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Challenging differential diagnosis

#949742

29 Dec 2025 : Case report  Brazil

Rapidly Progressive Disseminated Bacillus Calmette-Guérin Infection (BCGitis) in a 3-Month-Old Infant Without Immunodeficiency: A Case Report

Nathalya Queiroz Perillo, Taynara Heliodoro ORCID logo, Leandro Azevedo De Camargo, Melissa Ameloti Gomes Avelino, Fayez Bahmad Jr.

DOI: 10.12659/AJCR.949742

Am J Case Rep 2025; 26:e949742

896 2,154 0

#949742

29 Dec 2025 : Case report  Brazil

Rapidly Progressive Disseminated Bacillus Calmette-Guérin Infection (BCGitis) in a 3-Month-Old Infant Without Immunodeficiency: A Case Report

Nathalya Queiroz Perillo, Taynara Heliodoro ORCID logo, Leandro Azevedo De Camargo, Melissa Ameloti Gomes Avelino, Fayez Bahmad Jr.

DOI: 10.12659/AJCR.949742

Am J Case Rep 2025; 26:e949742

896 2154 0

#949591

27 Dec 2025 : Case report  Italy

In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Features of Corneal Pseudodendritic Lesions in Hereditary Tyrosinemia Type 1

Rocco Bruno ORCID logo, Sarah Donatelli, Leonardo Mastropasqua ORCID logo, Mario Nubile

DOI: 10.12659/AJCR.949591

Am J Case Rep 2025; 26:e949591

896 1,473 0

#949591

27 Dec 2025 : Case report  Italy

In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Features of Corneal Pseudodendritic Lesions in Hereditary Tyrosinemia Type 1

Rocco Bruno ORCID logo, Sarah Donatelli, Leonardo Mastropasqua ORCID logo, Mario Nubile

DOI: 10.12659/AJCR.949591

Am J Case Rep 2025; 26:e949591

896 1473 0

#950684

26 Dec 2025 : Case report  USA

Primary Well-Differentiated Neuroendocrine Tumor of the Breast: A Case Report and Literature Review

Sanjna Sai Gudena, Nilesh Digvijay Kashikar, Matthew Charles Wakefield

DOI: 10.12659/AJCR.950684

Am J Case Rep 2025; 26:e950684

1,012 3,079 0

#950684

26 Dec 2025 : Case report  USA

Primary Well-Differentiated Neuroendocrine Tumor of the Breast: A Case Report and Literature Review

Sanjna Sai Gudena, Nilesh Digvijay Kashikar, Matthew Charles Wakefield

DOI: 10.12659/AJCR.950684

Am J Case Rep 2025; 26:e950684

1012 3079 0

#950626

25 Dec 2025 : Case report  Jordan

The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia

Moath Fateh ORCID logo, Tariq Albweitel, Ahmad Odeh, Sarah Ghaith

DOI: 10.12659/AJCR.950626

Am J Case Rep 2025; 26:e950626

1,117 4,126 0

#950626

25 Dec 2025 : Case report  Jordan

The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia

Moath Fateh ORCID logo, Tariq Albweitel, Ahmad Odeh, Sarah Ghaith

DOI: 10.12659/AJCR.950626

Am J Case Rep 2025; 26:e950626

1117 4126 0

#949879

24 Dec 2025 : Case report  Greece

Bronchial Arteriovenous Malformation Detection Prior to Catheter Ablation for Paroxysmal Atrial Flutter and Fibrillation: A Case Report

Alexandra Arvanitaki ORCID logo, Marios Georgios Bantidos ORCID logo, Theodora Zaglavara ORCID logo, Lydia Kalogeropoulou ORCID logo, Athanasios Samaras ORCID logo, Athina Nasoufidou ORCID logo, Efstratios Karagiannidis ORCID logo, Georgios Stavropoulos ORCID logo, Apostolos Tzikas ORCID logo, Nikolaos Fragakis ORCID logo

DOI: 10.12659/AJCR.949879

Am J Case Rep 2025; 26:e949879

1,013 1,800 0

#949879

24 Dec 2025 : Case report  Greece

Bronchial Arteriovenous Malformation Detection Prior to Catheter Ablation for Paroxysmal Atrial Flutter and Fibrillation: A Case Report

Alexandra Arvanitaki ORCID logo, Marios Georgios Bantidos ORCID logo, Theodora Zaglavara ORCID logo, Lydia Kalogeropoulou ORCID logo, Athanasios Samaras ORCID logo, Athina Nasoufidou ORCID logo, Efstratios Karagiannidis ORCID logo, Georgios Stavropoulos ORCID logo, Apostolos Tzikas ORCID logo, Nikolaos Fragakis ORCID logo

DOI: 10.12659/AJCR.949879

Am J Case Rep 2025; 26:e949879

1013 1800 0

#949642

23 Dec 2025 : Case report  Japan

Platypnea-Orthodeoxia Syndrome Associated With a Right-to-Left Cardiac Shunt Detected by Lung Perfusion Scintigraphy

Yusuke Nakano ORCID logo, Hirohiko Ando, Akinori Satake, Reiji Goto, Kentaro Mukai, Tetsuya Amano

DOI: 10.12659/AJCR.949642

Am J Case Rep 2025; 26:e949642

985 2,179 0

#949642

23 Dec 2025 : Case report  Japan

Platypnea-Orthodeoxia Syndrome Associated With a Right-to-Left Cardiac Shunt Detected by Lung Perfusion Scintigraphy

Yusuke Nakano ORCID logo, Hirohiko Ando, Akinori Satake, Reiji Goto, Kentaro Mukai, Tetsuya Amano

DOI: 10.12659/AJCR.949642

Am J Case Rep 2025; 26:e949642

985 2179 0

#949554

23 Dec 2025 : Case report  Serbia

Low-Grade Appendiceal Mucinous Neoplasm as an Incidental Finding During Cesarean Section: A Case Report

Vesna Paunovic ORCID logo, Tomislav Paunovic, Aleksa Jokic ORCID logo, Bojana S. Ivic ORCID logo, Aleksandra Petrovic, Nina Pejic ORCID logo, Milos Stulic ORCID logo, Jelena Martinov Nestorov, Jovan Jevtic ORCID logo, Zeljko Vlaisavljevic ORCID logo

DOI: 10.12659/AJCR.949554

Am J Case Rep 2025; 26:e949554

1,285 2,863 0

#949554

23 Dec 2025 : Case report  Serbia

Low-Grade Appendiceal Mucinous Neoplasm as an Incidental Finding During Cesarean Section: A Case Report

Vesna Paunovic ORCID logo, Tomislav Paunovic, Aleksa Jokic ORCID logo, Bojana S. Ivic ORCID logo, Aleksandra Petrovic, Nina Pejic ORCID logo, Milos Stulic ORCID logo, Jelena Martinov Nestorov, Jovan Jevtic ORCID logo, Zeljko Vlaisavljevic ORCID logo

DOI: 10.12659/AJCR.949554

Am J Case Rep 2025; 26:e949554

1285 2863 0

#951223

22 Dec 2025 : Case report  China

Asymptomatic Lung Adenocarcinoma With Cardiac Metastasis at Initial Diagnosis: A Case Report

Tianyu Jin, Yongzhong Jiang, Yong Song

DOI: 10.12659/AJCR.951223

Am J Case Rep 2025; 26:e951223

1,051 3,155 0

#951223

22 Dec 2025 : Case report  China

Asymptomatic Lung Adenocarcinoma With Cardiac Metastasis at Initial Diagnosis: A Case Report

Tianyu Jin, Yongzhong Jiang, Yong Song

DOI: 10.12659/AJCR.951223

Am J Case Rep 2025; 26:e951223

1051 3155 0

#947770

21 Dec 2025 : Case report  China

Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer

Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye

DOI: 10.12659/AJCR.947770

Am J Case Rep 2025; 26:e947770

1,266 2,803 0

#947770

21 Dec 2025 : Case report  China

Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer

Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye

DOI: 10.12659/AJCR.947770

Am J Case Rep 2025; 26:e947770

1266 2803 0

#945090

20 Dec 2025 : Case report  French Guiana

Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment

Ugo Françoise ORCID logo, Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle ORCID logo, Paul Le Turnier

DOI: 10.12659/AJCR.945090

Am J Case Rep 2025; 26:e945090

1,329 2,888 0

#945090

20 Dec 2025 : Case report  French Guiana

Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment

Ugo Françoise ORCID logo, Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle ORCID logo, Paul Le Turnier

DOI: 10.12659/AJCR.945090

Am J Case Rep 2025; 26:e945090

1329 2888 0

#950574

20 Dec 2025 : Case report  China

Diagnostic Challenges of Abdominal Tumors Without Typical Imaging Features: From Misdiagnosis of Pancreatic Cystadenoma to Adrenal Pheochromocytoma and the Intraoperative Response

Haoyang Huang ORCID logo, Dingwei Xu ORCID logo, Zhangbin Chen, Jie Huang

DOI: 10.12659/AJCR.950574

Am J Case Rep 2025; 26:e950574

957 1,424 0

#950574

20 Dec 2025 : Case report  China

Diagnostic Challenges of Abdominal Tumors Without Typical Imaging Features: From Misdiagnosis of Pancreatic Cystadenoma to Adrenal Pheochromocytoma and the Intraoperative Response

Haoyang Huang ORCID logo, Dingwei Xu ORCID logo, Zhangbin Chen, Jie Huang

DOI: 10.12659/AJCR.950574

Am J Case Rep 2025; 26:e950574

957 1424 0

#950208

19 Dec 2025 : Case report  USA

Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis

Meghan Stevenson, Naveed Younis

DOI: 10.12659/AJCR.950208

Am J Case Rep 2025; 26:e950208

1,024 2,039 0

#950208

19 Dec 2025 : Case report  USA

Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis

Meghan Stevenson, Naveed Younis

DOI: 10.12659/AJCR.950208

Am J Case Rep 2025; 26:e950208

1024 2039 0

#951048

19 Dec 2025 : Case report  China

Primary Orbital Lymphoma Manifesting as Increased Intraocular Pressure: A Case Report

Miaomiao Sun, Zhaohui Xiong, Yincong Xu, Zhongyou Zhou, Jiale Wu, Jiangzhou Han, Lina Zhao

DOI: 10.12659/AJCR.951048

Am J Case Rep 2025; 26:e951048

1,155 2,755 0

#951048

19 Dec 2025 : Case report  China

Primary Orbital Lymphoma Manifesting as Increased Intraocular Pressure: A Case Report

Miaomiao Sun, Zhaohui Xiong, Yincong Xu, Zhongyou Zhou, Jiale Wu, Jiangzhou Han, Lina Zhao

DOI: 10.12659/AJCR.951048

Am J Case Rep 2025; 26:e951048

1155 2755 0

#949233

18 Dec 2025 : Case report  Japan

Drug-Induced Lupus Erythematosus After 14 Years of Carbamazepine Use in a Patient With Neuromyelitis Optica Spectrum Disorder: A Case Report

Naho Ayuzawa-Takeda, Keisuke Saito, Hidetoshi Yanagida, Tomoko Oeda

DOI: 10.12659/AJCR.949233

Am J Case Rep 2025; 26:e949233

1,336 4,552 0

#949233

18 Dec 2025 : Case report  Japan

Drug-Induced Lupus Erythematosus After 14 Years of Carbamazepine Use in a Patient With Neuromyelitis Optica Spectrum Disorder: A Case Report

Naho Ayuzawa-Takeda, Keisuke Saito, Hidetoshi Yanagida, Tomoko Oeda

DOI: 10.12659/AJCR.949233

Am J Case Rep 2025; 26:e949233

1336 4552 0

#949788

17 Dec 2025 : Case report  USA

COVID-19-Associated MDA5-Mediated Necrotizing Myositis

Sarah Steadman, Amit Sikder, Harsh R. Desai ORCID logo, Bradley Collins ORCID logo, Tiffany Baker, Julie Worthington

DOI: 10.12659/AJCR.949788

Am J Case Rep 2025; 26:e949788

1,668 3,587 0

#949788

17 Dec 2025 : Case report  USA

COVID-19-Associated MDA5-Mediated Necrotizing Myositis

Sarah Steadman, Amit Sikder, Harsh R. Desai ORCID logo, Bradley Collins ORCID logo, Tiffany Baker, Julie Worthington

DOI: 10.12659/AJCR.949788

Am J Case Rep 2025; 26:e949788

1668 3587 0

#950597

17 Dec 2025 : Case report  Japan

Splenic Hamartoma Diagnosed and Treated by Laparoscopic Splenectomy Associated With a Minimal Suprapubic Approach

Hikaru Ohtani, Tomohide Hori, Shigeki Nakayama, Satoru Umegae, Takao Iwanaga, Ryutaro Nishikawa, Takahiro Shimoyama, Sakurako Suzuki, Shigehito Nakashima, Takayuki Yamamoto

DOI: 10.12659/AJCR.950597

Am J Case Rep 2025; 26:e950597

932 1,671 0

#950597

17 Dec 2025 : Case report  Japan

Splenic Hamartoma Diagnosed and Treated by Laparoscopic Splenectomy Associated With a Minimal Suprapubic Approach

Hikaru Ohtani, Tomohide Hori, Shigeki Nakayama, Satoru Umegae, Takao Iwanaga, Ryutaro Nishikawa, Takahiro Shimoyama, Sakurako Suzuki, Shigehito Nakashima, Takayuki Yamamoto

DOI: 10.12659/AJCR.950597

Am J Case Rep 2025; 26:e950597

932 1671 0

#949052

16 Dec 2025 : Case report  China

Electronic Gastroscopy in Identifying Hidden Tonsillar Foreign Bodies: A Case of a Completely Embedded Sunflower Seed Shell

Deng Liang ORCID logo

DOI: 10.12659/AJCR.949052

Am J Case Rep 2025; 26:e949052

951 1,766 0

#949052

16 Dec 2025 : Case report  China

Electronic Gastroscopy in Identifying Hidden Tonsillar Foreign Bodies: A Case of a Completely Embedded Sunflower Seed Shell

Deng Liang ORCID logo

DOI: 10.12659/AJCR.949052

Am J Case Rep 2025; 26:e949052

951 1766 0

#949999

16 Dec 2025 : Case report  USA

Subdural Empyema and Pneumocephalus From Chronic Polypoid Sinusitis in an Elderly Woman With Rapid Neurological Recovery: A Report of a Rare Case

John Martinez, Elizabeth Nagidi, Mark Rigby ORCID logo, Lina Ataya, Aftab Macksood, Ghiath Bayasi, Kelsee Rotondo

DOI: 10.12659/AJCR.949999

Am J Case Rep 2025; 26:e949999

1,057 2,210 0

#949999

16 Dec 2025 : Case report  USA

Subdural Empyema and Pneumocephalus From Chronic Polypoid Sinusitis in an Elderly Woman With Rapid Neurological Recovery: A Report of a Rare Case

John Martinez, Elizabeth Nagidi, Mark Rigby ORCID logo, Lina Ataya, Aftab Macksood, Ghiath Bayasi, Kelsee Rotondo

DOI: 10.12659/AJCR.949999

Am J Case Rep 2025; 26:e949999

1057 2210 0

#949034

15 Dec 2025 : Case report  China

Primary Pulmonary Osteosarcoma Presenting as a 1.7-cm Subpleural Nodule in a 61-Year-Old Man: A Case Report

Xin Yang, Wen Guang Zhao, Chao Gao, Sheng Lin

DOI: 10.12659/AJCR.949034

Am J Case Rep 2025; 26:e949034

1,018 1,518 0

#949034

15 Dec 2025 : Case report  China

Primary Pulmonary Osteosarcoma Presenting as a 1.7-cm Subpleural Nodule in a 61-Year-Old Man: A Case Report

Xin Yang, Wen Guang Zhao, Chao Gao, Sheng Lin

DOI: 10.12659/AJCR.949034

Am J Case Rep 2025; 26:e949034

1018 1518 0

#948950

15 Dec 2025 : Case report  Saudi Arabia

Compartment Syndrome Secondary to Phlegmasia Cerulea Dolens in a Patient With Crohn’s Disease

Saad Mohammed Alshahrani ORCID logo, Raghad Ibrahim Alkoblan, Reem Abdulaziz Alturki, Shahad Mohammed Alashgar

DOI: 10.12659/AJCR.948950

Am J Case Rep 2025; 26:e948950

976 1,563 0

#948950

15 Dec 2025 : Case report  Saudi Arabia

Compartment Syndrome Secondary to Phlegmasia Cerulea Dolens in a Patient With Crohn’s Disease

Saad Mohammed Alshahrani ORCID logo, Raghad Ibrahim Alkoblan, Reem Abdulaziz Alturki, Shahad Mohammed Alashgar

DOI: 10.12659/AJCR.948950

Am J Case Rep 2025; 26:e948950

976 1563 0

#949936

14 Dec 2025 : Case report  Saudi Arabia

Bruton’s Agammaglobulinemia: Case Series and Literature Review From King Fahad Central Hospital, Jizan, Saudi Arabia

Ahmed Shamakhi, Nabil Dhayhi, Shatha Matabi, Manal Maashi, Abdullah Dhaifallah Hamdi, Bander Ali, Fadhel Hazazi, Abdullah H. Alhamoud

DOI: 10.12659/AJCR.949936

Am J Case Rep 2025; 26:e949936

1,419 4,284 0

#949936

14 Dec 2025 : Case report  Saudi Arabia

Bruton’s Agammaglobulinemia: Case Series and Literature Review From King Fahad Central Hospital, Jizan, Saudi Arabia

Ahmed Shamakhi, Nabil Dhayhi, Shatha Matabi, Manal Maashi, Abdullah Dhaifallah Hamdi, Bander Ali, Fadhel Hazazi, Abdullah H. Alhamoud

DOI: 10.12659/AJCR.949936

Am J Case Rep 2025; 26:e949936

1419 4284 0

#947774

12 Dec 2025 : Case report  Romania

Unpredictable Evolution of Pilocytic Astrocytoma in Adults: A Case Series and Diagnostic Challenges

Anamaria Sincu, Cristian-Ionut Orasanu ORCID logo, Raluca Ioana Voda ORCID logo, Madalina Bosoteanu ORCID logo, Manuela Enciu ORCID logo, Sorin Vamesu ORCID logo, Sinziana Andra Ghitoi, Mariana Deacu ORCID logo

DOI: 10.12659/AJCR.947774

Am J Case Rep 2025; 26:e947774

1,225 5,913 0

#947774

12 Dec 2025 : Case report  Romania

Unpredictable Evolution of Pilocytic Astrocytoma in Adults: A Case Series and Diagnostic Challenges

Anamaria Sincu, Cristian-Ionut Orasanu ORCID logo, Raluca Ioana Voda ORCID logo, Madalina Bosoteanu ORCID logo, Manuela Enciu ORCID logo, Sorin Vamesu ORCID logo, Sinziana Andra Ghitoi, Mariana Deacu ORCID logo

DOI: 10.12659/AJCR.947774

Am J Case Rep 2025; 26:e947774

1225 5913 0

#948020

11 Dec 2025 : Case report  Poland

A 60-Year-Old Man with an Incidental Finding of an Asymptomatic Aneurysm of the Right Gastroepiploic Artery Managed by Laparoscopic Resection

Maksymilian Baryła ORCID logo, Paweł Kazimierz Ziemiański ORCID logo

DOI: 10.12659/AJCR.948020

Am J Case Rep 2025; 26:e948020

936 1,498 0

#948020

11 Dec 2025 : Case report  Poland

A 60-Year-Old Man with an Incidental Finding of an Asymptomatic Aneurysm of the Right Gastroepiploic Artery Managed by Laparoscopic Resection

Maksymilian Baryła ORCID logo, Paweł Kazimierz Ziemiański ORCID logo

DOI: 10.12659/AJCR.948020

Am J Case Rep 2025; 26:e948020

936 1498 0

#949587

10 Dec 2025 : Case report  Palestinian Territory, Occupied

Isolated Transient Neonatal Ascites in a Preterm Infant Born to a Mother with Mirror Syndrome: A Case Report

Mo’ath Abu Hamdeh, Rasmea Mohammad Asad, Zeidan Abdalsalam, Mohammad Maraqah, Lema Saleh Khaled Jaber, Mai M.R. Rostom, Majed Methqal Abu Jaish

DOI: 10.12659/AJCR.949587

Am J Case Rep 2025; 26:e949587

1,197 2,927 0

#949587

10 Dec 2025 : Case report  Palestinian Territory, Occupied

Isolated Transient Neonatal Ascites in a Preterm Infant Born to a Mother with Mirror Syndrome: A Case Report

Mo’ath Abu Hamdeh, Rasmea Mohammad Asad, Zeidan Abdalsalam, Mohammad Maraqah, Lema Saleh Khaled Jaber, Mai M.R. Rostom, Majed Methqal Abu Jaish

DOI: 10.12659/AJCR.949587

Am J Case Rep 2025; 26:e949587

1197 2927 0

#949018

09 Dec 2025 : Case report  China

A Rare Case of Emphysematous Pyelonephritis Following Retrograde Intrarenal Surgery in an Elderly Man

Weiyong Zhong ORCID logo, Feihong Xu ORCID logo, Shujiang Ye, Yu Liu, Wei Zhao, Zhenquan Lu, Lin Xiong, Xiang Xu

DOI: 10.12659/AJCR.949018

Am J Case Rep 2025; 26:e949018

949 1,825 0

#949018

09 Dec 2025 : Case report  China

A Rare Case of Emphysematous Pyelonephritis Following Retrograde Intrarenal Surgery in an Elderly Man

Weiyong Zhong ORCID logo, Feihong Xu ORCID logo, Shujiang Ye, Yu Liu, Wei Zhao, Zhenquan Lu, Lin Xiong, Xiang Xu

DOI: 10.12659/AJCR.949018

Am J Case Rep 2025; 26:e949018

949 1825 0

In Press

Case report  Japan

Spontaneous Closure of a Secondary Macular Hole After Rhegmatogenous Retinal Detachment Repair With Membran...

Am J Case Rep In Press; DOI: 10.12659/AJCR.954405  

Case report  Denmark

Preoxygenation With Tube-Tip-in-Mouth Method: A Case Report of a Feasible Alternative for a Patient With Cl...

Am J Case Rep In Press; DOI: 10.12659/AJCR.953611  

Case report  Greece

Negative Pressure Wound Therapy After Extensive Debridement of a Pediatric Plantar Puncture-Wound Infection...

Am J Case Rep In Press; DOI: 10.12659/AJCR.954016  

Case report  Greece

Schwannoma of the Transverse Mesocolon: A Neurogenic Rarity

Am J Case Rep In Press; DOI: 10.12659/AJCR.954891  

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923