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Challenging differential diagnosis

#947844

23 Mar 2026 : Case report  Indonesia

Isolated Premature Menarche in a 17-Month-Old: A Case Report

Dewi Rani Pelitawati ORCID logo, Artha Falentin Putri Susilo ORCID logo, Anita Rachmawati ORCID logo, Wiryawan Permadi ORCID logo, Putri Nadhira Adinda Adriansyah ORCID logo, Nabila Chantikarizky Hasanah ORCID logo

DOI: 10.12659/AJCR.947844

Am J Case Rep 2026; 27:e947844

849 2,778 0

#947844

23 Mar 2026 : Case report  Indonesia

Isolated Premature Menarche in a 17-Month-Old: A Case Report

Dewi Rani Pelitawati ORCID logo, Artha Falentin Putri Susilo ORCID logo, Anita Rachmawati ORCID logo, Wiryawan Permadi ORCID logo, Putri Nadhira Adinda Adriansyah ORCID logo, Nabila Chantikarizky Hasanah ORCID logo

DOI: 10.12659/AJCR.947844

Am J Case Rep 2026; 27:e947844

849 2778 0

#951658

23 Mar 2026 : Case report  USA

Diagnostic Value of Next-Generation Sequencing (NGS) and Microarray in Characterizing Tumor Origin: A Challenging and Educational Case

Xiaofeng Zhao ORCID logo

DOI: 10.12659/AJCR.951658

Am J Case Rep 2026; 27:e951658

612 965 0

#951658

23 Mar 2026 : Case report  USA

Diagnostic Value of Next-Generation Sequencing (NGS) and Microarray in Characterizing Tumor Origin: A Challenging and Educational Case

Xiaofeng Zhao ORCID logo

DOI: 10.12659/AJCR.951658

Am J Case Rep 2026; 27:e951658

612 965 0

#950925

21 Mar 2026 : Case report  USA

Robotic Surgical Repair of a Parahiatal Hernia: A Case Report

Sarah Hughes ORCID logo, Harmanpreet Kakkar ORCID logo

DOI: 10.12659/AJCR.950925

Am J Case Rep 2026; 27:e950925

549 915 0

#950925

21 Mar 2026 : Case report  USA

Robotic Surgical Repair of a Parahiatal Hernia: A Case Report

Sarah Hughes ORCID logo, Harmanpreet Kakkar ORCID logo

DOI: 10.12659/AJCR.950925

Am J Case Rep 2026; 27:e950925

549 915 0

#950305

20 Mar 2026 : Case report  Brazil

Nonatherosclerotic Subclavian Steal Syndrome Due to Brachiocephalic Trunk Kinking in an Elderly Woman: A Case Report

Mauro De Deus Passos, Pedro R.M. Negreiros de Almeida, Rodolfo Loureiro Borges de Souza, Arthur Barroso Vidal Vilarinho, Daniella de Sousa Mendes Moreira Alves, Luciano Moreira Alves

DOI: 10.12659/AJCR.950305

Am J Case Rep 2026; 27:e950305

688 1,714 0

#950305

20 Mar 2026 : Case report  Brazil

Nonatherosclerotic Subclavian Steal Syndrome Due to Brachiocephalic Trunk Kinking in an Elderly Woman: A Case Report

Mauro De Deus Passos, Pedro R.M. Negreiros de Almeida, Rodolfo Loureiro Borges de Souza, Arthur Barroso Vidal Vilarinho, Daniella de Sousa Mendes Moreira Alves, Luciano Moreira Alves

DOI: 10.12659/AJCR.950305

Am J Case Rep 2026; 27:e950305

688 1714 0

#951064

17 Feb 2026 : Case report  United Arab Emirates

Anti-MDA5 Antibody-Positive Dermatomyositis in Emirati Patients: A Case Series Highlighting Clinical Variability

Deena Ahmed, Khulood Khawaja, Afra Al Dhaheri, Abdulla Alshamsi, Amna Almheiri, Ahlam Almarzooqi, Sarah Al Qassimi, Rajaie Namas, Gehad ElGhazali

DOI: 10.12659/AJCR.951064

Am J Case Rep 2026; 27:e951064

1,215 3,120 0

#951064

17 Feb 2026 : Case report  United Arab Emirates

Anti-MDA5 Antibody-Positive Dermatomyositis in Emirati Patients: A Case Series Highlighting Clinical Variability

Deena Ahmed, Khulood Khawaja, Afra Al Dhaheri, Abdulla Alshamsi, Amna Almheiri, Ahlam Almarzooqi, Sarah Al Qassimi, Rajaie Namas, Gehad ElGhazali

DOI: 10.12659/AJCR.951064

Am J Case Rep 2026; 27:e951064

1215 3120 0

#951570

19 Mar 2026 : Case report  Thailand

Early Diagnosis of Nieman–Pick Disease Type C and Rapid Response of Gelastic Cataplexy to Treatment With N-Acetyl-L-Leucine: A Case Report

Kitiwan Rojnueangnit ORCID logo, Sukita Puttamanee ORCID logo, Sukkrawan Intarakhao, Khanittha Khusiwilai ORCID logo

DOI: 10.12659/AJCR.951570

Am J Case Rep 2026; 27:e951570

823 1,601 0

#951570

19 Mar 2026 : Case report  Thailand

Early Diagnosis of Nieman–Pick Disease Type C and Rapid Response of Gelastic Cataplexy to Treatment With N-Acetyl-L-Leucine: A Case Report

Kitiwan Rojnueangnit ORCID logo, Sukita Puttamanee ORCID logo, Sukkrawan Intarakhao, Khanittha Khusiwilai ORCID logo

DOI: 10.12659/AJCR.951570

Am J Case Rep 2026; 27:e951570

823 1601 0

#950688

17 Mar 2026 : Case report  Saudi Arabia

Linezolid-Associated Triad of Acute Pancreatitis, Lactic Acidosis, and Hypoglycemia: A Rare Case Report and Literature Review

Manar Abdullah Makin, Ahmed Hussein Subki ORCID logo, Manal Ismail Bokhary

DOI: 10.12659/AJCR.950688

Am J Case Rep 2026; 27:e950688

819 1,682 0

#950688

17 Mar 2026 : Case report  Saudi Arabia

Linezolid-Associated Triad of Acute Pancreatitis, Lactic Acidosis, and Hypoglycemia: A Rare Case Report and Literature Review

Manar Abdullah Makin, Ahmed Hussein Subki ORCID logo, Manal Ismail Bokhary

DOI: 10.12659/AJCR.950688

Am J Case Rep 2026; 27:e950688

819 1682 0

#951696

17 Mar 2026 : Case report  Indonesia

Congenital Limb Duplication and Spinal Dysraphism: A Rare Case Report Highlighting Single-Stage Multidisciplinary Surgery and Life-Changing Outcome

Iman Dwi Winanto ORCID logo, Jefryan Sofyan ORCID logo, Tommy Mandagi ORCID logo, Ricovially Davya Guci ORCID logo, Abdurrahman Mouza ORCID logo, Arya Tjipta Prananda ORCID logo

DOI: 10.12659/AJCR.951696

Am J Case Rep 2026; 27:e951696

802 2,105 0

#951696

17 Mar 2026 : Case report  Indonesia

Congenital Limb Duplication and Spinal Dysraphism: A Rare Case Report Highlighting Single-Stage Multidisciplinary Surgery and Life-Changing Outcome

Iman Dwi Winanto ORCID logo, Jefryan Sofyan ORCID logo, Tommy Mandagi ORCID logo, Ricovially Davya Guci ORCID logo, Abdurrahman Mouza ORCID logo, Arya Tjipta Prananda ORCID logo

DOI: 10.12659/AJCR.951696

Am J Case Rep 2026; 27:e951696

802 2105 0

#951056

16 Mar 2026 : Case report  Taiwan

A 53-Year-Old Male Smoker With Advanced Oral Squamous Cell Carcinoma Associated With Paraneoplastic Leukemoid Reaction

Chi-Yuan Yeh ORCID logo

DOI: 10.12659/AJCR.951056

Am J Case Rep 2026; 27:e951056

632 1,225 0

#951056

16 Mar 2026 : Case report  Taiwan

A 53-Year-Old Male Smoker With Advanced Oral Squamous Cell Carcinoma Associated With Paraneoplastic Leukemoid Reaction

Chi-Yuan Yeh ORCID logo

DOI: 10.12659/AJCR.951056

Am J Case Rep 2026; 27:e951056

632 1225 0

#951603

16 Mar 2026 : Case report  USA

Fatal Cardiomyopathy Secondary to Seronegative Immune-Mediated Necrotizing Myopathy: A Case Report

Benjamin D. Lueck, Alyssa K.W. Maclean, Georges El Hasbani, Andrew J. Layman, Floranne C. Ernste, Courtney A. Arment

DOI: 10.12659/AJCR.951603

Am J Case Rep 2026; 27:e951603

825 2,462 0

#951603

16 Mar 2026 : Case report  USA

Fatal Cardiomyopathy Secondary to Seronegative Immune-Mediated Necrotizing Myopathy: A Case Report

Benjamin D. Lueck, Alyssa K.W. Maclean, Georges El Hasbani, Andrew J. Layman, Floranne C. Ernste, Courtney A. Arment

DOI: 10.12659/AJCR.951603

Am J Case Rep 2026; 27:e951603

825 2462 0

#950774

15 Mar 2026 : Case report  Thailand

Delayed Recognition of Systemic Lupus Erythematosus Presenting With Visceral Muscle Dysmotility and Chronic Mucus-Bloody Enteropathy: A Case Report

Settanan Plangsiri ORCID logo, Manisara Jirapornsuwan, Pat Ngamdachakij, Dhanesh Pitidhammabhorn, Wannisa Wongpipathpong ORCID logo

DOI: 10.12659/AJCR.950774

Am J Case Rep 2026; 27:e950774

637 1,695 0

#950774

15 Mar 2026 : Case report  Thailand

Delayed Recognition of Systemic Lupus Erythematosus Presenting With Visceral Muscle Dysmotility and Chronic Mucus-Bloody Enteropathy: A Case Report

Settanan Plangsiri ORCID logo, Manisara Jirapornsuwan, Pat Ngamdachakij, Dhanesh Pitidhammabhorn, Wannisa Wongpipathpong ORCID logo

DOI: 10.12659/AJCR.950774

Am J Case Rep 2026; 27:e950774

637 1695 0

#951661

14 Mar 2026 : Case report  USA

A 43-Year-Old Man With Isolated Cutaneous Lymphomatoid Granulomatosis Presenting as a Chronic Necrotizing Ulcer of the Upper Arm

Adebola Oluwabusayo Adetiloye ORCID logo, Anim Asif ORCID logo, Olurotimi J. Badero ORCID logo, Tan Zimri, Nadine C. Brissett-Williams

DOI: 10.12659/AJCR.951661

Am J Case Rep 2026; 27:e951661

673 1,078 0

#951661

14 Mar 2026 : Case report  USA

A 43-Year-Old Man With Isolated Cutaneous Lymphomatoid Granulomatosis Presenting as a Chronic Necrotizing Ulcer of the Upper Arm

Adebola Oluwabusayo Adetiloye ORCID logo, Anim Asif ORCID logo, Olurotimi J. Badero ORCID logo, Tan Zimri, Nadine C. Brissett-Williams

DOI: 10.12659/AJCR.951661

Am J Case Rep 2026; 27:e951661

673 1078 0

#951331

12 Feb 2026 : Case report  USA

Bilateral Adrenal Infarction as an Uncommon Complication of Heparin-Induced Thrombocytopenia: A Case Report

Abhinav Singla ORCID logo, Asmita Addanki ORCID logo, Aleena Shahnawaz ORCID logo, Alyssa Catherine Raj ORCID logo, Anam Sadia, Shah Rukh, Muhammad Ali ORCID logo, Aleksandra Murawska Baptista ORCID logo

DOI: 10.12659/AJCR.951331

Am J Case Rep 2026; 27:e951331

885 1,545 0

#951331

12 Feb 2026 : Case report  USA

Bilateral Adrenal Infarction as an Uncommon Complication of Heparin-Induced Thrombocytopenia: A Case Report

Abhinav Singla ORCID logo, Asmita Addanki ORCID logo, Aleena Shahnawaz ORCID logo, Alyssa Catherine Raj ORCID logo, Anam Sadia, Shah Rukh, Muhammad Ali ORCID logo, Aleksandra Murawska Baptista ORCID logo

DOI: 10.12659/AJCR.951331

Am J Case Rep 2026; 27:e951331

885 1545 0

#949900

14 Mar 2026 : Case report  USA

A Case of Uncommon Tuberculosis Infection Involving the Sternoclavicular Joint

Shrimahitha Duraiyarasan, Ruijia Hou, Audrey A. Boadu, Phelese Smith, Crisanta Simon ORCID logo, Bethel Shiferaw

DOI: 10.12659/AJCR.949900

Am J Case Rep 2026; 27:e949900

609 1,672 0

#949900

14 Mar 2026 : Case report  USA

A Case of Uncommon Tuberculosis Infection Involving the Sternoclavicular Joint

Shrimahitha Duraiyarasan, Ruijia Hou, Audrey A. Boadu, Phelese Smith, Crisanta Simon ORCID logo, Bethel Shiferaw

DOI: 10.12659/AJCR.949900

Am J Case Rep 2026; 27:e949900

609 1672 0

#950876

13 Mar 2026 : Case report  USA

A Challenging Case of Pleomorphic Lipoma of the Shoulder Mimicking Liposarcoma

Yunan Han ORCID logo, Abid Qureshi, Haleigh M. Heubeck, Yingxian Liu, Luca Milone

DOI: 10.12659/AJCR.950876

Am J Case Rep 2026; 27:e950876

520 1,037 0

#950876

13 Mar 2026 : Case report  USA

A Challenging Case of Pleomorphic Lipoma of the Shoulder Mimicking Liposarcoma

Yunan Han ORCID logo, Abid Qureshi, Haleigh M. Heubeck, Yingxian Liu, Luca Milone

DOI: 10.12659/AJCR.950876

Am J Case Rep 2026; 27:e950876

520 1037 0

#951102

12 Mar 2026 : Case report  China

Anastomotic-Transverse Colon Fistula Following Gastrectomy: A Case Report of Delayed Diagnosis 14 Years After Surgery

Yalan Xu, Zhongshu Li, Wenjia Tian, Ning Chen

DOI: 10.12659/AJCR.951102

Am J Case Rep 2026; 27:e951102

599 1,201 0

#951102

12 Mar 2026 : Case report  China

Anastomotic-Transverse Colon Fistula Following Gastrectomy: A Case Report of Delayed Diagnosis 14 Years After Surgery

Yalan Xu, Zhongshu Li, Wenjia Tian, Ning Chen

DOI: 10.12659/AJCR.951102

Am J Case Rep 2026; 27:e951102

599 1201 0

#951908

12 Mar 2026 : Case report  USA

Systemic Lupus Erythematosus With IgA Nephropathy: Challenges in Diagnosis and Management

Mandar Shah ORCID logo, Farheen Malik ORCID logo, Mihika Shah ORCID logo, Maurya Devang Patel ORCID logo, Rutika Pathakjee ORCID logo, Sapan Pandya ORCID logo

DOI: 10.12659/AJCR.951908

Am J Case Rep 2026; 27:e951908

653 1,980 0

#951908

12 Mar 2026 : Case report  USA

Systemic Lupus Erythematosus With IgA Nephropathy: Challenges in Diagnosis and Management

Mandar Shah ORCID logo, Farheen Malik ORCID logo, Mihika Shah ORCID logo, Maurya Devang Patel ORCID logo, Rutika Pathakjee ORCID logo, Sapan Pandya ORCID logo

DOI: 10.12659/AJCR.951908

Am J Case Rep 2026; 27:e951908

653 1980 0

#950337

11 Mar 2026 : Case report  China

Capsaicin-Triggered Vaginal Burning Due to Obstructed Rectovaginal Fistula: A Rare Case of Perineal Coproliths

Yujiao Wu, Weizheng Huang, Yong Wen, Cengzi Huang, Yaling Li, Jun Li

DOI: 10.12659/AJCR.950337

Am J Case Rep 2026; 27:e950337

850 1,772 0

#950337

11 Mar 2026 : Case report  China

Capsaicin-Triggered Vaginal Burning Due to Obstructed Rectovaginal Fistula: A Rare Case of Perineal Coproliths

Yujiao Wu, Weizheng Huang, Yong Wen, Cengzi Huang, Yaling Li, Jun Li

DOI: 10.12659/AJCR.950337

Am J Case Rep 2026; 27:e950337

850 1772 0

#951421

11 Mar 2026 : Case report  Saudi Arabia

Unrepaired Truncus Arteriosus Type 1 With Eisenmenger Syndrome and Recurrent Embolic Strokes: An Adult Case Report

Osama A. Abdulrahman, Mohammad F. Babgi, Jameel T. Alrefai, Atiqah H. Alfahmi, Shaimaa H. Oraif, Nada Bakhsh, Fatma Aboul-Enein ORCID logo, Ahemd M. Samman

DOI: 10.12659/AJCR.951421

Am J Case Rep 2026; 27:e951421

807 1,286 0

#951421

11 Mar 2026 : Case report  Saudi Arabia

Unrepaired Truncus Arteriosus Type 1 With Eisenmenger Syndrome and Recurrent Embolic Strokes: An Adult Case Report

Osama A. Abdulrahman, Mohammad F. Babgi, Jameel T. Alrefai, Atiqah H. Alfahmi, Shaimaa H. Oraif, Nada Bakhsh, Fatma Aboul-Enein ORCID logo, Ahemd M. Samman

DOI: 10.12659/AJCR.951421

Am J Case Rep 2026; 27:e951421

807 1286 0

#950412

10 Mar 2026 : Case report  USA

Peripheral Neuropathy Linked to Recreational Nitrous Oxide Use: A Case Report

Jeun Jun, Peter Aldo Giammanco ORCID logo, Jack J. Haslett ORCID logo, Andres Duran, Johanna L. Rosenthal

DOI: 10.12659/AJCR.950412

Am J Case Rep 2026; 27:e950412

810 3,864 0

#950412

10 Mar 2026 : Case report  USA

Peripheral Neuropathy Linked to Recreational Nitrous Oxide Use: A Case Report

Jeun Jun, Peter Aldo Giammanco ORCID logo, Jack J. Haslett ORCID logo, Andres Duran, Johanna L. Rosenthal

DOI: 10.12659/AJCR.950412

Am J Case Rep 2026; 27:e950412

810 3864 0

#950992

09 Mar 2026 : Case report  China

Recurrent Eosinophilic Pancreatitis With Eosinophilic Gastroenteritis: A Case Report

Xinyu Li, Donglei Zhang, Yanchen Li, Kunning Zhang, Ning Li

DOI: 10.12659/AJCR.950992

Am J Case Rep 2026; 27:e950992

687 1,896 0

#950992

09 Mar 2026 : Case report  China

Recurrent Eosinophilic Pancreatitis With Eosinophilic Gastroenteritis: A Case Report

Xinyu Li, Donglei Zhang, Yanchen Li, Kunning Zhang, Ning Li

DOI: 10.12659/AJCR.950992

Am J Case Rep 2026; 27:e950992

687 1896 0

#950857

07 Mar 2026 : Case report  Norway

Cryoglobulinemia Type II: Sustained Remission After B-Cell–Directed Therapy

Sara Giæver Suul ORCID logo, Ann Kristin Kvam, Malu Lian Hestdalen, Ulla Randen ORCID logo, Øyvind Midtvedt, Geir E. Tjønnfjord

DOI: 10.12659/AJCR.950857

Am J Case Rep 2026; 27:e950857

684 1,669 0

#950857

07 Mar 2026 : Case report  Norway

Cryoglobulinemia Type II: Sustained Remission After B-Cell–Directed Therapy

Sara Giæver Suul ORCID logo, Ann Kristin Kvam, Malu Lian Hestdalen, Ulla Randen ORCID logo, Øyvind Midtvedt, Geir E. Tjønnfjord

DOI: 10.12659/AJCR.950857

Am J Case Rep 2026; 27:e950857

684 1669 0

#950600

08 Mar 2026 : Case report  Saudi Arabia

Ruptured Pericardial Hydatid Cyst Causing Mitral Annulus Distortion With Severe Mitral Regurgitation and Tamponade-like Symptoms: A Case Report

Abdelrahman Jamiel ORCID logo, Shaimaa Mohamed ORCID logo, Norah Khalid Alobaid, Khalid A. Mohamed, Amjad M.A. Ahmed ORCID logo, Mohammad Salman Mohammad

DOI: 10.12659/AJCR.950600

Am J Case Rep 2026; 27:e950600

661 1,133 0

#950600

08 Mar 2026 : Case report  Saudi Arabia

Ruptured Pericardial Hydatid Cyst Causing Mitral Annulus Distortion With Severe Mitral Regurgitation and Tamponade-like Symptoms: A Case Report

Abdelrahman Jamiel ORCID logo, Shaimaa Mohamed ORCID logo, Norah Khalid Alobaid, Khalid A. Mohamed, Amjad M.A. Ahmed ORCID logo, Mohammad Salman Mohammad

DOI: 10.12659/AJCR.950600

Am J Case Rep 2026; 27:e950600

661 1133 0

#951172

06 Mar 2026 : Case report  China

Multifocal Digital Squamous Cell Carcinoma With Sarcoma Differentiation: A Case Report

Yingling Xiang, Liuchang Tan

DOI: 10.12659/AJCR.951172

Am J Case Rep 2026; 27:e951172

732 2,009 0

#951172

06 Mar 2026 : Case report  China

Multifocal Digital Squamous Cell Carcinoma With Sarcoma Differentiation: A Case Report

Yingling Xiang, Liuchang Tan

DOI: 10.12659/AJCR.951172

Am J Case Rep 2026; 27:e951172

732 2009 0

#950406

06 Mar 2026 : Case report  France

Intraoperative Discovery of Permanent Gluteal Filler During Implant Revision: A Case Report on Surgical Adaptation and Risk Awareness

Vivien Moris ORCID logo

DOI: 10.12659/AJCR.950406

Am J Case Rep 2026; 27:e950406

748 1,905 0

#950406

06 Mar 2026 : Case report  France

Intraoperative Discovery of Permanent Gluteal Filler During Implant Revision: A Case Report on Surgical Adaptation and Risk Awareness

Vivien Moris ORCID logo

DOI: 10.12659/AJCR.950406

Am J Case Rep 2026; 27:e950406

748 1905 0

In Press

Case report  Brazil

Image-Guided Cervicotomy and Recurrent Laryngeal Nerve Reinnervation in Zone II Glass Neck Trauma: A Case R...

Am J Case Rep In Press; DOI: 10.12659/AJCR.954178  

Case report  USA

When Infection Mimics Vasculitis: Hydralazine-Induced ANCA-Associated Crescentic Glomerulonephritis in the ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.954110  

Case report  China

Treatment of External Auditory Canal Hemangioma by Surgical Excision and Flap Reconstruction: 2 Case Reports

Am J Case Rep In Press; DOI: 10.12659/AJCR.953469  

Case report  Japan

Parenchymal Injury Caused by Complete Migration of a Bone of Japanese Horse Mackerel Within the Pancreatic ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.954338  

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923