Challenging differential diagnosis

29 Dec 2025 : Case report
Rapidly Progressive Disseminated Bacillus Calmette-Guérin Infection (BCGitis) in a 3-Month-Old Infant Without Immunodeficiency: A Case Report
Nathalya Queiroz Perillo, Taynara Heliodoro
, Leandro Azevedo De Camargo, Melissa Ameloti Gomes Avelino, Fayez Bahmad Jr.
DOI: 10.12659/AJCR.949742
Am J Case Rep 2025; 26:e949742
896 2,154 0

29 Dec 2025 : Case report
Rapidly Progressive Disseminated Bacillus Calmette-Guérin Infection (BCGitis) in a 3-Month-Old Infant Without Immunodeficiency: A Case Report
Nathalya Queiroz Perillo, Taynara Heliodoro
, Leandro Azevedo De Camargo, Melissa Ameloti Gomes Avelino, Fayez Bahmad Jr.
DOI: 10.12659/AJCR.949742
Am J Case Rep 2025; 26:e949742
896 2154 0

27 Dec 2025 : Case report
In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Features of Corneal Pseudodendritic Lesions in Hereditary Tyrosinemia Type 1
Rocco Bruno
, Sarah Donatelli, Leonardo Mastropasqua
, Mario Nubile
DOI: 10.12659/AJCR.949591
Am J Case Rep 2025; 26:e949591
896 1,473 0

27 Dec 2025 : Case report
In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Features of Corneal Pseudodendritic Lesions in Hereditary Tyrosinemia Type 1
Rocco Bruno
, Sarah Donatelli, Leonardo Mastropasqua
, Mario Nubile
DOI: 10.12659/AJCR.949591
Am J Case Rep 2025; 26:e949591
896 1473 0

26 Dec 2025 : Case report
Primary Well-Differentiated Neuroendocrine Tumor of the Breast: A Case Report and Literature Review
Sanjna Sai Gudena, Nilesh Digvijay Kashikar, Matthew Charles Wakefield
DOI: 10.12659/AJCR.950684
Am J Case Rep 2025; 26:e950684
1,012 3,079 0

26 Dec 2025 : Case report
Primary Well-Differentiated Neuroendocrine Tumor of the Breast: A Case Report and Literature Review
Sanjna Sai Gudena, Nilesh Digvijay Kashikar, Matthew Charles Wakefield
DOI: 10.12659/AJCR.950684
Am J Case Rep 2025; 26:e950684
1012 3079 0

25 Dec 2025 : Case report
The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia
Moath Fateh
, Tariq Albweitel, Ahmad Odeh, Sarah Ghaith
DOI: 10.12659/AJCR.950626
Am J Case Rep 2025; 26:e950626
1,117 4,126 0

25 Dec 2025 : Case report
The Silent Surge: A Case of Rhabdomyolysis-Induced Hypercalcemia
Moath Fateh
, Tariq Albweitel, Ahmad Odeh, Sarah Ghaith
DOI: 10.12659/AJCR.950626
Am J Case Rep 2025; 26:e950626
1117 4126 0

24 Dec 2025 : Case report
Bronchial Arteriovenous Malformation Detection Prior to Catheter Ablation for Paroxysmal Atrial Flutter and Fibrillation: A Case Report
Alexandra Arvanitaki
, Marios Georgios Bantidos
, Theodora Zaglavara
, Lydia Kalogeropoulou
, Athanasios Samaras
, Athina Nasoufidou
, Efstratios Karagiannidis
, Georgios Stavropoulos
, Apostolos Tzikas
, Nikolaos Fragakis
DOI: 10.12659/AJCR.949879
Am J Case Rep 2025; 26:e949879
1,013 1,800 0

24 Dec 2025 : Case report
Bronchial Arteriovenous Malformation Detection Prior to Catheter Ablation for Paroxysmal Atrial Flutter and Fibrillation: A Case Report
Alexandra Arvanitaki
, Marios Georgios Bantidos
, Theodora Zaglavara
, Lydia Kalogeropoulou
, Athanasios Samaras
, Athina Nasoufidou
, Efstratios Karagiannidis
, Georgios Stavropoulos
, Apostolos Tzikas
, Nikolaos Fragakis
DOI: 10.12659/AJCR.949879
Am J Case Rep 2025; 26:e949879
1013 1800 0

23 Dec 2025 : Case report
Platypnea-Orthodeoxia Syndrome Associated With a Right-to-Left Cardiac Shunt Detected by Lung Perfusion Scintigraphy
Yusuke Nakano
, Hirohiko Ando, Akinori Satake, Reiji Goto, Kentaro Mukai, Tetsuya Amano
DOI: 10.12659/AJCR.949642
Am J Case Rep 2025; 26:e949642
985 2,179 0

23 Dec 2025 : Case report
Platypnea-Orthodeoxia Syndrome Associated With a Right-to-Left Cardiac Shunt Detected by Lung Perfusion Scintigraphy
Yusuke Nakano
, Hirohiko Ando, Akinori Satake, Reiji Goto, Kentaro Mukai, Tetsuya Amano
DOI: 10.12659/AJCR.949642
Am J Case Rep 2025; 26:e949642
985 2179 0

23 Dec 2025 : Case report
Low-Grade Appendiceal Mucinous Neoplasm as an Incidental Finding During Cesarean Section: A Case Report
Vesna Paunovic
, Tomislav Paunovic, Aleksa Jokic
, Bojana S. Ivic
, Aleksandra Petrovic, Nina Pejic
, Milos Stulic
, Jelena Martinov Nestorov, Jovan Jevtic
, Zeljko Vlaisavljevic
DOI: 10.12659/AJCR.949554
Am J Case Rep 2025; 26:e949554
1,285 2,863 0

23 Dec 2025 : Case report
Low-Grade Appendiceal Mucinous Neoplasm as an Incidental Finding During Cesarean Section: A Case Report
Vesna Paunovic
, Tomislav Paunovic, Aleksa Jokic
, Bojana S. Ivic
, Aleksandra Petrovic, Nina Pejic
, Milos Stulic
, Jelena Martinov Nestorov, Jovan Jevtic
, Zeljko Vlaisavljevic
DOI: 10.12659/AJCR.949554
Am J Case Rep 2025; 26:e949554
1285 2863 0

22 Dec 2025 : Case report
Asymptomatic Lung Adenocarcinoma With Cardiac Metastasis at Initial Diagnosis: A Case Report
Tianyu Jin, Yongzhong Jiang, Yong Song
DOI: 10.12659/AJCR.951223
Am J Case Rep 2025; 26:e951223
1,051 3,155 0

22 Dec 2025 : Case report
Asymptomatic Lung Adenocarcinoma With Cardiac Metastasis at Initial Diagnosis: A Case Report
Tianyu Jin, Yongzhong Jiang, Yong Song
DOI: 10.12659/AJCR.951223
Am J Case Rep 2025; 26:e951223
1051 3155 0

21 Dec 2025 : Case report
Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer
Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye
DOI: 10.12659/AJCR.947770
Am J Case Rep 2025; 26:e947770
1,266 2,803 0

21 Dec 2025 : Case report
Allergic Bronchopulmonary Aspergillosis Presenting With Pulmonary Solid Lesions and Elevated Serum Carcinoembryonic Antigen Mimicking Lung Cancer
Heling Wu, Tiange Qu, Shenwen Yi, Jun Xu, Fei Yu, Liang Ye
DOI: 10.12659/AJCR.947770
Am J Case Rep 2025; 26:e947770
1266 2803 0

20 Dec 2025 : Case report
Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment
Ugo Françoise
, Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle
, Paul Le Turnier
DOI: 10.12659/AJCR.945090
Am J Case Rep 2025; 26:e945090
1,329 2,888 0

20 Dec 2025 : Case report
Ethambutol-Associated Thrombocytopenia: A Rare Case Report of Drug-Induced Platelet Decline in Tuberculosis Treatment
Ugo Françoise
, Kim Henry, Mohamed Sidibe, Valérie Lalande, Clément Cholle
, Paul Le Turnier
DOI: 10.12659/AJCR.945090
Am J Case Rep 2025; 26:e945090
1329 2888 0

20 Dec 2025 : Case report
Diagnostic Challenges of Abdominal Tumors Without Typical Imaging Features: From Misdiagnosis of Pancreatic Cystadenoma to Adrenal Pheochromocytoma and the Intraoperative Response
Haoyang Huang
, Dingwei Xu
, Zhangbin Chen, Jie Huang
DOI: 10.12659/AJCR.950574
Am J Case Rep 2025; 26:e950574
957 1,424 0

20 Dec 2025 : Case report
Diagnostic Challenges of Abdominal Tumors Without Typical Imaging Features: From Misdiagnosis of Pancreatic Cystadenoma to Adrenal Pheochromocytoma and the Intraoperative Response
Haoyang Huang
, Dingwei Xu
, Zhangbin Chen, Jie Huang
DOI: 10.12659/AJCR.950574
Am J Case Rep 2025; 26:e950574
957 1424 0

19 Dec 2025 : Case report
Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis
Meghan Stevenson, Naveed Younis
DOI: 10.12659/AJCR.950208
Am J Case Rep 2025; 26:e950208
1,024 2,039 0

19 Dec 2025 : Case report
Concomitant Neurosarcoidosis and Cardiac Sarcoidosis: A Peculiar Path to Diagnosis
Meghan Stevenson, Naveed Younis
DOI: 10.12659/AJCR.950208
Am J Case Rep 2025; 26:e950208
1024 2039 0

19 Dec 2025 : Case report
Primary Orbital Lymphoma Manifesting as Increased Intraocular Pressure: A Case Report
Miaomiao Sun, Zhaohui Xiong, Yincong Xu, Zhongyou Zhou, Jiale Wu, Jiangzhou Han, Lina Zhao
DOI: 10.12659/AJCR.951048
Am J Case Rep 2025; 26:e951048
1,155 2,755 0

19 Dec 2025 : Case report
Primary Orbital Lymphoma Manifesting as Increased Intraocular Pressure: A Case Report
Miaomiao Sun, Zhaohui Xiong, Yincong Xu, Zhongyou Zhou, Jiale Wu, Jiangzhou Han, Lina Zhao
DOI: 10.12659/AJCR.951048
Am J Case Rep 2025; 26:e951048
1155 2755 0

18 Dec 2025 : Case report
Drug-Induced Lupus Erythematosus After 14 Years of Carbamazepine Use in a Patient With Neuromyelitis Optica Spectrum Disorder: A Case Report
Naho Ayuzawa-Takeda, Keisuke Saito, Hidetoshi Yanagida, Tomoko Oeda
DOI: 10.12659/AJCR.949233
Am J Case Rep 2025; 26:e949233
1,336 4,552 0

18 Dec 2025 : Case report
Drug-Induced Lupus Erythematosus After 14 Years of Carbamazepine Use in a Patient With Neuromyelitis Optica Spectrum Disorder: A Case Report
Naho Ayuzawa-Takeda, Keisuke Saito, Hidetoshi Yanagida, Tomoko Oeda
DOI: 10.12659/AJCR.949233
Am J Case Rep 2025; 26:e949233
1336 4552 0

17 Dec 2025 : Case report
COVID-19-Associated MDA5-Mediated Necrotizing Myositis
Sarah Steadman, Amit Sikder, Harsh R. Desai
, Bradley Collins
, Tiffany Baker, Julie Worthington
DOI: 10.12659/AJCR.949788
Am J Case Rep 2025; 26:e949788
1,668 3,587 0

17 Dec 2025 : Case report
COVID-19-Associated MDA5-Mediated Necrotizing Myositis
Sarah Steadman, Amit Sikder, Harsh R. Desai
, Bradley Collins
, Tiffany Baker, Julie Worthington
DOI: 10.12659/AJCR.949788
Am J Case Rep 2025; 26:e949788
1668 3587 0

17 Dec 2025 : Case report
Splenic Hamartoma Diagnosed and Treated by Laparoscopic Splenectomy Associated With a Minimal Suprapubic Approach
Hikaru Ohtani, Tomohide Hori, Shigeki Nakayama, Satoru Umegae, Takao Iwanaga, Ryutaro Nishikawa, Takahiro Shimoyama, Sakurako Suzuki, Shigehito Nakashima, Takayuki Yamamoto
DOI: 10.12659/AJCR.950597
Am J Case Rep 2025; 26:e950597
932 1,671 0

17 Dec 2025 : Case report
Splenic Hamartoma Diagnosed and Treated by Laparoscopic Splenectomy Associated With a Minimal Suprapubic Approach
Hikaru Ohtani, Tomohide Hori, Shigeki Nakayama, Satoru Umegae, Takao Iwanaga, Ryutaro Nishikawa, Takahiro Shimoyama, Sakurako Suzuki, Shigehito Nakashima, Takayuki Yamamoto
DOI: 10.12659/AJCR.950597
Am J Case Rep 2025; 26:e950597
932 1671 0

16 Dec 2025 : Case report
Electronic Gastroscopy in Identifying Hidden Tonsillar Foreign Bodies: A Case of a Completely Embedded Sunflower Seed Shell
DOI: 10.12659/AJCR.949052
Am J Case Rep 2025; 26:e949052
951 1,766 0

16 Dec 2025 : Case report
Electronic Gastroscopy in Identifying Hidden Tonsillar Foreign Bodies: A Case of a Completely Embedded Sunflower Seed Shell
DOI: 10.12659/AJCR.949052
Am J Case Rep 2025; 26:e949052
951 1766 0

16 Dec 2025 : Case report
Subdural Empyema and Pneumocephalus From Chronic Polypoid Sinusitis in an Elderly Woman With Rapid Neurological Recovery: A Report of a Rare Case
John Martinez, Elizabeth Nagidi, Mark Rigby
, Lina Ataya, Aftab Macksood, Ghiath Bayasi, Kelsee Rotondo
DOI: 10.12659/AJCR.949999
Am J Case Rep 2025; 26:e949999
1,057 2,210 0

16 Dec 2025 : Case report
Subdural Empyema and Pneumocephalus From Chronic Polypoid Sinusitis in an Elderly Woman With Rapid Neurological Recovery: A Report of a Rare Case
John Martinez, Elizabeth Nagidi, Mark Rigby
, Lina Ataya, Aftab Macksood, Ghiath Bayasi, Kelsee Rotondo
DOI: 10.12659/AJCR.949999
Am J Case Rep 2025; 26:e949999
1057 2210 0

15 Dec 2025 : Case report
Primary Pulmonary Osteosarcoma Presenting as a 1.7-cm Subpleural Nodule in a 61-Year-Old Man: A Case Report
Xin Yang, Wen Guang Zhao, Chao Gao, Sheng Lin
DOI: 10.12659/AJCR.949034
Am J Case Rep 2025; 26:e949034
1,018 1,518 0

15 Dec 2025 : Case report
Primary Pulmonary Osteosarcoma Presenting as a 1.7-cm Subpleural Nodule in a 61-Year-Old Man: A Case Report
Xin Yang, Wen Guang Zhao, Chao Gao, Sheng Lin
DOI: 10.12659/AJCR.949034
Am J Case Rep 2025; 26:e949034
1018 1518 0

15 Dec 2025 : Case report
Compartment Syndrome Secondary to Phlegmasia Cerulea Dolens in a Patient With Crohn’s Disease
Saad Mohammed Alshahrani
, Raghad Ibrahim Alkoblan, Reem Abdulaziz Alturki, Shahad Mohammed Alashgar
DOI: 10.12659/AJCR.948950
Am J Case Rep 2025; 26:e948950
976 1,563 0

15 Dec 2025 : Case report
Compartment Syndrome Secondary to Phlegmasia Cerulea Dolens in a Patient With Crohn’s Disease
Saad Mohammed Alshahrani
, Raghad Ibrahim Alkoblan, Reem Abdulaziz Alturki, Shahad Mohammed Alashgar
DOI: 10.12659/AJCR.948950
Am J Case Rep 2025; 26:e948950
976 1563 0

14 Dec 2025 : Case report
Bruton’s Agammaglobulinemia: Case Series and Literature Review From King Fahad Central Hospital, Jizan, Saudi Arabia
Ahmed Shamakhi, Nabil Dhayhi, Shatha Matabi, Manal Maashi, Abdullah Dhaifallah Hamdi, Bander Ali, Fadhel Hazazi, Abdullah H. Alhamoud
DOI: 10.12659/AJCR.949936
Am J Case Rep 2025; 26:e949936
1,419 4,284 0

14 Dec 2025 : Case report
Bruton’s Agammaglobulinemia: Case Series and Literature Review From King Fahad Central Hospital, Jizan, Saudi Arabia
Ahmed Shamakhi, Nabil Dhayhi, Shatha Matabi, Manal Maashi, Abdullah Dhaifallah Hamdi, Bander Ali, Fadhel Hazazi, Abdullah H. Alhamoud
DOI: 10.12659/AJCR.949936
Am J Case Rep 2025; 26:e949936
1419 4284 0

12 Dec 2025 : Case report
Unpredictable Evolution of Pilocytic Astrocytoma in Adults: A Case Series and Diagnostic Challenges
Anamaria Sincu, Cristian-Ionut Orasanu
, Raluca Ioana Voda
, Madalina Bosoteanu
, Manuela Enciu
, Sorin Vamesu
, Sinziana Andra Ghitoi, Mariana Deacu
DOI: 10.12659/AJCR.947774
Am J Case Rep 2025; 26:e947774
1,225 5,913 0

12 Dec 2025 : Case report
Unpredictable Evolution of Pilocytic Astrocytoma in Adults: A Case Series and Diagnostic Challenges
Anamaria Sincu, Cristian-Ionut Orasanu
, Raluca Ioana Voda
, Madalina Bosoteanu
, Manuela Enciu
, Sorin Vamesu
, Sinziana Andra Ghitoi, Mariana Deacu
DOI: 10.12659/AJCR.947774
Am J Case Rep 2025; 26:e947774
1225 5913 0

11 Dec 2025 : Case report
A 60-Year-Old Man with an Incidental Finding of an Asymptomatic Aneurysm of the Right Gastroepiploic Artery Managed by Laparoscopic Resection
Maksymilian Baryła
, Paweł Kazimierz Ziemiański
DOI: 10.12659/AJCR.948020
Am J Case Rep 2025; 26:e948020
936 1,498 0

11 Dec 2025 : Case report
A 60-Year-Old Man with an Incidental Finding of an Asymptomatic Aneurysm of the Right Gastroepiploic Artery Managed by Laparoscopic Resection
Maksymilian Baryła
, Paweł Kazimierz Ziemiański
DOI: 10.12659/AJCR.948020
Am J Case Rep 2025; 26:e948020
936 1498 0

10 Dec 2025 : Case report
Isolated Transient Neonatal Ascites in a Preterm Infant Born to a Mother with Mirror Syndrome: A Case Report
Mo’ath Abu Hamdeh, Rasmea Mohammad Asad, Zeidan Abdalsalam, Mohammad Maraqah, Lema Saleh Khaled Jaber, Mai M.R. Rostom, Majed Methqal Abu Jaish
DOI: 10.12659/AJCR.949587
Am J Case Rep 2025; 26:e949587
1,197 2,927 0

10 Dec 2025 : Case report
Isolated Transient Neonatal Ascites in a Preterm Infant Born to a Mother with Mirror Syndrome: A Case Report
Mo’ath Abu Hamdeh, Rasmea Mohammad Asad, Zeidan Abdalsalam, Mohammad Maraqah, Lema Saleh Khaled Jaber, Mai M.R. Rostom, Majed Methqal Abu Jaish
DOI: 10.12659/AJCR.949587
Am J Case Rep 2025; 26:e949587
1197 2927 0

09 Dec 2025 : Case report
A Rare Case of Emphysematous Pyelonephritis Following Retrograde Intrarenal Surgery in an Elderly Man
Weiyong Zhong
, Feihong Xu
, Shujiang Ye, Yu Liu, Wei Zhao, Zhenquan Lu, Lin Xiong, Xiang Xu
DOI: 10.12659/AJCR.949018
Am J Case Rep 2025; 26:e949018
949 1,825 0

09 Dec 2025 : Case report
A Rare Case of Emphysematous Pyelonephritis Following Retrograde Intrarenal Surgery in an Elderly Man
Weiyong Zhong
, Feihong Xu
, Shujiang Ye, Yu Liu, Wei Zhao, Zhenquan Lu, Lin Xiong, Xiang Xu
DOI: 10.12659/AJCR.949018
Am J Case Rep 2025; 26:e949018
949 1825 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.954405
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953611
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Am J Case Rep In Press; DOI: 10.12659/AJCR.954016
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Am J Case Rep In Press; DOI: 10.12659/AJCR.954891
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