Challenging differential diagnosis
19 Aug 2025 : Case report 
Central Pontine Myelinolysis in a Patient with Alcohol Use Disorder without Hyponatremia: A Case Report
Anastasia Demina, Simon Amaral, Benjamin Petit 
, Vincent Meille, Yannick Béjot , Benoit Trojak
DOI: 10.12659/AJCR.947709
Am J Case Rep 2025; 26:e947709
584 1,416 0
19 Aug 2025 : Case report
Central Pontine Myelinolysis in a Patient with Alcohol Use Disorder without Hyponatremia: A Case Report
Anastasia Demina, Simon Amaral, Benjamin Petit , Vincent Meille, Yannick Béjot , Benoit Trojak
DOI: 10.12659/AJCR.947709
Am J Case Rep 2025; 26:e947709
584 1416 0
14 Aug 2025 : Case report 
A 66-Year-Old Man with Intrapleural Leakage of Parenteral Nutrition Fluid Due to a Malpositioned Central Venous Catheter
Jakob Van Herck, Wouter Snoeck, Marc Vanhoof, Helena Van Damme, Lynn Decoster
DOI: 10.12659/AJCR.948181
Am J Case Rep 2025; 26:e948181
1,244 958 0
14 Aug 2025 : Case report
A 66-Year-Old Man with Intrapleural Leakage of Parenteral Nutrition Fluid Due to a Malpositioned Central Venous Catheter
Jakob Van Herck, Wouter Snoeck, Marc Vanhoof, Helena Van Damme, Lynn Decoster
DOI: 10.12659/AJCR.948181
Am J Case Rep 2025; 26:e948181
1244 958 0
18 Aug 2025 : Case report 
Crucial Role of Early Detection in Managing Heart Failure in Kearns-Sayre Syndrome: A Case Report
Dominik Krupka , Katarzyna Rakoczy , Adam Chełmoński , Michał Zakliczyński , Roman Przybylski , Mateusz Sokolski
DOI: 10.12659/AJCR.947439
Am J Case Rep 2025; 26:e947439
611 938 0
18 Aug 2025 : Case report
Crucial Role of Early Detection in Managing Heart Failure in Kearns-Sayre Syndrome: A Case Report
Dominik Krupka , Katarzyna Rakoczy , Adam Chełmoński , Michał Zakliczyński , Roman Przybylski , Mateusz Sokolski
DOI: 10.12659/AJCR.947439
Am J Case Rep 2025; 26:e947439
611 938 0
20 Aug 2025 : Case report 
Diagnosis and Management of Large Extraosseous Myxoid Chondrosarcoma of the Buttocks: A Case Report
Qing Hong Lai, Chun Mei Zhong, Xue Qi Sun, Hua Ye, Yan Zhang, Jia Jing Tu, Jun Feng Sun
DOI: 10.12659/AJCR.947135
Am J Case Rep 2025; 26:e947135
372 1,074 0
20 Aug 2025 : Case report
Diagnosis and Management of Large Extraosseous Myxoid Chondrosarcoma of the Buttocks: A Case Report
Qing Hong Lai, Chun Mei Zhong, Xue Qi Sun, Hua Ye, Yan Zhang, Jia Jing Tu, Jun Feng Sun
DOI: 10.12659/AJCR.947135
Am J Case Rep 2025; 26:e947135
372 1074 0
18 Aug 2025 : Case report
Balancing Empirical Treatment and Comprehensive Evaluation in a Case of Suspected Rickettsial Infection: A Diagnostic Dilemma in Recurrent Fever
Jing Ding, Ju Tian, Xingqi Chen
DOI: 10.12659/AJCR.948614
Am J Case Rep 2025; 26:e948614
449 752 0
18 Aug 2025 : Case report
Balancing Empirical Treatment and Comprehensive Evaluation in a Case of Suspected Rickettsial Infection: A Diagnostic Dilemma in Recurrent Fever
Jing Ding, Ju Tian, Xingqi Chen
DOI: 10.12659/AJCR.948614
Am J Case Rep 2025; 26:e948614
449 752 0
15 Aug 2025 : Case report
HELLP Syndrome with Hepatic and Thoracic Complications: Insights From a Case of Spontaneous Liver Rupture
Sanqiang Niu, Kangjun Yu, Yayun Cheng, Ning Liu
DOI: 10.12659/AJCR.949380
Am J Case Rep 2025; 26:e949380
451 1,365 0
15 Aug 2025 : Case report
HELLP Syndrome with Hepatic and Thoracic Complications: Insights From a Case of Spontaneous Liver Rupture
Sanqiang Niu, Kangjun Yu, Yayun Cheng, Ning Liu
DOI: 10.12659/AJCR.949380
Am J Case Rep 2025; 26:e949380
451 1365 0
10 Aug 2025 : Case report 
Disseminated Blastomycosis: A Case of Multisite Infection in an Immunocompetent Patient
Vishnu Teja Kommineni , Joshua J. Jagodzinski, Emilia Elena Petcu, Celestine Odenigbo, Rathnamitreyee Vegunta , Igor Dumic
DOI: 10.12659/AJCR.949647
Am J Case Rep 2025; 26:e949647
883 926 0
10 Aug 2025 : Case report
Disseminated Blastomycosis: A Case of Multisite Infection in an Immunocompetent Patient
Vishnu Teja Kommineni , Joshua J. Jagodzinski, Emilia Elena Petcu, Celestine Odenigbo, Rathnamitreyee Vegunta , Igor Dumic
DOI: 10.12659/AJCR.949647
Am J Case Rep 2025; 26:e949647
883 926 0
11 Aug 2025 : Case report 
Complex Interplay Between Sweet Syndrome and Therapy-Related Myelodysplastic Syndrome After B-Cell Lymphoma Treatment: A Case Report
Hiroto Yamashita, Shuhei Kurosawa, Yukari Hamamura, Yoko Tateishi, Hiroyuki Hayashi, Takeshi Kambara, Tomonori Nakazato
DOI: 10.12659/AJCR.949165
Am J Case Rep 2025; 26:e949165
1,243 1,108 0
11 Aug 2025 : Case report
Complex Interplay Between Sweet Syndrome and Therapy-Related Myelodysplastic Syndrome After B-Cell Lymphoma Treatment: A Case Report
Hiroto Yamashita, Shuhei Kurosawa, Yukari Hamamura, Yoko Tateishi, Hiroyuki Hayashi, Takeshi Kambara, Tomonori Nakazato
DOI: 10.12659/AJCR.949165
Am J Case Rep 2025; 26:e949165
1243 1108 0
09 Aug 2025 : Case report
Primary Adrenal Lymphoma Diagnosed by Endoscopic Ultrasound Fine-Needle Aspiration Biopsy: A Case Report
Yuzheng Zhao, Ning Chen
DOI: 10.12659/AJCR.948833
Am J Case Rep 2025; 26:e948833
721 817 0
09 Aug 2025 : Case report
Primary Adrenal Lymphoma Diagnosed by Endoscopic Ultrasound Fine-Needle Aspiration Biopsy: A Case Report
Yuzheng Zhao, Ning Chen
DOI: 10.12659/AJCR.948833
Am J Case Rep 2025; 26:e948833
721 817 0
06 Aug 2025 : Case report
Unveiling Maternal Germline Mosaicism in X-Linked Alport Syndrome by Advanced Genetic Testing
Yuting Shen, Caihong Liu, Wei Wei, Yongxiu Huang , Qian Zhu, Yuliang Zhao
DOI: 10.12659/AJCR.947287
Am J Case Rep 2025; 26:e947287
781 800 0
06 Aug 2025 : Case report
Unveiling Maternal Germline Mosaicism in X-Linked Alport Syndrome by Advanced Genetic Testing
Yuting Shen, Caihong Liu, Wei Wei, Yongxiu Huang , Qian Zhu, Yuliang Zhao
DOI: 10.12659/AJCR.947287
Am J Case Rep 2025; 26:e947287
781 800 0
05 Aug 2025 : Case report
Recurrent Severe Hyponatremia Following Polyethylene Glycol Electrolyte Lavage Solution with Ascorbic Acid in a Patient with Undiagnosed Syndrome of Inappropriate Antidiuretic Hormone Secretion
Koichi Soga , Yuto Suzuki, Fuki Hayakawa, Takeshi Fujiwara, Takahiro Ota, Ikuhiro Kobori , Masaya Tamano
DOI: 10.12659/AJCR.948355
Am J Case Rep 2025; 26:e948355
985 1,329 0
05 Aug 2025 : Case report
Recurrent Severe Hyponatremia Following Polyethylene Glycol Electrolyte Lavage Solution with Ascorbic Acid in a Patient with Undiagnosed Syndrome of Inappropriate Antidiuretic Hormone Secretion
Koichi Soga , Yuto Suzuki, Fuki Hayakawa, Takeshi Fujiwara, Takahiro Ota, Ikuhiro Kobori , Masaya Tamano
DOI: 10.12659/AJCR.948355
Am J Case Rep 2025; 26:e948355
985 1329 0
04 Aug 2025 : Case report 
Visceral Arterial Thrombosis Linked to Long-Term Oral Contraceptives and Smoking: A Case Report
Laura Leci Tahiri, Valdete Haxhibeqiri
DOI: 10.12659/AJCR.948398
Am J Case Rep 2025; 26:e948398
727 1,192 0
04 Aug 2025 : Case report
Visceral Arterial Thrombosis Linked to Long-Term Oral Contraceptives and Smoking: A Case Report
Laura Leci Tahiri, Valdete Haxhibeqiri
DOI: 10.12659/AJCR.948398
Am J Case Rep 2025; 26:e948398
727 1192 0
03 Aug 2025 : Case report 
Personalized In Vitro Fertilization Protocols in Premature Ovarian Insufficiency and Male-Factor Infertility: A Case Series
Agus Heriyanto, Dian Tjahyadi, Anita Rachmawati, Ayu Insafi Mulyantari
DOI: 10.12659/AJCR.947396
Am J Case Rep 2025; 26:e947396
1,086 1,459 0
03 Aug 2025 : Case report
Personalized In Vitro Fertilization Protocols in Premature Ovarian Insufficiency and Male-Factor Infertility: A Case Series
Agus Heriyanto, Dian Tjahyadi, Anita Rachmawati, Ayu Insafi Mulyantari
DOI: 10.12659/AJCR.947396
Am J Case Rep 2025; 26:e947396
1086 1459 0
02 Aug 2025 : Case report 
Advanced Strategies for Managing Pleuroperitoneal Communication in Peritoneal Dialysis Patients: Report of Two Cases
Paolo Ria , Luca Luongo, Vilma Martella, Anna Zito , Silvia Matino, Silvia Barbarini, Paolo Protopapa, Davide Gianfreda , Antonio De Pascalis, Luigi Gaetano Andriolo
DOI: 10.12659/AJCR.947860
Am J Case Rep 2025; 26:e947860
998 1,205 0
02 Aug 2025 : Case report
Advanced Strategies for Managing Pleuroperitoneal Communication in Peritoneal Dialysis Patients: Report of Two Cases
Paolo Ria , Luca Luongo, Vilma Martella, Anna Zito , Silvia Matino, Silvia Barbarini, Paolo Protopapa, Davide Gianfreda , Antonio De Pascalis, Luigi Gaetano Andriolo
DOI: 10.12659/AJCR.947860
Am J Case Rep 2025; 26:e947860
998 1205 0
01 Aug 2025 : Case report 
Immunoadsorption as a Rescue Therapy for Very High Anti-B Titer in ABO-Incompatible Kidney Transplantation
Chanyanuch Rakpithayanon, Nattapakorn Mai-on, Sirihatai Konwai , Thunyatorn Wuttiputhanun, Natavudh Townamchai , Methee Sutherasan, Julin Opanuraks, Yingyos Avihingsanon , Suwasin Udomkarnjananun
DOI: 10.12659/AJCR.948529
Am J Case Rep 2025; 26:e948529
684 874 0
01 Aug 2025 : Case report
Immunoadsorption as a Rescue Therapy for Very High Anti-B Titer in ABO-Incompatible Kidney Transplantation
Chanyanuch Rakpithayanon, Nattapakorn Mai-on, Sirihatai Konwai , Thunyatorn Wuttiputhanun, Natavudh Townamchai , Methee Sutherasan, Julin Opanuraks, Yingyos Avihingsanon , Suwasin Udomkarnjananun
DOI: 10.12659/AJCR.948529
Am J Case Rep 2025; 26:e948529
684 874 0
27 Jul 2025 : Case report
One Patient with 3 Antibody-Confirmed Neurological Autoimmune Syndromes: A Case Report and Review of the Literature
Lauren A. Nguyen, Frishan Rocel O. Paulo, Jordan J. Petersen, J. Douglas Miles
DOI: 10.12659/AJCR.948329
Am J Case Rep 2025; 26:e948329
1,038 1,505 0
27 Jul 2025 : Case report
One Patient with 3 Antibody-Confirmed Neurological Autoimmune Syndromes: A Case Report and Review of the Literature
Lauren A. Nguyen, Frishan Rocel O. Paulo, Jordan J. Petersen, J. Douglas Miles
DOI: 10.12659/AJCR.948329
Am J Case Rep 2025; 26:e948329
1038 1505 0
30 Jul 2025 : Case report
Successful Management of Severe Refractory ARDS in Hemophagocytic Lymphohistiocytosis with VV-ECMO: A Case Report and Analysis
Mengqi Guan, Yan Qian, Zihua Tang, Yingya Cao, Xiaogan Jiang, Weihua Lu, Qiancheng Xu
DOI: 10.12659/AJCR.949154
Am J Case Rep 2025; 26:e949154
935 1,403 0
30 Jul 2025 : Case report
Successful Management of Severe Refractory ARDS in Hemophagocytic Lymphohistiocytosis with VV-ECMO: A Case Report and Analysis
Mengqi Guan, Yan Qian, Zihua Tang, Yingya Cao, Xiaogan Jiang, Weihua Lu, Qiancheng Xu
DOI: 10.12659/AJCR.949154
Am J Case Rep 2025; 26:e949154
935 1403 0
25 Jul 2025 : Case report
Distinguishing Wernicke Encephalopathy from Artery of Percheron Infarction in a 43-Year-Old Man: A Case Report
Syed Raza, Salma Mohamed, Nazia Naz S. Khan
DOI: 10.12659/AJCR.948636
Am J Case Rep 2025; 26:e948636
773 922 0
25 Jul 2025 : Case report
Distinguishing Wernicke Encephalopathy from Artery of Percheron Infarction in a 43-Year-Old Man: A Case Report
Syed Raza, Salma Mohamed, Nazia Naz S. Khan
DOI: 10.12659/AJCR.948636
Am J Case Rep 2025; 26:e948636
773 922 0
24 Jul 2025 : Case report
Ectopic Adrenocortical Adenoma Causing Malignant Hypertension and Hypokalemia
Xiaoyong Hu , Djandan Tadum Arthur Vithran , Zhaoying Yang, Hongjian Li
DOI: 10.12659/AJCR.948022
Am J Case Rep 2025; 26:e948022
904 1,670 0
24 Jul 2025 : Case report
Ectopic Adrenocortical Adenoma Causing Malignant Hypertension and Hypokalemia
Xiaoyong Hu , Djandan Tadum Arthur Vithran , Zhaoying Yang, Hongjian Li
DOI: 10.12659/AJCR.948022
Am J Case Rep 2025; 26:e948022
904 1670 0
22 Jul 2025 : Case report
Leukemoid Reactions in Pancreatic Cancer: A Case Series
Teng Huang, Tangchun Liu, Siqi Liu, Zhengfei Yang
DOI: 10.12659/AJCR.948491
Am J Case Rep 2025; 26:e948491
1,053 2,363 0
22 Jul 2025 : Case report
Leukemoid Reactions in Pancreatic Cancer: A Case Series
Teng Huang, Tangchun Liu, Siqi Liu, Zhengfei Yang
DOI: 10.12659/AJCR.948491
Am J Case Rep 2025; 26:e948491
1053 2363 0
21 Jul 2025 : Case report
Diagnosing Disseminated Peritoneal Leiomyomatosis: Malignancy-Like Presentation in a 59-Year-Old Woman
Changchao Xiao, Haixing Ju, Jun Cao
DOI: 10.12659/AJCR.947246
Am J Case Rep 2025; 26:e947246
763 1,229 0
21 Jul 2025 : Case report
Diagnosing Disseminated Peritoneal Leiomyomatosis: Malignancy-Like Presentation in a 59-Year-Old Woman
Changchao Xiao, Haixing Ju, Jun Cao
DOI: 10.12659/AJCR.947246
Am J Case Rep 2025; 26:e947246
763 1229 0
19 Jul 2025 : Case report
Adult Hemophagocytic Lymphohistiocytosis (HLH) with Neurological Involvement: Diagnostic Complexities – A Case Report and Literature Review
Michał J. Sekuła , Anna Jamroz-Wiśniewska , Urszula Chyrchel-Paszkiewicz , Aleksandra Pietruczuk , Aleksandra Dembowska , Maciej Dubaj , Karol Bigosiński , Konrad Rejdak
DOI: 10.12659/AJCR.947694
Am J Case Rep 2025; 26:e947694
1,357 1,719 0
19 Jul 2025 : Case report
Adult Hemophagocytic Lymphohistiocytosis (HLH) with Neurological Involvement: Diagnostic Complexities – A Case Report and Literature Review
Michał J. Sekuła , Anna Jamroz-Wiśniewska , Urszula Chyrchel-Paszkiewicz , Aleksandra Pietruczuk , Aleksandra Dembowska , Maciej Dubaj , Karol Bigosiński , Konrad Rejdak
DOI: 10.12659/AJCR.947694
Am J Case Rep 2025; 26:e947694
1357 1719 0
17 Jul 2025 : Case report
Recognizing Exocrine Pancreatic Insufficiency in Patients with Diabetes: A Case Study
Victoria Kusztos , Mariya Pogorelova
DOI: 10.12659/AJCR.948283
Am J Case Rep 2025; 26:e948283
798 1,260 0
17 Jul 2025 : Case report
Recognizing Exocrine Pancreatic Insufficiency in Patients with Diabetes: A Case Study
Victoria Kusztos , Mariya Pogorelova
DOI: 10.12659/AJCR.948283
Am J Case Rep 2025; 26:e948283
798 1260 0
16 Jul 2025 : Case report 
Endovascular Embolization in Acquired Hemophilia A: A Case Study Highlighting Diagnostic and Therapeutic Strategies
Michail Makris, Stavroula Bountola, Vasileios Patriarcheas, Anastasia Adamou , Panagiota Tsiatsiou , Vasileios Perifanis , Christos Savopoulos, Georgia Kaiafa
DOI: 10.12659/AJCR.948268
Am J Case Rep 2025; 26:e948268
877 1,442 0
16 Jul 2025 : Case report
Endovascular Embolization in Acquired Hemophilia A: A Case Study Highlighting Diagnostic and Therapeutic Strategies
Michail Makris, Stavroula Bountola, Vasileios Patriarcheas, Anastasia Adamou , Panagiota Tsiatsiou , Vasileios Perifanis , Christos Savopoulos, Georgia Kaiafa
DOI: 10.12659/AJCR.948268
Am J Case Rep 2025; 26:e948268
877 1442 0
13 Jul 2025 : Case report 
Adult Acute Appendicitis Complicated by Intestinal Malrotation: A Case Analysis
Daniel Krstic , Dimitrios Chatziisaak , Strahinja Konstantinović , Luca Benigno, Christopher Soll, Magdalena Biraima
DOI: 10.12659/AJCR.949194
Am J Case Rep 2025; 26:e949194
736 1,530 0
13 Jul 2025 : Case report
Adult Acute Appendicitis Complicated by Intestinal Malrotation: A Case Analysis
Daniel Krstic , Dimitrios Chatziisaak , Strahinja Konstantinović , Luca Benigno, Christopher Soll, Magdalena Biraima
DOI: 10.12659/AJCR.949194
Am J Case Rep 2025; 26:e949194
736 1530 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.949976
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.950290
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.950607
Case report 
Am J Case Rep In Press; DOI: 10.12659/AJCR.950985
Most Viewed Current Articles
07 Dec 2021 : Case report
17,691,734
DOI :10.12659/AJCR.934347
Am J Case Rep 2021; 22:e934347
06 Dec 2021 : Case report 
164,491
DOI :10.12659/AJCR.934406
Am J Case Rep 2021; 22:e934406
21 Jun 2024 : Case report
113,090
DOI :10.12659/AJCR.944371
Am J Case Rep 2024; 25:e944371
07 Mar 2024 : Case report
59,175
DOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133