Challenging differential diagnosis

30 Jul 2026 : Case report
Management of Shamblin Type III Carotid Body Tumor With Preoperative Embolization, Surgical Resection, and Rescue Endovascular Stroke Treatment: A Case Report
Michal S. Proczka
, Piotr Kaszczewski
, Michał M. Sajdek, Amelia Maciąg, Rafał Maciąg, Ireneusz Nawrot
, Zbigniew Gałązka
DOI: 10.12659/AJCR.951348
Am J Case Rep 2026; 27:e951348
296 164 0

30 Jul 2026 : Case report
Management of Shamblin Type III Carotid Body Tumor With Preoperative Embolization, Surgical Resection, and Rescue Endovascular Stroke Treatment: A Case Report
Michal S. Proczka
, Piotr Kaszczewski
, Michał M. Sajdek, Amelia Maciąg, Rafał Maciąg, Ireneusz Nawrot
, Zbigniew Gałązka
DOI: 10.12659/AJCR.951348
Am J Case Rep 2026; 27:e951348
296 164 0

28 Jul 2026 : Case report
Acute Small Bowel Obstruction as the First Manifestation of Occult Lung Adenocarcinoma: A Case Report of Jejunal Metastasis
Midani Touati, Ibtissem Korbi, Hiba Ben Hassine, Faiez Boughanmi
, Manel Njima, Sofiene Gaied Chortane, Faouzi Noomen
DOI: 10.12659/AJCR.953993
Am J Case Rep 2026; 27:e953993
397 212 0

28 Jul 2026 : Case report
Acute Small Bowel Obstruction as the First Manifestation of Occult Lung Adenocarcinoma: A Case Report of Jejunal Metastasis
Midani Touati, Ibtissem Korbi, Hiba Ben Hassine, Faiez Boughanmi
, Manel Njima, Sofiene Gaied Chortane, Faouzi Noomen
DOI: 10.12659/AJCR.953993
Am J Case Rep 2026; 27:e953993
397 212 0

21 Jul 2026 : Case report
Tuberculosis in the Context of Idiopathic CD4 Lymphocytopenia: A Case Report and Literature Review
Sara M. Alwarthan
, Abir Hamad Alsaid, Ashraf Ezzat Abdelsamad Attia
, Ahmed Alsahlawi
, Shahad Ali AlZahrani
, Khalid Ghazai Alotaibi
, Hassan Naasr Al Dhneem
, Marwan Jabr Alwazzeh
DOI: 10.12659/AJCR.953101
Am J Case Rep 2026; 27:e953101
339 342 0

21 Jul 2026 : Case report
Tuberculosis in the Context of Idiopathic CD4 Lymphocytopenia: A Case Report and Literature Review
Sara M. Alwarthan
, Abir Hamad Alsaid, Ashraf Ezzat Abdelsamad Attia
, Ahmed Alsahlawi
, Shahad Ali AlZahrani
, Khalid Ghazai Alotaibi
, Hassan Naasr Al Dhneem
, Marwan Jabr Alwazzeh
DOI: 10.12659/AJCR.953101
Am J Case Rep 2026; 27:e953101
339 342 0

17 Jul 2026 : Case report
Acquired Hemophilia A Revealing Occult Splenic Marginal Zone Lymphoma
Haripriya Susmitha Brahmanapalle, Alka Arora
DOI: 10.12659/AJCR.953683
Am J Case Rep 2026; 27:e953683
268 317 0

17 Jul 2026 : Case report
Acquired Hemophilia A Revealing Occult Splenic Marginal Zone Lymphoma
Haripriya Susmitha Brahmanapalle, Alka Arora
DOI: 10.12659/AJCR.953683
Am J Case Rep 2026; 27:e953683
268 317 0

16 Jul 2026 : Case report
Heyde Syndrome Complicated by Pulmonary Embolism Before Transcatheter Aortic Valve Replacement: A Clinical Dilemma Between Bleeding and Thrombosis
Mingying Cao, Lingli Zhang, Ying Ren, Gejun Zhang
DOI: 10.12659/AJCR.953608
Am J Case Rep 2026; 27:e953608
353 312 0

16 Jul 2026 : Case report
Heyde Syndrome Complicated by Pulmonary Embolism Before Transcatheter Aortic Valve Replacement: A Clinical Dilemma Between Bleeding and Thrombosis
Mingying Cao, Lingli Zhang, Ying Ren, Gejun Zhang
DOI: 10.12659/AJCR.953608
Am J Case Rep 2026; 27:e953608
353 312 0

10 Jul 2026 : Case report
Thoracolaparoscopic Esophagectomy for Severe Post-Corrosive Esophageal Stricture in a Young Adult: Implications for Minimally Invasive Surgical Practice
Kuanysh Kanatov
, Adil Shokebaev
, Bolatbek Baimakhanov
, Shakir Zhurayev
, Gulziya Ismailova
, Nurmakhan Imammyrzayev
, Nurbol Orynbassar
, Nazar Tolkyn
, Khozybek Kazakhstan
, Utkalbayev Garifulla
DOI: 10.12659/AJCR.953371
Am J Case Rep 2026; 27:e953371
321 370 0

10 Jul 2026 : Case report
Thoracolaparoscopic Esophagectomy for Severe Post-Corrosive Esophageal Stricture in a Young Adult: Implications for Minimally Invasive Surgical Practice
Kuanysh Kanatov
, Adil Shokebaev
, Bolatbek Baimakhanov
, Shakir Zhurayev
, Gulziya Ismailova
, Nurmakhan Imammyrzayev
, Nurbol Orynbassar
, Nazar Tolkyn
, Khozybek Kazakhstan
, Utkalbayev Garifulla
DOI: 10.12659/AJCR.953371
Am J Case Rep 2026; 27:e953371
321 370 0

09 Jul 2026 : Case report
Anterior ST-Segment Elevation Myocardial Infarction Shortly After Cefaclor Exposure: A Case Report Highlighting Kounis Syndrome as a Differential Diagnosis
Quan Zuo, Yue Zhu, Zhiwei Wang, Tao Ge
DOI: 10.12659/AJCR.953705
Am J Case Rep 2026; 27:e953705
406 386 0

09 Jul 2026 : Case report
Anterior ST-Segment Elevation Myocardial Infarction Shortly After Cefaclor Exposure: A Case Report Highlighting Kounis Syndrome as a Differential Diagnosis
Quan Zuo, Yue Zhu, Zhiwei Wang, Tao Ge
DOI: 10.12659/AJCR.953705
Am J Case Rep 2026; 27:e953705
406 386 0

08 Jul 2026 : Case report
A 31-Year-Old Woman With Liver Cirrhosis Due to Wilson Disease and the Double Impact of Active Tuberculosis and Anti-Tuberculosis Therapy Resulting in Acute Liver Injury
Petar Trifonov, Sonya Stefkova Dragneva, Donika K. Todovichin, Ivana Tihomirova Kitaeva, Rosen K. Nikolov
DOI: 10.12659/AJCR.953050
Am J Case Rep 2026; 27:e953050
440 440 0

08 Jul 2026 : Case report
A 31-Year-Old Woman With Liver Cirrhosis Due to Wilson Disease and the Double Impact of Active Tuberculosis and Anti-Tuberculosis Therapy Resulting in Acute Liver Injury
Petar Trifonov, Sonya Stefkova Dragneva, Donika K. Todovichin, Ivana Tihomirova Kitaeva, Rosen K. Nikolov
DOI: 10.12659/AJCR.953050
Am J Case Rep 2026; 27:e953050
440 440 0

12 Aug 2026 : Case report
Solitary Peritoneal Metastasis of AFP-Negative Hepatocellular Carcinoma in a 65-Year-Old Man with a History of Lung Adenocarcinoma: A Case Report
Zhineng Xie, Jie Huang, Kailong Fu
DOI: 10.12659/AJCR.953374
Am J Case Rep 2026; 27:e953374
156 189 0

12 Aug 2026 : Case report
Solitary Peritoneal Metastasis of AFP-Negative Hepatocellular Carcinoma in a 65-Year-Old Man with a History of Lung Adenocarcinoma: A Case Report
Zhineng Xie, Jie Huang, Kailong Fu
DOI: 10.12659/AJCR.953374
Am J Case Rep 2026; 27:e953374
156 189 0

10 Aug 2026 : Case report
Massive Inferior Vena Cava Thrombosis and Pulmonary Embolism Secondary to Hepatic Hydatid Cyst: A Fatal Case
Abdulrahman Alozaymi, Roaa Amer
, Abdulaziz Fahad Alsayari
DOI: 10.12659/AJCR.952041
Am J Case Rep 2026; 27:e952041
298 185 0

10 Aug 2026 : Case report
Massive Inferior Vena Cava Thrombosis and Pulmonary Embolism Secondary to Hepatic Hydatid Cyst: A Fatal Case
Abdulrahman Alozaymi, Roaa Amer
, Abdulaziz Fahad Alsayari
DOI: 10.12659/AJCR.952041
Am J Case Rep 2026; 27:e952041
298 185 0

09 Aug 2026 : Case report
Invasive Breast Cancer Complicated by Colitis After TCbHP Chemotherapy: A Case Report
Zicong You
, Yue Deng, Shiying Cao, Fei Wang
DOI: 10.12659/AJCR.952507
Am J Case Rep 2026; 27:e952507
286 179 0

09 Aug 2026 : Case report
Invasive Breast Cancer Complicated by Colitis After TCbHP Chemotherapy: A Case Report
Zicong You
, Yue Deng, Shiying Cao, Fei Wang
DOI: 10.12659/AJCR.952507
Am J Case Rep 2026; 27:e952507
286 179 0

07 Aug 2026 : Case report
Clear Cell Carcinoma of the Left Colon: A Case Report
Mohamed Ahmed
, Abubaker K.S. Khalid
, Olive Cummins
, Kate Richards
DOI: 10.12659/AJCR.952922
Am J Case Rep 2026; 27:e952922
305 183 0

07 Aug 2026 : Case report
Clear Cell Carcinoma of the Left Colon: A Case Report
Mohamed Ahmed
, Abubaker K.S. Khalid
, Olive Cummins
, Kate Richards
DOI: 10.12659/AJCR.952922
Am J Case Rep 2026; 27:e952922
305 183 0

06 Aug 2026 : Case report
Perioperative Anaphylactic Shock Induced by Cisatracurium: A Case Demonstrating the Diagnostic and Clinical Value of Early Skin Testing
Yu Ying, Shenglan Tian, Jingli Chen, Keding Wang, Shenghua Li
DOI: 10.12659/AJCR.952854
Am J Case Rep 2026; 27:e952854
304 154 0

06 Aug 2026 : Case report
Perioperative Anaphylactic Shock Induced by Cisatracurium: A Case Demonstrating the Diagnostic and Clinical Value of Early Skin Testing
Yu Ying, Shenglan Tian, Jingli Chen, Keding Wang, Shenghua Li
DOI: 10.12659/AJCR.952854
Am J Case Rep 2026; 27:e952854
304 154 0

05 Aug 2026 : Case report
Chest Pain Due to Anomalous Origin of the Left Circumflex Artery From the Opposite Sinus of Valsalva in a 70-Year-Old Woman
Tian Luo, Kang Luo, JunBing Lin, Qiang Huang
DOI: 10.12659/AJCR.952577
Am J Case Rep 2026; 27:e952577
319 140 0

05 Aug 2026 : Case report
Chest Pain Due to Anomalous Origin of the Left Circumflex Artery From the Opposite Sinus of Valsalva in a 70-Year-Old Woman
Tian Luo, Kang Luo, JunBing Lin, Qiang Huang
DOI: 10.12659/AJCR.952577
Am J Case Rep 2026; 27:e952577
319 140 0

22 Jun 2026 : Case report
Suspected Adult-Onset Congenital Myasthenic Syndrome Associated With a Heterozygous CHRND Variant in a Patient With Seropositive Rheumatoid Arthritis: A Case Report
Khaled Abdulwahab Amer
, Hanan Hassan Almalki
, Faisal Saud Alhudaithi
DOI: 10.12659/AJCR.952887
Am J Case Rep 2026; 27:e952887
485 599 0

22 Jun 2026 : Case report
Suspected Adult-Onset Congenital Myasthenic Syndrome Associated With a Heterozygous CHRND Variant in a Patient With Seropositive Rheumatoid Arthritis: A Case Report
Khaled Abdulwahab Amer
, Hanan Hassan Almalki
, Faisal Saud Alhudaithi
DOI: 10.12659/AJCR.952887
Am J Case Rep 2026; 27:e952887
485 599 0

04 Aug 2026 : Case report
Coexistence of Neurofibromatosis Type 1 and Marfan Syndrome in a 13-Year-Old Boy: A Case Report
Piotr Wieniawski
, Magdalena Warych
, Beata Kucińska
, Izabela Janiec, Bożena Werner
DOI: 10.12659/AJCR.950868
Am J Case Rep 2026; 27:e950868
510 313 0

04 Aug 2026 : Case report
Coexistence of Neurofibromatosis Type 1 and Marfan Syndrome in a 13-Year-Old Boy: A Case Report
Piotr Wieniawski
, Magdalena Warych
, Beata Kucińska
, Izabela Janiec, Bożena Werner
DOI: 10.12659/AJCR.950868
Am J Case Rep 2026; 27:e950868
510 313 0

03 Aug 2026 : Case report
Pustules in Stevens-Johnson Syndrome
Shunya Nagata, Takaie Kuki, Miyuki Kato
DOI: 10.12659/AJCR.953161
Am J Case Rep 2026; 27:e953161
388 314 0

03 Aug 2026 : Case report
Pustules in Stevens-Johnson Syndrome
Shunya Nagata, Takaie Kuki, Miyuki Kato
DOI: 10.12659/AJCR.953161
Am J Case Rep 2026; 27:e953161
388 314 0

03 Aug 2026 : Case report
Acute Appendicitis as a Precipitating Factor for Diabetic Ketosis in Newly Diagnosed Type 2 Diabetes Mellitus: A Case Report
Ziyang Wang, Meijia Yang
DOI: 10.12659/AJCR.952909
Am J Case Rep 2026; 27:e952909
441 313 0

03 Aug 2026 : Case report
Acute Appendicitis as a Precipitating Factor for Diabetic Ketosis in Newly Diagnosed Type 2 Diabetes Mellitus: A Case Report
Ziyang Wang, Meijia Yang
DOI: 10.12659/AJCR.952909
Am J Case Rep 2026; 27:e952909
441 313 0

02 Aug 2026 : Case report
Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis Presenting as Pyrexia of Unknown Origin With Splenic Masses
Nidhi Gupta, Kriti Yadav, Mythri Chittilla, Charly Almonte, Rahul Sampath
DOI: 10.12659/AJCR.952791
Am J Case Rep 2026; 27:e952791
480 361 0

02 Aug 2026 : Case report
Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis Presenting as Pyrexia of Unknown Origin With Splenic Masses
Nidhi Gupta, Kriti Yadav, Mythri Chittilla, Charly Almonte, Rahul Sampath
DOI: 10.12659/AJCR.952791
Am J Case Rep 2026; 27:e952791
480 361 0

17 Jun 2026 : Case report
Chlamydia trachomatis Pneumonia in a 50-Day-Old Full-Term Male Infant Associated With Mucus Plugging of the Left Upper Lobe Bronchus and Left Upper Lobe Atelectasis
Yuan Huang
, Meixia Huang, Liqin Ke, Shuxian Li, Xiaofen Tao, Guohong Zhu
DOI: 10.12659/AJCR.953643
Am J Case Rep 2026; 27:e953643
460 769 0

17 Jun 2026 : Case report
Chlamydia trachomatis Pneumonia in a 50-Day-Old Full-Term Male Infant Associated With Mucus Plugging of the Left Upper Lobe Bronchus and Left Upper Lobe Atelectasis
Yuan Huang
, Meixia Huang, Liqin Ke, Shuxian Li, Xiaofen Tao, Guohong Zhu
DOI: 10.12659/AJCR.953643
Am J Case Rep 2026; 27:e953643
460 769 0

01 Aug 2026 : Case report
Continuous Epidural Infusion of Hydroxyethyl Starch for Spontaneous Intracranial Hypotension: A Retrospective Case Series
Xiao-Yan Zhang
, Qiu-Li Zhang, Ying Liu, Li-Jie Zhu, Ying-Zhi Li, Xi-Ying Ye, Zhong-Jun Zhang, Yao-Xian Zhang
DOI: 10.12659/AJCR.953129
Am J Case Rep 2026; 27:e953129
379 332 0

01 Aug 2026 : Case report
Continuous Epidural Infusion of Hydroxyethyl Starch for Spontaneous Intracranial Hypotension: A Retrospective Case Series
Xiao-Yan Zhang
, Qiu-Li Zhang, Ying Liu, Li-Jie Zhu, Ying-Zhi Li, Xi-Ying Ye, Zhong-Jun Zhang, Yao-Xian Zhang
DOI: 10.12659/AJCR.953129
Am J Case Rep 2026; 27:e953129
379 332 0

29 Jul 2026 : Case report
Coronary Artery Embolism From Atrial Flutter Presenting as Cardiac Arrest and ST-Elevation Myocardial Infarction: Diagnostic and Therapeutic Challenges
Keyshla Pagán Morales, Keyur Patel
, Ammar Ahmed, Marcel Zughaib
DOI: 10.12659/AJCR.952062
Am J Case Rep 2026; 27:e952062
451 395 0

29 Jul 2026 : Case report
Coronary Artery Embolism From Atrial Flutter Presenting as Cardiac Arrest and ST-Elevation Myocardial Infarction: Diagnostic and Therapeutic Challenges
Keyshla Pagán Morales, Keyur Patel
, Ammar Ahmed, Marcel Zughaib
DOI: 10.12659/AJCR.952062
Am J Case Rep 2026; 27:e952062
451 395 0

30 Jul 2026 : Case report
Thoracic SMARCA4-Deficient Undifferentiated Tumor Presenting as a Giant Mediastinal Mass: A Case Report
Nanami Ichihashi, Motona Kumagai
, Miyako Shimasaki, Akihiro Shioya
, Sohsuke Yamada
DOI: 10.12659/AJCR.952937
Am J Case Rep 2026; 27:e952937
417 399 0

30 Jul 2026 : Case report
Thoracic SMARCA4-Deficient Undifferentiated Tumor Presenting as a Giant Mediastinal Mass: A Case Report
Nanami Ichihashi, Motona Kumagai
, Miyako Shimasaki, Akihiro Shioya
, Sohsuke Yamada
DOI: 10.12659/AJCR.952937
Am J Case Rep 2026; 27:e952937
417 399 0

27 Jul 2026 : Case report
Transient Cardiac Dysfunction Due to New-Onset Mitral Chordal Rupture With Concomitant Congenital Absence of the Right Coronary Artery: A Case Report
Songyan Zhang, Ying Cui, Shucheng Li
DOI: 10.12659/AJCR.952798
Am J Case Rep 2026; 27:e952798
333 313 0

27 Jul 2026 : Case report
Transient Cardiac Dysfunction Due to New-Onset Mitral Chordal Rupture With Concomitant Congenital Absence of the Right Coronary Artery: A Case Report
Songyan Zhang, Ying Cui, Shucheng Li
DOI: 10.12659/AJCR.952798
Am J Case Rep 2026; 27:e952798
333 313 0

25 Jul 2026 : Case report
A 46-Year-Old Man Presenting With Chest Pain Due to Apical Hypertrophic Cardiomyopathy (Yamaguchi Syndrome) Diagnosed by Multimodal Cardiac Imaging
Mauro de Deus Passos, Daniel Lopes Marques de Araújo, Lucas de Ávila Mariano, Dilson Palhares Ferreira, Luciano Moreira Alves, Simone Nascimento dos Santos
DOI: 10.12659/AJCR.953259
Am J Case Rep 2026; 27:e953259
448 468 0

25 Jul 2026 : Case report
A 46-Year-Old Man Presenting With Chest Pain Due to Apical Hypertrophic Cardiomyopathy (Yamaguchi Syndrome) Diagnosed by Multimodal Cardiac Imaging
Mauro de Deus Passos, Daniel Lopes Marques de Araújo, Lucas de Ávila Mariano, Dilson Palhares Ferreira, Luciano Moreira Alves, Simone Nascimento dos Santos
DOI: 10.12659/AJCR.953259
Am J Case Rep 2026; 27:e953259
448 468 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.952748
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953273
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Am J Case Rep In Press; DOI: 10.12659/AJCR.952861
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Am J Case Rep In Press; DOI: 10.12659/AJCR.953155
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