Challenging differential diagnosis
25 Dec 2025 : Case report 
The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia
Moath Fateh 
, Tariq Albweitel, Ahmad Odeh, Sarah Ghaith
DOI: 10.12659/AJCR.950626
Am J Case Rep 2025; 26:e950626
679 2,264 0
25 Dec 2025 : Case report
The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia
Moath Fateh , Tariq Albweitel, Ahmad Odeh, Sarah Ghaith
DOI: 10.12659/AJCR.950626
Am J Case Rep 2025; 26:e950626
679 2264 0
20 Dec 2025 : Case report 
Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment
Ugo Françoise , Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle , Paul Le Turnier
DOI: 10.12659/AJCR.945090
Am J Case Rep 2025; 26:e945090
913 1,695 0
20 Dec 2025 : Case report
Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment
Ugo Françoise , Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle , Paul Le Turnier
DOI: 10.12659/AJCR.945090
Am J Case Rep 2025; 26:e945090
913 1695 0
19 Dec 2025 : Case report 
Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis
Meghan Stevenson, Naveed Younis
DOI: 10.12659/AJCR.950208
Am J Case Rep 2025; 26:e950208
751 1,081 0
19 Dec 2025 : Case report
Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis
Meghan Stevenson, Naveed Younis
DOI: 10.12659/AJCR.950208
Am J Case Rep 2025; 26:e950208
751 1081 0
17 Dec 2025 : Case report
COVID-19-Associated MDA5-Mediated Necrotizing Myositis
Sarah Steadman, Amit Sikder, Harsh R. Desai , Bradley Collins , Tiffany Baker, Julie Worthington
DOI: 10.12659/AJCR.949788
Am J Case Rep 2025; 26:e949788
1,076 1,988 0
17 Dec 2025 : Case report
COVID-19-Associated MDA5-Mediated Necrotizing Myositis
Sarah Steadman, Amit Sikder, Harsh R. Desai , Bradley Collins , Tiffany Baker, Julie Worthington
DOI: 10.12659/AJCR.949788
Am J Case Rep 2025; 26:e949788
1076 1988 0
23 Dec 2025 : Case report 
Platypnea-Orthodeoxia Syndrome Associated With a Right-to-Left Cardiac Shunt Detected by Lung Perfusion Scintigraphy
Yusuke Nakano , Hirohiko Ando, Akinori Satake, Reiji Goto, Kentaro Mukai, Tetsuya Amano
DOI: 10.12659/AJCR.949642
Am J Case Rep 2025; 26:e949642
612 1,172 0
23 Dec 2025 : Case report
Platypnea-Orthodeoxia Syndrome Associated With a Right-to-Left Cardiac Shunt Detected by Lung Perfusion Scintigraphy
Yusuke Nakano , Hirohiko Ando, Akinori Satake, Reiji Goto, Kentaro Mukai, Tetsuya Amano
DOI: 10.12659/AJCR.949642
Am J Case Rep 2025; 26:e949642
612 1172 0
22 Dec 2025 : Case report 
Asymptomatic Lung Adenocarcinoma With Cardiac Metastasis at Initial Diagnosis: A Case Report
Tianyu Jin, Yongzhong Jiang, Yong Song
DOI: 10.12659/AJCR.951223
Am J Case Rep 2025; 26:e951223
667 1,517 0
22 Dec 2025 : Case report
Asymptomatic Lung Adenocarcinoma With Cardiac Metastasis at Initial Diagnosis: A Case Report
Tianyu Jin, Yongzhong Jiang, Yong Song
DOI: 10.12659/AJCR.951223
Am J Case Rep 2025; 26:e951223
667 1517 0
21 Dec 2025 : Case report
Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer
Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye
DOI: 10.12659/AJCR.947770
Am J Case Rep 2025; 26:e947770
842 1,471 0
21 Dec 2025 : Case report
Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer
Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye
DOI: 10.12659/AJCR.947770
Am J Case Rep 2025; 26:e947770
842 1471 0
20 Dec 2025 : Case report
Diagnostic Challenges of Abdominal Tumors Without Typical Imaging Features: From Misdiagnosis of Pancreatic Cystadenoma to Adrenal Pheochromocytoma and the Intraoperative Response
Haoyang Huang , Dingwei Xu , Zhangbin Chen, Jie Huang
DOI: 10.12659/AJCR.950574
Am J Case Rep 2025; 26:e950574
698 873 0
20 Dec 2025 : Case report
Diagnostic Challenges of Abdominal Tumors Without Typical Imaging Features: From Misdiagnosis of Pancreatic Cystadenoma to Adrenal Pheochromocytoma and the Intraoperative Response
Haoyang Huang , Dingwei Xu , Zhangbin Chen, Jie Huang
DOI: 10.12659/AJCR.950574
Am J Case Rep 2025; 26:e950574
698 873 0
16 Dec 2025 : Case report
Subdural Empyema and Pneumocephalus From Chronic Polypoid Sinusitis in an Elderly Woman With Rapid Neurological Recovery: A Report of a Rare Case
John Martinez, Elizabeth Nagidi, Mark Rigby , Lina Ataya, Aftab Macksood, Ghiath Bayasi, Kelsee Rotondo
DOI: 10.12659/AJCR.949999
Am J Case Rep 2025; 26:e949999
606 1,147 0
16 Dec 2025 : Case report
Subdural Empyema and Pneumocephalus From Chronic Polypoid Sinusitis in an Elderly Woman With Rapid Neurological Recovery: A Report of a Rare Case
John Martinez, Elizabeth Nagidi, Mark Rigby , Lina Ataya, Aftab Macksood, Ghiath Bayasi, Kelsee Rotondo
DOI: 10.12659/AJCR.949999
Am J Case Rep 2025; 26:e949999
606 1147 0
19 Dec 2025 : Case report
Primary Orbital Lymphoma Manifesting as Increased Intraocular Pressure: A Case Report
Miaomiao Sun, Zhaohui Xiong, Yincong Xu, Zhongyou Zhou, Jiale Wu, Jiangzhou Han, Lina Zhao
DOI: 10.12659/AJCR.951048
Am J Case Rep 2025; 26:e951048
796 1,266 0
19 Dec 2025 : Case report
Primary Orbital Lymphoma Manifesting as Increased Intraocular Pressure: A Case Report
Miaomiao Sun, Zhaohui Xiong, Yincong Xu, Zhongyou Zhou, Jiale Wu, Jiangzhou Han, Lina Zhao
DOI: 10.12659/AJCR.951048
Am J Case Rep 2025; 26:e951048
796 1266 0
21 Nov 2025 : Case report 
Left-Sided Perforated Appendicitis in an Elderly Man with Intestinal Malrotation: A Case Report
Jose Samaniego-Burneo , Jordan Llerena-Velastegui , Alberto Gordillo-Calero, Brenda Santamaria-Penafiel, Natalia Lopez-Yepez
DOI: 10.12659/AJCR.949960
Am J Case Rep 2025; 26:e949960
652 1,066 0
21 Nov 2025 : Case report
Left-Sided Perforated Appendicitis in an Elderly Man with Intestinal Malrotation: A Case Report
Jose Samaniego-Burneo , Jordan Llerena-Velastegui , Alberto Gordillo-Calero, Brenda Santamaria-Penafiel, Natalia Lopez-Yepez
DOI: 10.12659/AJCR.949960
Am J Case Rep 2025; 26:e949960
652 1066 0
18 Dec 2025 : Case report
Drug-Induced Lupus Erythematosus After 14 Years of Carbamazepine Use in a Patient With Neuromyelitis Optica Spectrum Disorder: A Case Report
Naho Ayuzawa-Takeda, Keisuke Saito, Hidetoshi Yanagida, Tomoko Oeda
DOI: 10.12659/AJCR.949233
Am J Case Rep 2025; 26:e949233
925 2,906 0
18 Dec 2025 : Case report
Drug-Induced Lupus Erythematosus After 14 Years of Carbamazepine Use in a Patient With Neuromyelitis Optica Spectrum Disorder: A Case Report
Naho Ayuzawa-Takeda, Keisuke Saito, Hidetoshi Yanagida, Tomoko Oeda
DOI: 10.12659/AJCR.949233
Am J Case Rep 2025; 26:e949233
925 2906 0
17 Dec 2025 : Case report
Splenic Hamartoma Diagnosed and Treated by Laparoscopic Splenectomy Associated With a Minimal Suprapubic Approach
Hikaru Ohtani, Tomohide Hori, Shigeki Nakayama, Satoru Umegae, Takao Iwanaga, Ryutaro Nishikawa, Takahiro Shimoyama, Sakurako Suzuki, Shigehito Nakashima, Takayuki Yamamoto
DOI: 10.12659/AJCR.950597
Am J Case Rep 2025; 26:e950597
597 879 0
17 Dec 2025 : Case report
Splenic Hamartoma Diagnosed and Treated by Laparoscopic Splenectomy Associated With a Minimal Suprapubic Approach
Hikaru Ohtani, Tomohide Hori, Shigeki Nakayama, Satoru Umegae, Takao Iwanaga, Ryutaro Nishikawa, Takahiro Shimoyama, Sakurako Suzuki, Shigehito Nakashima, Takayuki Yamamoto
DOI: 10.12659/AJCR.950597
Am J Case Rep 2025; 26:e950597
597 879 0
15 Dec 2025 : Case report 
Compartment Syndrome Secondary to Phlegmasia Cerulea Dolens in a Patient With Crohn’s Disease
Saad Mohammed Alshahrani , Raghad Ibrahim Alkoblan, Reem Abdulaziz Alturki, Shahad Mohammed Alashgar
DOI: 10.12659/AJCR.948950
Am J Case Rep 2025; 26:e948950
609 880 0
15 Dec 2025 : Case report
Compartment Syndrome Secondary to Phlegmasia Cerulea Dolens in a Patient With Crohn’s Disease
Saad Mohammed Alshahrani , Raghad Ibrahim Alkoblan, Reem Abdulaziz Alturki, Shahad Mohammed Alashgar
DOI: 10.12659/AJCR.948950
Am J Case Rep 2025; 26:e948950
609 880 0
16 Dec 2025 : Case report
Electronic Gastroscopy in Identifying Hidden Tonsillar Foreign Bodies: A Case of a Completely Embedded Sunflower Seed Shell
Deng Liang
DOI: 10.12659/AJCR.949052
Am J Case Rep 2025; 26:e949052
583 837 0
16 Dec 2025 : Case report
Electronic Gastroscopy in Identifying Hidden Tonsillar Foreign Bodies: A Case of a Completely Embedded Sunflower Seed Shell
Deng Liang
DOI: 10.12659/AJCR.949052
Am J Case Rep 2025; 26:e949052
583 837 0
15 Dec 2025 : Case report
Primary Pulmonary Osteosarcoma Presenting as a 1.7-cm Subpleural Nodule in a 61-Year-Old Man: A Case Report
Xin Yang, Wen Guang Zhao, Chao Gao, Sheng Lin
DOI: 10.12659/AJCR.949034
Am J Case Rep 2025; 26:e949034
681 811 0
15 Dec 2025 : Case report
Primary Pulmonary Osteosarcoma Presenting as a 1.7-cm Subpleural Nodule in a 61-Year-Old Man: A Case Report
Xin Yang, Wen Guang Zhao, Chao Gao, Sheng Lin
DOI: 10.12659/AJCR.949034
Am J Case Rep 2025; 26:e949034
681 811 0
12 Dec 2025 : Case report 
Unpredictable Evolution of Pilocytic Astrocytoma in Adults: A Case Series and Diagnostic Challenges
Anamaria Sincu, Cristian-Ionut Orasanu , Raluca Ioana Voda , Madalina Bosoteanu , Manuela Enciu , Sorin Vamesu , Sinziana Andra Ghitoi, Mariana Deacu
DOI: 10.12659/AJCR.947774
Am J Case Rep 2025; 26:e947774
854 3,303 0
12 Dec 2025 : Case report
Unpredictable Evolution of Pilocytic Astrocytoma in Adults: A Case Series and Diagnostic Challenges
Anamaria Sincu, Cristian-Ionut Orasanu , Raluca Ioana Voda , Madalina Bosoteanu , Manuela Enciu , Sorin Vamesu , Sinziana Andra Ghitoi, Mariana Deacu
DOI: 10.12659/AJCR.947774
Am J Case Rep 2025; 26:e947774
854 3303 0
14 Dec 2025 : Case report
Bruton’s Agammaglobulinemia: Case Series and Literature Review From King Fahad Central Hospital, Jizan, Saudi Arabia
Ahmed Shamakhi, Nabil Dhayhi, Shatha Matabi, Manal Maashi, Abdullah Dhaifallah Hamdi, Bander Ali, Fadhel Hazazi, Abdullah H. Alhamoud
DOI: 10.12659/AJCR.949936
Am J Case Rep 2025; 26:e949936
879 2,256 0
14 Dec 2025 : Case report
Bruton’s Agammaglobulinemia: Case Series and Literature Review From King Fahad Central Hospital, Jizan, Saudi Arabia
Ahmed Shamakhi, Nabil Dhayhi, Shatha Matabi, Manal Maashi, Abdullah Dhaifallah Hamdi, Bander Ali, Fadhel Hazazi, Abdullah H. Alhamoud
DOI: 10.12659/AJCR.949936
Am J Case Rep 2025; 26:e949936
879 2256 0
11 Dec 2025 : Case report 
A 60-Year-Old Man with an Incidental Finding of an Asymptomatic Aneurysm of the Right Gastroepiploic Artery Managed by Laparoscopic Resection
Maksymilian Baryła , Paweł Kazimierz Ziemiański
DOI: 10.12659/AJCR.948020
Am J Case Rep 2025; 26:e948020
605 860 0
11 Dec 2025 : Case report
A 60-Year-Old Man with an Incidental Finding of an Asymptomatic Aneurysm of the Right Gastroepiploic Artery Managed by Laparoscopic Resection
Maksymilian Baryła , Paweł Kazimierz Ziemiański
DOI: 10.12659/AJCR.948020
Am J Case Rep 2025; 26:e948020
605 860 0
30 Nov 2025 : Case report
Afebrile HSV-2 Encephalitis with Radiographic Atypia and Minimal Systemic Inflammation: A Case Report
Shunsuke Kondo , Wejdan Abo Qayas, Osama Hasan, Rachel Haide N. Tacata, Matthew W. Kobylinski, Lorrance Majewski
DOI: 10.12659/AJCR.950444
Am J Case Rep 2025; 26:e950444
717 1,482 0
30 Nov 2025 : Case report
Afebrile HSV-2 Encephalitis with Radiographic Atypia and Minimal Systemic Inflammation: A Case Report
Shunsuke Kondo , Wejdan Abo Qayas, Osama Hasan, Rachel Haide N. Tacata, Matthew W. Kobylinski, Lorrance Majewski
DOI: 10.12659/AJCR.950444
Am J Case Rep 2025; 26:e950444
717 1482 0
07 Dec 2025 : Case report 
Campfire Smoke as a Plausible Trigger for Vasospastic Angina: Insights From a Case Report
Gabrielle Denault, Anne-Sophie Lê, Emad Tahir, Stéphane Perron
DOI: 10.12659/AJCR.949363
Am J Case Rep 2025; 26:e949363
773 2,386 0
07 Dec 2025 : Case report
Campfire Smoke as a Plausible Trigger for Vasospastic Angina: Insights From a Case Report
Gabrielle Denault, Anne-Sophie Lê, Emad Tahir, Stéphane Perron
DOI: 10.12659/AJCR.949363
Am J Case Rep 2025; 26:e949363
773 2386 0
10 Dec 2025 : Case report 
Isolated Transient Neonatal Ascites in a Preterm Infant Born to a Mother with Mirror Syndrome: A Case Report
Mo’ath Abu Hamdeh, Rasmea Mohammad Asad, Zeidan Abdalsalam, Mohammad Maraqah, Lema Saleh Khaled Jaber, Mai M.R. Rostom, Majed Methqal Abu Jaish
DOI: 10.12659/AJCR.949587
Am J Case Rep 2025; 26:e949587
783 1,608 0
10 Dec 2025 : Case report
Isolated Transient Neonatal Ascites in a Preterm Infant Born to a Mother with Mirror Syndrome: A Case Report
Mo’ath Abu Hamdeh, Rasmea Mohammad Asad, Zeidan Abdalsalam, Mohammad Maraqah, Lema Saleh Khaled Jaber, Mai M.R. Rostom, Majed Methqal Abu Jaish
DOI: 10.12659/AJCR.949587
Am J Case Rep 2025; 26:e949587
783 1608 0
03 Dec 2025 : Case report
Endoscopic Retrieval of Ingested Button Battery From a Colonic Diverticulum in an Alzheimer’s Patient: A Case Report
Kazuko Hizukuri, Yasuhiko Fujita, Teruyoshi Amagai
DOI: 10.12659/AJCR.949004
Am J Case Rep 2025; 26:e949004
531 815 0
03 Dec 2025 : Case report
Endoscopic Retrieval of Ingested Button Battery From a Colonic Diverticulum in an Alzheimer’s Patient: A Case Report
Kazuko Hizukuri, Yasuhiko Fujita, Teruyoshi Amagai
DOI: 10.12659/AJCR.949004
Am J Case Rep 2025; 26:e949004
531 815 0
04 Dec 2025 : Case report 
A 27-Year-Old Man with Chronic Traumatic Pancreatic Fistula Managed with Percutaneous Microwave Ablation
Raphael AlSarma, Abdel-Rahman Salameh, Talal Sultan M. Althobity, Farooq Bacha, Mohamed Karji Almarzooqi, Iyad Hassan
DOI: 10.12659/AJCR.949541
Am J Case Rep 2025; 26:e949541
583 973 0
04 Dec 2025 : Case report
A 27-Year-Old Man with Chronic Traumatic Pancreatic Fistula Managed with Percutaneous Microwave Ablation
Raphael AlSarma, Abdel-Rahman Salameh, Talal Sultan M. Althobity, Farooq Bacha, Mohamed Karji Almarzooqi, Iyad Hassan
DOI: 10.12659/AJCR.949541
Am J Case Rep 2025; 26:e949541
583 973 0
01 Dec 2025 : Case report
Late-Onset Mesh Infection 10 Years After Right Inguinal Hernia Repair: A Case Report
Ryoichi Shimizu , Masahito Uji, Hideo Matsubara, Yasutomo Miura, Yudai Aoki, Takahiro Maehata, Kazumasa Matsuoka, Yasuji Mokuno
DOI: 10.12659/AJCR.949941
Am J Case Rep 2025; 26:e949941
749 2,886 0
01 Dec 2025 : Case report
Late-Onset Mesh Infection 10 Years After Right Inguinal Hernia Repair: A Case Report
Ryoichi Shimizu , Masahito Uji, Hideo Matsubara, Yasutomo Miura, Yudai Aoki, Takahiro Maehata, Kazumasa Matsuoka, Yasuji Mokuno
DOI: 10.12659/AJCR.949941
Am J Case Rep 2025; 26:e949941
749 2886 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.949976
Case report 
Am J Case Rep In Press; DOI: 10.12659/AJCR.950290
Case report 
Am J Case Rep In Press; DOI: 10.12659/AJCR.950607
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.950985
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