Challenging differential diagnosis

01 Dec 2025 : Case report
Late-Onset Mesh Infection 10 Years After Right Inguinal Hernia Repair: A Case Report
Ryoichi Shimizu
, Masahito Uji, Hideo Matsubara, Yasutomo Miura, Yudai Aoki, Takahiro Maehata, Kazumasa Matsuoka, Yasuji Mokuno
DOI: 10.12659/AJCR.949941
Am J Case Rep 2025; 26:e949941
966 4,706 0

01 Dec 2025 : Case report
Late-Onset Mesh Infection 10 Years After Right Inguinal Hernia Repair: A Case Report
Ryoichi Shimizu
, Masahito Uji, Hideo Matsubara, Yasutomo Miura, Yudai Aoki, Takahiro Maehata, Kazumasa Matsuoka, Yasuji Mokuno
DOI: 10.12659/AJCR.949941
Am J Case Rep 2025; 26:e949941
966 4706 0

30 Nov 2025 : Case report
Improvement of Renal Function in Atrial Fibrillation Patients via Catheter Ablation and Left Atrial Appendage Closure: A Case Report
Jiaying Chen, Caiyun Li, Yuegang Wang, Hongzeng Xu
DOI: 10.12659/AJCR.949421
Am J Case Rep 2025; 26:e949421
1,095 2,695 0

30 Nov 2025 : Case report
Improvement of Renal Function in Atrial Fibrillation Patients via Catheter Ablation and Left Atrial Appendage Closure: A Case Report
Jiaying Chen, Caiyun Li, Yuegang Wang, Hongzeng Xu
DOI: 10.12659/AJCR.949421
Am J Case Rep 2025; 26:e949421
1095 2695 0

30 Nov 2025 : Case report
Afebrile HSV-2 Encephalitis with Radiographic Atypia and Minimal Systemic Inflammation: A Case Report
Shunsuke Kondo
, Wejdan Abo Qayas, Osama Hasan, Rachel Haide N. Tacata, Matthew W. Kobylinski, Lorrance Majewski
DOI: 10.12659/AJCR.950444
Am J Case Rep 2025; 26:e950444
971 2,940 0

30 Nov 2025 : Case report
Afebrile HSV-2 Encephalitis with Radiographic Atypia and Minimal Systemic Inflammation: A Case Report
Shunsuke Kondo
, Wejdan Abo Qayas, Osama Hasan, Rachel Haide N. Tacata, Matthew W. Kobylinski, Lorrance Majewski
DOI: 10.12659/AJCR.950444
Am J Case Rep 2025; 26:e950444
971 2940 0

29 Nov 2025 : Case report
Mixed Cryoglobulinemia in the Setting of Monoclonal B-Cell Lymphocytosis and Monoclonal Gammopathy of Unknown Significance: A Case Report
Eleni Bouziani
, Luisa Ladel, Aaron James Stonestrom
DOI: 10.12659/AJCR.949597
Am J Case Rep 2025; 26:e949597
1,006 2,658 0

29 Nov 2025 : Case report
Mixed Cryoglobulinemia in the Setting of Monoclonal B-Cell Lymphocytosis and Monoclonal Gammopathy of Unknown Significance: A Case Report
Eleni Bouziani
, Luisa Ladel, Aaron James Stonestrom
DOI: 10.12659/AJCR.949597
Am J Case Rep 2025; 26:e949597
1006 2658 0

28 Nov 2025 : Case report
Persistent Primitive Hypoglossal Artery in a 55-Year-Old Woman with Recurrent Dizziness, Identified on Ultrasound and Computed Tomography Imaging
Weiwei Zhang, Zhenli Huang, Liya Wei, Yanrong Sun, Fei Sang
DOI: 10.12659/AJCR.950244
Am J Case Rep 2025; 26:e950244
708 1,356 0

28 Nov 2025 : Case report
Persistent Primitive Hypoglossal Artery in a 55-Year-Old Woman with Recurrent Dizziness, Identified on Ultrasound and Computed Tomography Imaging
Weiwei Zhang, Zhenli Huang, Liya Wei, Yanrong Sun, Fei Sang
DOI: 10.12659/AJCR.950244
Am J Case Rep 2025; 26:e950244
708 1356 0

28 Nov 2025 : Case report
Unexpected Schistosomiasis Diagnosed After Appendectomy in a Migrant Child
Isshak Mrabet-Deraoui
, Lorenzo Monforte
, Slobodan Prica
, Yvonne Schmiedel
DOI: 10.12659/AJCR.950906
Am J Case Rep 2025; 26:e950906
927 1,773 0

28 Nov 2025 : Case report
Unexpected Schistosomiasis Diagnosed After Appendectomy in a Migrant Child
Isshak Mrabet-Deraoui
, Lorenzo Monforte
, Slobodan Prica
, Yvonne Schmiedel
DOI: 10.12659/AJCR.950906
Am J Case Rep 2025; 26:e950906
927 1773 0

27 Nov 2025 : Case report
Combining Minimally Invasive Mitral Valve Replacement with Kidney Transplantation: A Pioneering Case
Abudar Al Ganadi, Ismail Al-Shameri, Nabeel Mughallis, Naseem Al-Wsabi
DOI: 10.12659/AJCR.948800
Am J Case Rep 2025; 26:e948800
1,579 1,813 0

27 Nov 2025 : Case report
Combining Minimally Invasive Mitral Valve Replacement with Kidney Transplantation: A Pioneering Case
Abudar Al Ganadi, Ismail Al-Shameri, Nabeel Mughallis, Naseem Al-Wsabi
DOI: 10.12659/AJCR.948800
Am J Case Rep 2025; 26:e948800
1579 1813 0

27 Nov 2025 : Case report
Gastric Bipartition with Functional Duodenum Exclusion (GBp-FDE) as a Possible Surgical Conversion of Sleeve Gastrectomy in Patients with De Novo GERD and Obesity Recidivism: Preliminary Results of a Case Series
Victor Ramos Mussa Dib
, Carlos Augusto Scussel Madalosso
, Paulo Reis Rizzo Esselin De Melo
, Almino Cardoso Ramos
, Luiz Alfredo Vieira D'Almeida
, Luciano Antozzi
, José María Balibrea del Castillo
, Patrick Noel
, Manoel Passos Galvão Neto
, Sonja Chiappetta
, Fernando de Barros
, André Teixeira
, Elinton Adami Chaim
, Ricardo Zorron
, Eudes Paiva de Godoy
, Caio Gustavo Gaspar de Aquino
, Giorgio Alfredo Pedroso Baretta
, Diogo Swain Kfouri
, Hiroji Okano Júnior
, Nilton Tokio Kawahara
, Augusto Cláudio de Almeida Tinoco
, Nicholas Tavares Kruel
, Joe Joaquim Waltrick Junior, Carlos Frota Dillenburg
, Félix Antônio Insaurriaga Dos Santos
, Rafael Antoniazzi Abaid
, Carlos Eduardo Alves Da Costa
, Gabriela Trentin Scortegagna
, Geovana F. Silva
, Halit Eren Taskin
, Ricardo M. Nassar
, Laurent Abram Layani
, Daniel Oscar Caiña
, Manuel Aceves Avalos
, Jorge Bravo Lópes
, José Sergio Verboonen Sotelo
, Ramon Vilallonga Puy
, Christine Karolina Stier
, Carlos Eduardo Domene
, Paula Volpe
, Amador García Ruiz de Gordejuela
, Luis Poggi
, Antônio Torres
, Miguel Ángel Carbajo
, Italo Braghetto
, Rui Ribeiro
, Chetan Parmar
DOI: 10.12659/AJCR.950798
Am J Case Rep 2025; 26:e950798
1,263 2,450 0

27 Nov 2025 : Case report
Gastric Bipartition with Functional Duodenum Exclusion (GBp-FDE) as a Possible Surgical Conversion of Sleeve Gastrectomy in Patients with De Novo GERD and Obesity Recidivism: Preliminary Results of a Case Series
Victor Ramos Mussa Dib
, Carlos Augusto Scussel Madalosso
, Paulo Reis Rizzo Esselin De Melo
, Almino Cardoso Ramos
, Luiz Alfredo Vieira D'Almeida
, Luciano Antozzi
, José María Balibrea del Castillo
, Patrick Noel
, Manoel Passos Galvão Neto
, Sonja Chiappetta
, Fernando de Barros
, André Teixeira
, Elinton Adami Chaim
, Ricardo Zorron
, Eudes Paiva de Godoy
, Caio Gustavo Gaspar de Aquino
, Giorgio Alfredo Pedroso Baretta
, Diogo Swain Kfouri
, Hiroji Okano Júnior
, Nilton Tokio Kawahara
, Augusto Cláudio de Almeida Tinoco
, Nicholas Tavares Kruel
, Joe Joaquim Waltrick Junior, Carlos Frota Dillenburg
, Félix Antônio Insaurriaga Dos Santos
, Rafael Antoniazzi Abaid
, Carlos Eduardo Alves Da Costa
, Gabriela Trentin Scortegagna
, Geovana F. Silva
, Halit Eren Taskin
, Ricardo M. Nassar
, Laurent Abram Layani
, Daniel Oscar Caiña
, Manuel Aceves Avalos
, Jorge Bravo Lópes
, José Sergio Verboonen Sotelo
, Ramon Vilallonga Puy
, Christine Karolina Stier
, Carlos Eduardo Domene
, Paula Volpe
, Amador García Ruiz de Gordejuela
, Luis Poggi
, Antônio Torres
, Miguel Ángel Carbajo
, Italo Braghetto
, Rui Ribeiro
, Chetan Parmar
DOI: 10.12659/AJCR.950798
Am J Case Rep 2025; 26:e950798
1263 2450 0

26 Nov 2025 : Case report
Pharmacological Intervention for Refractory Biofilm Infection After Hemipelvic Replacement Surgery: Multidisciplinary Management of a Case of Giant Cell Tumor of Bone
Liling Huang, Linyu Wang
, Hao Nong, Bin Liu, Yan Li
DOI: 10.12659/AJCR.949210
Am J Case Rep 2025; 26:e949210
1,020 1,848 0

26 Nov 2025 : Case report
Pharmacological Intervention for Refractory Biofilm Infection After Hemipelvic Replacement Surgery: Multidisciplinary Management of a Case of Giant Cell Tumor of Bone
Liling Huang, Linyu Wang
, Hao Nong, Bin Liu, Yan Li
DOI: 10.12659/AJCR.949210
Am J Case Rep 2025; 26:e949210
1020 1848 0

24 Nov 2025 : Case report
Bowel Obstruction Caused by Migration of an Intra-Gastric Balloon: A Rare Case Treated Laparoscopically
ٍSaeed Abdulrahman Alghamdi
, Yara Adel Alhomaidi, Nora Nasser Alqaoud, Alya Faisal Alsharif, Ali Mohammed Alzahrani, Rami Abdulrahman Sairafi
DOI: 10.12659/AJCR.948244
Am J Case Rep 2025; 26:e948244
731 1,729 0

24 Nov 2025 : Case report
Bowel Obstruction Caused by Migration of an Intra-Gastric Balloon: A Rare Case Treated Laparoscopically
ٍSaeed Abdulrahman Alghamdi
, Yara Adel Alhomaidi, Nora Nasser Alqaoud, Alya Faisal Alsharif, Ali Mohammed Alzahrani, Rami Abdulrahman Sairafi
DOI: 10.12659/AJCR.948244
Am J Case Rep 2025; 26:e948244
731 1729 0

24 Nov 2025 : Case report
Hypophysitis Induced by Tislelizumab: A Case Report of Somnolence and Delirium with Elevated Eosinophils
Fenglin Hu, Ni Lou, Guolin Wu
DOI: 10.12659/AJCR.948143
Am J Case Rep 2025; 26:e948143
1,162 1,698 0

24 Nov 2025 : Case report
Hypophysitis Induced by Tislelizumab: A Case Report of Somnolence and Delirium with Elevated Eosinophils
Fenglin Hu, Ni Lou, Guolin Wu
DOI: 10.12659/AJCR.948143
Am J Case Rep 2025; 26:e948143
1162 1698 0

23 Nov 2025 : Case report
Idiopathic Intracranial Hypertension as the Initial Manifestation of Systemic Lupus Erythematosus: A Case Report and Literature Review
Abdulaziz Almalki, Asayel Abdullah Alosaimi, Abdulhameed Sarriyah
, Sarah Alqasem, Qusai Alwazna, Faisal Theeb Alqahtani
DOI: 10.12659/AJCR.950115
Am J Case Rep 2025; 26:e950115
1,174 3,075 0

23 Nov 2025 : Case report
Idiopathic Intracranial Hypertension as the Initial Manifestation of Systemic Lupus Erythematosus: A Case Report and Literature Review
Abdulaziz Almalki, Asayel Abdullah Alosaimi, Abdulhameed Sarriyah
, Sarah Alqasem, Qusai Alwazna, Faisal Theeb Alqahtani
DOI: 10.12659/AJCR.950115
Am J Case Rep 2025; 26:e950115
1174 3075 0

21 Nov 2025 : Case report
Left-Sided Perforated Appendicitis in an Elderly Man with Intestinal Malrotation: A Case Report
Jose Samaniego-Burneo
, Jordan Llerena-Velastegui
, Alberto Gordillo-Calero, Brenda Santamaria-Penafiel, Natalia Lopez-Yepez
DOI: 10.12659/AJCR.949960
Am J Case Rep 2025; 26:e949960
983 1,615 0

21 Nov 2025 : Case report
Left-Sided Perforated Appendicitis in an Elderly Man with Intestinal Malrotation: A Case Report
Jose Samaniego-Burneo
, Jordan Llerena-Velastegui
, Alberto Gordillo-Calero, Brenda Santamaria-Penafiel, Natalia Lopez-Yepez
DOI: 10.12659/AJCR.949960
Am J Case Rep 2025; 26:e949960
983 1615 0

21 Nov 2025 : Case report
Surgical Management of Symptomatic Bilateral Elastofibroma Dorsi: A Case Report and Literature Review
Hussain Alessa, Tahar Yacoubi, Muaaz Rizig, Abdulrahman Almutawa, Jawaher Alraihan, Osamah Aldakkan
, Ali Mohammed Alghamdi, Hussain Abbas Alabdrabalnabi, Afnan Alshayeb, Wael Abdelgawad
DOI: 10.12659/AJCR.950796
Am J Case Rep 2025; 26:e950796
811 3,602 0

21 Nov 2025 : Case report
Surgical Management of Symptomatic Bilateral Elastofibroma Dorsi: A Case Report and Literature Review
Hussain Alessa, Tahar Yacoubi, Muaaz Rizig, Abdulrahman Almutawa, Jawaher Alraihan, Osamah Aldakkan
, Ali Mohammed Alghamdi, Hussain Abbas Alabdrabalnabi, Afnan Alshayeb, Wael Abdelgawad
DOI: 10.12659/AJCR.950796
Am J Case Rep 2025; 26:e950796
811 3602 0

20 Nov 2025 : Case report
Ocular Involvement in Post-Transplantation Lymphoproliferative Disorder: A Rare Case with Rituximab Hypersensitivity
Jing-yi Liu
, Wan-Ting Zhang, Kang Wang, Ying Liu, Lin Wei, Wei Qu, Zhi-Gui Zeng, Zhi-Jun Zhu, Li-Ying Sun
DOI: 10.12659/AJCR.949884
Am J Case Rep 2025; 26:e949884
1,035 1,721 0

20 Nov 2025 : Case report
Ocular Involvement in Post-Transplantation Lymphoproliferative Disorder: A Rare Case with Rituximab Hypersensitivity
Jing-yi Liu
, Wan-Ting Zhang, Kang Wang, Ying Liu, Lin Wei, Wei Qu, Zhi-Gui Zeng, Zhi-Jun Zhu, Li-Ying Sun
DOI: 10.12659/AJCR.949884
Am J Case Rep 2025; 26:e949884
1035 1721 0

19 Nov 2025 : Case report
Recombinant Factor VIIa Prophylaxis in 2 Brothers with Bernard-Soulier Syndrome
Eman Almatar, Sondus Alsharidah
, Omnia A. Hashem
DOI: 10.12659/AJCR.949654
Am J Case Rep 2025; 26:e949654
675 1,815 0

19 Nov 2025 : Case report
Recombinant Factor VIIa Prophylaxis in 2 Brothers with Bernard-Soulier Syndrome
Eman Almatar, Sondus Alsharidah
, Omnia A. Hashem
DOI: 10.12659/AJCR.949654
Am J Case Rep 2025; 26:e949654
675 1815 0

19 Nov 2025 : Case report
Multifocal Mesenteric Desmoid-Type Fibromatosis After Liver Transplantation: A Case Report
Ning Zhang, Yuqing Du, Meng Wang, Ruifang Xu, Li Li, Ying Feng, Zhanxiong Yi, Enhui He
DOI: 10.12659/AJCR.950134
Am J Case Rep 2025; 26:e950134
782 1,521 0

19 Nov 2025 : Case report
Multifocal Mesenteric Desmoid-Type Fibromatosis After Liver Transplantation: A Case Report
Ning Zhang, Yuqing Du, Meng Wang, Ruifang Xu, Li Li, Ying Feng, Zhanxiong Yi, Enhui He
DOI: 10.12659/AJCR.950134
Am J Case Rep 2025; 26:e950134
782 1521 0

18 Nov 2025 : Case report
Exploring Maralixibat for Treatment-Resistant Pruritus in Intrahepatic Cholestasis of Pregnancy and Primary Biliary Cholangitis: A Case Report
Lara Alexandra Bersuch
, Andrea De Gottardi
DOI: 10.12659/AJCR.949019
Am J Case Rep 2025; 26:e949019
1,273 3,098 0

18 Nov 2025 : Case report
Exploring Maralixibat for Treatment-Resistant Pruritus in Intrahepatic Cholestasis of Pregnancy and Primary Biliary Cholangitis: A Case Report
Lara Alexandra Bersuch
, Andrea De Gottardi
DOI: 10.12659/AJCR.949019
Am J Case Rep 2025; 26:e949019
1273 3098 0

18 Nov 2025 : Case report
Primary Cutaneous Cribriform Tumor with Clinical and Histological Diagnostic Challenges: Case Report and Literature Review of a Rare Skin Neoplasm
Wassim Hamadeh
, Elie Berbery
, Mohammad H. Abbas, Racil Allaw, Bassam F. Matar
DOI: 10.12659/AJCR.950487
Am J Case Rep 2025; 26:e950487
867 1,664 0

18 Nov 2025 : Case report
Primary Cutaneous Cribriform Tumor with Clinical and Histological Diagnostic Challenges: Case Report and Literature Review of a Rare Skin Neoplasm
Wassim Hamadeh
, Elie Berbery
, Mohammad H. Abbas, Racil Allaw, Bassam F. Matar
DOI: 10.12659/AJCR.950487
Am J Case Rep 2025; 26:e950487
867 1664 0

17 Nov 2025 : Case report
Concurrent Mature and Immature Teratomas in Contralateral Ovaries in a 30-Year-Old Woman: A Case Report
Izabela Targosińska
, Dorota Lewkowicz
, Barbara Marzec-Kotarska
DOI: 10.12659/AJCR.949404
Am J Case Rep 2025; 26:e949404
813 5,135 0

17 Nov 2025 : Case report
Concurrent Mature and Immature Teratomas in Contralateral Ovaries in a 30-Year-Old Woman: A Case Report
Izabela Targosińska
, Dorota Lewkowicz
, Barbara Marzec-Kotarska
DOI: 10.12659/AJCR.949404
Am J Case Rep 2025; 26:e949404
813 5135 0

17 Nov 2025 : Case report
Sclerosing Cholangitis and Multiple Liver Abscesses in a Patient with Thymoma, Myasthenia Gravis, and Immune Deficiency (Good’s Syndrome)
Shaul Yaari, Joshua Stokar
, Yehonatan Bar Moshe, Nurith Hiller, Elena Zuckerman, Samuel N. Heyman
DOI: 10.12659/AJCR.948856
Am J Case Rep 2025; 26:e948856
944 1,550 0

17 Nov 2025 : Case report
Sclerosing Cholangitis and Multiple Liver Abscesses in a Patient with Thymoma, Myasthenia Gravis, and Immune Deficiency (Good’s Syndrome)
Shaul Yaari, Joshua Stokar
, Yehonatan Bar Moshe, Nurith Hiller, Elena Zuckerman, Samuel N. Heyman
DOI: 10.12659/AJCR.948856
Am J Case Rep 2025; 26:e948856
944 1550 0

14 Nov 2025 : Case report
Daratumumab-Based Regimen Significantly Induced Remission of Crystalline Light Chain Proximal Tubulopathy: A Case Report
Xia Zou, Kun Wang, Rui Zeng
DOI: 10.12659/AJCR.948890
Am J Case Rep 2025; 26:e948890
1,069 2,516 0

14 Nov 2025 : Case report
Daratumumab-Based Regimen Significantly Induced Remission of Crystalline Light Chain Proximal Tubulopathy: A Case Report
Xia Zou, Kun Wang, Rui Zeng
DOI: 10.12659/AJCR.948890
Am J Case Rep 2025; 26:e948890
1069 2516 0

14 Nov 2025 : Case report
Reverse Takotsubo Cardiomyopathy After Treatment of Asymptomatic Bradycardia Prior to Anesthesia Induction in a Young Woman Undergoing Elective Rhinoplasty: A Case Report
Samantha Henry, Kelly Rothbart, Amit Prasad
DOI: 10.12659/AJCR.950112
Am J Case Rep 2025; 26:e950112
1,224 1,888 0

14 Nov 2025 : Case report
Reverse Takotsubo Cardiomyopathy After Treatment of Asymptomatic Bradycardia Prior to Anesthesia Induction in a Young Woman Undergoing Elective Rhinoplasty: A Case Report
Samantha Henry, Kelly Rothbart, Amit Prasad
DOI: 10.12659/AJCR.950112
Am J Case Rep 2025; 26:e950112
1224 1888 0

13 Nov 2025 : Case report
Eosinophilic Gastroenteritis Accompanied with Partial Midgut Malrotation in an Adult: A Case Report
Xiaotong Cui, Changlei Li, Yukun Liu, Xue Zhong, Kunpeng Wei, Chao Wu, Zusen Wang
DOI: 10.12659/AJCR.950370
Am J Case Rep 2025; 26:e950370
864 1,295 0

13 Nov 2025 : Case report
Eosinophilic Gastroenteritis Accompanied with Partial Midgut Malrotation in an Adult: A Case Report
Xiaotong Cui, Changlei Li, Yukun Liu, Xue Zhong, Kunpeng Wei, Chao Wu, Zusen Wang
DOI: 10.12659/AJCR.950370
Am J Case Rep 2025; 26:e950370
864 1295 0

13 Nov 2025 : Case report
Use of Bonebridge Implant in a Child with Congenital Cholesteatoma: A Case Report
Katarzyna B. Cywka
, Emilia A. Czaplicka
, Piotr H. Skarżyński
DOI: 10.12659/AJCR.949341
Am J Case Rep 2025; 26:e949341
908 1,665 0

13 Nov 2025 : Case report
Use of Bonebridge Implant in a Child with Congenital Cholesteatoma: A Case Report
Katarzyna B. Cywka
, Emilia A. Czaplicka
, Piotr H. Skarżyński
DOI: 10.12659/AJCR.949341
Am J Case Rep 2025; 26:e949341
908 1665 0
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Am J Case Rep In Press; DOI: 10.12659/AJCR.954216
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Am J Case Rep In Press; DOI: 10.12659/AJCR.954932
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Am J Case Rep In Press; DOI: 10.12659/AJCR.954146
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Am J Case Rep In Press; DOI: 10.12659/AJCR.953555
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