case Report and Literature Review
Abdulaziz Almalki, Asayel Abdullah Alosaimi, Abdulhameed Sarriyah
, Sarah Alqasem, Qusai Alwazna, Faisal Theeb Alqahtani
DOI: 10.12659/AJCR.950115
Am J Case Rep 2025; 26:e950115
905 2,141 0

23 Nov 2025 : Case report
Idiopathic Intracranial Hypertension as the Initial Manifestation of Systemic Lupus Erythematosus: A Case Report and Literature Review
Abdulaziz Almalki, Asayel Abdullah Alosaimi, Abdulhameed Sarriyah
, Sarah Alqasem, Qusai Alwazna, Faisal Theeb Alqahtani
DOI: 10.12659/AJCR.950115
Am J Case Rep 2025; 26:e950115
905 2141 0

19 Nov 2025 : Case report
Recombinant Factor VIIa Prophylaxis in 2 Brothers with Bernard-Soulier Syndrome
Eman Almatar, Sondus Alsharidah
, Omnia A. Hashem
DOI: 10.12659/AJCR.949654
Am J Case Rep 2025; 26:e949654
459 1,112 0

19 Nov 2025 : Case report
Recombinant Factor VIIa Prophylaxis in 2 Brothers with Bernard-Soulier Syndrome
Eman Almatar, Sondus Alsharidah
, Omnia A. Hashem
DOI: 10.12659/AJCR.949654
Am J Case Rep 2025; 26:e949654
459 1112 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.949976
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.950290
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Am J Case Rep In Press; DOI: 10.12659/AJCR.950607
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Am J Case Rep In Press; DOI: 10.12659/AJCR.950985
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