Challenging differential diagnosis

04 Jan 2026 : Case report
Effective Management of a Rare Case of Pediatric ANCA-Associated Vasculitis With Rituximab and Mycophenolate Mofetil
Yi Fang, Ali Kurady, Faris Q. Hashim, Blaine Berger, Arundhati Rao
DOI: 10.12659/AJCR.949274
Am J Case Rep 2026; 27:e949274
734 1,549 0

04 Jan 2026 : Case report
Effective Management of a Rare Case of Pediatric ANCA-Associated Vasculitis With Rituximab and Mycophenolate Mofetil
Yi Fang, Ali Kurady, Faris Q. Hashim, Blaine Berger, Arundhati Rao
DOI: 10.12659/AJCR.949274
Am J Case Rep 2026; 27:e949274
734 1549 0

08 Jan 2026 : Case report
Diagnostic Challenges in Atypical Hemolytic Uremic Syndrome: A Case of Artificial Mitral Valve Dysfunction as a Possible Trigger for Severe Thrombotic Microangiopathy
Gabriela Kot
, Agata Wróbel
, Błażej Kieszek
, Zbigniew Sablik
, Michał Nowicki
DOI: 10.12659/AJCR.948516
Am J Case Rep 2026; 27:e948516
622 749 0

08 Jan 2026 : Case report
Diagnostic Challenges in Atypical Hemolytic Uremic Syndrome: A Case of Artificial Mitral Valve Dysfunction as a Possible Trigger for Severe Thrombotic Microangiopathy
Gabriela Kot
, Agata Wróbel
, Błażej Kieszek
, Zbigniew Sablik
, Michał Nowicki
DOI: 10.12659/AJCR.948516
Am J Case Rep 2026; 27:e948516
622 749 0

07 Jan 2026 : Case report
Fampridine in Hereditary Spastic Paraplegia Type 4 With SPAST Variant c.683-2A>C: A Case Report
DOI: 10.12659/AJCR.951160
Am J Case Rep 2026; 27:e951160
468 900 0

07 Jan 2026 : Case report
Fampridine in Hereditary Spastic Paraplegia Type 4 With SPAST Variant c.683-2A>C: A Case Report
DOI: 10.12659/AJCR.951160
Am J Case Rep 2026; 27:e951160
468 900 0

05 Jan 2026 : Case report
Healing Beyond the Operating Room: Bedside Strategies for Necrotizing Fasciitis
Gabriela Kot
, Łukasz Świątek
, Tomasz Banasiewicz
DOI: 10.12659/AJCR.949754
Am J Case Rep 2026; 27:e949754
477 1,271 0

05 Jan 2026 : Case report
Healing Beyond the Operating Room: Bedside Strategies for Necrotizing Fasciitis
Gabriela Kot
, Łukasz Świątek
, Tomasz Banasiewicz
DOI: 10.12659/AJCR.949754
Am J Case Rep 2026; 27:e949754
477 1271 0

06 Jan 2026 : Case report
Rehabilitation of Lower Limb Motor Dysfunction and Neurogenic Bladder After Low-Dose Chlorfenapyr Poisoning With Delayed Rhabdomyolysis: A Case Report
Beibei Hou, Mingru Huang
, Xinwei Tang, Shan Tian, Gang Liu, Junfa Wu, Yi Wu, Hongyu Xie
DOI: 10.12659/AJCR.949455
Am J Case Rep 2026; 27:e949455
665 821 0

06 Jan 2026 : Case report
Rehabilitation of Lower Limb Motor Dysfunction and Neurogenic Bladder After Low-Dose Chlorfenapyr Poisoning With Delayed Rhabdomyolysis: A Case Report
Beibei Hou, Mingru Huang
, Xinwei Tang, Shan Tian, Gang Liu, Junfa Wu, Yi Wu, Hongyu Xie
DOI: 10.12659/AJCR.949455
Am J Case Rep 2026; 27:e949455
665 821 0

30 Dec 2025 : Case report
Beyond CKD-Associated Pruritus: Paraneoplastic Itch Revealing CLL/SLL in ESRD: A Case Report
Julia Kacperczyk
, Monika Dąbek, Agnieszka Makówka
, Michał Nowicki
DOI: 10.12659/AJCR.949787
Am J Case Rep 2025; 26:e949787
646 996 0

30 Dec 2025 : Case report
Beyond CKD-Associated Pruritus: Paraneoplastic Itch Revealing CLL/SLL in ESRD: A Case Report
Julia Kacperczyk
, Monika Dąbek, Agnieszka Makówka
, Michał Nowicki
DOI: 10.12659/AJCR.949787
Am J Case Rep 2025; 26:e949787
646 996 0

05 Jan 2026 : Case report
A 67-Year-Old Man With Hypertension Presenting With Spontaneous Rupture of a Large Splenic Artery Aneurysm Associated With Thrombus
Rakia Siala, Mohamed Ali Mseddi
, Chaima Yakoubi
, Alia Zehani, Hajer Hassine, Meriem Hsairi
, Rami Guizani
, Hela Kchir
, Karim Sassi, Mohamed Ben Slima
DOI: 10.12659/AJCR.950099
Am J Case Rep 2026; 27:e950099
578 973 0

05 Jan 2026 : Case report
A 67-Year-Old Man With Hypertension Presenting With Spontaneous Rupture of a Large Splenic Artery Aneurysm Associated With Thrombus
Rakia Siala, Mohamed Ali Mseddi
, Chaima Yakoubi
, Alia Zehani, Hajer Hassine, Meriem Hsairi
, Rami Guizani
, Hela Kchir
, Karim Sassi, Mohamed Ben Slima
DOI: 10.12659/AJCR.950099
Am J Case Rep 2026; 27:e950099
578 973 0

01 Jan 2026 : Case report
Twisted Mystery: Identifying Gallbladder Volvulus: Challenges in Preoperative Diagnosis
Yahya Al-Habbal, Ayman M. Al-Qaaneh
, Adnan A. Al Aloul, Sami Lazkani, Afnan Alghnaimat
DOI: 10.12659/AJCR.949283
Am J Case Rep 2026; 27:e949283
786 164 0

01 Jan 2026 : Case report
Twisted Mystery: Identifying Gallbladder Volvulus: Challenges in Preoperative Diagnosis
Yahya Al-Habbal, Ayman M. Al-Qaaneh
, Adnan A. Al Aloul, Sami Lazkani, Afnan Alghnaimat
DOI: 10.12659/AJCR.949283
Am J Case Rep 2026; 27:e949283
786 164 0

04 Jan 2026 : Case report
Peritoneal Post-Radiation Angiosarcoma in a Patient With a History of Radiation for Cervical Cancer
Xuan-Fang Qian, Xia-Wan Wang, He-Qing Yi, Lin-Fa Li
DOI: 10.12659/AJCR.949701
Am J Case Rep 2026; 27:e949701
552 721 0

04 Jan 2026 : Case report
Peritoneal Post-Radiation Angiosarcoma in a Patient With a History of Radiation for Cervical Cancer
Xuan-Fang Qian, Xia-Wan Wang, He-Qing Yi, Lin-Fa Li
DOI: 10.12659/AJCR.949701
Am J Case Rep 2026; 27:e949701
552 721 0

02 Jan 2026 : Case report
Multidisciplinary Management and Anesthesia Considerations for Diabetic Ketoacidosis With Hypertriglyceridemic Acute Pancreatitis in Pregnancy: A Case Report
Peiting Liu, Tao Li, Suquan Yu, Fan Liu, Lanji Huang
DOI: 10.12659/AJCR.949837
Am J Case Rep 2026; 27:e949837
827 98 0

02 Jan 2026 : Case report
Multidisciplinary Management and Anesthesia Considerations for Diabetic Ketoacidosis With Hypertriglyceridemic Acute Pancreatitis in Pregnancy: A Case Report
Peiting Liu, Tao Li, Suquan Yu, Fan Liu, Lanji Huang
DOI: 10.12659/AJCR.949837
Am J Case Rep 2026; 27:e949837
827 98 0

27 Nov 2025 : Case report
Gastric Bipartition with Functional Duodenum Exclusion (GBp-FDE) as a Possible Surgical Conversion of Sleeve Gastrectomy in Patients with De Novo GERD and Obesity Recidivism: Preliminary Results of a Case Series
Victor Ramos Mussa Dib
, Carlos Augusto Scussel Madalosso
, Paulo Reis Rizzo Esselin De Melo
, Almino Cardoso Ramos
, Luiz Alfredo Vieira D'Almeida
, Luciano Antozzi
, José María Balibrea del Castillo
, Patrick Noel
, Manoel Passos Galvão Neto
, Sonja Chiappetta
, Fernando de Barros
, André Teixeira
, Elinton Adami Chaim
, Ricardo Zorron
, Eudes Paiva de Godoy
, Caio Gustavo Gaspar de Aquino
, Giorgio Alfredo Pedroso Baretta
, Diogo Swain Kfouri
, Hiroji Okano Júnior
, Nilton Tokio Kawahara
, Augusto Cláudio de Almeida Tinoco
, Nicholas Tavares Kruel
, Joe Joaquim Waltrick Junior, Carlos Frota Dillenburg
, Félix Antônio Insaurriaga Dos Santos
, Rafael Antoniazzi Abaid
, Carlos Eduardo Alves Da Costa
, Gabriela Trentin Scortegagna
, Geovana F. Silva
, Halit Eren Taskin
, Ricardo M. Nassar
, Laurent Abram Layani
, Daniel Oscar Caiña
, Manuel Aceves Avalos
, Jorge Bravo Lópes
, José Sergio Verboonen Sotelo
, Ramon Vilallonga Puy
, Christine Karolina Stier
, Carlos Eduardo Domene
, Paula Volpe
, Amador García Ruiz de Gordejuela
, Luis Poggi
, Antônio Torres
, Miguel Ángel Carbajo
, Italo Braghetto
, Rui Ribeiro
, Chetan Parmar
DOI: 10.12659/AJCR.950798
Am J Case Rep 2025; 26:e950798
918 1,510 0

27 Nov 2025 : Case report
Gastric Bipartition with Functional Duodenum Exclusion (GBp-FDE) as a Possible Surgical Conversion of Sleeve Gastrectomy in Patients with De Novo GERD and Obesity Recidivism: Preliminary Results of a Case Series
Victor Ramos Mussa Dib
, Carlos Augusto Scussel Madalosso
, Paulo Reis Rizzo Esselin De Melo
, Almino Cardoso Ramos
, Luiz Alfredo Vieira D'Almeida
, Luciano Antozzi
, José María Balibrea del Castillo
, Patrick Noel
, Manoel Passos Galvão Neto
, Sonja Chiappetta
, Fernando de Barros
, André Teixeira
, Elinton Adami Chaim
, Ricardo Zorron
, Eudes Paiva de Godoy
, Caio Gustavo Gaspar de Aquino
, Giorgio Alfredo Pedroso Baretta
, Diogo Swain Kfouri
, Hiroji Okano Júnior
, Nilton Tokio Kawahara
, Augusto Cláudio de Almeida Tinoco
, Nicholas Tavares Kruel
, Joe Joaquim Waltrick Junior, Carlos Frota Dillenburg
, Félix Antônio Insaurriaga Dos Santos
, Rafael Antoniazzi Abaid
, Carlos Eduardo Alves Da Costa
, Gabriela Trentin Scortegagna
, Geovana F. Silva
, Halit Eren Taskin
, Ricardo M. Nassar
, Laurent Abram Layani
, Daniel Oscar Caiña
, Manuel Aceves Avalos
, Jorge Bravo Lópes
, José Sergio Verboonen Sotelo
, Ramon Vilallonga Puy
, Christine Karolina Stier
, Carlos Eduardo Domene
, Paula Volpe
, Amador García Ruiz de Gordejuela
, Luis Poggi
, Antônio Torres
, Miguel Ángel Carbajo
, Italo Braghetto
, Rui Ribeiro
, Chetan Parmar
DOI: 10.12659/AJCR.950798
Am J Case Rep 2025; 26:e950798
918 1510 0

29 Dec 2025 : Case report
Rapidly Progressive Disseminated Bacillus Calmette-Guérin Infection (BCGitis) in a 3-Month-Old Infant Without Immunodeficiency: A Case Report
Nathalya Queiroz Perillo, Taynara Heliodoro
, Leandro Azevedo De Camargo, Melissa Ameloti Gomes Avelino, Fayez Bahmad Jr.
DOI: 10.12659/AJCR.949742
Am J Case Rep 2025; 26:e949742
520 1,227 0

29 Dec 2025 : Case report
Rapidly Progressive Disseminated Bacillus Calmette-Guérin Infection (BCGitis) in a 3-Month-Old Infant Without Immunodeficiency: A Case Report
Nathalya Queiroz Perillo, Taynara Heliodoro
, Leandro Azevedo De Camargo, Melissa Ameloti Gomes Avelino, Fayez Bahmad Jr.
DOI: 10.12659/AJCR.949742
Am J Case Rep 2025; 26:e949742
520 1227 0

23 Dec 2025 : Case report
Low-Grade Appendiceal Mucinous Neoplasm as an Incidental Finding During Cesarean Section: A Case Report
Vesna Paunovic
, Tomislav Paunovic, Aleksa Jokic
, Bojana S. Ivic
, Aleksandra Petrovic, Nina Pejic
, Milos Stulic
, Jelena Martinov Nestorov, Jovan Jevtic
, Zeljko Vlaisavljevic
DOI: 10.12659/AJCR.949554
Am J Case Rep 2025; 26:e949554
683 1,444 0

23 Dec 2025 : Case report
Low-Grade Appendiceal Mucinous Neoplasm as an Incidental Finding During Cesarean Section: A Case Report
Vesna Paunovic
, Tomislav Paunovic, Aleksa Jokic
, Bojana S. Ivic
, Aleksandra Petrovic, Nina Pejic
, Milos Stulic
, Jelena Martinov Nestorov, Jovan Jevtic
, Zeljko Vlaisavljevic
DOI: 10.12659/AJCR.949554
Am J Case Rep 2025; 26:e949554
683 1444 0

26 Dec 2025 : Case report
Primary Well-Differentiated Neuroendocrine Tumor of the Breast: A Case Report and Literature Review
Sanjna Sai Gudena, Nilesh Digvijay Kashikar, Matthew Charles Wakefield
DOI: 10.12659/AJCR.950684
Am J Case Rep 2025; 26:e950684
533 1,152 0

26 Dec 2025 : Case report
Primary Well-Differentiated Neuroendocrine Tumor of the Breast: A Case Report and Literature Review
Sanjna Sai Gudena, Nilesh Digvijay Kashikar, Matthew Charles Wakefield
DOI: 10.12659/AJCR.950684
Am J Case Rep 2025; 26:e950684
533 1152 0

27 Dec 2025 : Case report
In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Features of Corneal Pseudodendritic Lesions in Hereditary Tyrosinemia Type 1
Rocco Bruno
, Sarah Donatelli, Leonardo Mastropasqua
, Mario Nubile
DOI: 10.12659/AJCR.949591
Am J Case Rep 2025; 26:e949591
493 692 0

27 Dec 2025 : Case report
In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Features of Corneal Pseudodendritic Lesions in Hereditary Tyrosinemia Type 1
Rocco Bruno
, Sarah Donatelli, Leonardo Mastropasqua
, Mario Nubile
DOI: 10.12659/AJCR.949591
Am J Case Rep 2025; 26:e949591
493 692 0

24 Dec 2025 : Case report
Bronchial Arteriovenous Malformation Detection Prior to Catheter Ablation for Paroxysmal Atrial Flutter and Fibrillation: A Case Report
Alexandra Arvanitaki
, Marios Georgios Bantidos
, Theodora Zaglavara
, Lydia Kalogeropoulou
, Athanasios Samaras
, Athina Nasoufidou
, Efstratios Karagiannidis
, Georgios Stavropoulos
, Apostolos Tzikas
, Nikolaos Fragakis
DOI: 10.12659/AJCR.949879
Am J Case Rep 2025; 26:e949879
540 813 0

24 Dec 2025 : Case report
Bronchial Arteriovenous Malformation Detection Prior to Catheter Ablation for Paroxysmal Atrial Flutter and Fibrillation: A Case Report
Alexandra Arvanitaki
, Marios Georgios Bantidos
, Theodora Zaglavara
, Lydia Kalogeropoulou
, Athanasios Samaras
, Athina Nasoufidou
, Efstratios Karagiannidis
, Georgios Stavropoulos
, Apostolos Tzikas
, Nikolaos Fragakis
DOI: 10.12659/AJCR.949879
Am J Case Rep 2025; 26:e949879
540 813 0

25 Dec 2025 : Case report
The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia
Moath Fateh
, Tariq Albweitel, Ahmad Odeh, Sarah Ghaith
DOI: 10.12659/AJCR.950626
Am J Case Rep 2025; 26:e950626
625 1,988 0

25 Dec 2025 : Case report
The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia
Moath Fateh
, Tariq Albweitel, Ahmad Odeh, Sarah Ghaith
DOI: 10.12659/AJCR.950626
Am J Case Rep 2025; 26:e950626
625 1988 0

20 Dec 2025 : Case report
Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment
Ugo Françoise
, Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle
, Paul Le Turnier
DOI: 10.12659/AJCR.945090
Am J Case Rep 2025; 26:e945090
840 1,504 0

20 Dec 2025 : Case report
Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment
Ugo Françoise
, Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle
, Paul Le Turnier
DOI: 10.12659/AJCR.945090
Am J Case Rep 2025; 26:e945090
840 1504 0

19 Dec 2025 : Case report
Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis
Meghan Stevenson, Naveed Younis
DOI: 10.12659/AJCR.950208
Am J Case Rep 2025; 26:e950208
716 966 0

19 Dec 2025 : Case report
Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis
Meghan Stevenson, Naveed Younis
DOI: 10.12659/AJCR.950208
Am J Case Rep 2025; 26:e950208
716 966 0

17 Dec 2025 : Case report
COVID-19-Associated MDA5-Mediated Necrotizing Myositis
Sarah Steadman, Amit Sikder, Harsh R. Desai
, Bradley Collins
, Tiffany Baker, Julie Worthington
DOI: 10.12659/AJCR.949788
Am J Case Rep 2025; 26:e949788
950 1,553 0

17 Dec 2025 : Case report
COVID-19-Associated MDA5-Mediated Necrotizing Myositis
Sarah Steadman, Amit Sikder, Harsh R. Desai
, Bradley Collins
, Tiffany Baker, Julie Worthington
DOI: 10.12659/AJCR.949788
Am J Case Rep 2025; 26:e949788
950 1553 0

23 Dec 2025 : Case report
Platypnea-Orthodeoxia Syndrome Associated With a Right-to-Left Cardiac Shunt Detected by Lung Perfusion Scintigraphy
Yusuke Nakano
, Hirohiko Ando, Akinori Satake, Reiji Goto, Kentaro Mukai, Tetsuya Amano
DOI: 10.12659/AJCR.949642
Am J Case Rep 2025; 26:e949642
563 1,032 0

23 Dec 2025 : Case report
Platypnea-Orthodeoxia Syndrome Associated With a Right-to-Left Cardiac Shunt Detected by Lung Perfusion Scintigraphy
Yusuke Nakano
, Hirohiko Ando, Akinori Satake, Reiji Goto, Kentaro Mukai, Tetsuya Amano
DOI: 10.12659/AJCR.949642
Am J Case Rep 2025; 26:e949642
563 1032 0

22 Dec 2025 : Case report
Asymptomatic Lung Adenocarcinoma With Cardiac Metastasis at Initial Diagnosis: A Case Report
Tianyu Jin, Yongzhong Jiang, Yong Song
DOI: 10.12659/AJCR.951223
Am J Case Rep 2025; 26:e951223
618 1,363 0

22 Dec 2025 : Case report
Asymptomatic Lung Adenocarcinoma With Cardiac Metastasis at Initial Diagnosis: A Case Report
Tianyu Jin, Yongzhong Jiang, Yong Song
DOI: 10.12659/AJCR.951223
Am J Case Rep 2025; 26:e951223
618 1363 0

21 Dec 2025 : Case report
Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer
Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye
DOI: 10.12659/AJCR.947770
Am J Case Rep 2025; 26:e947770
788 1,320 0

21 Dec 2025 : Case report
Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer
Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye
DOI: 10.12659/AJCR.947770
Am J Case Rep 2025; 26:e947770
788 1320 0

20 Dec 2025 : Case report
Diagnostic Challenges of Abdominal Tumors Without Typical Imaging Features: From Misdiagnosis of Pancreatic Cystadenoma to Adrenal Pheochromocytoma and the Intraoperative Response
Haoyang Huang
, Dingwei Xu
, Zhangbin Chen, Jie Huang
DOI: 10.12659/AJCR.950574
Am J Case Rep 2025; 26:e950574
653 778 0

20 Dec 2025 : Case report
Diagnostic Challenges of Abdominal Tumors Without Typical Imaging Features: From Misdiagnosis of Pancreatic Cystadenoma to Adrenal Pheochromocytoma and the Intraoperative Response
Haoyang Huang
, Dingwei Xu
, Zhangbin Chen, Jie Huang
DOI: 10.12659/AJCR.950574
Am J Case Rep 2025; 26:e950574
653 778 0

16 Dec 2025 : Case report
Subdural Empyema and Pneumocephalus From Chronic Polypoid Sinusitis in an Elderly Woman With Rapid Neurological Recovery: A Report of a Rare Case
John Martinez, Elizabeth Nagidi, Mark Rigby
, Lina Ataya, Aftab Macksood, Ghiath Bayasi, Kelsee Rotondo
DOI: 10.12659/AJCR.949999
Am J Case Rep 2025; 26:e949999
556 987 0

16 Dec 2025 : Case report
Subdural Empyema and Pneumocephalus From Chronic Polypoid Sinusitis in an Elderly Woman With Rapid Neurological Recovery: A Report of a Rare Case
John Martinez, Elizabeth Nagidi, Mark Rigby
, Lina Ataya, Aftab Macksood, Ghiath Bayasi, Kelsee Rotondo
DOI: 10.12659/AJCR.949999
Am J Case Rep 2025; 26:e949999
556 987 0
In Press
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Am J Case Rep In Press; DOI: 10.12659/AJCR.949976
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Am J Case Rep In Press; DOI: 10.12659/AJCR.950290
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Am J Case Rep In Press; DOI: 10.12659/AJCR.950607
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Am J Case Rep In Press; DOI: 10.12659/AJCR.950985
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