Challenging differential diagnosis

28 Mar 2026 : Case report
Hormone Receptor–Positive Encapsulated Papillary Carcinoma of the Breast With High-Grade Cytological Features: A Case Report With Invasive Heterogeneity
Yao Liu, Akihiro Shioya
, Yusuke Haba, Masafumi Inokuchi, Sohsuke Yamada
DOI: 10.12659/AJCR.951744
Am J Case Rep 2026; 27:e951744
473 1,159 0

28 Mar 2026 : Case report
Hormone Receptor–Positive Encapsulated Papillary Carcinoma of the Breast With High-Grade Cytological Features: A Case Report With Invasive Heterogeneity
Yao Liu, Akihiro Shioya
, Yusuke Haba, Masafumi Inokuchi, Sohsuke Yamada
DOI: 10.12659/AJCR.951744
Am J Case Rep 2026; 27:e951744
473 1159 0

27 Mar 2026 : Case report
Reverse Takotsubo Syndrome Triggered by COVID-19–Associated Cytokine Storm: Unveiling a Novel Pattern of Myocardial Dysfunction in SARS-CoV-2 Infection
Killen H. Briones-Claudett
, Killen H. Briones-Zamora
, Jaime Benites Solís
, María Antonieta Touriz Bonifaz
, Enny Berrus Zhumi
, Anahí D. Briones-Zamora
, Diana C. Briones Márquez
, Angela Germania Monserrate Romero
, Miguel Anderson Tayupanta Alban
, Hans Mautong
DOI: 10.12659/AJCR.951623
Am J Case Rep 2026; 27:e951623
671 1,236 0

27 Mar 2026 : Case report
Reverse Takotsubo Syndrome Triggered by COVID-19–Associated Cytokine Storm: Unveiling a Novel Pattern of Myocardial Dysfunction in SARS-CoV-2 Infection
Killen H. Briones-Claudett
, Killen H. Briones-Zamora
, Jaime Benites Solís
, María Antonieta Touriz Bonifaz
, Enny Berrus Zhumi
, Anahí D. Briones-Zamora
, Diana C. Briones Márquez
, Angela Germania Monserrate Romero
, Miguel Anderson Tayupanta Alban
, Hans Mautong
DOI: 10.12659/AJCR.951623
Am J Case Rep 2026; 27:e951623
671 1236 0

25 Mar 2026 : Case report
Gastric Point-of-Care Ultrasound Diagnosis of Unexpected Gastrointestinal Dysfunction During ICU Ward Rounds: A Case Report
Polyxeni Theodosopoulou
, Miguel Ángel Fernandez-Vaquero
, Ariel Duilio González-Delgado
, Marc Vives
DOI: 10.12659/AJCR.951576
Am J Case Rep 2026; 27:e951576
603 832 0

25 Mar 2026 : Case report
Gastric Point-of-Care Ultrasound Diagnosis of Unexpected Gastrointestinal Dysfunction During ICU Ward Rounds: A Case Report
Polyxeni Theodosopoulou
, Miguel Ángel Fernandez-Vaquero
, Ariel Duilio González-Delgado
, Marc Vives
DOI: 10.12659/AJCR.951576
Am J Case Rep 2026; 27:e951576
603 832 0

24 Mar 2026 : Case report
A 31-Year-Old Primigravida Woman Presenting at 18 Weeks of Gestation With Right Ovarian Torsion Successfully Managed With Laparoscopic Adnexectomy
Paolo Meloni, Sara Izzo, Terenzia Simari, Daniela Messineo
, Pierfrancesco Di Cello, Silvia Lai, Silvia Andrietti, Rodolfo Brizio, Cristina Vignale, Luciano Izzo
, Marcello Molle, Paolo Izzo
DOI: 10.12659/AJCR.951849
Am J Case Rep 2026; 27:e951849
495 791 0

24 Mar 2026 : Case report
A 31-Year-Old Primigravida Woman Presenting at 18 Weeks of Gestation With Right Ovarian Torsion Successfully Managed With Laparoscopic Adnexectomy
Paolo Meloni, Sara Izzo, Terenzia Simari, Daniela Messineo
, Pierfrancesco Di Cello, Silvia Lai, Silvia Andrietti, Rodolfo Brizio, Cristina Vignale, Luciano Izzo
, Marcello Molle, Paolo Izzo
DOI: 10.12659/AJCR.951849
Am J Case Rep 2026; 27:e951849
495 791 0

25 Mar 2026 : Case report
Adult-Onset Nesidioblastosis: A Challenging Diagnosis Revealed by Endoscopic Ultrasonography
Kristína Cmarková, Peter Uhrík, Roman Kyčina, Lenka Nosáková, Miroslav Pindura, Martin Grajciar, Michal Kalman, Peter Bánovčin, Juraj Miklušica
DOI: 10.12659/AJCR.951251
Am J Case Rep 2026; 27:e951251
567 1,173 0

25 Mar 2026 : Case report
Adult-Onset Nesidioblastosis: A Challenging Diagnosis Revealed by Endoscopic Ultrasonography
Kristína Cmarková, Peter Uhrík, Roman Kyčina, Lenka Nosáková, Miroslav Pindura, Martin Grajciar, Michal Kalman, Peter Bánovčin, Juraj Miklušica
DOI: 10.12659/AJCR.951251
Am J Case Rep 2026; 27:e951251
567 1173 0

22 Mar 2026 : Case report
Management Strategy for Anaphylaxis in a Patient With Suspected or Confirmed Mastocytosis: A Case Report
Krzysztof Smoluchowski
, Mateusz Szymański
, Małgorzata Maria Skiba
, Małgorzata Piasecka
DOI: 10.12659/AJCR.951085
Am J Case Rep 2026; 27:e951085
644 1,080 0

22 Mar 2026 : Case report
Management Strategy for Anaphylaxis in a Patient With Suspected or Confirmed Mastocytosis: A Case Report
Krzysztof Smoluchowski
, Mateusz Szymański
, Małgorzata Maria Skiba
, Małgorzata Piasecka
DOI: 10.12659/AJCR.951085
Am J Case Rep 2026; 27:e951085
644 1080 0

23 Mar 2026 : Case report
Isolated Premature Menarche in a 17-Month-Old: A Case Report
Dewi Rani Pelitawati
, Artha Falentin Putri Susilo
, Anita Rachmawati
, Wiryawan Permadi
, Putri Nadhira Adinda Adriansyah
, Nabila Chantikarizky Hasanah
DOI: 10.12659/AJCR.947844
Am J Case Rep 2026; 27:e947844
712 2,225 0

23 Mar 2026 : Case report
Isolated Premature Menarche in a 17-Month-Old: A Case Report
Dewi Rani Pelitawati
, Artha Falentin Putri Susilo
, Anita Rachmawati
, Wiryawan Permadi
, Putri Nadhira Adinda Adriansyah
, Nabila Chantikarizky Hasanah
DOI: 10.12659/AJCR.947844
Am J Case Rep 2026; 27:e947844
712 2225 0

23 Mar 2026 : Case report
Diagnostic Value of Next-Generation Sequencing (NGS) and Microarray in Characterizing Tumor Origin: A Challenging and Educational Case
DOI: 10.12659/AJCR.951658
Am J Case Rep 2026; 27:e951658
546 775 0

23 Mar 2026 : Case report
Diagnostic Value of Next-Generation Sequencing (NGS) and Microarray in Characterizing Tumor Origin: A Challenging and Educational Case
DOI: 10.12659/AJCR.951658
Am J Case Rep 2026; 27:e951658
546 775 0

21 Mar 2026 : Case report
Robotic Surgical Repair of a Parahiatal Hernia: A Case Report
Sarah Hughes
, Harmanpreet Kakkar
DOI: 10.12659/AJCR.950925
Am J Case Rep 2026; 27:e950925
475 738 0

21 Mar 2026 : Case report
Robotic Surgical Repair of a Parahiatal Hernia: A Case Report
Sarah Hughes
, Harmanpreet Kakkar
DOI: 10.12659/AJCR.950925
Am J Case Rep 2026; 27:e950925
475 738 0

20 Mar 2026 : Case report
Nonatherosclerotic Subclavian Steal Syndrome Due to Brachiocephalic Trunk Kinking in an Elderly Woman: A Case Report
Mauro De Deus Passos, Pedro R.M. Negreiros de Almeida, Rodolfo Loureiro Borges de Souza, Arthur Barroso Vidal Vilarinho, Daniella de Sousa Mendes Moreira Alves, Luciano Moreira Alves
DOI: 10.12659/AJCR.950305
Am J Case Rep 2026; 27:e950305
582 1,325 0

20 Mar 2026 : Case report
Nonatherosclerotic Subclavian Steal Syndrome Due to Brachiocephalic Trunk Kinking in an Elderly Woman: A Case Report
Mauro De Deus Passos, Pedro R.M. Negreiros de Almeida, Rodolfo Loureiro Borges de Souza, Arthur Barroso Vidal Vilarinho, Daniella de Sousa Mendes Moreira Alves, Luciano Moreira Alves
DOI: 10.12659/AJCR.950305
Am J Case Rep 2026; 27:e950305
582 1325 0

17 Feb 2026 : Case report
Anti-MDA5 Antibody-Positive Dermatomyositis in Emirati Patients: A Case Series Highlighting Clinical Variability
Deena Ahmed, Khulood Khawaja, Afra Al Dhaheri, Abdulla Alshamsi, Amna Almheiri, Ahlam Almarzooqi, Sarah Al Qassimi, Rajaie Namas, Gehad ElGhazali
DOI: 10.12659/AJCR.951064
Am J Case Rep 2026; 27:e951064
1,053 2,642 0

17 Feb 2026 : Case report
Anti-MDA5 Antibody-Positive Dermatomyositis in Emirati Patients: A Case Series Highlighting Clinical Variability
Deena Ahmed, Khulood Khawaja, Afra Al Dhaheri, Abdulla Alshamsi, Amna Almheiri, Ahlam Almarzooqi, Sarah Al Qassimi, Rajaie Namas, Gehad ElGhazali
DOI: 10.12659/AJCR.951064
Am J Case Rep 2026; 27:e951064
1053 2642 0

19 Mar 2026 : Case report
Early Diagnosis of Nieman–Pick Disease Type C and Rapid Response of Gelastic Cataplexy to Treatment With N-Acetyl-L-Leucine: A Case Report
Kitiwan Rojnueangnit
, Sukita Puttamanee
, Sukkrawan Intarakhao, Khanittha Khusiwilai
DOI: 10.12659/AJCR.951570
Am J Case Rep 2026; 27:e951570
714 1,233 0

19 Mar 2026 : Case report
Early Diagnosis of Nieman–Pick Disease Type C and Rapid Response of Gelastic Cataplexy to Treatment With N-Acetyl-L-Leucine: A Case Report
Kitiwan Rojnueangnit
, Sukita Puttamanee
, Sukkrawan Intarakhao, Khanittha Khusiwilai
DOI: 10.12659/AJCR.951570
Am J Case Rep 2026; 27:e951570
714 1233 0

17 Mar 2026 : Case report
Linezolid-Associated Triad of Acute Pancreatitis, Lactic Acidosis, and Hypoglycemia: A Rare Case Report and Literature Review
Manar Abdullah Makin, Ahmed Hussein Subki
, Manal Ismail Bokhary
DOI: 10.12659/AJCR.950688
Am J Case Rep 2026; 27:e950688
700 1,344 0

17 Mar 2026 : Case report
Linezolid-Associated Triad of Acute Pancreatitis, Lactic Acidosis, and Hypoglycemia: A Rare Case Report and Literature Review
Manar Abdullah Makin, Ahmed Hussein Subki
, Manal Ismail Bokhary
DOI: 10.12659/AJCR.950688
Am J Case Rep 2026; 27:e950688
700 1344 0

17 Mar 2026 : Case report
Congenital Limb Duplication and Spinal Dysraphism: A Rare Case Report Highlighting Single-Stage Multidisciplinary Surgery and Life-Changing Outcome
Iman Dwi Winanto
, Jefryan Sofyan
, Tommy Mandagi
, Ricovially Davya Guci
, Abdurrahman Mouza
, Arya Tjipta Prananda
DOI: 10.12659/AJCR.951696
Am J Case Rep 2026; 27:e951696
696 1,604 0

17 Mar 2026 : Case report
Congenital Limb Duplication and Spinal Dysraphism: A Rare Case Report Highlighting Single-Stage Multidisciplinary Surgery and Life-Changing Outcome
Iman Dwi Winanto
, Jefryan Sofyan
, Tommy Mandagi
, Ricovially Davya Guci
, Abdurrahman Mouza
, Arya Tjipta Prananda
DOI: 10.12659/AJCR.951696
Am J Case Rep 2026; 27:e951696
696 1604 0

16 Mar 2026 : Case report
A 53-Year-Old Male Smoker With Advanced Oral Squamous Cell Carcinoma Associated With Paraneoplastic Leukemoid Reaction
DOI: 10.12659/AJCR.951056
Am J Case Rep 2026; 27:e951056
571 1,044 0

16 Mar 2026 : Case report
A 53-Year-Old Male Smoker With Advanced Oral Squamous Cell Carcinoma Associated With Paraneoplastic Leukemoid Reaction
DOI: 10.12659/AJCR.951056
Am J Case Rep 2026; 27:e951056
571 1044 0

16 Mar 2026 : Case report
Fatal Cardiomyopathy Secondary to Seronegative Immune-Mediated Necrotizing Myopathy: A Case Report
Benjamin D. Lueck, Alyssa K.W. Maclean, Georges El Hasbani, Andrew J. Layman, Floranne C. Ernste, Courtney A. Arment
DOI: 10.12659/AJCR.951603
Am J Case Rep 2026; 27:e951603
721 1,999 0

16 Mar 2026 : Case report
Fatal Cardiomyopathy Secondary to Seronegative Immune-Mediated Necrotizing Myopathy: A Case Report
Benjamin D. Lueck, Alyssa K.W. Maclean, Georges El Hasbani, Andrew J. Layman, Floranne C. Ernste, Courtney A. Arment
DOI: 10.12659/AJCR.951603
Am J Case Rep 2026; 27:e951603
721 1999 0

15 Mar 2026 : Case report
Delayed Recognition of Systemic Lupus Erythematosus Presenting With Visceral Muscle Dysmotility and Chronic Mucus-Bloody Enteropathy: A Case Report
Settanan Plangsiri
, Manisara Jirapornsuwan, Pat Ngamdachakij, Dhanesh Pitidhammabhorn, Wannisa Wongpipathpong
DOI: 10.12659/AJCR.950774
Am J Case Rep 2026; 27:e950774
544 1,351 0

15 Mar 2026 : Case report
Delayed Recognition of Systemic Lupus Erythematosus Presenting With Visceral Muscle Dysmotility and Chronic Mucus-Bloody Enteropathy: A Case Report
Settanan Plangsiri
, Manisara Jirapornsuwan, Pat Ngamdachakij, Dhanesh Pitidhammabhorn, Wannisa Wongpipathpong
DOI: 10.12659/AJCR.950774
Am J Case Rep 2026; 27:e950774
544 1351 0

14 Mar 2026 : Case report
A 43-Year-Old Man With Isolated Cutaneous Lymphomatoid Granulomatosis Presenting as a Chronic Necrotizing Ulcer of the Upper Arm
Adebola Oluwabusayo Adetiloye
, Anim Asif
, Olurotimi J. Badero
, Tan Zimri, Nadine C. Brissett-Williams
DOI: 10.12659/AJCR.951661
Am J Case Rep 2026; 27:e951661
557 835 0

14 Mar 2026 : Case report
A 43-Year-Old Man With Isolated Cutaneous Lymphomatoid Granulomatosis Presenting as a Chronic Necrotizing Ulcer of the Upper Arm
Adebola Oluwabusayo Adetiloye
, Anim Asif
, Olurotimi J. Badero
, Tan Zimri, Nadine C. Brissett-Williams
DOI: 10.12659/AJCR.951661
Am J Case Rep 2026; 27:e951661
557 835 0

12 Feb 2026 : Case report
Bilateral Adrenal Infarction as an Uncommon Complication of Heparin-Induced Thrombocytopenia: A Case Report
Abhinav Singla
, Asmita Addanki
, Aleena Shahnawaz
, Alyssa Catherine Raj
, Anam Sadia, Shah Rukh, Muhammad Ali
, Aleksandra Murawska Baptista
DOI: 10.12659/AJCR.951331
Am J Case Rep 2026; 27:e951331
812 1,319 0

12 Feb 2026 : Case report
Bilateral Adrenal Infarction as an Uncommon Complication of Heparin-Induced Thrombocytopenia: A Case Report
Abhinav Singla
, Asmita Addanki
, Aleena Shahnawaz
, Alyssa Catherine Raj
, Anam Sadia, Shah Rukh, Muhammad Ali
, Aleksandra Murawska Baptista
DOI: 10.12659/AJCR.951331
Am J Case Rep 2026; 27:e951331
812 1319 0

14 Mar 2026 : Case report
A Case of Uncommon Tuberculosis Infection Involving the Sternoclavicular Joint
Shrimahitha Duraiyarasan, Ruijia Hou, Audrey A. Boadu, Phelese Smith, Crisanta Simon
, Bethel Shiferaw
DOI: 10.12659/AJCR.949900
Am J Case Rep 2026; 27:e949900
527 1,382 0

14 Mar 2026 : Case report
A Case of Uncommon Tuberculosis Infection Involving the Sternoclavicular Joint
Shrimahitha Duraiyarasan, Ruijia Hou, Audrey A. Boadu, Phelese Smith, Crisanta Simon
, Bethel Shiferaw
DOI: 10.12659/AJCR.949900
Am J Case Rep 2026; 27:e949900
527 1382 0

13 Mar 2026 : Case report
A Challenging Case of Pleomorphic Lipoma of the Shoulder Mimicking Liposarcoma
Yunan Han
, Abid Qureshi, Haleigh M. Heubeck, Yingxian Liu, Luca Milone
DOI: 10.12659/AJCR.950876
Am J Case Rep 2026; 27:e950876
455 858 0

13 Mar 2026 : Case report
A Challenging Case of Pleomorphic Lipoma of the Shoulder Mimicking Liposarcoma
Yunan Han
, Abid Qureshi, Haleigh M. Heubeck, Yingxian Liu, Luca Milone
DOI: 10.12659/AJCR.950876
Am J Case Rep 2026; 27:e950876
455 858 0

12 Mar 2026 : Case report
Anastomotic-Transverse Colon Fistula Following Gastrectomy: A Case Report of Delayed Diagnosis 14 Years After Surgery
Yalan Xu, Zhongshu Li, Wenjia Tian, Ning Chen
DOI: 10.12659/AJCR.951102
Am J Case Rep 2026; 27:e951102
511 993 0

12 Mar 2026 : Case report
Anastomotic-Transverse Colon Fistula Following Gastrectomy: A Case Report of Delayed Diagnosis 14 Years After Surgery
Yalan Xu, Zhongshu Li, Wenjia Tian, Ning Chen
DOI: 10.12659/AJCR.951102
Am J Case Rep 2026; 27:e951102
511 993 0

12 Mar 2026 : Case report
Systemic Lupus Erythematosus With IgA Nephropathy: Challenges in Diagnosis and Management
Mandar Shah
, Farheen Malik
, Mihika Shah
, Maurya Devang Patel
, Rutika Pathakjee
, Sapan Pandya
DOI: 10.12659/AJCR.951908
Am J Case Rep 2026; 27:e951908
569 1,567 0

12 Mar 2026 : Case report
Systemic Lupus Erythematosus With IgA Nephropathy: Challenges in Diagnosis and Management
Mandar Shah
, Farheen Malik
, Mihika Shah
, Maurya Devang Patel
, Rutika Pathakjee
, Sapan Pandya
DOI: 10.12659/AJCR.951908
Am J Case Rep 2026; 27:e951908
569 1567 0

11 Mar 2026 : Case report
Capsaicin-Triggered Vaginal Burning Due to Obstructed Rectovaginal Fistula: A Rare Case of Perineal Coproliths
Yujiao Wu, Weizheng Huang, Yong Wen, Cengzi Huang, Yaling Li, Jun Li
DOI: 10.12659/AJCR.950337
Am J Case Rep 2026; 27:e950337
750 1,503 0

11 Mar 2026 : Case report
Capsaicin-Triggered Vaginal Burning Due to Obstructed Rectovaginal Fistula: A Rare Case of Perineal Coproliths
Yujiao Wu, Weizheng Huang, Yong Wen, Cengzi Huang, Yaling Li, Jun Li
DOI: 10.12659/AJCR.950337
Am J Case Rep 2026; 27:e950337
750 1503 0

11 Mar 2026 : Case report
Unrepaired Truncus Arteriosus Type 1 With Eisenmenger Syndrome and Recurrent Embolic Strokes: An Adult Case Report
Osama A. Abdulrahman, Mohammad F. Babgi, Jameel T. Alrefai, Atiqah H. Alfahmi, Shaimaa H. Oraif, Nada Bakhsh, Fatma Aboul-Enein
, Ahemd M. Samman
DOI: 10.12659/AJCR.951421
Am J Case Rep 2026; 27:e951421
708 1,041 0

11 Mar 2026 : Case report
Unrepaired Truncus Arteriosus Type 1 With Eisenmenger Syndrome and Recurrent Embolic Strokes: An Adult Case Report
Osama A. Abdulrahman, Mohammad F. Babgi, Jameel T. Alrefai, Atiqah H. Alfahmi, Shaimaa H. Oraif, Nada Bakhsh, Fatma Aboul-Enein
, Ahemd M. Samman
DOI: 10.12659/AJCR.951421
Am J Case Rep 2026; 27:e951421
708 1041 0
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Am J Case Rep In Press; DOI: 10.12659/AJCR.952980
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